iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132276

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAMC01088073

Gene Name

KLHL11; klhl11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000032476.1	ENSXETT00000063361.1	ENSXETP00000062590.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	7.40e-15	55.3	58	129
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.70e-10	39.4	164	194

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvg..geeffahkivLaasSsvFyalflmeleesksklmveik...d..vqpevfrallkFlYtgkld 66
           +D++lv g  g+ef+ah++vLaa+ ++F  l+++++ees+ +++v++k   +   + e ++a+++++Ytg+++
   Q: 58   CDMTLVFGqgGREFPAHRSVLAAATDYFAPLLSGQFEESR-SGRVDMKwssEpgPDLETVEAVIQYMYTGQIR 129
           8******889******************************.*******9643789999************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           l+Nc++i ++A++y++++L+++  ++i ++F
   Q: 164  LSNCVAIHSLAHMYSLTQLALKSAEMIRRNF 194
           69****************************9 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MAEATAIALI PSPQQPLPEP EPQDGAPEDW EAEMFMSGTH CTDLAWRQNE QRKQGQFCDM 60
TLVFGQGGRE FPAHRSVLAA ATDYFAPLLS GQFEESRSGR VDMKWSSEPG PDLETVEAVI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAAG CAACAGCGAT TGCGCTTATC CCATCCCCTC AGCAGCCGCT GCCGGAACCG 60
GAGCCGCAGG ATGGGGCCCC TGAGGACTGG GAAGCGGAAA TGTTCATGTC CGGGACTCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030162--P:regulation of proteolysis

KEGG

xtr:100491061

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002239	Ailuropoda melanoleuca	76.64	0.00e+00	1032.00
IUUC-Apl-003928	Anas platyrhynchos	77.91	0.00e+00	941.00
IUUC-Aca-004801	Anolis carolinensis	76.64	0.00e+00	1011.00
IUUC-Ame-010943	Astyanax mexicanus	76.07	0.00e+00	880.00
IUUC-Bta-012341	Bos taurus	83.73	4.00e-82	296.00
IUUC-Cja-019924	Callithrix jacchus	77.41	0.00e+00	1053.00
IUUC-Cfa-021076	Canis familiaris	77.73	0.00e+00	1058.00
IUUC-Cpo-022193	Cavia porcellus	77.29	0.00e+00	1037.00
IUUC-Csa-023614	Chlorocebus sabaeus	77.26	0.00e+00	1050.00
IUUC-Cho-024806	Choloepus hoffmanni	65.40	0.00e+00	689.00
IUUC-Dre-028622	Danio rerio	74.10	0.00e+00	952.00
IUUC-Dno-029965	Dasypus novemcinctus	75.54	0.00e+00	1019.00
IUUC-Dor-030136	Dipodomys ordii	78.14	0.00e+00	882.00
IUUC-Eca-034191	Equus caballus	76.91	0.00e+00	1046.00
IUUC-Eeu-034746	Erinaceus europaeus	77.10	0.00e+00	1047.00
IUUC-Fca-035702	Felis catus	72.09	0.00e+00	948.00
IUUC-Fal-037360	Ficedula albicollis	79.86	0.00e+00	949.00
IUUC-Gmo-038582	Gadus morhua	75.36	0.00e+00	963.00
IUUC-Ggr-039747	Gaeumannomyces graminis	24.06	4.00e-08	51.60
IUUC-Gga-040375	Gallus gallus	76.79	0.00e+00	1025.00
IUUC-Gac-042523	Gasterosteus aculeatus	75.88	0.00e+00	953.00
IUUC-Ggo-045632	Gorilla gorilla	78.03	0.00e+00	879.00
IUUC-Hsa-046817	Homo sapiens	77.26	0.00e+00	1051.00
IUUC-Itr-048433	Ictidomys tridecemlineatus	77.57	0.00e+00	1058.00
IUUC-Lch-049985	Latimeria chalumnae	77.61	0.00e+00	990.00
IUUC-Loc-052594	Lepisosteus oculatus	75.72	0.00e+00	957.00
IUUC-Lma-053111	Leptosphaeria maculans	32.84	2.00e-04	39.70
IUUC-Laf-054357	Loxodonta africana	77.73	0.00e+00	1060.00
IUUC-Mcc-055454	Macaca mulatta	77.26	0.00e+00	1050.00
IUUC-Meu-056012	Macropus eugenii	77.08	8.00e-140	489.00
IUUC-Mga-060048	Meleagris gallopavo	77.80	0.00e+00	789.00
IUUC-Mdo-062082	Monodelphis domestica	78.19	0.00e+00	1071.00
IUUC-Mmu-063119	Mus musculus	77.41	0.00e+00	1056.00
IUUC-Mpu-066511	Mustela putorius furo	77.57	0.00e+00	1058.00
IUUC-Mlu-067301	Myotis lucifugus	77.95	0.00e+00	1053.00
IUUC-Nle-069912	Nomascus leucogenys	77.26	0.00e+00	1051.00
IUUC-Opr-070762	Ochotona princeps	75.74	0.00e+00	657.00
IUUC-Ont-071916	Oreochromis niloticus	76.75	0.00e+00	955.00
IUUC-Oan-072932	Ornithorhynchus anatinus	70.97	0.00e+00	751.00
IUUC-Ocu-074172	Oryctolagus cuniculus	78.46	0.00e+00	873.00
IUUC-Ola-086483	Oryzias latipes	76.10	0.00e+00	949.00
IUUC-Oga-088112	Otolemur garnettii	76.90	0.00e+00	1018.00
IUUC-Oar-090129	Ovis aries	77.57	0.00e+00	1056.00
IUUC-Ptr-090571	Pan troglodytes	77.95	0.00e+00	876.00
IUUC-Pan-092073	Papio anubis	77.26	0.00e+00	1050.00
IUUC-Psi-093836	Pelodiscus sinensis	77.76	0.00e+00	972.00
IUUC-Pno-094928	Phaeosphaeria nodorum	37.31	1.00e-05	43.10
IUUC-Pfo-096477	Poecilia formosa	76.42	0.00e+00	951.00
IUUC-Pab-098473	Pongo abelii	77.26	0.00e+00	1051.00
IUUC-Pca-100239	Procavia capensis	79.00	0.00e+00	629.00
IUUC-Pyt-104638	Pyrenophora triticirepentis	38.81	1.00e-05	43.50
IUUC-Rno-104859	Rattus norvegicus	77.57	0.00e+00	1056.00
IUUC-Sha-106746	Sarcophilus harrisii	78.32	0.00e+00	1069.00
IUUC-Tgu-117183	Taeniopygia guttata	77.62	0.00e+00	1032.00
IUUC-Tru-118655	Takifugu rubripes	74.40	0.00e+00	936.00
IUUC-Tsy-119430	Tarsius syrichta	77.12	0.00e+00	1049.00
IUUC-Tni-119698	Tetraodon nigroviridis	75.36	0.00e+00	842.00
IUUC-Vda-129848	Verticillium dahliae	31.34	1.00e-03	37.00
IUUC-Vpa-130715	Vicugna pacos	77.41	0.00e+00	1046.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence