iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033743

Ensembl Protein ID

ENSECAP00000016384.1

UniProt Accession

F7AV69; F7AV69_HORSE

Protein Name

Uncharacterized protein

Gene Name

UBASH3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000018634.1	ENSECAT00000019982.1	ENSECAP00000016384.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.20e-22	76.9	209	272
UBD/Alpha-Helix/UBA	9.50e-07	28.9	1	30

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlvi..ekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++e++qv+y+y++qnddeL+l  Gd++++   e+++++egW++g++ ++g++Gl+Pen+++k++
   Q: 209  NHETLQVIYPYTPQNDDELELVPGDFIFMSpmEQTSTSEGWIYGTSLTTGCSGLLPENYITKAD 272
           6899*********************************************************987 PP

UBD/Alpha-Helix/UBA

   S: 13   MGFdreealqaLraa.nnnleaAveyLldg 41
           MGF+r +a++aL+++ + +++aA+++L+++
   Q: 1    MGFPRARAQKALASTgGRSVQAACDWLFSH 30
           ****************************97 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MGFPRARAQK ALASTGGRSV QAACDWLFSH VGDPFLDDPL PREYVLYLRP TGPLAQKLSD 60
FWQQSKQICG KNKAHNIFPH ITLCQFFMCE DSKVDALGEA LQTTVSRWKC KFSAPLPLEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCTCCCTCC TCCTCCCGGA CGCTTCGGCT CGGGTGCCTT CCCCGGCGAT GGCTGGCCGC 60
TGAGCCATGG CTCAGTACGG CCACCCCAGC CCGCTCGGCA TGGCCGCGAG AGAGGAGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009097--cNuc_Pdiesterase
IPR013078--His_Pase_superF_clade-1
IPR029033--His_PPase_superfam
IPR001452--SH3_domain
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50002--SH3
PS50030--UBA

Pfam

PF00300--His_Phos_1
PF14604--SH3_9
PF00627--UBA

SMART

SM00326--SH3

Gene Ontology

GO:0004725--F:protein tyrosine phosphatase activity
GO:0045779--P:negative regulation of bone resorption
GO:0045671--P:negative regulation of osteoclast differentiation
GO:0090331--P:negative regulation of platelet aggregation
GO:0006469--P:negative regulation of protein kinase activity
GO:0009968--P:negative regulation of signal transduction
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002126	Ailuropoda melanoleuca	98.01	0.00e+00	1212.00
IUUC-Apl-004080	Anas platyrhynchos	90.62	0.00e+00	1102.00
IUUC-Aca-004828	Anolis carolinensis	83.94	0.00e+00	1038.00
IUUC-Ame-011030	Astyanax mexicanus	73.80	0.00e+00	827.00
IUUC-Bta-012370	Bos taurus	98.99	0.00e+00	1207.00
IUUC-Bci-013728	Botrytis cinerea	28.14	6.00e-10	57.80
IUUC-Cel-018530	Caenorhabditis elegans	39.69	4.00e-51	194.00
IUUC-Cja-018758	Callithrix jacchus	98.51	0.00e+00	1192.00
IUUC-Cfa-020544	Canis familiaris	98.26	0.00e+00	1028.00
IUUC-Cpo-022044	Cavia porcellus	97.65	0.00e+00	1190.00
IUUC-Csa-024169	Chlorocebus sabaeus	98.18	0.00e+00	1187.00
IUUC-Cho-024498	Choloepus hoffmanni	80.17	0.00e+00	895.00
IUUC-Cin-025372	Ciona intestinalis	41.22	1.00e-57	217.00
IUUC-Csv-026379	Ciona savignyi	44.05	7.00e-73	267.00
IUUC-Cgl-026592	Colletotrichum gloeosporioides	29.08	2.00e-08	52.80
IUUC-Dre-027539	Danio rerio	73.89	0.00e+00	950.00
IUUC-Dno-029808	Dasypus novemcinctus	96.75	0.00e+00	699.00
IUUC-Dor-030582	Dipodomys ordii	80.76	0.00e+00	956.00
IUUC-Dme-032201	Drosophila melanogaster	38.67	3.00e-63	236.00
IUUC-Ete-032740	Echinops telfairi	77.61	0.00e+00	953.00
IUUC-Eeu-034505	Erinaceus europaeus	85.97	0.00e+00	700.00
IUUC-Fca-036519	Felis catus	98.34	0.00e+00	1222.00
IUUC-Fal-037295	Ficedula albicollis	89.93	0.00e+00	1099.00
IUUC-Gmo-038650	Gadus morhua	72.61	0.00e+00	879.00
IUUC-Gga-040179	Gallus gallus	90.89	0.00e+00	1129.00
IUUC-Gac-042180	Gasterosteus aculeatus	72.65	0.00e+00	882.00
IUUC-Ggo-044581	Gorilla gorilla	98.51	0.00e+00	1192.00
IUUC-Hsa-046526	Homo sapiens	98.34	0.00e+00	1191.00
IUUC-Itr-048502	Ictidomys tridecemlineatus	95.58	0.00e+00	640.00
IUUC-Lch-049576	Latimeria chalumnae	80.90	0.00e+00	1011.00
IUUC-Loc-051854	Lepisosteus oculatus	79.36	0.00e+00	931.00
IUUC-Laf-054177	Loxodonta africana	97.18	0.00e+00	1203.00
IUUC-Mcc-055185	Macaca mulatta	98.34	0.00e+00	1190.00
IUUC-Meu-056216	Macropus eugenii	92.49	0.00e+00	1009.00
IUUC-Mga-059564	Meleagris gallopavo	90.60	0.00e+00	1104.00
IUUC-Mmr-060934	Microcebus murinus	98.51	0.00e+00	1193.00
IUUC-Mdo-062955	Monodelphis domestica	95.70	0.00e+00	1165.00
IUUC-Mmu-063301	Mus musculus	97.35	0.00e+00	1211.00
IUUC-Mpu-066416	Mustela putorius furo	98.67	0.00e+00	1222.00
IUUC-Mlu-067833	Myotis lucifugus	87.81	0.00e+00	1025.00
IUUC-Nle-069367	Nomascus leucogenys	97.84	0.00e+00	1184.00
IUUC-Opr-070879	Ochotona princeps	84.82	0.00e+00	753.00
IUUC-Ont-072540	Oreochromis niloticus	74.46	0.00e+00	899.00
IUUC-Oan-073124	Ornithorhynchus anatinus	89.75	0.00e+00	885.00
IUUC-Ocu-074796	Oryctolagus cuniculus	97.51	0.00e+00	1185.00
IUUC-Ola-087253	Oryzias latipes	72.74	0.00e+00	901.00
IUUC-Oga-088406	Otolemur garnettii	92.87	0.00e+00	1134.00
IUUC-Oar-090262	Ovis aries	98.84	0.00e+00	1197.00
IUUC-Ptr-091014	Pan troglodytes	98.51	0.00e+00	1192.00
IUUC-Pan-092684	Papio anubis	98.34	0.00e+00	1190.00
IUUC-Psi-093541	Pelodiscus sinensis	91.23	0.00e+00	1115.00
IUUC-Pma-094108	Petromyzon marinus	56.22	3.00e-153	535.00
IUUC-Pfo-097119	Poecilia formosa	71.97	0.00e+00	853.00
IUUC-Pab-097724	Pongo abelii	95.04	0.00e+00	1156.00
IUUC-Pca-100645	Procavia capensis	76.37	0.00e+00	720.00
IUUC-Pva-102322	Pteropus vampyrus	98.82	0.00e+00	1202.00
IUUC-Pgr-103429	Puccinia graminis	27.39	6.00e-05	43.10
IUUC-Rno-105148	Rattus norvegicus	97.01	0.00e+00	1206.00
IUUC-Sha-106673	Sarcophilus harrisii	88.34	0.00e+00	1081.00
IUUC-Ssl-108385	Sclerotinia sclerotiorum	30.95	1.00e-08	53.50
IUUC-Sar-113746	Sorex araneus	76.55	1.00e-97	350.00
IUUC-Ssc-116425	Sus scrofa	98.51	0.00e+00	1221.00
IUUC-Tgu-116520	Taeniopygia guttata	89.07	0.00e+00	1103.00
IUUC-Tru-117750	Takifugu rubripes	67.04	0.00e+00	840.00
IUUC-Tsy-118975	Tarsius syrichta	97.31	0.00e+00	1164.00
IUUC-Tni-119830	Tetraodon nigroviridis	72.47	0.00e+00	863.00
IUUC-Ttr-129103	Tursiops truncatus	98.34	0.00e+00	1219.00
IUUC-Vpa-130720	Vicugna pacos	99.49	8.00e-115	407.00
IUUC-Xtr-132314	Xenopus tropicalis	84.30	0.00e+00	1053.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence