iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oru-084618

Ensembl Protein ID

ORUFI01G12140.1

UniProt Accession

A0A0E0MUL4; A0A0E0MUL4_ORYRU

Protein Name

Presenilin

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ORUFI01G12140	ORUFI01G12140.1	ORUFI01G12140.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/CUE	56.52	9.00e-23	104.00	IUUC-Cel-018553
UBD/Alpha-Helix/CUE	31.30	1.00e-25	115.00	IUUC-Dre-028689

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryza rufipogon

Functional Description
(View)

Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.

Protein Sequence
(Fasta)

MALVVLLISL LAPPSAPGSA AAAAQPPPPV TAATLVYLES PTDTPGQKLV GALLDAAVFV 60
ALVAVVTFVL VALYYYRCTG FLKNYMRFSA FFVLFSMGGA IAAAVLRRLG APLDAATALV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCTGG TCGTGCTCCT CATCTCCCTC CTCGCGCCGC CCTCCGCTCC GGGGTCCGCC 60
GCGGCCGCCG CGCAGCCGCC GCCGCCGGTC ACCGCCGCGA CGCTCGTCTA CCTCGAGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0378--Hydrolase
KW-0472--Membrane
KW-0914--Notch signaling pathway
KW-0645--Protease
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001108--Peptidase_A22A
IPR006639--Preselin/SPP

Pfam

PF01080--Presenilin

PRINTS

PR01072--PRESENILIN

SMART

SM00730--PSN

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0005798--C:Golgi-associated vesicle
GO:0016021--C:integral component of membrane
GO:0004190--F:aspartic-type endopeptidase activity
GO:0007219--P:Notch signaling pathway
GO:0016485--P:protein processing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000686	Aegilops tauschii	78.37	9.00e-121	427.00
IUUC-Aml-002356	Ailuropoda melanoleuca	41.12	9.00e-19	87.80
IUUC-Atr-003039	Amborella trichopoda	54.85	7.00e-101	360.00
IUUC-Apl-003727	Anas platyrhynchos	32.48	3.00e-32	132.00
IUUC-Aca-004582	Anolis carolinensis	33.33	6.00e-33	134.00
IUUC-Aly-005455	Arabidopsis lyrata	52.04	1.00e-94	339.00
IUUC-Ath-006730	Arabidopsis thaliana	51.91	2.00e-94	338.00
IUUC-Ame-010686	Astyanax mexicanus	34.71	3.00e-26	112.00
IUUC-Bta-013026	Bos taurus	32.00	2.00e-31	129.00
IUUC-Bdi-014196	Brachypodium distachyon	80.89	4.00e-151	527.00
IUUC-Bol-015841	Brassica oleracea	54.35	4.00e-90	324.00
IUUC-Bra-017580	Brassica rapa	52.05	4.00e-82	297.00
IUUC-Cel-018553	Caenorhabditis elegans	33.64	2.00e-40	159.00
IUUC-Cja-018824	Callithrix jacchus	38.01	2.00e-25	109.00
IUUC-Cfa-020074	Canis familiaris	33.59	3.00e-34	139.00
IUUC-Cpo-022237	Cavia porcellus	34.36	7.00e-33	134.00
IUUC-Cre-022747	Chlamydomonas reinhardtii	44.20	6.00e-35	141.00
IUUC-Csa-023537	Chlorocebus sabaeus	35.13	3.00e-34	139.00
IUUC-Cho-024735	Choloepus hoffmanni	33.43	3.00e-29	122.00
IUUC-Cin-025780	Ciona intestinalis	33.08	7.00e-38	150.00
IUUC-Csv-025967	Ciona savignyi	38.62	3.00e-22	99.00
IUUC-Dre-028689	Danio rerio	33.33	2.00e-29	123.00
IUUC-Dno-029758	Dasypus novemcinctus	34.87	1.00e-34	140.00
IUUC-Dor-030609	Dipodomys ordii	55.56	8.00e-19	87.80
IUUC-Dme-031929	Drosophila melanogaster	37.72	5.00e-24	105.00
IUUC-Ete-032487	Echinops telfairi	35.97	1.00e-14	73.90
IUUC-Eca-034387	Equus caballus	36.31	2.00e-25	109.00
IUUC-Eeu-035134	Erinaceus europaeus	34.56	1.00e-31	129.00
IUUC-Fca-036243	Felis catus	33.59	1.00e-33	136.00
IUUC-Fal-036600	Ficedula albicollis	32.56	1.00e-32	133.00
IUUC-Gmo-038550	Gadus morhua	36.75	2.00e-25	109.00
IUUC-Gga-040993	Gallus gallus	33.08	2.00e-34	139.00
IUUC-Gac-042511	Gasterosteus aculeatus	33.58	1.00e-32	133.00
IUUC-Gma-043822	Glycine max	85.88	1.00e-39	156.00
IUUC-Ggo-045338	Gorilla gorilla	37.43	5.00e-26	111.00
IUUC-Hsa-046822	Homo sapiens	35.13	3.00e-34	139.00
IUUC-Hvu-047141	Hordeum vulgare	79.40	3.00e-130	457.00
IUUC-Itr-048420	Ictidomys tridecemlineatus	33.42	1.00e-33	136.00
IUUC-Lch-049638	Latimeria chalumnae	34.64	2.00e-24	106.00
IUUC-Lpe-051132	Leersia perrieri	89.05	7.00e-167	579.00
IUUC-Loc-052427	Lepisosteus oculatus	31.58	1.00e-34	140.00
IUUC-Laf-053979	Loxodonta africana	33.25	1.00e-30	126.00
IUUC-Mcc-055682	Macaca mulatta	35.13	3.00e-34	139.00
IUUC-Meu-056004	Macropus eugenii	29.71	3.00e-20	92.40
IUUC-Mtr-058392	Medicago truncatula	53.75	3.00e-95	341.00
IUUC-Mga-059466	Meleagris gallopavo	33.25	3.00e-34	139.00
IUUC-Mmr-060890	Microcebus murinus	36.31	4.00e-25	108.00
IUUC-Mdo-062122	Monodelphis domestica	33.93	1.00e-32	134.00
IUUC-Mmu-063823	Mus musculus	36.87	1.00e-25	110.00
IUUC-Mac-064858	Musa acuminata	67.65	1.00e-45	176.00
IUUC-Mpu-065927	Mustela putorius furo	33.85	1.00e-34	140.00
IUUC-Mlu-067079	Myotis lucifugus	33.85	4.00e-37	148.00
IUUC-Nle-070180	Nomascus leucogenys	35.13	3.00e-34	139.00
IUUC-Opr-070344	Ochotona princeps	35.20	6.00e-23	101.00
IUUC-Ont-071846	Oreochromis niloticus	32.75	2.00e-30	125.00
IUUC-Oan-072783	Ornithorhynchus anatinus	33.74	1.00e-28	119.00
IUUC-Ocu-074527	Oryctolagus cuniculus	33.33	3.00e-33	135.00
IUUC-Oba-075256	Oryza barthii	99.72	3.00e-168	583.00
IUUC-Obr-076302	Oryza brachyantha	87.98	2.00e-167	581.00
IUUC-Ogl-077097	Oryza glaberrima	99.75	1.00e-180	625.00
IUUC-Ogu-078570	Oryza glumaepatula	99.50	4.00e-180	623.00
IUUC-Oin-079244	Oryza indica	99.75	2.00e-180	624.00
IUUC-Olo-080484	Oryza longistaminata	97.59	6.00e-130	456.00
IUUC-Ome-081814	Oryza meridionalis	97.01	1.00e-178	618.00
IUUC-Oni-082057	Oryza nivara	99.75	3.00e-180	623.00
IUUC-Opu-084176	Oryza punctata	96.00	2.00e-178	617.00
IUUC-Osa-085602	Oryza sativa	99.75	0.00e+00	629.00
IUUC-Ola-086707	Oryzias latipes	35.03	1.00e-25	109.00
IUUC-Olu-087811	Ostreococcus lucimarinus	34.77	5.00e-44	171.00
IUUC-Oga-088560	Otolemur garnettii	36.31	2.00e-25	109.00
IUUC-Oar-090348	Ovis aries	33.08	6.00e-36	144.00
IUUC-Ptr-091060	Pan troglodytes	35.13	3.00e-34	139.00
IUUC-Pan-091742	Papio anubis	37.43	4.00e-26	112.00
IUUC-Psi-093505	Pelodiscus sinensis	33.33	1.00e-33	137.00
IUUC-Pma-094612	Petromyzon marinus	31.22	3.00e-21	95.90
IUUC-Ppa-095431	Physcomitrella patens	44.70	6.00e-85	307.00
IUUC-Pfo-097396	Poecilia formosa	32.26	4.00e-36	145.00
IUUC-Pab-098591	Pongo abelii	35.13	3.00e-34	139.00
IUUC-Pop-099661	Populus trichocarpa	47.50	4.00e-76	277.00
IUUC-Pca-101120	Procavia capensis	34.08	1.00e-21	97.10
IUUC-Ppe-101495	Prunus persica	53.36	2.00e-99	355.00
IUUC-Pva-102934	Pteropus vampyrus	34.08	2.00e-23	103.00
IUUC-Rno-106052	Rattus norvegicus	36.31	2.00e-25	109.00
IUUC-Sha-107045	Sarcophilus harrisii	32.91	3.00e-33	135.00
IUUC-Smo-109325	Selaginella moellendorffii	43.42	8.00e-58	216.00
IUUC-Sit-110624	Setaria italica	82.57	3.00e-142	497.00
IUUC-Sly-110865	Solanum lycopersicum	85.92	2.00e-32	130.00
IUUC-Stu-112433	Solanum tuberosum	53.28	3.00e-91	328.00
IUUC-Sar-113169	Sorex araneus	40.19	1.00e-18	87.40
IUUC-Sbi-114305	Sorghum bicolor	81.86	2.00e-145	508.00
IUUC-Ssc-115766	Sus scrofa	33.33	2.00e-32	132.00
IUUC-Tgu-116469	Taeniopygia guttata	31.84	6.00e-30	124.00
IUUC-Tru-117732	Takifugu rubripes	31.83	1.00e-31	130.00
IUUC-Tsy-119624	Tarsius syrichta	34.71	4.00e-20	92.40
IUUC-Tni-119852	Tetraodon nigroviridis	31.28	1.00e-18	87.40
IUUC-Tca-121865	Theobroma cacao	55.29	7.00e-101	360.00
IUUC-Tae-123984	Triticum aestivum	78.61	5.00e-127	447.00
IUUC-Tur-126237	Triticum urartu	77.53	5.00e-123	433.00
IUUC-Tbe-127632	Tupaia belangeri	37.43	4.00e-26	112.00
IUUC-Ttr-128793	Tursiops truncatus	33.24	2.00e-31	129.00
IUUC-Vpa-130625	Vicugna pacos	39.05	8.00e-18	84.30
IUUC-Vvi-131312	Vitis vinifera	53.83	2.00e-97	348.00
IUUC-Xtr-132756	Xenopus tropicalis	31.67	2.00e-33	135.00
IUUC-Xma-133377	Xiphophorus maculatus	32.08	2.00e-34	139.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence