iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010599

Ensembl Protein ID

ENSAMXP00000003396.1

UniProt Accession

W5K735; W5K735_ASTMX

Genbank Protein ID

ENSAMXP00000003396

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01120063

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000003321.1	ENSAMXT00000003396.1	ENSAMXP00000003396.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.20e-37	124.1	436	473
UBD/Beta-Prp	1.00e-63	215.6	276	562

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH ++v c++f ++ +++++Gs D+t+++W++ +g+++
   Q: 436  GHLADVDCVKFhPNsNYIATGSTDKTVRLWSTQQGNSV 473
           899*********777****************9999876 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfsp 62
           ++h ++ ++   +spd++lla+g++++ +k+w+++  kl                                +++l gh ++v+ + f  
   Q: 276  FQHTEQLLNTAEVSPDSRLLAAGFDNSAVKLWSLRARKLkagphkadvakirlacdvleeeadeedasgseIKTLRGHCGPVYRTAFLT 364
           567777888899***************************************************************************** PP
   S: 63   dgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnl 151
           d++ l+++seD t++ wdl++++ v  ++gh + v+++++sp + ++ ++s+drt+r+w  +  + l+ + +gh + v cv++hp++n+
   Q: 365  DSSGLLSCSEDSTVRYWDLNSFTNVALYRGHAYPVWDVDVSPCSLYFCTASQDRTARLWTFQRTYPLR-LYAGHLADVDCVKFHPNSNY 452
           ********************************************************************.******************** PP
   S: 152  lvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsg 240
           +++Gs+D+tvrlW+ ++g+ +r +tg h ++v sl+f++ngk+l+s+++d++vklwdl +g+  + l+ghtd v s+ fsp++ +++s+
   Q: 453  IATGSTDKTVRLWSTQQGNSVRLFTG-HRGPVLSLAFSPNGKYLASAGEDQRVKLWDLASGTLFKDLRGHTDSVMSLSFSPDSALVASA 540
           *************************9.************************************************************** PP
   S: 241  ssDgsiriWdlrsgdllktlql 262
           + D+s+r+Wd+r+     + + 
   Q: 541  ALDNSVRVWDIRNAHSGAAAAA 562
           *********7776655444433 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MKRGRTEQIQ YAVTQYLKRR QYVDTDGSLK GAKLSQSAEE MAASLTVQTE SSCANVVSAA 60
PCQSDPQQYD AQFSKLRTFL LEAEVPWASE VSVVLFPLFL YLHLDMARCG LKGAVDSFYS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAGCGCTTT TTATTCCGAA TTCACTCCGA ATTATTACTG TTTCTGAGTG AAAGGCGGTG 60
GGAGAGATAT GCAGTGAGTA TTAAGCTCGT TATTACCGCG GGTTTAGCGG TTTAGAATAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR007582--TFIID_NTD2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	67.22	0.00e+00	786.00
IUUC-Apl-003636	Anas platyrhynchos	68.15	0.00e+00	843.00
IUUC-Aca-004229	Anolis carolinensis	67.22	0.00e+00	811.00
IUUC-Bta-013404	Bos taurus	66.67	0.00e+00	768.00
IUUC-Cja-019643	Callithrix jacchus	67.05	0.00e+00	796.00
IUUC-Cfa-020913	Canis familiaris	67.05	0.00e+00	795.00
IUUC-Cpo-021777	Cavia porcellus	66.89	0.00e+00	785.00
IUUC-Csa-024184	Chlorocebus sabaeus	66.72	0.00e+00	795.00
IUUC-Cho-024638	Choloepus hoffmanni	66.72	0.00e+00	783.00
IUUC-Cin-025618	Ciona intestinalis	33.93	6.00e-86	311.00
IUUC-Csv-025874	Ciona savignyi	42.05	5.00e-72	265.00
IUUC-Dre-028817	Danio rerio	85.41	0.00e+00	973.00
IUUC-Dno-029969	Dasypus novemcinctus	66.23	0.00e+00	774.00
IUUC-Dor-031117	Dipodomys ordii	67.22	0.00e+00	808.00
IUUC-Ete-032712	Echinops telfairi	61.92	0.00e+00	715.00
IUUC-Eca-033742	Equus caballus	67.05	0.00e+00	793.00
IUUC-Eeu-035096	Erinaceus europaeus	66.12	0.00e+00	808.00
IUUC-Fca-035769	Felis catus	67.00	0.00e+00	813.00
IUUC-Fal-036645	Ficedula albicollis	68.59	0.00e+00	803.00
IUUC-Gmo-038636	Gadus morhua	76.99	0.00e+00	857.00
IUUC-Gga-040144	Gallus gallus	68.21	0.00e+00	822.00
IUUC-Gac-041716	Gasterosteus aculeatus	79.80	0.00e+00	883.00
IUUC-Ggo-044568	Gorilla gorilla	66.89	0.00e+00	795.00
IUUC-Hsa-046178	Homo sapiens	66.89	0.00e+00	795.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	67.60	0.00e+00	817.00
IUUC-Lch-050501	Latimeria chalumnae	63.04	0.00e+00	712.00
IUUC-Loc-052895	Lepisosteus oculatus	80.21	5.00e-175	607.00
IUUC-Laf-053950	Loxodonta africana	65.07	0.00e+00	769.00
IUUC-Mcc-055450	Macaca mulatta	66.89	0.00e+00	795.00
IUUC-Meu-056182	Macropus eugenii	64.07	0.00e+00	752.00
IUUC-Mga-059619	Meleagris gallopavo	68.21	0.00e+00	823.00
IUUC-Mmr-061074	Microcebus murinus	67.33	0.00e+00	798.00
IUUC-Mdo-062307	Monodelphis domestica	66.46	0.00e+00	670.00
IUUC-Mmu-063226	Mus musculus	66.72	0.00e+00	780.00
IUUC-Mpu-066016	Mustela putorius furo	67.22	0.00e+00	788.00
IUUC-Mlu-067257	Myotis lucifugus	67.44	0.00e+00	807.00
IUUC-Nle-070139	Nomascus leucogenys	67.05	0.00e+00	797.00
IUUC-Opr-070243	Ochotona princeps	64.90	0.00e+00	780.00
IUUC-Ont-072686	Oreochromis niloticus	79.77	0.00e+00	941.00
IUUC-Oan-073670	Ornithorhynchus anatinus	67.06	0.00e+00	671.00
IUUC-Ocu-074525	Oryctolagus cuniculus	67.05	0.00e+00	801.00
IUUC-Ola-086524	Oryzias latipes	78.94	0.00e+00	938.00
IUUC-Oga-088540	Otolemur garnettii	66.89	0.00e+00	793.00
IUUC-Oar-089793	Ovis aries	63.74	0.00e+00	709.00
IUUC-Ptr-091154	Pan troglodytes	66.89	0.00e+00	795.00
IUUC-Pan-092759	Papio anubis	66.89	0.00e+00	795.00
IUUC-Psi-094008	Pelodiscus sinensis	65.73	0.00e+00	804.00
IUUC-Pma-094593	Petromyzon marinus	46.98	2.00e-130	459.00
IUUC-Pfo-097409	Poecilia formosa	76.58	0.00e+00	876.00
IUUC-Pab-097946	Pongo abelii	60.73	0.00e+00	678.00
IUUC-Pca-100727	Procavia capensis	62.75	0.00e+00	716.00
IUUC-Pva-103211	Pteropus vampyrus	65.40	0.00e+00	764.00
IUUC-Rno-105236	Rattus norvegicus	66.39	0.00e+00	771.00
IUUC-Sha-106833	Sarcophilus harrisii	67.71	0.00e+00	811.00
IUUC-Sar-113381	Sorex araneus	67.55	0.00e+00	822.00
IUUC-Ssc-116421	Sus scrofa	67.05	0.00e+00	821.00
IUUC-Tgu-117143	Taeniopygia guttata	67.72	0.00e+00	841.00
IUUC-Tru-118680	Takifugu rubripes	77.61	0.00e+00	920.00
IUUC-Tsy-119622	Tarsius syrichta	56.22	7.00e-168	583.00
IUUC-Tni-120131	Tetraodon nigroviridis	77.94	0.00e+00	931.00
IUUC-Ttr-129171	Tursiops truncatus	67.05	0.00e+00	780.00
IUUC-Xtr-132241	Xenopus tropicalis	66.72	0.00e+00	790.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence