iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004518

UUCD1 version

UUC-AnC-01014

Ensembl Protein ID

ENSACAP00000005901.2

UniProt Accession

H9GAV3; H9GAV3_ANOCA

Protein Name

Uncharacterized protein

Gene Name

USP7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000005830.2	ENSACAT00000006031.2	ENSACAP00000005901.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.60e-68	229.1	203	509

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN+g+tCYmNS+LQ+L+++++lr+++    + +      +++++++  +lq++f el ++++k v +++l+k++++e   +++++q
   Q: 203  VGLKNQGATCYMNSLLQTLFFTNQLRKAVYM-MPTEG-----DDSSKSVPLALQRVFYEL-QHSDKPVGTKKLTKSFGWET--LDSFMQ 282
           6******************************.44433.....466889************.88889************887..67**** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++lld++e+++                          k +  + +i +lF+g++ s i+c++ d +s+r e+ +d++l+++g
   Q: 283  HDVQELCRVLLDNVENKM--------------------------KGTCVEGTIPKLFRGKMVSYIQCKHVDYRSERIEDYYDIQLSIKG 345
           ******************..........................789****************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
           k+     ++ +++ ++++ e+l+g+nky   +  ++qeaek +k+ +lP+vL+l+L+Rf ++ ++++++kin+++efp++L l++f+++
   Q: 346  KK-----NIFESFIDYVAVEQLDGDNKYDAGEH-GLQEAEKGVKFITLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPDQLPLDEFLQK 428
           **.....9*********************9996.7****************************************************** PP
   S: 268  peekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg............staYvlfYkr 337
           ++ k+    +Y L+av+vHsG  ++GHYv+y +   +gkW++fdD+ V+ +++ee  e +             ++aY+l+Y r
   Q: 429  TDPKD--AANYILHAVLVHSGDNHGGHYVVYLNPkGDGKWCKFDDDVVSRCTKEEAIEHNYgghdddlsvrhcTNAYMLVYIR 509
           88777..9************************9834566************86666664446*******************87 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MVCLLFPLTS PAGDADDPPR ITQNPVINGN VAMADGHNNT EEDMEDDTSW RSEATFQFTV 60
ERFNRLSESV LSPPCFVRNL PWKIMVMPRL YPDRPHQKSV GFFLQCNAES SVSAFWSEMT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGTGTC TCCTGTTCCC CTTGACTTCA CCAGCTGGAG ATGCTGATGA TCCACCAAGA 60
ATTACTCAAA ATCCAGTCAT CAATGGGAAT GTGGCAATGG CTGACGGCCA CAACAACACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002083--MATH/TRAF_dom
IPR001394--Peptidase_C19_UCH
IPR008974--TRAF-like
IPR024729--USP7_ICP0-binding_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50144--MATH
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF14533--USP7_C2
PF12436--USP7_ICP0_bdg

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0010216--P:maintenance of DNA methylation
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0050821--P:protein stabilization
GO:0006283--P:transcription-coupled nucleotide-excision repair
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000761	Aegilops tauschii	34.37	1.00e-129	457.00
IUUC-Aml-002408	Ailuropoda melanoleuca	91.09	0.00e+00	2037.00
IUUC-Atr-003067	Amborella trichopoda	37.39	4.00e-126	445.00
IUUC-Apl-003558	Anas platyrhynchos	92.55	0.00e+00	2081.00
IUUC-Aly-006453	Arabidopsis lyrata	38.45	2.00e-147	516.00
IUUC-Ath-006591	Arabidopsis thaliana	37.58	2.00e-144	506.00
IUUC-Ago-007849	Ashbya gossypii	31.64	6.00e-129	455.00
IUUC-Acl-008327	Aspergillus clavatus	33.76	3.00e-165	576.00
IUUC-Afl-008491	Aspergillus flavus	34.31	2.00e-157	550.00
IUUC-Afu-008804	Aspergillus fumigatus	34.25	1.00e-153	537.00
IUUC-Ang-009776	Aspergillus niger	33.59	3.00e-154	539.00
IUUC-Aor-009998	Aspergillus oryzae	33.58	6.00e-149	521.00
IUUC-Ate-010428	Aspergillus terreus	34.01	4.00e-157	548.00
IUUC-Ame-010903	Astyanax mexicanus	88.37	0.00e+00	1996.00
IUUC-Bgr-012132	Blumeria graminis	33.91	3.00e-140	493.00
IUUC-Bta-013192	Bos taurus	90.65	0.00e+00	2030.00
IUUC-Bci-013924	Botrytis cinerea	33.46	4.00e-147	515.00
IUUC-Bdi-015069	Brachypodium distachyon	35.59	2.00e-141	497.00
IUUC-Bol-015224	Brassica oleracea	35.79	2.00e-144	506.00
IUUC-Bra-017448	Brassica rapa	35.76	3.00e-144	506.00
IUUC-Cel-018219	Caenorhabditis elegans	33.01	3.00e-141	496.00
IUUC-Cja-019006	Callithrix jacchus	89.83	0.00e+00	2003.00
IUUC-Cfa-020361	Canis familiaris	91.18	0.00e+00	2038.00
IUUC-Cpo-022320	Cavia porcellus	91.15	0.00e+00	2030.00
IUUC-Cre-022708	Chlamydomonas reinhardtii	47.21	3.00e-84	305.00
IUUC-Csa-024050	Chlorocebus sabaeus	91.24	0.00e+00	2037.00
IUUC-Cho-024434	Choloepus hoffmanni	87.15	0.00e+00	1393.00
IUUC-Cin-025689	Ciona intestinalis	52.41	0.00e+00	1135.00
IUUC-Csv-025963	Ciona savignyi	51.08	0.00e+00	1081.00
IUUC-Cgl-026650	Colletotrichum gloeosporioides	33.30	4.00e-147	515.00
IUUC-Cne-026968	Cryptococcus neoformans	36.06	6.00e-176	611.00
IUUC-Cme-027103	Cyanidioschyzon merolae	35.83	6.00e-106	379.00
IUUC-Dre-028510	Danio rerio	88.64	0.00e+00	1997.00
IUUC-Dno-029696	Dasypus novemcinctus	90.73	0.00e+00	2024.00
IUUC-Dor-030611	Dipodomys ordii	72.36	0.00e+00	815.00
IUUC-Dse-031433	Dothistroma septosporum	35.85	2.00e-137	483.00
IUUC-Dme-031583	Drosophila melanogaster	46.65	0.00e+00	966.00
IUUC-Ete-033191	Echinops telfairi	88.89	0.00e+00	1985.00
IUUC-Eca-034122	Equus caballus	90.82	0.00e+00	2031.00
IUUC-Eeu-035292	Erinaceus europaeus	69.29	6.00e-154	538.00
IUUC-Fca-036377	Felis catus	91.09	0.00e+00	2038.00
IUUC-Fal-036964	Ficedula albicollis	92.48	0.00e+00	2040.00
IUUC-Fox-037695	Fusarium oxysporum	32.97	2.00e-150	526.00
IUUC-Fso-038084	Fusarium solani	33.21	3.00e-153	536.00
IUUC-Gmo-038644	Gadus morhua	88.20	0.00e+00	1993.00
IUUC-Ggr-040029	Gaeumannomyces graminis	32.74	1.00e-149	524.00
IUUC-Gga-040944	Gallus gallus	92.67	0.00e+00	2071.00
IUUC-Gac-041740	Gasterosteus aculeatus	88.66	0.00e+00	1998.00
IUUC-Gma-043300	Glycine max	35.73	3.00e-157	549.00
IUUC-Ggo-044947	Gorilla gorilla	91.15	0.00e+00	2033.00
IUUC-Hsa-046278	Homo sapiens	91.06	0.00e+00	2033.00
IUUC-Hvu-047749	Hordeum vulgare	38.60	3.00e-127	449.00
IUUC-Itr-047904	Ictidomys tridecemlineatus	95.89	0.00e+00	1831.00
IUUC-Kpa-049121	Komagataella pastoris	30.65	1.00e-121	431.00
IUUC-Lch-049847	Latimeria chalumnae	91.34	0.00e+00	2051.00
IUUC-Lpe-051543	Leersia perrieri	36.95	2.00e-139	489.00
IUUC-Loc-052234	Lepisosteus oculatus	86.64	0.00e+00	1296.00
IUUC-Lma-053169	Leptosphaeria maculans	38.37	7.00e-161	561.00
IUUC-Laf-053566	Loxodonta africana	91.34	0.00e+00	2034.00
IUUC-Mcc-055549	Macaca mulatta	91.15	0.00e+00	2029.00
IUUC-Meu-056887	Macropus eugenii	86.91	0.00e+00	1261.00
IUUC-Mor-057149	Magnaporthe oryzae	33.75	8.00e-152	531.00
IUUC-Mpo-057536	Magnaporthe poae	33.15	2.00e-150	526.00
IUUC-Mtr-058583	Medicago truncatula	36.78	2.00e-151	530.00
IUUC-Mla-058899	Melampsora laricipopulina	38.91	2.00e-164	573.00
IUUC-Mga-060148	Meleagris gallopavo	92.72	0.00e+00	2088.00
IUUC-Mvi-060207	Microbotryum violaceum	37.33	3.00e-172	598.00
IUUC-Mmr-060946	Microcebus murinus	91.43	0.00e+00	2040.00
IUUC-Mdo-062079	Monodelphis domestica	86.51	0.00e+00	1885.00
IUUC-Mmu-063678	Mus musculus	90.78	0.00e+00	2024.00
IUUC-Mac-065416	Musa acuminata	36.26	3.00e-143	502.00
IUUC-Mpu-066744	Mustela putorius furo	91.17	0.00e+00	1991.00
IUUC-Mlu-067949	Myotis lucifugus	90.54	0.00e+00	2014.00
IUUC-Nfi-068342	Neosartorya fischeri	34.25	5.00e-154	538.00
IUUC-Ncr-068818	Neurospora crassa	34.00	1.00e-153	537.00
IUUC-Nle-070064	Nomascus leucogenys	91.15	0.00e+00	2035.00
IUUC-Opr-071001	Ochotona princeps	89.26	0.00e+00	1665.00
IUUC-Ont-072095	Oreochromis niloticus	88.55	0.00e+00	1998.00
IUUC-Oan-073483	Ornithorhynchus anatinus	91.92	0.00e+00	2001.00
IUUC-Ocu-073967	Oryctolagus cuniculus	90.42	0.00e+00	1951.00
IUUC-Oba-075312	Oryza barthii	33.99	4.00e-129	456.00
IUUC-Obr-076857	Oryza brachyantha	35.08	2.00e-141	496.00
IUUC-Ogl-077038	Oryza glaberrima	34.77	3.00e-138	486.00
IUUC-Ogu-078265	Oryza glumaepatula	33.18	3.00e-124	439.00
IUUC-Oin-079513	Oryza indica	37.15	1.00e-129	457.00
IUUC-Olo-081067	Oryza longistaminata	35.94	5.00e-127	448.00
IUUC-Ome-081879	Oryza meridionalis	38.31	5.00e-140	491.00
IUUC-Oni-082461	Oryza nivara	36.82	6.00e-136	478.00
IUUC-Opu-083199	Oryza punctata	37.57	2.00e-134	473.00
IUUC-Oru-085109	Oryza rufipogon	37.71	2.00e-135	476.00
IUUC-Osa-085418	Oryza sativa	37.73	2.00e-116	413.00
IUUC-Ola-086640	Oryzias latipes	88.66	0.00e+00	1991.00
IUUC-Olu-087874	Ostreococcus lucimarinus	34.02	2.00e-135	476.00
IUUC-Oga-089059	Otolemur garnettii	84.08	0.00e+00	1844.00
IUUC-Oar-089710	Ovis aries	90.59	0.00e+00	2030.00
IUUC-Ptr-091334	Pan troglodytes	91.15	0.00e+00	2033.00
IUUC-Pan-091717	Papio anubis	91.26	0.00e+00	1971.00
IUUC-Psi-093933	Pelodiscus sinensis	92.66	0.00e+00	2088.00
IUUC-Pma-094648	Petromyzon marinus	78.61	0.00e+00	1625.00
IUUC-Pno-095020	Phaeosphaeria nodorum	36.72	1.00e-143	503.00
IUUC-Ppa-095922	Physcomitrella patens	37.69	3.00e-147	516.00
IUUC-Pfo-096181	Poecilia formosa	88.37	0.00e+00	1995.00
IUUC-Pab-098231	Pongo abelii	88.66	0.00e+00	1961.00
IUUC-Pop-099680	Populus trichocarpa	36.24	3.00e-149	522.00
IUUC-Pca-100543	Procavia capensis	72.74	0.00e+00	892.00
IUUC-Ppe-101523	Prunus persica	37.78	7.00e-144	504.00
IUUC-Pva-102472	Pteropus vampyrus	89.90	0.00e+00	1986.00
IUUC-Pgr-103463	Puccinia graminis	36.90	1.00e-164	573.00
IUUC-Ptt-103716	Puccinia triticina	38.49	2.00e-162	566.00
IUUC-Pte-104360	Pyrenophora teres	38.10	4.00e-148	519.00
IUUC-Pyt-104581	Pyrenophora triticirepentis	37.68	2.00e-146	513.00
IUUC-Rno-105816	Rattus norvegicus	90.78	0.00e+00	2028.00
IUUC-Sce-106230	Saccharomyces cerevisiae	29.00	4.00e-112	399.00
IUUC-Sha-107439	Sarcophilus harrisii	92.07	0.00e+00	2043.00
IUUC-Sja-107690	Schizosaccharomyces japonicus	31.77	4.00e-134	472.00
IUUC-Spo-108019	Schizosaccharomyces pombe	34.14	4.00e-137	482.00
IUUC-Smo-109308	Selaginella moellendorffii	37.87	3.00e-142	499.00
IUUC-Sit-110367	Setaria italica	35.33	7.00e-146	511.00
IUUC-Sly-111337	Solanum lycopersicum	36.83	6.00e-150	525.00
IUUC-Stu-112387	Solanum tuberosum	36.22	5.00e-153	535.00
IUUC-Sar-113685	Sorex araneus	90.82	0.00e+00	2024.00
IUUC-Sbi-114037	Sorghum bicolor	38.35	2.00e-145	509.00
IUUC-Sre-115156	Sporisorium reilianum	40.45	1.00e-177	617.00
IUUC-Ssc-116297	Sus scrofa	91.24	0.00e+00	2038.00
IUUC-Tgu-116767	Taeniopygia guttata	92.36	0.00e+00	2079.00
IUUC-Tru-118208	Takifugu rubripes	88.29	0.00e+00	1966.00
IUUC-Tsy-119277	Tarsius syrichta	73.95	2.00e-163	570.00
IUUC-Tni-119890	Tetraodon nigroviridis	88.39	0.00e+00	1974.00
IUUC-Tca-121501	Theobroma cacao	35.00	2.00e-147	516.00
IUUC-Tre-122169	Trichoderma reesei	33.06	1.00e-144	507.00
IUUC-Tvi-122600	Trichoderma virens	33.57	2.00e-154	540.00
IUUC-Tae-125264	Triticum aestivum	37.64	9.00e-142	498.00
IUUC-Tur-126287	Triticum urartu	36.42	3.00e-134	473.00
IUUC-Tme-127045	Tuber melanosporum	34.00	2.00e-159	556.00
IUUC-Tbe-127696	Tupaia belangeri	85.16	2.00e-155	542.00
IUUC-Ttr-129161	Tursiops truncatus	91.18	0.00e+00	2034.00
IUUC-Uma-129535	Ustilago maydis	40.10	1.00e-180	627.00
IUUC-Vda-129708	Verticillium dahliae	33.20	9.00e-153	534.00
IUUC-Vvi-131048	Vitis vinifera	35.18	5.00e-147	515.00
IUUC-Xtr-132073	Xenopus tropicalis	87.17	0.00e+00	1945.00
IUUC-Xma-133949	Xiphophorus maculatus	88.28	0.00e+00	1991.00
IUUC-Yli-134527	Yarrowia lipolytica	33.07	2.00e-133	470.00
IUUC-Zma-135855	Zea mays	37.60	1.00e-133	471.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence