iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044924

UUCD1 version

UUC-GoG-01118

Ensembl Protein ID

ENSGGOP00000014276.2

UniProt Accession

G3RFB3; G3RFB3_GORGO

Protein Name

Uncharacterized protein

Gene Name

USP34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000014575.2	ENSGGOT00000014687.2	ENSGGOP00000014276.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-69	235.6	1715	2060

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           +Gl+Nlg+tCY+ S++Q+L++ipe r+++++ k++e++       ++++ l +lqk+f+ l++s+ ka++pr + k+  + ++ +++
   Q: 1715 VGLTNLGATCYLASTIQQLYMIPEARQAVFTaKYSEDM-------KHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNT 1794
           6******************************3444444.......4568899*********************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            eq+D  Ef++ l+ ++ee                               + k++++ lF+g ++++++ l+c++vs++ e+f+++ 
   Q: 1795 GEQKDMTEFFTDLITKIEEMS----------------------------PELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVR 1853
           *****************9977............................567899******************************** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLd 260
           ++v + +     +++++L++ t +++leg+n+y c++c kk++aek+  +kklP++L+++ +R++f+  ++++ek+n++++fpl+Ld
   Q: 1854 CQVADMK-----NISESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLD 1935
           *******.....9************************************************************************** PP
   S: 261  lspfcts................peekqkekkkYeLiavvvHsGslssGHYvayvkn.......ekgkWllfdDskVtevkeeevle 324
           ++p++++                + +k++e+++Y+Li+v vH+G++++GHY++++++       +++kW+lf+D +V++ + ++  +
   Q: 1936 MTPYTEDflmgkserkegfkevsDHSKDSESYEYDLIGVTVHTGTADGGHYYSFIRDivnphahKNNKWYLFNDAEVKPFDSAQLAS 2022
           *******99999999999999986666667***************************99999988888******************9 PP
   S: 325  etg........................staYvlfYkrr 338
           e+                         ++aY+lfYkr+
   Q: 2023 ECFggemttktydsvtdkfmdfsfektHSAYMLFYKRM 2060
           7779********************************96 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

DISTQESNIL GAFCDMNDVE VPLHLLRYVC LFCGKNGLSL MKDCFEYGTP ETLPFLIAHA 60
FITVVSNIRI WLHIPAVMQH IIPFRTYVIR YLCKLSDQEL RQSAARNMAD LMWSTVKEPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATATATCAA CTCAAGAAAG TAACATATTA GGGGCATTCT GTGATATGAA TGTAAGTGTT 60
TACCTTTTTT ATTCTTTTAT GGAAAATTTT ATTTTTTTAA CAAAGCCTCA TCCATATGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR011030--Vitellinogen_superhlx

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002257	Ailuropoda melanoleuca	94.45	0.00e+00	6261.00
IUUC-Apl-003284	Anas platyrhynchos	90.91	0.00e+00	6007.00
IUUC-Aca-004415	Anolis carolinensis	89.45	0.00e+00	5925.00
IUUC-Acl-008140	Aspergillus clavatus	28.62	2.00e-64	242.00
IUUC-Afl-008381	Aspergillus flavus	28.81	2.00e-64	242.00
IUUC-Afu-008857	Aspergillus fumigatus	27.21	4.00e-64	241.00
IUUC-Ani-009257	Aspergillus nidulans	28.68	6.00e-57	217.00
IUUC-Ang-009759	Aspergillus niger	27.72	3.00e-64	241.00
IUUC-Aor-009931	Aspergillus oryzae	28.81	2.00e-64	242.00
IUUC-Ate-010246	Aspergillus terreus	29.24	3.00e-53	205.00
IUUC-Ame-011219	Astyanax mexicanus	70.60	0.00e+00	2418.00
IUUC-Bgr-012195	Blumeria graminis	26.28	4.00e-65	244.00
IUUC-Bta-012989	Bos taurus	94.02	0.00e+00	6209.00
IUUC-Bci-013798	Botrytis cinerea	32.44	1.00e-58	223.00
IUUC-Cja-018974	Callithrix jacchus	97.41	0.00e+00	829.00
IUUC-Cfa-021214	Canis familiaris	94.54	0.00e+00	6272.00
IUUC-Cpo-021912	Cavia porcellus	93.93	0.00e+00	4234.00
IUUC-Csa-023658	Chlorocebus sabaeus	95.28	0.00e+00	6288.00
IUUC-Cho-024971	Choloepus hoffmanni	82.63	0.00e+00	3148.00
IUUC-Cgl-026466	Colletotrichum gloeosporioides	27.68	2.00e-63	239.00
IUUC-Dre-027428	Danio rerio	80.71	0.00e+00	4397.00
IUUC-Dno-029690	Dasypus novemcinctus	93.55	0.00e+00	6137.00
IUUC-Dor-030817	Dipodomys ordii	87.02	0.00e+00	2098.00
IUUC-Dse-031423	Dothistroma septosporum	25.23	4.00e-36	148.00
IUUC-Dme-032102	Drosophila melanogaster	54.24	0.00e+00	849.00
IUUC-Ete-032552	Echinops telfairi	91.24	0.00e+00	2939.00
IUUC-Eca-033457	Equus caballus	94.36	0.00e+00	6251.00
IUUC-Eeu-035118	Erinaceus europaeus	91.54	0.00e+00	3012.00
IUUC-Fca-036213	Felis catus	91.33	0.00e+00	4815.00
IUUC-Fal-037643	Ficedula albicollis	88.78	0.00e+00	5877.00
IUUC-Fox-037971	Fusarium oxysporum	27.27	2.00e-63	238.00
IUUC-Fso-038108	Fusarium solani	26.94	9.00e-60	226.00
IUUC-Ggr-040075	Gaeumannomyces graminis	32.63	3.00e-63	238.00
IUUC-Gga-040511	Gallus gallus	88.79	0.00e+00	5912.00
IUUC-Gac-042024	Gasterosteus aculeatus	84.15	0.00e+00	4776.00
IUUC-Hsa-046913	Homo sapiens	95.58	0.00e+00	6335.00
IUUC-Itr-048626	Ictidomys tridecemlineatus	94.20	0.00e+00	6259.00
IUUC-Lch-049675	Latimeria chalumnae	83.12	0.00e+00	4462.00
IUUC-Loc-052832	Lepisosteus oculatus	83.91	0.00e+00	5504.00
IUUC-Lma-053130	Leptosphaeria maculans	27.49	5.00e-61	231.00
IUUC-Laf-054169	Loxodonta africana	92.84	0.00e+00	6199.00
IUUC-Mcc-055847	Macaca mulatta	94.39	0.00e+00	6198.00
IUUC-Meu-056327	Macropus eugenii	81.54	0.00e+00	1509.00
IUUC-Mor-057152	Magnaporthe oryzae	35.14	2.00e-62	235.00
IUUC-Mpo-057310	Magnaporthe poae	26.97	8.00e-63	236.00
IUUC-Mmr-060780	Microcebus murinus	94.66	0.00e+00	6274.00
IUUC-Mdo-062308	Monodelphis domestica	89.29	0.00e+00	5921.00
IUUC-Mmu-063457	Mus musculus	92.48	0.00e+00	6154.00
IUUC-Mpu-066917	Mustela putorius furo	93.00	0.00e+00	6134.00
IUUC-Mlu-067696	Myotis lucifugus	94.06	0.00e+00	6227.00
IUUC-Nfi-068259	Neosartorya fischeri	27.21	1.00e-64	243.00
IUUC-Ncr-068911	Neurospora crassa	25.81	1.00e-59	226.00
IUUC-Nle-069586	Nomascus leucogenys	95.31	0.00e+00	6345.00
IUUC-Opr-070447	Ochotona princeps	91.25	0.00e+00	2829.00
IUUC-Ont-072396	Oreochromis niloticus	82.36	0.00e+00	5087.00
IUUC-Oan-073147	Ornithorhynchus anatinus	91.15	0.00e+00	6071.00
IUUC-Ocu-074324	Oryctolagus cuniculus	94.15	0.00e+00	6227.00
IUUC-Ola-086312	Oryzias latipes	78.58	0.00e+00	5013.00
IUUC-Oga-088878	Otolemur garnettii	94.69	0.00e+00	6286.00
IUUC-Oar-089919	Ovis aries	94.05	0.00e+00	6208.00
IUUC-Ptr-090713	Pan troglodytes	94.97	0.00e+00	5753.00
IUUC-Pan-091957	Papio anubis	94.50	0.00e+00	4907.00
IUUC-Psi-093240	Pelodiscus sinensis	90.13	0.00e+00	5980.00
IUUC-Pma-094469	Petromyzon marinus	69.87	0.00e+00	3920.00
IUUC-Pno-095059	Phaeosphaeria nodorum	29.57	6.00e-58	220.00
IUUC-Pfo-097159	Poecilia formosa	80.32	0.00e+00	5126.00
IUUC-Pab-098003	Pongo abelii	95.29	0.00e+00	6282.00
IUUC-Pca-100799	Procavia capensis	89.63	0.00e+00	1938.00
IUUC-Pva-103226	Pteropus vampyrus	89.23	0.00e+00	5827.00
IUUC-Pte-104235	Pyrenophora teres	26.84	1.00e-59	226.00
IUUC-Pyt-104803	Pyrenophora triticirepentis	27.33	2.00e-61	231.00
IUUC-Rno-105389	Rattus norvegicus	91.66	0.00e+00	5296.00
IUUC-Sha-106979	Sarcophilus harrisii	90.89	0.00e+00	6027.00
IUUC-Sar-113444	Sorex araneus	88.13	0.00e+00	5762.00
IUUC-Ssc-115815	Sus scrofa	93.71	0.00e+00	5149.00
IUUC-Tgu-117470	Taeniopygia guttata	89.99	0.00e+00	5940.00
IUUC-Tru-118543	Takifugu rubripes	78.58	0.00e+00	5085.00
IUUC-Tsy-119081	Tarsius syrichta	85.39	0.00e+00	4704.00
IUUC-Tni-120294	Tetraodon nigroviridis	81.90	8.00e-165	573.00
IUUC-Tre-122057	Trichoderma reesei	29.73	2.00e-62	235.00
IUUC-Tvi-122570	Trichoderma virens	35.62	5.00e-59	224.00
IUUC-Tme-127154	Tuber melanosporum	26.92	2.00e-60	228.00
IUUC-Tbe-127801	Tupaia belangeri	84.67	0.00e+00	3261.00
IUUC-Ttr-129262	Tursiops truncatus	90.03	0.00e+00	5871.00
IUUC-Vda-129686	Verticillium dahliae	27.91	4.00e-62	234.00
IUUC-Vpa-130484	Vicugna pacos	91.44	0.00e+00	5045.00
IUUC-Xtr-131769	Xenopus tropicalis	83.99	0.00e+00	5592.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence