iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sly-111547

Ensembl Protein ID

Solyc11g067200.1.1

UniProt Accession

K4D9X7; K4D9X7_SOLLC

Protein Name

Protein HIRA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Solyc11g067200.1	Solyc11g067200.1.1	Solyc11g067200.1.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.30e-23	80.9	123	159
UBD/Beta-Prp	2.90e-43	148.9	11	208

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gHt++v +l++ +d  +l+sGs D+ti++W+++ g +
   Q: 123  GHTADVVDLNWsPDdSTLASGSMDNTIHIWNMSNGIC 159
           8***********77799**************988766 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkl...........lrslsgheaevtavkfspdgkilvtgseDrtikvw........ 79
           h++ +i ++++ p++  +atg+ d+++++w+++   +           l++l +h + v++v++ ++g + ++gs+D++i+v         
   Q: 11   HESMQIFSIDIQPGGLRFATGGGDHKVRIWNMKCVGKdleadestpklLATLRDHFGSVNCVRWAKHGRYVASGSDDQVIQVHerkpgsgt 101
           6777888999*********************99866678999999999***********************************88888888 PP
   S: 80   .........dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtv 161
                    d+++ k ++tl+gh+++v++l++sp++++l+sGs d+ti++w++++g c+  +l+gh+++v +v+++p g+ ++s s+D+tv
   Q: 102  tefgsgeppDVENWKVTMTLRGHTADVVDLNWSPDDSTLASGSMDNTIHIWNMSNGICSA-VLRGHSSLVKGVTWDPIGSFIASQSDDKTV 191
           888888888888************************************************.****************************** PP
   S: 162  rlWdlktgkllrtltggh 179
            +W+ +  +l ++ +g h
   Q: 192  IIWRTSDWSLAHRTEG-H 208
           ****999999988877.5 PP

Organism

Solanum lycopersicum

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MIAEKPTWIR HESMQIFSID IQPGGLRFAT GGGDHKVRIW NMKCVGKDLE ADESTPKLLA 60
TLRDHFGSVN CVRWAKHGRY VASGSDDQVI QVHERKPGSG TTEFGSGEPP DVENWKVTMT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATTGCTG AGAAACCTAC TTGGATTAGA CATGAGAGTA TGCAGATTTT CTCCATTGAT 60
ATTCAGCCAG GTGGTCTTAG GTTTGCCACT GGTGGTGGTG ATCATAAGGT AACTGTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0000790--C:nuclear chromatin
GO:0031491--F:nucleosome binding
GO:0003714--F:transcription corepressor activity
GO:0016569--P:covalent chromatin modification
GO:0006336--P:DNA replication-independent nucleosome assembly
GO:0031935--P:regulation of chromatin silencing
GO:0006351--P:transcription, DNA-templated

KEGG

sly:101255760

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	65.79	0.00e+00	1350.00
IUUC-Aml-001723	Ailuropoda melanoleuca	38.04	7.00e-84	304.00
IUUC-Atr-003132	Amborella trichopoda	68.79	0.00e+00	1333.00
IUUC-Apl-003197	Anas platyrhynchos	38.06	6.00e-83	301.00
IUUC-Aca-004733	Anolis carolinensis	37.55	3.00e-86	312.00
IUUC-Aly-005446	Arabidopsis lyrata	66.77	0.00e+00	1275.00
IUUC-Ath-007627	Arabidopsis thaliana	66.94	0.00e+00	1273.00
IUUC-Ago-007766	Ashbya gossypii	30.11	5.00e-60	225.00
IUUC-Acl-008104	Aspergillus clavatus	31.11	5.00e-68	252.00
IUUC-Afl-008591	Aspergillus flavus	32.54	3.00e-67	249.00
IUUC-Afu-008781	Aspergillus fumigatus	32.99	5.00e-62	232.00
IUUC-Ani-009272	Aspergillus nidulans	27.99	2.00e-54	207.00
IUUC-Ang-009655	Aspergillus niger	32.93	5.00e-67	248.00
IUUC-Aor-010119	Aspergillus oryzae	32.54	3.00e-67	249.00
IUUC-Ate-010530	Aspergillus terreus	28.43	6.00e-53	202.00
IUUC-Bgr-012237	Blumeria graminis	33.33	1.00e-65	244.00
IUUC-Bta-013320	Bos taurus	38.60	8.00e-85	308.00
IUUC-Bci-013795	Botrytis cinerea	30.68	3.00e-70	259.00
IUUC-Bdi-014075	Brachypodium distachyon	68.89	0.00e+00	1362.00
IUUC-Bol-016440	Brassica oleracea	67.20	0.00e+00	1290.00
IUUC-Bra-016651	Brassica rapa	67.33	0.00e+00	1270.00
IUUC-Cel-018692	Caenorhabditis elegans	30.28	2.00e-48	187.00
IUUC-Cja-018987	Callithrix jacchus	37.34	2.00e-76	280.00
IUUC-Cfa-020132	Canis familiaris	38.04	7.00e-84	305.00
IUUC-Cpo-021484	Cavia porcellus	38.00	7.00e-88	318.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	35.81	2.00e-72	266.00
IUUC-Csa-023081	Chlorocebus sabaeus	38.49	1.00e-88	320.00
IUUC-Cin-025182	Ciona intestinalis	41.50	3.00e-82	299.00
IUUC-Csv-026154	Ciona savignyi	36.61	4.00e-79	289.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	25.87	3.00e-83	303.00
IUUC-Cne-026891	Cryptococcus neoformans	37.30	1.00e-80	293.00
IUUC-Cme-027349	Cyanidioschyzon merolae	28.47	4.00e-53	202.00
IUUC-Dre-027655	Danio rerio	36.95	8.00e-85	308.00
IUUC-Dno-029557	Dasypus novemcinctus	37.05	2.00e-70	259.00
IUUC-Dor-030687	Dipodomys ordii	36.73	2.00e-67	249.00
IUUC-Dse-031334	Dothistroma septosporum	32.16	5.00e-69	255.00
IUUC-Dme-031746	Drosophila melanogaster	39.85	7.00e-86	311.00
IUUC-Ete-032384	Echinops telfairi	34.08	5.00e-65	242.00
IUUC-Eca-033430	Equus caballus	38.34	7.00e-85	308.00
IUUC-Fca-036121	Felis catus	42.82	1.00e-84	307.00
IUUC-Fal-036817	Ficedula albicollis	38.45	4.00e-83	302.00
IUUC-Fox-037906	Fusarium oxysporum	34.29	1.00e-68	253.00
IUUC-Fso-038409	Fusarium solani	35.58	2.00e-67	249.00
IUUC-Gmo-039151	Gadus morhua	41.10	6.00e-83	301.00
IUUC-Ggr-040016	Gaeumannomyces graminis	34.06	6.00e-68	252.00
IUUC-Gga-040936	Gallus gallus	37.70	4.00e-87	315.00
IUUC-Gac-041405	Gasterosteus aculeatus	35.81	2.00e-79	290.00
IUUC-Gma-044252	Glycine max	72.01	0.00e+00	1493.00
IUUC-Ggo-045430	Gorilla gorilla	38.49	1.00e-88	320.00
IUUC-Hsa-046442	Homo sapiens	38.49	1.00e-88	320.00
IUUC-Hvu-047587	Hordeum vulgare	66.33	0.00e+00	1302.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	43.45	2.00e-64	238.00
IUUC-Kpa-049145	Komagataella pastoris	30.12	1.00e-53	204.00
IUUC-Lch-050474	Latimeria chalumnae	41.48	9.00e-82	298.00
IUUC-Lpe-051209	Leersia perrieri	68.20	0.00e+00	1335.00
IUUC-Loc-052119	Lepisosteus oculatus	36.00	4.00e-81	295.00
IUUC-Lma-053237	Leptosphaeria maculans	32.45	5.00e-65	242.00
IUUC-Laf-053718	Loxodonta africana	38.35	5.00e-90	325.00
IUUC-Mcc-055621	Macaca mulatta	37.17	4.00e-77	282.00
IUUC-Meu-055914	Macropus eugenii	38.89	2.00e-56	213.00
IUUC-Mor-057090	Magnaporthe oryzae	33.58	2.00e-66	247.00
IUUC-Mpo-057364	Magnaporthe poae	28.72	3.00e-85	309.00
IUUC-Mtr-057744	Medicago truncatula	75.41	0.00e+00	1471.00
IUUC-Mla-058914	Melampsora laricipopulina	34.30	7.00e-66	244.00
IUUC-Mga-060181	Meleagris gallopavo	37.55	2.00e-83	303.00
IUUC-Mvi-060432	Microbotryum violaceum	33.50	4.00e-60	225.00
IUUC-Mmr-060871	Microcebus murinus	38.69	2.00e-88	320.00
IUUC-Mdo-062301	Monodelphis domestica	38.12	3.00e-87	316.00
IUUC-Mmu-063888	Mus musculus	38.69	4.00e-89	322.00
IUUC-Mac-064768	Musa acuminata	68.82	0.00e+00	1345.00
IUUC-Mpu-066732	Mustela putorius furo	38.04	6.00e-84	305.00
IUUC-Mlu-067542	Myotis lucifugus	38.37	2.00e-86	313.00
IUUC-Nfi-068396	Neosartorya fischeri	32.99	3.00e-62	233.00
IUUC-Ncr-068842	Neurospora crassa	34.40	5.00e-68	252.00
IUUC-Nle-070156	Nomascus leucogenys	38.69	2.00e-88	320.00
IUUC-Opr-070808	Ochotona princeps	41.44	5.00e-54	205.00
IUUC-Ont-072105	Oreochromis niloticus	36.02	3.00e-81	296.00
IUUC-Ocu-074962	Oryctolagus cuniculus	38.34	1.00e-84	307.00
IUUC-Oba-075178	Oryza barthii	69.63	0.00e+00	1326.00
IUUC-Obr-076399	Oryza brachyantha	69.51	0.00e+00	1353.00
IUUC-Ogu-078797	Oryza glumaepatula	69.63	0.00e+00	1326.00
IUUC-Oin-080085	Oryza indica	69.04	0.00e+00	1249.00
IUUC-Olo-081048	Oryza longistaminata	86.75	5.00e-169	588.00
IUUC-Ome-081324	Oryza meridionalis	69.73	0.00e+00	1330.00
IUUC-Oni-082548	Oryza nivara	69.42	0.00e+00	1325.00
IUUC-Opu-084008	Oryza punctata	84.33	0.00e+00	754.00
IUUC-Oru-084339	Oryza rufipogon	69.63	0.00e+00	1327.00
IUUC-Osa-085782	Oryza sativa	69.63	0.00e+00	1327.00
IUUC-Ola-087302	Oryzias latipes	35.07	4.00e-76	279.00
IUUC-Olu-087611	Ostreococcus lucimarinus	42.13	4.00e-114	405.00
IUUC-Oga-087935	Otolemur garnettii	38.40	7.00e-86	311.00
IUUC-Oar-089229	Ovis aries	33.13	4.00e-67	249.00
IUUC-Ptr-090715	Pan troglodytes	38.49	1.00e-88	320.00
IUUC-Pan-092318	Papio anubis	38.34	1.00e-84	307.00
IUUC-Psi-094053	Pelodiscus sinensis	36.75	1.00e-81	297.00
IUUC-Pno-094985	Phaeosphaeria nodorum	30.93	2.00e-59	223.00
IUUC-Ppa-095499	Physcomitrella patens	50.00	0.00e+00	911.00
IUUC-Pfo-096857	Poecilia formosa	34.66	5.00e-78	285.00
IUUC-Pab-098047	Pongo abelii	38.49	1.00e-88	320.00
IUUC-Pop-099587	Populus trichocarpa	71.88	0.00e+00	1500.00
IUUC-Pca-100558	Procavia capensis	50.78	2.00e-50	194.00
IUUC-Ppe-101261	Prunus persica	75.57	0.00e+00	1463.00
IUUC-Pva-102683	Pteropus vampyrus	38.49	2.00e-86	313.00
IUUC-Pgr-103660	Puccinia graminis	36.10	6.00e-63	235.00
IUUC-Ptt-103900	Puccinia triticina	36.90	8.00e-63	234.00
IUUC-Pte-104209	Pyrenophora teres	33.01	2.00e-68	253.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	33.01	2.00e-67	250.00
IUUC-Rno-105566	Rattus norvegicus	38.89	2.00e-89	323.00
IUUC-Sce-106291	Saccharomyces cerevisiae	25.88	3.00e-66	246.00
IUUC-Sha-107514	Sarcophilus harrisii	35.00	1.00e-71	263.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	27.60	2.00e-90	326.00
IUUC-Spo-108162	Schizosaccharomyces pombe	35.16	3.00e-72	266.00
IUUC-Smo-109186	Selaginella moellendorffii	50.46	0.00e+00	887.00
IUUC-Sit-109980	Setaria italica	70.15	0.00e+00	1360.00
IUUC-Stu-112705	Solanum tuberosum	97.11	0.00e+00	2060.00
IUUC-Sar-113222	Sorex araneus	36.76	3.00e-78	285.00
IUUC-Sbi-114272	Sorghum bicolor	69.80	0.00e+00	1357.00
IUUC-Sre-115061	Sporisorium reilianum	34.67	3.00e-68	253.00
IUUC-Ssc-116364	Sus scrofa	38.13	8.00e-85	308.00
IUUC-Tgu-116645	Taeniopygia guttata	38.24	8.00e-83	301.00
IUUC-Tru-117590	Takifugu rubripes	36.53	3.00e-85	309.00
IUUC-Tsy-119212	Tarsius syrichta	43.15	2.00e-71	263.00
IUUC-Tni-119915	Tetraodon nigroviridis	37.75	3.00e-84	305.00
IUUC-Tca-121765	Theobroma cacao	72.90	0.00e+00	1513.00
IUUC-Tre-121887	Trichoderma reesei	35.06	9.00e-61	228.00
IUUC-Tvi-122262	Trichoderma virens	35.06	4.00e-61	229.00
IUUC-Tae-123009	Triticum aestivum	60.11	0.00e+00	834.00
IUUC-Tur-126483	Triticum urartu	66.67	0.00e+00	1375.00
IUUC-Tme-127202	Tuber melanosporum	30.48	2.00e-49	190.00
IUUC-Tbe-127350	Tupaia belangeri	34.92	5.00e-51	195.00
IUUC-Ttr-129077	Tursiops truncatus	34.28	5.00e-74	271.00
IUUC-Uma-129465	Ustilago maydis	34.83	5.00e-70	258.00
IUUC-Vda-129844	Verticillium dahliae	33.00	3.00e-66	246.00
IUUC-Vvi-131397	Vitis vinifera	73.92	0.00e+00	1510.00
IUUC-Xtr-132057	Xenopus tropicalis	37.27	6.00e-86	311.00
IUUC-Xma-134139	Xiphophorus maculatus	39.36	3.00e-67	249.00
IUUC-Yli-134424	Yarrowia lipolytica	35.07	8.00e-65	241.00
IUUC-Zma-135839	Zea mays	69.48	0.00e+00	1342.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence