iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054132

UUCD1 version

UUC-LoA-01088

Ensembl Protein ID

ENSLAFP00000006189.3

UniProt Accession

G3SZU9; G3SZU9_LOXAF

Protein Name

Uncharacterized protein

Gene Name

USP40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000007360.3	ENSLAFT00000007361.3	ENSLAFP00000006189.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-78	264.9	42	482

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg....ellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           G++N+g tCY+NS+LQ+L+++pe+re+l++  +e+l   ++k++       +  +lq+lf++l+  +++a s+ +l+++++++++e  +
   Q: 42   GIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGSLEDKDKPDakvrIIPLQLQRLFAQLLLLDQEAASTADLTDSFGWTSNE--E 128
           9*****************************777777665543332234458899******************************98..* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           ++q+D+qE+ ++l+++le +l                            +++++li++l++g++ +qi+c++c+n+s+++e+fldl++ 
   Q: 129  MRQHDVQELNRILFSALEASL--------------------------VGTSGHDLIKRLYHGTIVNQIICQDCENISEKQEDFLDLTVT 191
           *********************..........................789*************************************** PP
   S: 176  vpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           v++ +      l+++L +++++ee ++++n y+c  c+++++a+k  kl+klP++L++ L Rf+f+  ++ r k +++++fpl+++l+p
   Q: 192  VKNVS-----GLEEALwNMYVEEEVFDCDNLYHCGACDRLVKAVKLAKLRKLPPFLTVSLLRFNFDFVKCERYKETSCYTFPLRINLKP 275
           *****.....9****************************************************************************** PP
   S: 264  fctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................................... 301
           fc+++e +++ + +Y+L++v++H+G++++GHY++y+k+                                                   
   Q: 276  FCEQSELDDS-EFIYDLFSVIIHKGGCHGGHYHVYIKDvdhlgnwrfhkeeskpdmnskdlpngeeiddplmilqailseeesnlipvd 363
           ****998875.****************************************************************************** PP
   S: 302  ...............................................................................ekgk....Wl 307
                                                                                          +       W+
   Q: 364  qlgqkllnkiglswnktyrrqygplrkflqlhsqvfllssdestvsllkncslqpksdfqrndqrvfktltsespglndS--TtcphWF 450
           *********************************************************99999999999999888887541..24578** PP
   S: 308  lfdDskVtevkeeevleetg..staYvlfYkr 337
            ++DskV+++ke++++++ +  ++aY+lfY++
   Q: 451  DINDSKVQPIKEKDIEQQFQgkESAYMLFYRK 482
           *****************9889*********98 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MFGDLFEEDS PSVSNNQYEK GKKLKTKALE PPAPREFTNL SGIRNQGGTC YLNSLLQTLH 60
FTPEFREALF SLGPEELGSL EDKDKPDAKV RIIPLQLQRL FAQLLLLDQE AASTADLTDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTGGGG ACCTATTTGA AGAGGATTCT CCCAGTGTGT CAAATAATCA GTATGAAAAA 60
GGGAAGAAGT TAAAGACTAA AGCTTTGGAG CCACCAGCCC CTAGAGAATT CACCAATTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

lav:100670072

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	81.28	0.00e+00	1895.00
IUUC-Apl-004105	Anas platyrhynchos	63.79	0.00e+00	1566.00
IUUC-Aca-004715	Anolis carolinensis	61.41	0.00e+00	1483.00
IUUC-Ame-011073	Astyanax mexicanus	46.94	0.00e+00	1032.00
IUUC-Bta-012487	Bos taurus	81.81	0.00e+00	1992.00
IUUC-Cja-018937	Callithrix jacchus	81.74	0.00e+00	2029.00
IUUC-Cfa-020645	Canis familiaris	78.56	0.00e+00	1253.00
IUUC-Cpo-022160	Cavia porcellus	77.71	0.00e+00	1916.00
IUUC-Csa-023078	Chlorocebus sabaeus	81.41	0.00e+00	2058.00
IUUC-Cho-025013	Choloepus hoffmanni	67.77	0.00e+00	842.00
IUUC-Csv-026193	Ciona savignyi	56.47	1.00e-58	219.00
IUUC-Dre-027416	Danio rerio	48.99	0.00e+00	1174.00
IUUC-Dno-029639	Dasypus novemcinctus	80.25	0.00e+00	1687.00
IUUC-Dor-030624	Dipodomys ordii	85.38	7.00e-146	511.00
IUUC-Ete-032626	Echinops telfairi	69.71	0.00e+00	843.00
IUUC-Eca-034208	Equus caballus	83.10	0.00e+00	2070.00
IUUC-Eeu-035340	Erinaceus europaeus	48.41	1.00e-97	351.00
IUUC-Fca-035886	Felis catus	73.36	0.00e+00	781.00
IUUC-Fal-036925	Ficedula albicollis	63.93	0.00e+00	1465.00
IUUC-Gmo-038597	Gadus morhua	45.10	0.00e+00	910.00
IUUC-Gga-041171	Gallus gallus	64.04	0.00e+00	1550.00
IUUC-Gac-041362	Gasterosteus aculeatus	45.69	0.00e+00	988.00
IUUC-Ggo-045069	Gorilla gorilla	79.95	0.00e+00	1837.00
IUUC-Hsa-046715	Homo sapiens	81.73	0.00e+00	2034.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	79.11	0.00e+00	1909.00
IUUC-Lch-050182	Latimeria chalumnae	53.01	0.00e+00	1179.00
IUUC-Loc-052705	Lepisosteus oculatus	54.70	0.00e+00	1300.00
IUUC-Mcc-055734	Macaca mulatta	82.05	0.00e+00	2063.00
IUUC-Meu-056135	Macropus eugenii	84.48	4.00e-112	399.00
IUUC-Mga-060092	Meleagris gallopavo	63.93	0.00e+00	1532.00
IUUC-Mmr-061546	Microcebus murinus	80.47	0.00e+00	1967.00
IUUC-Mdo-061935	Monodelphis domestica	62.89	0.00e+00	1552.00
IUUC-Mmu-063630	Mus musculus	77.61	0.00e+00	1950.00
IUUC-Mpu-066579	Mustela putorius furo	79.40	0.00e+00	1989.00
IUUC-Mlu-068034	Myotis lucifugus	82.05	0.00e+00	1982.00
IUUC-Nle-069082	Nomascus leucogenys	79.48	0.00e+00	1677.00
IUUC-Opr-070953	Ochotona princeps	69.11	0.00e+00	968.00
IUUC-Ont-072435	Oreochromis niloticus	46.59	0.00e+00	1094.00
IUUC-Oan-073339	Ornithorhynchus anatinus	66.77	0.00e+00	1593.00
IUUC-Ocu-073760	Oryctolagus cuniculus	79.22	0.00e+00	1959.00
IUUC-Ola-087015	Oryzias latipes	46.37	0.00e+00	946.00
IUUC-Oga-088960	Otolemur garnettii	82.05	0.00e+00	2043.00
IUUC-Oar-089853	Ovis aries	82.41	0.00e+00	2029.00
IUUC-Ptr-091093	Pan troglodytes	81.57	0.00e+00	2030.00
IUUC-Pan-091962	Papio anubis	80.86	0.00e+00	2036.00
IUUC-Psi-093691	Pelodiscus sinensis	66.61	0.00e+00	1644.00
IUUC-Pma-094428	Petromyzon marinus	65.47	3.00e-92	331.00
IUUC-Pfo-096983	Poecilia formosa	48.07	0.00e+00	1046.00
IUUC-Pab-097860	Pongo abelii	80.57	0.00e+00	1876.00
IUUC-Pca-100514	Procavia capensis	74.49	0.00e+00	723.00
IUUC-Pva-102771	Pteropus vampyrus	80.69	0.00e+00	1874.00
IUUC-Rno-105405	Rattus norvegicus	77.04	0.00e+00	1904.00
IUUC-Sha-107376	Sarcophilus harrisii	64.35	0.00e+00	1506.00
IUUC-Ssc-115819	Sus scrofa	76.80	0.00e+00	1367.00
IUUC-Tgu-117262	Taeniopygia guttata	62.65	0.00e+00	1527.00
IUUC-Tru-117601	Takifugu rubripes	46.44	0.00e+00	1088.00
IUUC-Tsy-118996	Tarsius syrichta	72.25	0.00e+00	1596.00
IUUC-Tni-120682	Tetraodon nigroviridis	42.52	0.00e+00	873.00
IUUC-Tbe-127616	Tupaia belangeri	61.85	0.00e+00	1213.00
IUUC-Ttr-129075	Tursiops truncatus	79.21	0.00e+00	1876.00
IUUC-Vpa-130108	Vicugna pacos	82.02	0.00e+00	1813.00
IUUC-Xtr-132623	Xenopus tropicalis	52.56	0.00e+00	1210.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence