iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022072

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02028921

Gene Name

KLHL21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000008435.3	ENSCPOT00000008512.2	ENSCPOP00000007586.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.20e-15	57.6	36	99
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	4.30e-08	32.4	135	163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    Dvilvvg.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           Dv+l+ + g+ f+ah +vLaa+S++F+a+f ++l+es+  ++v +++v p+ ++ ll+F+Ytg++ 
   Q: 36   DVTLEAAgGRDFPAH-AVLAAASPYFRAMFAGQLRESR-AERVRLHGVPPDMLQLLLDFSYTGRVA 99
           9*****99*******.79********************.************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkh 30
            Ncl++ +fA++++c  L++aa++fil+h
   Q: 135  ANCLDMQDFAEAFSCAGLASAAQRFILRH 163
           6***************************9 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MERPAPLAVL PFSDPAHALS LLRGLSQLRA ERKFLDVTLE AAGGRDFPAH AVLAAASPYF 60
RAMFAGQLRE SRAERVRLHG VPPDMLQLLL DFSYTGRVAV SGDNAEPLLR AADLLQFPAV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCGGC CGGCCCCCCT GGCGGTGCTG CCCTTCTCGG ACCCCGCGCA CGCCCTGAGC 60
CTGCTGCGCG GCCTGAGCCA GCTGCGCGCC GAGCGCAAGT TCCTGGACGT GACGCTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005827--C:polar microtubule
GO:0004842--F:ubiquitin-protein transferase activity
GO:0035853--P:chromosome passenger complex localization to spindle midzone
GO:0032465--P:regulation of cytokinesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001782	Ailuropoda melanoleuca	86.88	0.00e+00	911.00
IUUC-Apl-003189	Anas platyrhynchos	85.28	5.00e-141	493.00
IUUC-Ame-011774	Astyanax mexicanus	65.83	5.00e-135	473.00
IUUC-Bta-012367	Bos taurus	96.15	0.00e+00	1135.00
IUUC-Cja-019501	Callithrix jacchus	89.56	0.00e+00	1026.00
IUUC-Cfa-020550	Canis familiaris	95.98	0.00e+00	1132.00
IUUC-Csa-023364	Chlorocebus sabaeus	97.68	0.00e+00	1008.00
IUUC-Cin-025253	Ciona intestinalis	43.64	1.00e-144	506.00
IUUC-Csv-025871	Ciona savignyi	44.65	1.00e-150	526.00
IUUC-Dre-028694	Danio rerio	72.54	0.00e+00	852.00
IUUC-Dno-029082	Dasypus novemcinctus	93.57	0.00e+00	948.00
IUUC-Dor-030680	Dipodomys ordii	96.31	0.00e+00	1138.00
IUUC-Ete-032315	Echinops telfairi	94.47	0.00e+00	954.00
IUUC-Eca-033570	Equus caballus	93.47	0.00e+00	681.00
IUUC-Eeu-035067	Erinaceus europaeus	92.19	1.00e-141	496.00
IUUC-Fca-035663	Felis catus	88.51	8.00e-121	425.00
IUUC-Fal-037103	Ficedula albicollis	83.54	0.00e+00	886.00
IUUC-Gmo-039420	Gadus morhua	70.60	0.00e+00	830.00
IUUC-Gga-040161	Gallus gallus	83.04	0.00e+00	853.00
IUUC-Gac-041755	Gasterosteus aculeatus	72.28	0.00e+00	855.00
IUUC-Ggo-044899	Gorilla gorilla	97.25	0.00e+00	1120.00
IUUC-Hsa-045834	Homo sapiens	97.58	0.00e+00	1119.00
IUUC-Itr-048413	Ictidomys tridecemlineatus	96.65	0.00e+00	1139.00
IUUC-Lch-050338	Latimeria chalumnae	70.76	0.00e+00	867.00
IUUC-Loc-051780	Lepisosteus oculatus	74.61	0.00e+00	869.00
IUUC-Laf-053725	Loxodonta africana	94.50	0.00e+00	786.00
IUUC-Mcc-055032	Macaca mulatta	98.40	0.00e+00	971.00
IUUC-Meu-056661	Macropus eugenii	93.80	0.00e+00	762.00
IUUC-Mga-059821	Meleagris gallopavo	85.23	6.00e-125	439.00
IUUC-Mdo-062095	Monodelphis domestica	95.26	0.00e+00	956.00
IUUC-Mmu-063138	Mus musculus	95.64	0.00e+00	1130.00
IUUC-Mpu-066386	Mustela putorius furo	93.79	0.00e+00	627.00
IUUC-Mlu-067807	Myotis lucifugus	94.40	0.00e+00	695.00
IUUC-Nle-069181	Nomascus leucogenys	95.48	0.00e+00	1118.00
IUUC-Opr-070658	Ochotona princeps	95.98	0.00e+00	1161.00
IUUC-Ont-072209	Oreochromis niloticus	71.65	0.00e+00	843.00
IUUC-Oan-072861	Ornithorhynchus anatinus	90.95	2.00e-116	411.00
IUUC-Ocu-074631	Oryctolagus cuniculus	86.71	0.00e+00	988.00
IUUC-Ola-087553	Oryzias latipes	70.42	0.00e+00	831.00
IUUC-Oga-088782	Otolemur garnettii	96.31	0.00e+00	1136.00
IUUC-Oar-089634	Ovis aries	95.81	0.00e+00	1130.00
IUUC-Ptr-091259	Pan troglodytes	96.98	0.00e+00	833.00
IUUC-Pan-091734	Papio anubis	97.59	0.00e+00	1123.00
IUUC-Psi-092979	Pelodiscus sinensis	82.65	0.00e+00	912.00
IUUC-Pma-094459	Petromyzon marinus	53.99	3.00e-123	435.00
IUUC-Pfo-097446	Poecilia formosa	71.48	0.00e+00	843.00
IUUC-Pab-098765	Pongo abelii	96.31	0.00e+00	1134.00
IUUC-Pca-101018	Procavia capensis	99.42	3.00e-92	332.00
IUUC-Pva-102730	Pteropus vampyrus	92.13	0.00e+00	1077.00
IUUC-Rno-104972	Rattus norvegicus	95.14	0.00e+00	1127.00
IUUC-Ssc-115869	Sus scrofa	97.61	0.00e+00	969.00
IUUC-Tgu-116562	Taeniopygia guttata	83.39	0.00e+00	919.00
IUUC-Tru-118490	Takifugu rubripes	70.77	0.00e+00	835.00
IUUC-Tni-119898	Tetraodon nigroviridis	69.19	0.00e+00	804.00
IUUC-Ttr-128976	Tursiops truncatus	92.58	2.00e-142	499.00
IUUC-Xtr-132876	Xenopus tropicalis	74.74	0.00e+00	902.00
IUUC-Xma-133540	Xiphophorus maculatus	72.01	0.00e+00	847.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence