iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000196323.11	ENST00000445008.6	ENSP00000408079.1
ENSG00000196323.11	ENST00000525842.5	ENSP00000433457.1
ENSG00000196323.11	ENST00000357899.8	ENSP00000350574.4
ENSG00000196323.11	ENST00000530205.5	ENSP00000434177.1
ENSG00000196323.11	ENST00000529982.5	ENSP00000432558.1
ENSG00000196323.11	ENST00000527478.5	ENSP00000436187.1
ENSG00000196323.11	ENST00000528448.2	ENSP00000435413.2
ENSG00000196323.11	ENST00000615689.1	ENSP00000479214.1

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
UTRdb	AREsite	circBase	circRNADb
CircNet	miRTarBase	microRNA	TRANSFAC
RepTar	SomamiR	miRcode	RAID2
Protein-protein Interaction
HINT	InWeb_IM
Disease-associated Variation
GWASdb
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.70e-12	49.2	28	94

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +D+++ v+++ f+ahk+vLaa+S++F+  + ++ e+ + k+  +++ v  + f  ll++ Yt +l++n
   Q: 28   CDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDEN-KNVLDLHHVTVTGFIPLLEYAYTATLSIN 94
           8**********************************888.9************************9987 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

XTFTHSSSSH SQEMLGKLNM LRNDGHFCDI TIRVQDKIFR AHKVVLAACS DFFRTKLVGQ 60
AEDENKNVLD LHHVTVTGFI PLLEYAYTAT LSINTENIID VLAAASYMQM FSVASTCSEF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGCTCCCGG GCCCCCTCGC TCCTCCCCTC TGGCCCCTCC GAGCGCTGGG GGTGCTTCCC 60
TCCCCGCCTC CTCGCACTCC CACTCGCGGG CACGCCGGTG GCTGTGCCGC CATGCCCCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0046872--F:metal ion binding
GO:0003676--F:nucleic acid binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002216	Ailuropoda melanoleuca	95.41	0.00e+00	1070.00
IUUC-Apl-003224	Anas platyrhynchos	89.87	0.00e+00	1093.00
IUUC-Aca-005027	Anolis carolinensis	86.76	0.00e+00	1061.00
IUUC-Ame-011436	Astyanax mexicanus	63.06	3.00e-175	608.00
IUUC-Bta-012900	Bos taurus	93.95	0.00e+00	1134.00
IUUC-Cja-019130	Callithrix jacchus	91.44	0.00e+00	1004.00
IUUC-Cfa-020379	Canis familiaris	94.39	0.00e+00	801.00
IUUC-Cpo-022480	Cavia porcellus	93.23	0.00e+00	1031.00
IUUC-Csa-023868	Chlorocebus sabaeus	88.08	0.00e+00	952.00
IUUC-Cho-024974	Choloepus hoffmanni	93.23	0.00e+00	1031.00
IUUC-Dre-028392	Danio rerio	60.08	7.00e-142	497.00
IUUC-Dno-029879	Dasypus novemcinctus	93.95	0.00e+00	1140.00
IUUC-Dor-031018	Dipodomys ordii	96.09	4.00e-140	491.00
IUUC-Ete-033106	Echinops telfairi	79.93	0.00e+00	872.00
IUUC-Eca-034127	Equus caballus	93.95	0.00e+00	813.00
IUUC-Eeu-035198	Erinaceus europaeus	89.64	1.00e-118	420.00
IUUC-Fca-036351	Felis catus	93.72	0.00e+00	810.00
IUUC-Fal-036832	Ficedula albicollis	89.71	0.00e+00	1093.00
IUUC-Gmo-039704	Gadus morhua	69.69	0.00e+00	712.00
IUUC-Gga-040913	Gallus gallus	89.87	0.00e+00	1090.00
IUUC-Gac-042158	Gasterosteus aculeatus	71.43	0.00e+00	748.00
IUUC-Ggo-044822	Gorilla gorilla	96.43	0.00e+00	1070.00
IUUC-Itr-048969	Ictidomys tridecemlineatus	93.72	0.00e+00	813.00
IUUC-Lch-050169	Latimeria chalumnae	81.37	0.00e+00	967.00
IUUC-Loc-052495	Lepisosteus oculatus	77.78	0.00e+00	923.00
IUUC-Laf-054356	Loxodonta africana	92.84	0.00e+00	806.00
IUUC-Mcc-055510	Macaca mulatta	95.72	0.00e+00	1036.00
IUUC-Meu-056538	Macropus eugenii	89.00	0.00e+00	709.00
IUUC-Mga-059414	Meleagris gallopavo	90.11	0.00e+00	1014.00
IUUC-Mmr-061006	Microcebus murinus	95.34	0.00e+00	1053.00
IUUC-Mdo-062937	Monodelphis domestica	90.52	0.00e+00	1099.00
IUUC-Mmu-064085	Mus musculus	92.81	0.00e+00	1119.00
IUUC-Mac-065031	Musa acuminata	23.58	8.00e-08	52.40
IUUC-Mpu-066405	Mustela putorius furo	94.39	0.00e+00	816.00
IUUC-Mlu-067916	Myotis lucifugus	93.99	0.00e+00	1087.00
IUUC-Nle-069718	Nomascus leucogenys	95.52	0.00e+00	826.00
IUUC-Opr-070951	Ochotona princeps	92.82	0.00e+00	744.00
IUUC-Ont-071814	Oreochromis niloticus	71.18	1.00e-168	585.00
IUUC-Oan-073210	Ornithorhynchus anatinus	88.79	0.00e+00	772.00
IUUC-Ocu-074864	Oryctolagus cuniculus	93.72	0.00e+00	811.00
IUUC-Ola-087276	Oryzias latipes	73.43	0.00e+00	766.00
IUUC-Oga-087985	Otolemur garnettii	97.98	0.00e+00	1164.00
IUUC-Oar-089402	Ovis aries	94.28	0.00e+00	1139.00
IUUC-Ptr-091504	Pan troglodytes	95.96	0.00e+00	831.00
IUUC-Pan-091711	Papio anubis	96.41	0.00e+00	1142.00
IUUC-Psi-092945	Pelodiscus sinensis	91.60	0.00e+00	1094.00
IUUC-Pfo-096804	Poecilia formosa	73.21	0.00e+00	754.00
IUUC-Pab-098321	Pongo abelii	95.90	0.00e+00	1063.00
IUUC-Pva-102537	Pteropus vampyrus	95.01	0.00e+00	1055.00
IUUC-Rno-105465	Rattus norvegicus	92.60	0.00e+00	800.00
IUUC-Sha-107347	Sarcophilus harrisii	89.38	0.00e+00	1055.00
IUUC-Sar-113390	Sorex araneus	92.69	0.00e+00	1027.00
IUUC-Ssc-115763	Sus scrofa	97.31	0.00e+00	1147.00
IUUC-Tgu-116698	Taeniopygia guttata	90.03	0.00e+00	1097.00
IUUC-Tru-118775	Takifugu rubripes	72.99	0.00e+00	787.00
IUUC-Tni-119981	Tetraodon nigroviridis	65.86	1.00e-153	536.00
IUUC-Tbe-127540	Tupaia belangeri	80.69	1.00e-156	546.00
IUUC-Ttr-128322	Tursiops truncatus	94.83	0.00e+00	1028.00
IUUC-Vpa-130316	Vicugna pacos	96.69	2.00e-133	469.00
IUUC-Xtr-132732	Xenopus tropicalis	82.82	0.00e+00	985.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence