iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089936

Ensembl Protein ID

ENSOARP00000010463.1

UniProt Accession

W5PJ43; W5PJ43_SHEEP

Genbank Protein ID

ENSOARP00000010463

Protein Name

Non-specific serine/threonine protein kinase

Genbank Nucleotide ID

AMGL01029136

Gene Name

MARK4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000009757.1	ENSOART00000010618.1	ENSOARP00000010463.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	87.10	0.00e+00	1129.00	IUUC-Hsa-045897

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

LAGRTGAARH SRSVSPPQHG TLGSGRSSDK GPSWSSRSLG ARCRNSIASC PEEQPHVGNY 60
RLLRTIGKGN FAKVKLARHI LTGREVAIKI IDKTQLNPSS LQKLFREVRI MKGLNHPNIV 120

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Nucleotide Sequence
(Fasta)

CTGGCGGGTC GGACGGGCGC TGCCCGCCAC TCACGCTCCG TCTCCCCCCC TCAGCATGGC 60
ACCCTGGGCA GTGGCCGCTC CTCAGACAAG GGCCCATCCT GGTCCAGCCG CTCCCTGGGC 120

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Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR028375--KA1/Ssp2_C
IPR001772--KA1_dom
IPR011009--Kinase-like_dom
IPR033624--MARK/par1
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA

PROSITE

PS50032--KA1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF02149--KA1
PF00069--Pkinase
PF00627--UBA

SMART

SM00220--S_TKc
SM00165--UBA

Gene Ontology

GO:0005813--C:centrosome
GO:0036064--C:ciliary basal body
GO:0043005--C:neuron projection
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0050321--F:tau-protein kinase activity
GO:0030010--P:establishment of cell polarity
GO:0001578--P:microtubule bundle formation
GO:0007399--P:nervous system development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013546	Bos taurus	94.21	0.00e+00	928.00
IUUC-Cja-019522	Callithrix jacchus	87.11	0.00e+00	1106.00
IUUC-Cfa-020231	Canis familiaris	86.16	0.00e+00	1118.00
IUUC-Cpo-022532	Cavia porcellus	93.42	0.00e+00	861.00
IUUC-Csa-023700	Chlorocebus sabaeus	90.75	0.00e+00	859.00
IUUC-Dor-030478	Dipodomys ordii	89.75	0.00e+00	839.00
IUUC-Eca-033684	Equus caballus	91.49	0.00e+00	866.00
IUUC-Fca-035898	Felis catus	93.05	0.00e+00	928.00
IUUC-Ggo-044770	Gorilla gorilla	93.50	0.00e+00	902.00
IUUC-Hsa-045897	Homo sapiens	93.81	0.00e+00	914.00
IUUC-Itr-049080	Ictidomys tridecemlineatus	86.96	0.00e+00	1145.00
IUUC-Laf-053534	Loxodonta africana	88.39	0.00e+00	867.00
IUUC-Mcc-054804	Macaca mulatta	94.20	0.00e+00	896.00
IUUC-Meu-056140	Macropus eugenii	83.42	0.00e+00	1115.00
IUUC-Mmr-060587	Microcebus murinus	93.04	0.00e+00	926.00
IUUC-Mlu-067933	Myotis lucifugus	91.42	0.00e+00	805.00
IUUC-Nle-069719	Nomascus leucogenys	84.77	0.00e+00	660.00
IUUC-Opr-070607	Ochotona princeps	82.75	0.00e+00	793.00
IUUC-Ola-086790	Oryzias latipes	74.53	0.00e+00	766.00
IUUC-Oga-088194	Otolemur garnettii	93.62	0.00e+00	892.00
IUUC-Ptr-091413	Pan troglodytes	94.00	0.00e+00	895.00
IUUC-Pab-098074	Pongo abelii	93.62	0.00e+00	889.00
IUUC-Pva-103242	Pteropus vampyrus	94.00	0.00e+00	870.00
IUUC-Ttr-129093	Tursiops truncatus	90.14	0.00e+00	846.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence