iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045323

UUCD1 version

UUC-GoG-01115

Ensembl Protein ID

ENSGGOP00000009835.2

UniProt Accession

G3R3K5; G3R3K5_GORGO

Protein Name

Uncharacterized protein

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000010079.2	ENSGGOT00000010118.2	ENSGGOP00000009835.2
ENSGGOG00000010079.2	ENSGGOT00000022641.1	ENSGGOP00000022949.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.70e-82	277.7	346	830

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCY+NS+LQ+L++ +++r+++l+     l e+    ++++l+++lq lf  l +s++ a+sp+++l+a +   + fs   qq
   Q: 346  GLINLGNTCYVNSILQALFMASDFRHCVLR-----LTEN----NSQPLMTKLQWLFGFLEHSQRPAISPENFLSASW--TPWFSPGTQQ 423
           9*****************************.....4433....3579***************************998..677******* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           D++E+l++lld+l+ee      k+ ++ +++ k+++s + +e+++  +++ ++++F+g++ ++i cl c nvssree f+dlsl++p  
   Q: 424  DCSEYLKYLLDRLHEEE-----KTGTRICQKLKQSSSPSPPEEPPAPSSTSVEKMFGGTIVTRICCLCCLNVSSREEAFTDLSLAFPPP 507
           *****************.....67888888888999999999*********************************************99 PP
   S: 180  eetkke................................................................................... 185
           e +  +                                                                                   
   Q: 508  ERCRRRrlgsvmrptediparelppptsaqgpgrvgprrqrkhcitedtpptslyiegldskeaggqssqeervereeegkeertekee 596
           98877799********************************************************************************* PP
   S: 186  ...................................................................slqdcLesftkeeelegenkyy 207
                                                                              s+ d+ + f ++e+l+ en+yy
   Q: 597  vgeeeestrgeeerekeeeveeeeekveketekeaeqekeedslgagthpdaaipsgeqtcgsegsrSVLDLVNYFLSPEKLTAENRYY 685
           ***************************************************************************************** PP
   S: 208  cekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHY 295
           ce+c ++q+aek ++l++ P++Lil L Rfsf+ ++++r+ki + v++pl L l     +        + Y+L++vvvHsG s++sGHY
   Q: 686  CESCASLQDAEKVVELSQGPRYLILTLLRFSFDLRTMRRRKILDDVSIPLLLRLPLAGGR-------GQAYDLCSVVVHSGvSSESGHY 767
           *************************************************99999855555.......89******************** PP
   S: 296  vayvkn................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
           ++y+++                 +++W+lf+D++V+ ++ e+v + t+    +taYvlfY++r
   Q: 768  YCYAREgaarpapslgtadrpePENQWYLFNDTRVSFSSFESVSNVTSffpkDTAYVLFYRQR 830
           ******99999999999999888999*******************999************985 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MDKILEAVVT SSYPVSVKQG LVRRVLEAAR QPLEREQCLA LLALGARLYV LLARHPRCVP 60
DGPHRLLFCQ QLVRCLGRFR CPAEGEEGAV EFLEQAQQVS GLLAQLWRAQ PAGILPCLKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TCTTGGAGGC GGTGGTGACG TCGTCATACC CGGTCAGCGT GAAGCAGGGG 60
CTGGTTCGGC GCGTGCTGGA GGCGGCGCGG CAGCCGCTGG AGCGTGAGCA GTGCCTGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001744	Ailuropoda melanoleuca	89.82	0.00e+00	984.00
IUUC-Aca-005070	Anolis carolinensis	65.34	2.00e-163	569.00
IUUC-Bta-012545	Bos taurus	91.40	0.00e+00	923.00
IUUC-Cja-019731	Callithrix jacchus	96.20	0.00e+00	974.00
IUUC-Cfa-020095	Canis familiaris	93.16	0.00e+00	945.00
IUUC-Cpo-021961	Cavia porcellus	91.89	0.00e+00	895.00
IUUC-Csa-023167	Chlorocebus sabaeus	97.34	0.00e+00	956.00
IUUC-Csv-026333	Ciona savignyi	40.48	4.00e-25	107.00
IUUC-Dno-029186	Dasypus novemcinctus	83.24	0.00e+00	770.00
IUUC-Dor-030538	Dipodomys ordii	98.44	0.00e+00	786.00
IUUC-Dme-031871	Drosophila melanogaster	31.68	2.00e-46	180.00
IUUC-Ete-032512	Echinops telfairi	89.33	2.00e-105	376.00
IUUC-Eca-033279	Equus caballus	96.92	0.00e+00	860.00
IUUC-Eeu-035120	Erinaceus europaeus	67.88	0.00e+00	652.00
IUUC-Fca-035969	Felis catus	92.45	0.00e+00	888.00
IUUC-Hsa-046124	Homo sapiens	99.04	0.00e+00	973.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	92.94	0.00e+00	921.00
IUUC-Laf-053999	Loxodonta africana	88.64	0.00e+00	902.00
IUUC-Mcc-055266	Macaca mulatta	96.21	0.00e+00	937.00
IUUC-Meu-056906	Macropus eugenii	79.32	0.00e+00	820.00
IUUC-Mmr-061720	Microcebus murinus	93.09	0.00e+00	713.00
IUUC-Mdo-062167	Monodelphis domestica	79.16	0.00e+00	816.00
IUUC-Mmu-063298	Mus musculus	90.32	0.00e+00	924.00
IUUC-Mpu-066195	Mustela putorius furo	92.76	0.00e+00	931.00
IUUC-Mlu-067583	Myotis lucifugus	88.25	0.00e+00	778.00
IUUC-Opr-070454	Ochotona princeps	80.09	2.00e-91	330.00
IUUC-Ocu-074121	Oryctolagus cuniculus	85.75	0.00e+00	761.00
IUUC-Oga-088593	Otolemur garnettii	93.35	0.00e+00	917.00
IUUC-Oar-090140	Ovis aries	90.63	0.00e+00	905.00
IUUC-Pan-092168	Papio anubis	97.72	0.00e+00	958.00
IUUC-Pab-097614	Pongo abelii	98.17	0.00e+00	1386.00
IUUC-Pca-100683	Procavia capensis	86.29	0.00e+00	860.00
IUUC-Pva-103146	Pteropus vampyrus	83.46	0.00e+00	848.00
IUUC-Rno-105061	Rattus norvegicus	90.70	0.00e+00	929.00
IUUC-Sha-106686	Sarcophilus harrisii	76.84	0.00e+00	801.00
IUUC-Tsy-119505	Tarsius syrichta	80.65	3.00e-166	578.00
IUUC-Tbe-127723	Tupaia belangeri	88.70	5.00e-97	348.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence