iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118623

UUCD1 version

UUC-TaR-01151

Ensembl Protein ID

ENSTRUP00000035924.1

UniProt Accession

H2UG54; H2UG54_TAKRU

Protein Name

Uncharacterized protein

Gene Name

usp38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000014044.1	ENSTRUT00000036054.1	ENSTRUP00000035924.1
ENSTRUG00000014044.1	ENSTRUT00000036055.1	ENSTRUP00000035925.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.10e-79	267.2	449	922

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtC+mNS++Q+L++ +++r+ +l+    +ln +      ++l+k+lq lf+ l ++++ a++pr++l+a +   + f+  +q
   Q: 449  TGLINLGNTCFMNSIIQTLFMATDFRHHVLS---LHLNGS------NSLMKKLQLLFAFLAHTQRAAYAPRNFLEASR--PPWFNAGSQ 526
           7******************************...666665......48***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk.............eknkpkeeeeeedkselsde................aeekkkkknkslisdlFqgq 149
           qD++E+l+flld+l+ee k              +                ++                  e  ++++ k+li+++F+g+
   Q: 527  QDCSEYLRFLLDRLHEEEKTihvlesvkpklasH---------------VDSTrtdpagqtppemghesPETGPQEERKTLIETMFGGT 600
           ******************6666554333322221...............111133344566777777666667788888********** PP
   S: 150  lksqikclecdnvssreepfldlslpvpgkeetkke................................................slqdc 190
           l ++i+cl+c+ +s++eepf+dlsl++  + ++  +                                                ++ d+
   Q: 601  LLTRIRCLQCHCISEKEEPFTDLSLAFCPSATSRYSsqperpseepkglyqgsvnggseildpgssasqvssvhsvtvtnepslTVPDM 689
           ***************************9988777778999************************************************* PP
   S: 191  LesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts............ 267
            + f ++e l+++n+y+cekc ++q+aek++++ + Pe+Lil L Rfs++ + ++r+ki ++v++p  + l  +  s            
   Q: 690  VNYFLAPEILDEDNAYFCEKCSSLQRAEKTMQVVSAPEYLILTLLRFSYDAKFHVRRKILENVTIPPLMRLPVYSRSkpsesfcpasss 778
           ******************************************************************98999877777777777777777 PP
   S: 268  .....................peekqke.....kkkYeLiavvvHsG.slssGHYvayvkn............................ 301
                                +     e     +  Y L++vvvHsG s++sGHY++y +n                            
   Q: 779  qhldcpessenlakklkpsqqD-----EkdeiqPALYVLSSVVVHSGvSSESGHYYSYGRNidgadgsqhparhsplnealqngqaecn 862
           7777777777777666655543.....044555******************************************************** PP
   S: 302  ...................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                              e ++Wllf+Ds+Vt ++ + v++ t+    +taYvl+Y+++
   Q: 863  psncsalsippqqagssgqEAKDWLLFNDSRVTFSSFQLVQNITNrfpkDTAYVLMYRKQ 922
           ****9999999999987755666*******************999************986 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

QAAIMDKILE GLVCSDHSVT VKRAIVKRVV EAAEDDATEE QCLSMFTLTT RLFLLGEDAF 60
QKQTGVQVLD AYARCHRTEF EHFFSKDFVL ILLQQGFGHL DRKDPAIIDY IHCCLRLLIS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGCCGCCA TCATGGACAA AATTTTGGAA GGCCTGGTAT GCTCCGACCA CTCTGTTACA 60
GTGAAACGAG CCATAGTGAA GCGGGTAGTG GAAGCGGCAG AGGATGACGC GACTGAGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	63.16	0.00e+00	1144.00
IUUC-Apl-003435	Anas platyrhynchos	60.70	0.00e+00	960.00
IUUC-Aca-004556	Anolis carolinensis	58.33	0.00e+00	977.00
IUUC-Ame-010616	Astyanax mexicanus	66.51	0.00e+00	1266.00
IUUC-Bta-013544	Bos taurus	62.37	0.00e+00	1134.00
IUUC-Cja-018745	Callithrix jacchus	62.16	0.00e+00	1152.00
IUUC-Cfa-020434	Canis familiaris	61.81	0.00e+00	1105.00
IUUC-Cpo-021666	Cavia porcellus	63.02	0.00e+00	1129.00
IUUC-Csa-023965	Chlorocebus sabaeus	62.97	0.00e+00	1179.00
IUUC-Cho-024809	Choloepus hoffmanni	54.59	0.00e+00	700.00
IUUC-Cin-025604	Ciona intestinalis	29.86	2.00e-40	159.00
IUUC-Csv-026333	Ciona savignyi	42.78	1.00e-31	129.00
IUUC-Dre-028338	Danio rerio	66.76	0.00e+00	1290.00
IUUC-Dno-029372	Dasypus novemcinctus	62.45	0.00e+00	1156.00
IUUC-Dor-030752	Dipodomys ordii	59.72	0.00e+00	732.00
IUUC-Dme-031871	Drosophila melanogaster	28.18	1.00e-54	208.00
IUUC-Ete-032588	Echinops telfairi	54.55	0.00e+00	684.00
IUUC-Eca-034416	Equus caballus	63.14	0.00e+00	1165.00
IUUC-Eeu-035132	Erinaceus europaeus	49.62	0.00e+00	808.00
IUUC-Fca-036137	Felis catus	63.53	0.00e+00	1162.00
IUUC-Fal-037297	Ficedula albicollis	60.15	0.00e+00	1087.00
IUUC-Gmo-038727	Gadus morhua	77.36	0.00e+00	1161.00
IUUC-Gga-041091	Gallus gallus	60.04	0.00e+00	1068.00
IUUC-Gac-042082	Gasterosteus aculeatus	81.08	0.00e+00	1476.00
IUUC-Ggo-045376	Gorilla gorilla	59.57	0.00e+00	1063.00
IUUC-Hsa-046444	Homo sapiens	63.38	0.00e+00	1179.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	63.20	0.00e+00	1159.00
IUUC-Lch-050500	Latimeria chalumnae	62.90	0.00e+00	1170.00
IUUC-Loc-052625	Lepisosteus oculatus	68.83	0.00e+00	1312.00
IUUC-Laf-053689	Loxodonta africana	62.88	0.00e+00	1156.00
IUUC-Mcc-055286	Macaca mulatta	63.15	0.00e+00	1170.00
IUUC-Meu-056906	Macropus eugenii	48.73	4.00e-175	608.00
IUUC-Mga-059905	Meleagris gallopavo	59.63	0.00e+00	904.00
IUUC-Mmr-061397	Microcebus murinus	63.12	0.00e+00	1143.00
IUUC-Mdo-062833	Monodelphis domestica	63.36	0.00e+00	1204.00
IUUC-Mmu-063157	Mus musculus	62.18	0.00e+00	1139.00
IUUC-Mpu-066434	Mustela putorius furo	63.31	0.00e+00	1169.00
IUUC-Mlu-068178	Myotis lucifugus	63.05	0.00e+00	1127.00
IUUC-Nle-070153	Nomascus leucogenys	62.71	0.00e+00	1134.00
IUUC-Opr-070454	Ochotona princeps	42.82	2.00e-64	241.00
IUUC-Ont-072330	Oreochromis niloticus	78.05	0.00e+00	1506.00
IUUC-Oan-072709	Ornithorhynchus anatinus	62.07	0.00e+00	877.00
IUUC-Ocu-074832	Oryctolagus cuniculus	63.35	0.00e+00	1147.00
IUUC-Ola-087003	Oryzias latipes	71.35	2.00e-62	231.00
IUUC-Oga-088517	Otolemur garnettii	63.29	0.00e+00	1002.00
IUUC-Oar-089472	Ovis aries	59.30	0.00e+00	1054.00
IUUC-Ptr-090996	Pan troglodytes	63.28	0.00e+00	1177.00
IUUC-Pan-091837	Papio anubis	61.57	0.00e+00	1130.00
IUUC-Psi-093236	Pelodiscus sinensis	60.62	0.00e+00	857.00
IUUC-Pma-094349	Petromyzon marinus	51.56	0.00e+00	885.00
IUUC-Pfo-097193	Poecilia formosa	74.54	0.00e+00	1397.00
IUUC-Pab-098710	Pongo abelii	63.53	0.00e+00	1195.00
IUUC-Pca-100794	Procavia capensis	54.92	0.00e+00	970.00
IUUC-Pva-102722	Pteropus vampyrus	63.19	0.00e+00	1162.00
IUUC-Rno-105743	Rattus norvegicus	62.18	0.00e+00	1133.00
IUUC-Sha-106563	Sarcophilus harrisii	62.36	0.00e+00	944.00
IUUC-Sar-113533	Sorex araneus	55.79	0.00e+00	987.00
IUUC-Ssc-116259	Sus scrofa	57.98	0.00e+00	989.00
IUUC-Tgu-117475	Taeniopygia guttata	59.94	0.00e+00	984.00
IUUC-Tsy-119250	Tarsius syrichta	60.36	0.00e+00	848.00
IUUC-Tni-120441	Tetraodon nigroviridis	85.70	0.00e+00	1630.00
IUUC-Tbe-127936	Tupaia belangeri	52.66	0.00e+00	867.00
IUUC-Ttr-128483	Tursiops truncatus	53.19	0.00e+00	821.00
IUUC-Vpa-130303	Vicugna pacos	77.34	0.00e+00	818.00
IUUC-Xtr-132773	Xenopus tropicalis	60.14	0.00e+00	1096.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence