iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012323

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02028332

Gene Name

TEP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000001179.5	ENSBTAT00000001564.4	ENSBTAP00000001564.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.60e-48	160.0	2068	2103
UBD/Beta-Prp	1.80e-74	250.7	1935	2191

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gH+++v+c++f +d ++l++G++D ++ +WD+rt +
   Q: 2068 GHEGPVSCCSFsTDgCRLATGGRDRSLLCWDVRTPK 2103
           8***********889*****************9976 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls..tgkcvhtlkgh 93
           h s+  +v+ spd++++a+g+r + i++ ++++ +  ++ +  + +v+a+++ + + +lv+g+eD++++ w l+  t + +  l++h
   Q: 1935 HLSPALSVALSPDGDQVAVGYRADGIRICRISSASQGAQGQALDVAVSALTWLSPK-VLVSGAEDGALQGWLLQggTLQSLWLLSRH 2020
           6677788999***********************9998888888899*****99996.**************99955667777888** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqclee........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktg 169
            + vl l+ s+  + l+++s+d t+r+w  +     ++         l+gh+g v+c +++ dg+ l++G+ Dr +  Wd+   k  
   Q: 2021 RKPVLGLATSQ--ELLAIASEDFTVRLWPRQLLMLPQKtedfprstELRGHEGPVSCCSFSTDGCRLATGGRDRSLLCWDVrtpKAP 2105
           ***********..***************665555444488899**9***********************************776677 PP
   S: 170  kllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdl 256
            l+  ++  h d v+  ++++++  lvs+s dg+v lwd ++ + +  + gh+  v+ v +   +e++vs++ Dg++++Wd +  ++
   Q: 2106 VLICSFSACHRDWVTGCAWTKDS-LLVSCSSDGSVALWDPESRQQLGHFLGHQHAVSAVVAV--EEHVVSVGRDGTLKVWDHQGVEM 2189
           79*******************96.************************************99..****************9665444 PP
   S: 257  lk 258
           ++
   Q: 2190 TS 2191
           44 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MLEKPPGHVS THSDILSLEN RCLATLPDLK TLEKPPGHMS AHSDILSSEN RCLATLPDLK 60
TLEKPPGHVS AHSDILSLEN RCLATLPDLK TLEKPPGHVS AHSDILSLEN RCLATLTILK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGGAGA AACCACCTGG GCATGTGTCT ACTCACTCAG ACATCCTCTC CTTGGAGAAC 60
CGGTGCCTGG CCACCCTTCC TGACCTGAAG ACCTTGGAGA AACCACCTGG GCATATGTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR025139--DUF4062
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase
IPR008850--TEP1_N
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50837--NACHT
PS51226--TEP1_N
PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05386--TEP1_N
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0071011--C:precatalytic spliceosome
GO:0005697--C:telomerase holoenzyme complex
GO:0005682--C:U5 snRNP
GO:0003720--F:telomerase activity
GO:0070034--F:telomerase RNA binding
GO:0008380--P:RNA splicing
GO:0000722--P:telomere maintenance via recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001482	Ailuropoda melanoleuca	79.42	0.00e+00	3825.00
IUUC-Aca-005102	Anolis carolinensis	42.92	0.00e+00	1642.00
IUUC-Ame-011822	Astyanax mexicanus	34.81	0.00e+00	630.00
IUUC-Cja-019005	Callithrix jacchus	79.38	0.00e+00	3997.00
IUUC-Cfa-020803	Canis familiaris	72.56	0.00e+00	3404.00
IUUC-Cpo-022312	Cavia porcellus	73.08	0.00e+00	3381.00
IUUC-Csa-023287	Chlorocebus sabaeus	79.72	0.00e+00	3969.00
IUUC-Dre-028825	Danio rerio	35.11	0.00e+00	1149.00
IUUC-Dno-029455	Dasypus novemcinctus	77.75	0.00e+00	3727.00
IUUC-Dor-030328	Dipodomys ordii	71.71	0.00e+00	2456.00
IUUC-Ete-032385	Echinops telfairi	73.50	0.00e+00	1892.00
IUUC-Eca-033726	Equus caballus	82.73	0.00e+00	4126.00
IUUC-Eeu-034665	Erinaceus europaeus	63.56	0.00e+00	946.00
IUUC-Fca-035365	Felis catus	80.80	0.00e+00	3942.00
IUUC-Gmo-039584	Gadus morhua	31.71	1.00e-117	418.00
IUUC-Gac-042307	Gasterosteus aculeatus	35.73	0.00e+00	999.00
IUUC-Ggo-045432	Gorilla gorilla	77.64	0.00e+00	3732.00
IUUC-Hsa-046182	Homo sapiens	79.67	0.00e+00	3978.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	77.94	0.00e+00	3821.00
IUUC-Lch-050186	Latimeria chalumnae	39.67	6.00e-79	288.00
IUUC-Laf-054524	Loxodonta africana	77.92	0.00e+00	3899.00
IUUC-Mcc-055628	Macaca mulatta	80.27	0.00e+00	4004.00
IUUC-Meu-056338	Macropus eugenii	63.42	0.00e+00	1297.00
IUUC-Mmr-060854	Microcebus murinus	79.45	0.00e+00	3907.00
IUUC-Mdo-062247	Monodelphis domestica	61.20	0.00e+00	2734.00
IUUC-Mmu-064406	Mus musculus	71.78	0.00e+00	3494.00
IUUC-Mpu-065806	Mustela putorius furo	78.94	0.00e+00	3897.00
IUUC-Mlu-068116	Myotis lucifugus	81.14	0.00e+00	3899.00
IUUC-Nle-069628	Nomascus leucogenys	80.13	0.00e+00	3529.00
IUUC-Opr-070242	Ochotona princeps	77.88	0.00e+00	2768.00
IUUC-Oan-073598	Ornithorhynchus anatinus	52.08	0.00e+00	1880.00
IUUC-Ocu-073933	Oryctolagus cuniculus	77.89	0.00e+00	3792.00
IUUC-Ola-086886	Oryzias latipes	35.59	0.00e+00	1031.00
IUUC-Oga-088609	Otolemur garnettii	77.38	0.00e+00	3768.00
IUUC-Oar-089957	Ovis aries	94.48	0.00e+00	4653.00
IUUC-Ptr-090577	Pan troglodytes	78.38	0.00e+00	3914.00
IUUC-Pan-092397	Papio anubis	79.75	0.00e+00	3994.00
IUUC-Pma-094373	Petromyzon marinus	35.78	3.00e-73	269.00
IUUC-Pfo-096497	Poecilia formosa	36.41	0.00e+00	1075.00
IUUC-Pab-098028	Pongo abelii	79.59	0.00e+00	3934.00
IUUC-Pca-101002	Procavia capensis	83.15	0.00e+00	1884.00
IUUC-Pva-102144	Pteropus vampyrus	74.12	0.00e+00	1698.00
IUUC-Rno-105828	Rattus norvegicus	70.92	0.00e+00	3495.00
IUUC-Sha-106469	Sarcophilus harrisii	60.57	0.00e+00	2825.00
IUUC-Sar-113035	Sorex araneus	72.44	0.00e+00	2070.00
IUUC-Ssc-116122	Sus scrofa	86.70	0.00e+00	3166.00
IUUC-Tru-118412	Takifugu rubripes	33.15	0.00e+00	1137.00
IUUC-Tsy-119257	Tarsius syrichta	72.43	0.00e+00	1514.00
IUUC-Tni-120032	Tetraodon nigroviridis	33.00	4.00e-38	151.00
IUUC-Tbe-127312	Tupaia belangeri	62.72	0.00e+00	885.00
IUUC-Ttr-128335	Tursiops truncatus	85.13	0.00e+00	4282.00
IUUC-Xtr-132524	Xenopus tropicalis	38.83	0.00e+00	1347.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence