iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000010031.2	ENSSTOT00000010060.2	ENSSTOP00000009023.2
ENSSTOG00000010031.2	ENSSTOT00000027484.1	ENSSTOP00000020821.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-53	176.2	2085	2120
UBD/Beta-Prp	2.70e-78	263.2	1911	2155

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlrtgvll 36
           H d+vt++++  d+ll+s+s Dg++ +WD+++g +l
   Q: 2085 HRDWVTGCSWtKDNLLLSCSTDGSVGLWDPDSGQQL 2120
           9*********877*****************999876 PP

UBD/Beta-Prp

   S: 15   cvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls..tgkcvhtlkghedsvls 99
           +v+ spd++ +a+g+r + i+++++++g+  ++ +  + +v+a+ + +++ +lv+g+eD+ ++ w l+  + + +  l++ ++ vl 
   Q: 1911 SVALSPDGDRVAVGYRADGIRIYKISPGSQGAQCQVLDVAVSALAWLSSR-VLVSGAEDGSLQGWVLKehSLQSLWLLSRSQKPVLG 1996
           46677888888888888888888888888888888888888888888886.888888888888886663355566666778888888 PP
   S: 100  lsfspsgdklvsGshdrtirvwdletgqclee...........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkll 172
           l+ s+  + l+++s+d t+r+w   ++q l +            l gh+g vnc ++++dg  l++G+ Dr +  Wd+   +t  l+
   Q: 1997 LATSQ--ELLAAASEDFTVRLW---SRQLLMQplkaedflcdtELLGHQGPVNCCSFSSDGGRLATGGRDRNLLCWDVrmpQTPLLI 2078
           88888..888888888888888...66666666667888877777788888888888888888888888888888888666667788 PP
   S: 173  rtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlr 252
           r +   h d v+  s++++ + l+s+s+dg+v lwd  +g+ + +++gh++ v+ v +   +e++vs++ Dg +++Wd +
   Q: 2079 RSFPACHRDWVTGCSWTKD-NLLLSCSTDGSVGLWDPDSGQQLGQFRGHQSAVSAVVAV--EEHVVSVGRDGALKVWDHQ 2155
           8887778888888888886.588888888888888888888888888888888888777..7888888888888888754 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MEKLRGHVSA HPDVLSLENR CLAMLPVLQP LEKTHESMSA HSDILSLKSQ CLVRILDLKT 60
MEKPHRHVSA HPDILSLENR CLATLPSVKS TVSASPLFQC LQIPHMMQTD LCSLNTSNRL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGAAAC TCCGTGGGCA TGTTTCTGCC CACCCAGACG TCCTCTCATT GGAGAATCGG 60
TGCCTGGCCA TGCTCCCCGT CTTGCAGCCC TTGGAGAAAA CACATGAAAG TATGTCTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR025139--DUF4062
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase
IPR002469--Peptidase_S9B_N
IPR011047--Quinoprotein_ADH-like_supfam
IPR008850--TEP1_N
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50837--NACHT
PS51226--TEP1_N
PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05386--TEP1_N
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005697--C:telomerase holoenzyme complex
GO:0003720--F:telomerase activity
GO:0070034--F:telomerase RNA binding
GO:0000722--P:telomere maintenance via recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001482	Ailuropoda melanoleuca	76.49	0.00e+00	3690.00
IUUC-Aca-005102	Anolis carolinensis	42.18	0.00e+00	1611.00
IUUC-Ame-011822	Astyanax mexicanus	34.20	4.00e-174	606.00
IUUC-Bta-012323	Bos taurus	77.55	0.00e+00	3763.00
IUUC-Cja-019005	Callithrix jacchus	80.42	0.00e+00	4040.00
IUUC-Cfa-020803	Canis familiaris	69.91	0.00e+00	3276.00
IUUC-Cpo-022312	Cavia porcellus	74.86	0.00e+00	3533.00
IUUC-Csa-023287	Chlorocebus sabaeus	81.01	0.00e+00	4001.00
IUUC-Dre-028825	Danio rerio	34.91	0.00e+00	1136.00
IUUC-Dno-029455	Dasypus novemcinctus	77.41	0.00e+00	3720.00
IUUC-Dor-030328	Dipodomys ordii	75.56	0.00e+00	2645.00
IUUC-Ete-032385	Echinops telfairi	71.65	0.00e+00	1884.00
IUUC-Eca-033726	Equus caballus	80.94	0.00e+00	4013.00
IUUC-Eeu-034665	Erinaceus europaeus	64.94	0.00e+00	932.00
IUUC-Fca-035365	Felis catus	78.26	0.00e+00	3810.00
IUUC-Gmo-039584	Gadus morhua	30.76	1.00e-113	404.00
IUUC-Gac-042307	Gasterosteus aculeatus	35.99	0.00e+00	1003.00
IUUC-Ggo-045432	Gorilla gorilla	78.76	0.00e+00	3809.00
IUUC-Hsa-046182	Homo sapiens	80.61	0.00e+00	4004.00
IUUC-Lch-050186	Latimeria chalumnae	37.94	1.00e-73	270.00
IUUC-Laf-054524	Loxodonta africana	76.47	0.00e+00	3860.00
IUUC-Mcc-055628	Macaca mulatta	81.12	0.00e+00	4009.00
IUUC-Meu-056338	Macropus eugenii	61.88	0.00e+00	1271.00
IUUC-Mmr-060854	Microcebus murinus	80.07	0.00e+00	3953.00
IUUC-Mdo-062247	Monodelphis domestica	60.33	0.00e+00	2722.00
IUUC-Mmu-064406	Mus musculus	75.48	0.00e+00	3686.00
IUUC-Mpu-065806	Mustela putorius furo	76.38	0.00e+00	3747.00
IUUC-Mlu-068116	Myotis lucifugus	79.27	0.00e+00	3804.00
IUUC-Nle-069628	Nomascus leucogenys	81.36	0.00e+00	3595.00
IUUC-Opr-070242	Ochotona princeps	76.96	0.00e+00	2739.00
IUUC-Oan-073598	Ornithorhynchus anatinus	51.80	0.00e+00	1898.00
IUUC-Ocu-073933	Oryctolagus cuniculus	78.05	0.00e+00	3812.00
IUUC-Ola-086886	Oryzias latipes	35.12	0.00e+00	1069.00
IUUC-Oga-088609	Otolemur garnettii	78.82	0.00e+00	3837.00
IUUC-Oar-089957	Ovis aries	77.43	0.00e+00	3682.00
IUUC-Ptr-090577	Pan troglodytes	79.27	0.00e+00	3921.00
IUUC-Pan-092397	Papio anubis	80.83	0.00e+00	4001.00
IUUC-Pma-094373	Petromyzon marinus	33.28	9.00e-67	248.00
IUUC-Pfo-096497	Poecilia formosa	35.80	0.00e+00	1061.00
IUUC-Pab-098028	Pongo abelii	80.38	0.00e+00	3952.00
IUUC-Pca-101002	Procavia capensis	81.08	0.00e+00	1848.00
IUUC-Pva-102144	Pteropus vampyrus	73.66	0.00e+00	1678.00
IUUC-Rno-105828	Rattus norvegicus	74.38	0.00e+00	3708.00
IUUC-Sha-106469	Sarcophilus harrisii	60.22	0.00e+00	2777.00
IUUC-Sar-113035	Sorex araneus	76.13	0.00e+00	1431.00
IUUC-Ssc-116122	Sus scrofa	80.59	0.00e+00	2908.00
IUUC-Tru-118412	Takifugu rubripes	32.58	0.00e+00	1149.00
IUUC-Tsy-119257	Tarsius syrichta	74.11	0.00e+00	1531.00
IUUC-Tni-120032	Tetraodon nigroviridis	32.04	2.00e-35	142.00
IUUC-Tbe-127312	Tupaia belangeri	64.60	0.00e+00	972.00
IUUC-Ttr-128335	Tursiops truncatus	75.68	0.00e+00	3703.00
IUUC-Xtr-132524	Xenopus tropicalis	39.25	0.00e+00	1375.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence