iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-044457

Ensembl Protein ID

ENSGGOP00000019352.1

UniProt Accession

G3RU75; G3RU75_GORGO

Protein Name

Uncharacterized protein

Gene Name

KIF21A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000001632.2	ENSGGOT00000030296.1	ENSGGOP00000019352.1
ENSGGOG00000001632.2	ENSGGOT00000001646.2	ENSGGOP00000001611.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-29	100.6	1339	1373
UBD/Beta-Prp	5.50e-44	150.9	1443	1656

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gHt  v c++ +d+ll +Gs D t+kvW+l tg  
   Q: 1339 GHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQE 1373
           899*****99767*****************99976 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee.. 131
           + e++++++ ++p+g +++ +++ ++++ wdl+ ++ + +l+gh   v++l++++  +g d +++Gs+d +i+++d+ +g       
   Q: 1443 SGENQINQIALNPTG-TFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQisNGqDLIITGSKDHYIKMFDVTEGALGTVsp 1528
           56789*********9.999*************************************9888*****************9998765467 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
              ++ +h + +  +++++  + l+sGs D+ ++ Wdl +++ll++   +h+d v  l + ++ + l+sg + g +k+w++ t   v
   Q: 1529 thnFEPPHYDGIEALTIQG--DNLFSGSRDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPV 1613
           7889999999999999999..7799**********************999************************************* PP
   S: 216  rtlnghtdnvksvrfspnderlvsgssDgsiriW...dlrsgdll 257
            +++gh+++++ + +   ++++ ++++D+++riW   +l+ g++ 
   Q: 1614 GEMKGHDSPINAICVN--STHIFTAADDRTVRIWkarNLQDGQIS 1656
           ***********99888..****************99999988876 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

SFLIISHRIR PQLAKEKIEG CHICTSVTPG EPQVFLGKDK AFTFDYVFDI DSQQEQIYIQ 60
CIEKLIEGCF EGYNATVFAY GQTGAGKTYT MGTGFDVNIV EEELGIISRA VKHLFKSIEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTTTTCTGA TTATTTCTCA CAGAATAAGA CCACAGCTTG CCAAAGAGAA GATTGAAGGA 60
TGCCATATTT GTACATCTGT CACACCAGGA GAGCCTCAGG TCTTCCTAGG GAAAGATAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	95.85	0.00e+00	3043.00
IUUC-Apl-003353	Anas platyrhynchos	84.43	0.00e+00	2657.00
IUUC-Aca-004467	Anolis carolinensis	84.04	0.00e+00	2721.00
IUUC-Bta-013485	Bos taurus	95.26	0.00e+00	2970.00
IUUC-Cel-018402	Caenorhabditis elegans	53.23	1.00e-147	518.00
IUUC-Cja-019385	Callithrix jacchus	96.05	0.00e+00	3033.00
IUUC-Cfa-020986	Canis familiaris	96.11	0.00e+00	3007.00
IUUC-Cpo-022297	Cavia porcellus	92.19	0.00e+00	2883.00
IUUC-Csa-023685	Chlorocebus sabaeus	97.42	0.00e+00	3066.00
IUUC-Cho-024531	Choloepus hoffmanni	92.58	0.00e+00	1092.00
IUUC-Cin-025160	Ciona intestinalis	47.35	2.00e-88	320.00
IUUC-Csv-026158	Ciona savignyi	57.99	2.00e-178	620.00
IUUC-Dre-028532	Danio rerio	67.34	0.00e+00	2113.00
IUUC-Dno-029972	Dasypus novemcinctus	91.72	0.00e+00	2800.00
IUUC-Ete-032872	Echinops telfairi	80.35	0.00e+00	1048.00
IUUC-Eca-033518	Equus caballus	95.91	0.00e+00	3019.00
IUUC-Fca-036197	Felis catus	95.97	0.00e+00	2993.00
IUUC-Fal-037534	Ficedula albicollis	84.29	0.00e+00	2652.00
IUUC-Gga-040687	Gallus gallus	83.23	0.00e+00	2607.00
IUUC-Gac-041626	Gasterosteus aculeatus	67.57	0.00e+00	2175.00
IUUC-Hsa-046372	Homo sapiens	99.28	0.00e+00	3100.00
IUUC-Lch-049786	Latimeria chalumnae	59.41	0.00e+00	1872.00
IUUC-Loc-052689	Lepisosteus oculatus	74.76	0.00e+00	2373.00
IUUC-Laf-054018	Loxodonta africana	89.91	0.00e+00	2775.00
IUUC-Mcc-055558	Macaca mulatta	98.26	0.00e+00	3079.00
IUUC-Meu-056080	Macropus eugenii	88.10	0.00e+00	987.00
IUUC-Mga-059283	Meleagris gallopavo	84.38	0.00e+00	2596.00
IUUC-Mmr-060773	Microcebus murinus	94.65	0.00e+00	2922.00
IUUC-Mdo-062688	Monodelphis domestica	89.84	0.00e+00	2628.00
IUUC-Mmu-063997	Mus musculus	92.50	0.00e+00	2860.00
IUUC-Mpu-066354	Mustela putorius furo	94.35	0.00e+00	2981.00
IUUC-Mlu-067599	Myotis lucifugus	95.33	0.00e+00	2968.00
IUUC-Nle-069477	Nomascus leucogenys	99.10	0.00e+00	3096.00
IUUC-Opr-070188	Ochotona princeps	80.94	0.00e+00	1794.00
IUUC-Ont-071938	Oreochromis niloticus	69.60	0.00e+00	2185.00
IUUC-Oan-073055	Ornithorhynchus anatinus	88.30	0.00e+00	2662.00
IUUC-Ocu-074302	Oryctolagus cuniculus	92.87	0.00e+00	2936.00
IUUC-Ola-087491	Oryzias latipes	63.79	0.00e+00	1881.00
IUUC-Oga-088799	Otolemur garnettii	94.95	0.00e+00	2718.00
IUUC-Oar-089629	Ovis aries	93.23	0.00e+00	2934.00
IUUC-Pan-092214	Papio anubis	96.81	0.00e+00	3051.00
IUUC-Psi-093757	Pelodiscus sinensis	81.95	0.00e+00	2529.00
IUUC-Pfo-097448	Poecilia formosa	61.73	0.00e+00	1909.00
IUUC-Pab-097984	Pongo abelii	98.62	0.00e+00	3047.00
IUUC-Pca-101061	Procavia capensis	77.68	0.00e+00	1755.00
IUUC-Pva-102306	Pteropus vampyrus	93.57	0.00e+00	2879.00
IUUC-Rno-105354	Rattus norvegicus	91.04	0.00e+00	2807.00
IUUC-Sha-106938	Sarcophilus harrisii	89.30	0.00e+00	1819.00
IUUC-Ssc-115810	Sus scrofa	95.14	0.00e+00	2949.00
IUUC-Tgu-117076	Taeniopygia guttata	82.25	0.00e+00	2526.00
IUUC-Tru-117904	Takifugu rubripes	62.76	0.00e+00	1956.00
IUUC-Tsy-119020	Tarsius syrichta	94.70	0.00e+00	2983.00
IUUC-Tni-120813	Tetraodon nigroviridis	66.57	0.00e+00	2112.00
IUUC-Tbe-127494	Tupaia belangeri	82.41	0.00e+00	1040.00
IUUC-Ttr-128393	Tursiops truncatus	87.89	0.00e+00	2712.00
IUUC-Vpa-130675	Vicugna pacos	82.11	0.00e+00	773.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence