iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132026

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAMC01148035

Gene Name

uba1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000010202.3	ENSXETT00000022524.3	ENSXETP00000022524.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	3.80e-155	517.3	53	427

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvn 89
           Y+R ++++G++a++++++++vl++G+ glG+E++Kn++l+Gv+s+t++D+   e+++l+ qF++r+ dvgk++Aev+  +l+eln +v 
   Q: 53   YSRPLYVLGHDAMKRMQNSNVLISGMSGLGVEIAKNIILGGVKSVTIHDQGNTEWADLSSQFYLREGDVGKNRAEVSHPRLAELNTYVP 141
           9**************************************************************************************** PP
   S: 90   veaheesiteleeeivFfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlke 178
           v++++ ++te+     F++ f++V+l+   +e++++v ++c+++++++i ++t+Gl+Gq+                       fc++++
   Q: 142  VSSSTGPLTED-----FLSAFQLVILTAATMEEQLRVGDFCHSHDIKFIVADTRGLFGQL-----------------------FCDFGK 202
           ***********.....********************************************.......................****** PP
   S: 179  tpnaaehtiewa..vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdiv 265
           ++ + +   e++  +++++++++++g +++l++ +++ +e+g+++++ e+++++e n++e++ei+v    +++i++++ ++++ +++iv
   Q: 203  EMVVMDPNGEQPlsAMISMITKDNPGVVTCLDE-ARHGFETGDFVTFTEVRGMTELNGCEPVEIKVLGPYTFSICDTSRFSDYVRGGIV 290
           ********************************8.69***************************************************** PP
   S: 266  tkskspfwvsfcsnaealqvpekvekdeevvkasaplylllralerfekkkgrkpgelsfekdddsavdlvtaaanlraeslgiep.kl 353
            ++k+p+ +sf+++ e+lq+p+  + d+++++++a+l+l ++ l++f+kk+g  p +   e d++++++l +++        ++++ ++
   Q: 291  AQVKMPKKISFKPLRESLQEPDFLVTDFAKFDHPAQLHLGFQGLHEFRKKHGHLP-KAHNEADAQEVLALTQTLN-EG-APGAVKQeEV 376
           ******************************************************9.8999999998888888766.33.455566667* PP
   S: 354  dddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfdae 404
           +++lik++a ++ +++a++na++gGlaaqE++K++sgkf+p+ ++++fda+
   Q: 377  KESLIKQLAYQARGNLAPINAFIGGLAAQEAMKACSGKFMPIMQWLYFDAL 427
           ************************************************986 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MSSSPLSKKR RVSGSETKTG SNCSSSNSVS TDQTAPANGM ARNGNSGLDE GLYSRPLYVL 60
GHDAMKRMQN SNVLISGMSG LGVEIAKNII LGGVKSVTIH DQGNTEWADL SSQFYLREGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCAGCT CGCCGCTGTC CAAGAAGCGT CGCGTGTCCG GATCTGAGAC AAAGACGGGT 60
TCAAACTGCT CATCCTCCAA CTCCGTGAGC ACCGATCAGA CTGCGCCGGC CAACGTGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0008641--F:small protein activating enzyme activity
GO:0007409--P:axonogenesis
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000456	Aegilops tauschii	39.94	0.00e+00	660.00
IUUC-Aml-001311	Ailuropoda melanoleuca	62.86	0.00e+00	1245.00
IUUC-Aca-004620	Anolis carolinensis	64.17	0.00e+00	1267.00
IUUC-Aly-005515	Arabidopsis lyrata	40.44	0.00e+00	665.00
IUUC-Ath-006891	Arabidopsis thaliana	40.84	0.00e+00	673.00
IUUC-Ago-007873	Ashbya gossypii	44.23	0.00e+00	727.00
IUUC-Acl-008181	Aspergillus clavatus	44.82	0.00e+00	762.00
IUUC-Afl-008455	Aspergillus flavus	45.98	0.00e+00	752.00
IUUC-Afu-009065	Aspergillus fumigatus	45.46	0.00e+00	784.00
IUUC-Ani-009371	Aspergillus nidulans	45.36	0.00e+00	745.00
IUUC-Ang-009737	Aspergillus niger	45.25	0.00e+00	766.00
IUUC-Aor-010007	Aspergillus oryzae	45.98	0.00e+00	751.00
IUUC-Ate-010466	Aspergillus terreus	45.55	0.00e+00	786.00
IUUC-Ame-010933	Astyanax mexicanus	64.76	0.00e+00	1221.00
IUUC-Bta-012767	Bos taurus	63.98	0.00e+00	1273.00
IUUC-Bci-013721	Botrytis cinerea	45.08	0.00e+00	754.00
IUUC-Bdi-014335	Brachypodium distachyon	39.37	0.00e+00	653.00
IUUC-Bol-015665	Brassica oleracea	39.50	0.00e+00	643.00
IUUC-Bra-017252	Brassica rapa	39.17	0.00e+00	661.00
IUUC-Cel-018260	Caenorhabditis elegans	40.82	0.00e+00	666.00
IUUC-Cja-019152	Callithrix jacchus	63.95	0.00e+00	1272.00
IUUC-Cfa-020622	Canis familiaris	62.14	0.00e+00	1198.00
IUUC-Cpo-022526	Cavia porcellus	63.79	0.00e+00	1251.00
IUUC-Csa-023780	Chlorocebus sabaeus	64.37	0.00e+00	1280.00
IUUC-Cin-025790	Ciona intestinalis	51.74	0.00e+00	950.00
IUUC-Csv-026084	Ciona savignyi	51.35	0.00e+00	954.00
IUUC-Dre-028149	Danio rerio	65.59	0.00e+00	1268.00
IUUC-Dno-028884	Dasypus novemcinctus	63.88	0.00e+00	1272.00
IUUC-Dor-030229	Dipodomys ordii	60.68	0.00e+00	1182.00
IUUC-Dse-031524	Dothistroma septosporum	44.96	0.00e+00	748.00
IUUC-Dme-032045	Drosophila melanogaster	49.13	0.00e+00	868.00
IUUC-Ete-032544	Echinops telfairi	67.17	0.00e+00	686.00
IUUC-Eca-033330	Equus caballus	63.88	0.00e+00	1271.00
IUUC-Fca-036255	Felis catus	64.08	0.00e+00	1263.00
IUUC-Fox-037796	Fusarium oxysporum	53.96	2.00e-119	422.00
IUUC-Gmo-039338	Gadus morhua	61.71	0.00e+00	1147.00
IUUC-Gga-040365	Gallus gallus	40.69	4.00e-166	578.00
IUUC-Gac-041773	Gasterosteus aculeatus	61.87	0.00e+00	1148.00
IUUC-Gma-043165	Glycine max	38.61	0.00e+00	640.00
IUUC-Ggo-045336	Gorilla gorilla	64.08	0.00e+00	1253.00
IUUC-Hsa-045982	Homo sapiens	64.08	0.00e+00	1250.00
IUUC-Hvu-047191	Hordeum vulgare	38.47	3.00e-176	612.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	64.17	0.00e+00	1273.00
IUUC-Kpa-049112	Komagataella pastoris	43.33	0.00e+00	706.00
IUUC-Lch-050371	Latimeria chalumnae	66.57	0.00e+00	1301.00
IUUC-Lpe-051520	Leersia perrieri	38.52	2.00e-175	609.00
IUUC-Loc-052936	Lepisosteus oculatus	66.15	0.00e+00	1293.00
IUUC-Laf-053948	Loxodonta africana	63.98	0.00e+00	1261.00
IUUC-Mcc-055843	Macaca mulatta	64.47	0.00e+00	1281.00
IUUC-Meu-056258	Macropus eugenii	64.41	0.00e+00	1268.00
IUUC-Mga-060052	Meleagris gallopavo	41.08	4.00e-143	501.00
IUUC-Mvi-060437	Microbotryum violaceum	45.84	0.00e+00	755.00
IUUC-Mmr-061405	Microcebus murinus	61.84	0.00e+00	1211.00
IUUC-Mdo-062032	Monodelphis domestica	62.39	0.00e+00	1223.00
IUUC-Mmu-063280	Mus musculus	64.07	0.00e+00	1252.00
IUUC-Mpu-066409	Mustela putorius furo	63.79	0.00e+00	1274.00
IUUC-Mlu-067217	Myotis lucifugus	63.48	0.00e+00	1264.00
IUUC-Nfi-068407	Neosartorya fischeri	45.36	0.00e+00	763.00
IUUC-Nle-070072	Nomascus leucogenys	60.56	0.00e+00	1144.00
IUUC-Opr-070715	Ochotona princeps	35.97	1.00e-145	510.00
IUUC-Ont-071671	Oreochromis niloticus	64.43	0.00e+00	1249.00
IUUC-Ocu-074544	Oryctolagus cuniculus	63.79	0.00e+00	1273.00
IUUC-Oba-075913	Oryza barthii	38.22	8.00e-175	607.00
IUUC-Ogl-077371	Oryza glaberrima	38.22	9.00e-175	607.00
IUUC-Ogu-078793	Oryza glumaepatula	38.22	9.00e-175	607.00
IUUC-Oin-079710	Oryza indica	38.22	3.00e-174	605.00
IUUC-Olo-080255	Oryza longistaminata	38.12	7.00e-174	604.00
IUUC-Ome-081171	Oryza meridionalis	38.12	3.00e-173	602.00
IUUC-Oni-082436	Oryza nivara	38.22	3.00e-174	605.00
IUUC-Opu-083161	Oryza punctata	38.03	7.00e-170	591.00
IUUC-Oru-085015	Oryza rufipogon	38.22	6.00e-175	608.00
IUUC-Osa-085455	Oryza sativa	38.22	7.00e-175	607.00
IUUC-Ola-087002	Oryzias latipes	63.84	0.00e+00	1234.00
IUUC-Oga-088594	Otolemur garnettii	64.56	0.00e+00	1251.00
IUUC-Oar-090068	Ovis aries	64.20	0.00e+00	1265.00
IUUC-Ptr-090581	Pan troglodytes	47.53	5.00e-139	488.00
IUUC-Pan-092114	Papio anubis	64.37	0.00e+00	1281.00
IUUC-Pma-094214	Petromyzon marinus	56.36	6.00e-50	189.00
IUUC-Pfo-097184	Poecilia formosa	64.36	0.00e+00	1247.00
IUUC-Pab-097861	Pongo abelii	63.98	0.00e+00	1243.00
IUUC-Pop-099550	Populus trichocarpa	39.26	0.00e+00	651.00
IUUC-Pca-100347	Procavia capensis	57.81	0.00e+00	936.00
IUUC-Ppe-102012	Prunus persica	39.54	0.00e+00	647.00
IUUC-Pva-102584	Pteropus vampyrus	64.37	0.00e+00	1269.00
IUUC-Pgr-103336	Puccinia graminis	48.25	0.00e+00	820.00
IUUC-Ptt-103939	Puccinia triticina	48.55	0.00e+00	827.00
IUUC-Rno-105462	Rattus norvegicus	63.97	0.00e+00	1253.00
IUUC-Sce-106245	Saccharomyces cerevisiae	42.64	0.00e+00	740.00
IUUC-Sha-107142	Sarcophilus harrisii	63.55	0.00e+00	1269.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	51.39	9.00e-175	607.00
IUUC-Sit-110294	Setaria italica	38.61	0.00e+00	631.00
IUUC-Stu-112109	Solanum tuberosum	39.48	0.00e+00	646.00
IUUC-Sar-113737	Sorex araneus	63.11	0.00e+00	1248.00
IUUC-Sbi-114774	Sorghum bicolor	39.05	0.00e+00	640.00
IUUC-Sre-115148	Sporisorium reilianum	45.93	0.00e+00	785.00
IUUC-Ssc-115777	Sus scrofa	63.82	0.00e+00	1263.00
IUUC-Tru-118742	Takifugu rubripes	64.24	0.00e+00	1199.00
IUUC-Tsy-119485	Tarsius syrichta	75.58	1.00e-133	469.00
IUUC-Tni-120401	Tetraodon nigroviridis	63.74	0.00e+00	1188.00
IUUC-Tca-121672	Theobroma cacao	39.92	0.00e+00	652.00
IUUC-Tae-125676	Triticum aestivum	38.69	3.00e-179	622.00
IUUC-Tur-126330	Triticum urartu	39.84	0.00e+00	660.00
IUUC-Tbe-127487	Tupaia belangeri	74.72	0.00e+00	809.00
IUUC-Ttr-128331	Tursiops truncatus	63.41	0.00e+00	1254.00
IUUC-Uma-129387	Ustilago maydis	45.31	0.00e+00	774.00
IUUC-Vpa-130801	Vicugna pacos	69.60	1.00e-126	446.00
IUUC-Xma-133805	Xiphophorus maculatus	63.91	0.00e+00	1222.00
IUUC-Yli-134547	Yarrowia lipolytica	44.85	0.00e+00	771.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence