iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLM	dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.50e-07	30.1	270	298

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 6    vtclaf.sd..tllvsGsdDgt.ikvWDl 30
            t +a+ ++  +ll++ ++D + i+++D+
   Q: 270  LTKVAWcPTrtGLLATLTRDSNiIRLYDM 298
           6789***444699*******88899***6 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSGTKPDILW APHQVDRFVV CDSELSLYHV ESAVNSELKA GSLRLSEDSA ATLLSINSDT 60
PYMKCVAWYL NYDPECLLAV GQANGRVVLT SLGQDHNSKF KDLIGKEFVP KHARQCNTLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGCAAACTT ACAGGTAAAT GAGAGACCCT TGCTTTTCCA TTGCTATATC CTGCTTCCTG 60
ACTCAGTATT TGCTCTTTTT CGGTGCTAGA AGGCTTTTCT CTTCCAATTG TTTCTGTCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR031488--Zn_ribbon_mio
IPR013083--Znf_RING/FYVE/PHD

Pfam

PF17034--zinc_ribbon_16

SMART

SM00320--WD40

Gene Ontology

GO:0061700--C:GATOR2 complex
GO:0005765--C:lysosomal membrane
GO:0034629--P:cellular protein complex localization
GO:0034198--P:cellular response to amino acid starvation
GO:0032008--P:positive regulation of TOR signaling

KEGG

rno:362324

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001544	Ailuropoda melanoleuca	98.29	0.00e+00	1805.00
IUUC-Apl-003888	Anas platyrhynchos	91.23	0.00e+00	1677.00
IUUC-Aca-004555	Anolis carolinensis	89.66	0.00e+00	1651.00
IUUC-Acl-008325	Aspergillus clavatus	29.53	1.00e-44	175.00
IUUC-Afl-008515	Aspergillus flavus	27.11	4.00e-47	183.00
IUUC-Afu-008938	Aspergillus fumigatus	27.60	5.00e-50	192.00
IUUC-Ani-009434	Aspergillus nidulans	27.52	2.00e-43	171.00
IUUC-Ang-009607	Aspergillus niger	27.75	9.00e-47	182.00
IUUC-Ate-010488	Aspergillus terreus	27.20	3.00e-45	177.00
IUUC-Ame-011575	Astyanax mexicanus	81.16	0.00e+00	1498.00
IUUC-Bta-012439	Bos taurus	97.49	0.00e+00	1798.00
IUUC-Cja-019416	Callithrix jacchus	97.94	0.00e+00	1801.00
IUUC-Cfa-020502	Canis familiaris	98.40	0.00e+00	1810.00
IUUC-Cpo-021505	Cavia porcellus	98.17	0.00e+00	1805.00
IUUC-Csa-023741	Chlorocebus sabaeus	98.06	0.00e+00	1804.00
IUUC-Cho-024318	Choloepus hoffmanni	92.74	0.00e+00	1131.00
IUUC-Cne-026795	Cryptococcus neoformans	27.87	4.00e-08	53.90
IUUC-Dre-028717	Danio rerio	79.79	0.00e+00	1238.00
IUUC-Dno-029671	Dasypus novemcinctus	97.60	0.00e+00	1797.00
IUUC-Dor-030959	Dipodomys ordii	98.40	0.00e+00	1808.00
IUUC-Dme-031859	Drosophila melanogaster	31.31	1.00e-112	400.00
IUUC-Ete-032566	Echinops telfairi	96.47	0.00e+00	1774.00
IUUC-Eca-033468	Equus caballus	98.17	0.00e+00	1803.00
IUUC-Eeu-034980	Erinaceus europaeus	93.83	0.00e+00	1706.00
IUUC-Fca-035591	Felis catus	98.51	0.00e+00	1811.00
IUUC-Fal-036655	Ficedula albicollis	91.59	0.00e+00	1686.00
IUUC-Gmo-039467	Gadus morhua	76.11	0.00e+00	1386.00
IUUC-Gac-041898	Gasterosteus aculeatus	79.84	0.00e+00	1456.00
IUUC-Ggo-045602	Gorilla gorilla	98.06	0.00e+00	1805.00
IUUC-Hsa-045989	Homo sapiens	98.06	0.00e+00	1804.00
IUUC-Itr-048336	Ictidomys tridecemlineatus	98.51	0.00e+00	1810.00
IUUC-Lch-049432	Latimeria chalumnae	87.56	0.00e+00	1615.00
IUUC-Loc-051863	Lepisosteus oculatus	83.47	0.00e+00	1508.00
IUUC-Laf-053630	Loxodonta africana	98.06	0.00e+00	1804.00
IUUC-Mcc-054913	Macaca mulatta	96.47	0.00e+00	1769.00
IUUC-Mla-058875	Melampsora laricipopulina	27.70	4.00e-30	127.00
IUUC-Mga-059331	Meleagris gallopavo	91.34	0.00e+00	1681.00
IUUC-Mvi-060377	Microbotryum violaceum	28.92	2.00e-42	167.00
IUUC-Mmr-061068	Microcebus murinus	97.83	0.00e+00	1797.00
IUUC-Mmu-064181	Mus musculus	99.43	0.00e+00	1819.00
IUUC-Mpu-065818	Mustela putorius furo	97.61	0.00e+00	1793.00
IUUC-Mlu-067027	Myotis lucifugus	97.61	0.00e+00	1795.00
IUUC-Nfi-068460	Neosartorya fischeri	27.80	7.00e-50	192.00
IUUC-Nle-069884	Nomascus leucogenys	97.83	0.00e+00	1800.00
IUUC-Opr-070764	Ochotona princeps	88.46	0.00e+00	1600.00
IUUC-Ont-071473	Oreochromis niloticus	80.27	0.00e+00	1462.00
IUUC-Ocu-074541	Oryctolagus cuniculus	97.60	0.00e+00	1791.00
IUUC-Ola-086342	Oryzias latipes	78.52	0.00e+00	1390.00
IUUC-Oga-089081	Otolemur garnettii	98.63	0.00e+00	1811.00
IUUC-Oar-089969	Ovis aries	97.83	0.00e+00	1800.00
IUUC-Ptr-091278	Pan troglodytes	98.06	0.00e+00	1804.00
IUUC-Pan-092315	Papio anubis	87.93	0.00e+00	1724.00
IUUC-Psi-093799	Pelodiscus sinensis	91.22	0.00e+00	1684.00
IUUC-Pno-094978	Phaeosphaeria nodorum	25.45	3.00e-22	100.00
IUUC-Pfo-096693	Poecilia formosa	80.41	0.00e+00	1453.00
IUUC-Pab-097903	Pongo abelii	98.06	0.00e+00	1804.00
IUUC-Pca-100325	Procavia capensis	98.03	0.00e+00	1031.00
IUUC-Pgr-103692	Puccinia graminis	27.37	4.00e-23	104.00
IUUC-Ptt-103704	Puccinia triticina	25.43	2.00e-08	54.70
IUUC-Spo-108350	Schizosaccharomyces pombe	33.58	2.00e-48	187.00
IUUC-Sar-113246	Sorex araneus	97.26	0.00e+00	1789.00
IUUC-Ssc-115759	Sus scrofa	98.13	0.00e+00	1645.00
IUUC-Tgu-116985	Taeniopygia guttata	91.13	0.00e+00	1674.00
IUUC-Tru-118524	Takifugu rubripes	79.84	0.00e+00	1466.00
IUUC-Tsy-119545	Tarsius syrichta	98.06	0.00e+00	1803.00
IUUC-Tni-120566	Tetraodon nigroviridis	78.56	0.00e+00	1440.00
IUUC-Tbe-127649	Tupaia belangeri	91.22	0.00e+00	1657.00
IUUC-Ttr-128308	Tursiops truncatus	98.28	0.00e+00	953.00
IUUC-Xtr-132955	Xenopus tropicalis	85.93	0.00e+00	1581.00
IUUC-Xma-133519	Xiphophorus maculatus	80.30	0.00e+00	1448.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence