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Tag Content
iUUCD ID IUUC-Fal-037179
Ensembl Protein ID ENSFALP00000000206.1
UniProt Accession U3JBQ2; U3JBQ2_FICAL
Genbank Protein ID ENSFALP00000000206
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID AGTO01021941
Gene Name KMT2D
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSFALG00000000182.1 ENSFALT00000000208.1 ENSFALP00000000206.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 1.20e-27 95.5 1378 1429
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCr 52
           vC++C+e++ +++ l++C++C++w+H+aC +l  eee+++  +  + C+ C+
   Q: 1378 VCPFCREKYVEDDLLIQCRHCDRWLHAACDSLFTEEEVEQAADegFDCSACQ 1429
           8*******************************9888888877678******7 PP
   
Organism Ficedula albicollis
Protein Sequence
(Fasta)
MDEEKVPSEE KDAAAPADGA MASEEMGSAE GDPLKPPEGA SAGPEPESRG MEGPPEAGSP 60
LGRRCALCNC GDWSLHGQRE LQRCEPVPDW PERLVGHEPP DGPGQPPPGP SQLPPEPELV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Fal-037179|E3,PHD|Ficedula albicollis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGACGAAG AGAAGGTGCC CAGCGAGGAG AAGGACGCAG CCGCGCCAGG TGAGCCAGGG 60
CAGGACTTTG GGGAGCTGTC CCTGTTTCCC CTGCGATGGT GACACCCCCT CTGCCCCCAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Fal-037179|E3,PHD|Ficedula albicollis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2
Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
SMART

SM00542--FYRC
SM00541--FYRN
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00184--RING
SM00317--SET
Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0008270--F:zinc ion binding
GO:0008284--P:positive regulation of cell proliferation
GO:0033148--P:positive regulation of intracellular estrogen receptor signaling pathway
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043627--P:response to estrogen
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001806 Ailuropoda melanoleuca 65.70 0.00e+00 1229.00
IUUC-Apl-003311 Anas platyrhynchos 73.54 0.00e+00 889.00
IUUC-Aca-005364 Anolis carolinensis 96.34 0.00e+00 1127.00
IUUC-Ame-010612 Astyanax mexicanus 80.66 0.00e+00 1010.00
IUUC-Bta-013011 Bos taurus 65.46 0.00e+00 1248.00
IUUC-Bra-017422 Brassica rapa 31.80 2.00e-26 114.00
IUUC-Cel-018354 Caenorhabditis elegans 36.75 3.00e-62 234.00
IUUC-Cja-019841 Callithrix jacchus 65.81 0.00e+00 1257.00
IUUC-Cfa-021131 Canis familiaris 66.05 0.00e+00 1233.00
IUUC-Cpo-021957 Cavia porcellus 65.65 0.00e+00 1298.00
IUUC-Csa-023722 Chlorocebus sabaeus 65.73 0.00e+00 1234.00
IUUC-Cho-024469 Choloepus hoffmanni 61.29 5.00e-95 344.00
IUUC-Dre-028110 Danio rerio 67.17 0.00e+00 835.00
IUUC-Dno-029932 Dasypus novemcinctus 65.54 0.00e+00 1178.00
IUUC-Dor-030192 Dipodomys ordii 66.57 0.00e+00 1043.00
IUUC-Dme-031590 Drosophila melanogaster 32.32 4.00e-60 227.00
IUUC-Ete-032572 Echinops telfairi 94.78 0.00e+00 942.00
IUUC-Eca-033945 Equus caballus 44.11 9.00e-165 576.00
IUUC-Eeu-034848 Erinaceus europaeus 67.89 0.00e+00 960.00
IUUC-Fca-035424 Felis catus 66.29 0.00e+00 1246.00
IUUC-Gmo-038719 Gadus morhua 82.81 0.00e+00 911.00
IUUC-Gga-040815 Gallus gallus 89.20 0.00e+00 1630.00
IUUC-Gac-042436 Gasterosteus aculeatus 80.04 0.00e+00 996.00
IUUC-Ggo-044711 Gorilla gorilla 65.97 0.00e+00 1245.00
IUUC-Hsa-046567 Homo sapiens 65.89 0.00e+00 1244.00
IUUC-Itr-048510 Ictidomys tridecemlineatus 65.16 0.00e+00 1241.00
IUUC-Lch-050086 Latimeria chalumnae 73.54 0.00e+00 885.00
IUUC-Loc-051979 Lepisosteus oculatus 82.59 0.00e+00 1065.00
IUUC-Laf-054377 Loxodonta africana 73.95 0.00e+00 1558.00
IUUC-Mcc-055577 Macaca mulatta 63.71 0.00e+00 1184.00
IUUC-Meu-055992 Macropus eugenii 94.48 0.00e+00 1080.00
IUUC-Mga-059541 Meleagris gallopavo 73.74 0.00e+00 730.00
IUUC-Mmr-061772 Microcebus murinus 64.35 0.00e+00 1254.00
IUUC-Mdo-062876 Monodelphis domestica 64.27 0.00e+00 780.00
IUUC-Mmu-063903 Mus musculus 64.34 0.00e+00 1204.00
IUUC-Mpu-066700 Mustela putorius furo 66.29 0.00e+00 1244.00
IUUC-Mlu-068180 Myotis lucifugus 66.29 0.00e+00 1260.00
IUUC-Nle-069362 Nomascus leucogenys 65.73 0.00e+00 1235.00
IUUC-Opr-070304 Ochotona princeps 80.88 0.00e+00 918.00
IUUC-Ont-071881 Oreochromis niloticus 62.66 0.00e+00 1360.00
IUUC-Oan-072945 Ornithorhynchus anatinus 73.54 0.00e+00 915.00
IUUC-Ocu-074053 Oryctolagus cuniculus 65.56 0.00e+00 1218.00
IUUC-Ola-086384 Oryzias latipes 53.41 0.00e+00 709.00
IUUC-Oga-088450 Otolemur garnettii 66.32 0.00e+00 1266.00
IUUC-Oar-089975 Ovis aries 63.48 0.00e+00 1149.00
IUUC-Ptr-091073 Pan troglodytes 65.89 0.00e+00 1244.00
IUUC-Pan-092871 Papio anubis 64.39 0.00e+00 1236.00
IUUC-Pma-094252 Petromyzon marinus 48.45 1.00e-98 355.00
IUUC-Pfo-097525 Poecilia formosa 80.66 0.00e+00 983.00
IUUC-Pab-097679 Pongo abelii 66.29 0.00e+00 1269.00
IUUC-Pca-100499 Procavia capensis 64.49 0.00e+00 1231.00
IUUC-Pva-102898 Pteropus vampyrus 66.32 0.00e+00 1257.00
IUUC-Rno-105660 Rattus norvegicus 64.44 0.00e+00 1209.00
IUUC-Sha-107431 Sarcophilus harrisii 66.10 0.00e+00 1201.00
IUUC-Sar-113183 Sorex araneus 75.00 1.00e-93 340.00
IUUC-Sbi-113816 Sorghum bicolor 33.04 2.00e-13 71.20
IUUC-Ssc-115678 Sus scrofa 65.35 0.00e+00 1222.00
IUUC-Tgu-116677 Taeniopygia guttata 75.73 0.00e+00 889.00
IUUC-Tru-117922 Takifugu rubripes 80.04 0.00e+00 1006.00
IUUC-Tsy-118932 Tarsius syrichta 72.85 0.00e+00 926.00
IUUC-Tni-119970 Tetraodon nigroviridis 57.46 0.00e+00 710.00
IUUC-Tur-126568 Triticum urartu 38.24 2.00e-11 64.70
IUUC-Tbe-127625 Tupaia belangeri 89.16 4.00e-133 471.00
IUUC-Ttr-129162 Tursiops truncatus 92.04 0.00e+00 1144.00
IUUC-Vpa-130236 Vicugna pacos 68.37 2.00e-85 312.00
IUUC-Xtr-132455 Xenopus tropicalis 64.71 0.00e+00 1319.00
Created Date 25-Jun-2017

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