iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053707

UUCD1 version

UUC-LoA-01101

Ensembl Protein ID

ENSLAFP00000018879.1

UniProt Accession

G3TTH1; G3TTH1_LOXAF

Protein Name

Uncharacterized protein

Gene Name

USP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000023157.2	ENSLAFT00000032437.1	ENSLAFP00000018879.1
ENSLAFG00000023157.2	ENSLAFT00000022591.2	ENSLAFP00000017441.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.70e-85	287.5	81	786

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle......kkkeklneenpkepkg..........ellkslqklfeel.......w..... 61
           +Gl+NlgNtCY+NS+LQ+L+++p +++ +++      +kke+l++e+++++kg          el++slq+l+ ++       +     
   Q: 81   VGLNNLGNTCYLNSILQVLYFCPGFKSGVKHlfnvisRKKEALKDEAHQKDKGncredslasyELICSLQSLIISVeqlqasfLlnpek 169
           6***********************************999999999999999999999******99999999999995555555144555 PP
   S: 62   kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsde.... 129
           ++++ a++pr+ll++l++++++++gy q+DaqE+l+++l +++e+++                  ek ++k e+++++++e++++    
   Q: 170  YTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLlkkeevknvaelytkveEKPHQKAEMSGTNNIEMDNMrhse 258
           88888*****************************************556667888888888887777777777777777777777**** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 259  eykeelpkgnakrksdtefgnmkkkskvskeyqsleenqrqtrskrkatgdmseipakilpkytcenesakpsqkksrvkinwlksatk 347
           ***************************************************************************************** PP
   S: 130  ...............................................................aeekkkkknk.....slisdlFqgql 150
                                                                          +e+k  +k+      +l+++lFqgql
   Q: 348  qpsilskfcslgkittnqgskgqfkeneydleedaekcengntlkvngcgldspgnnvkpinvNEDKAINKGVeqigfELVEKLFQGQL 436
           *******************************************************99999988555555555467888*********** PP
   S: 151  ksqikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeelegenkyycekckkkqeaekklklkk 225
             +++clec++ ++r+e+f+d+s+pv+++e +k e              +l++++++f++ e++ ge+ky+ce+c++++eae++l ++k
   Q: 437  VLRTRCLECESLTERRENFQDISVPVQEDELSKVEesseispepktemkTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDK 525
           ******************************99998****************************************************** PP
   S: 226  lPevLilhLkRf.......sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn..... 301
           +Pev+++hLk+f       +f+++++  +kin+ + +pl+L+l+++ t+p+     +++Y L+avv+HsG ++ssGHY+a vk      
   Q: 526  MPEVITIHLKCFaasgldpKFDCYGGGLSKINTPLLTPLKLSLEEWSTKPT-----NDSYGLFAVVMHSGiTISSGHYTASVKVtdlns 609
           *************************************************99.....678****************************** PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 610  leldtgnfmvdqicelgkpepsneeeargvaenydeeevsvrvsgntqpskvlnkknveaigllggqkskadyelynkasnpdkvagta 698
           ***************************************************************************************** PP
   S: 302  ..............................................ekgkWllfdDskVtevkeeevleetg......staYvlfYkr 337
                                                          +gkWllfdDs+V++++e+++l++ +      st+Y+lfYk+
   Q: 699  faesrnsetttngthesdnkessdetginisgfenkisyvvqslkeYEGKWLLFDDSEVKVTEEKDFLNSLSpstsptSTPYLLFYKK 786
           ***********999999999999999999999988888888877766999*******************888**************97 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MPGVIPSENN GLSRGSPSKK NRLSLKFFQK KETKRALDFT ESQENEEKVS EYNGTEIDQV 60
VPAAQSSPIN CEKRENLLPF VGLNNLGNTC YLNSILQVLY FCPGFKSGVK HLFNVISRKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTGGTG TCATACCTAG TGAAAACAAT GGGCTTTCAA GAGGTAGTCC ATCAAAGAAA 60
AACAGACTTT CCTTGAAGTT TTTTCAGAAA AAGGAAACTA AGAGAGCATT GGATTTCACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	90.51	0.00e+00	1375.00
IUUC-Apl-004204	Anas platyrhynchos	71.64	0.00e+00	921.00
IUUC-Aca-004637	Anolis carolinensis	64.93	0.00e+00	922.00
IUUC-Ame-011718	Astyanax mexicanus	47.73	5.00e-171	594.00
IUUC-Bta-012552	Bos taurus	88.72	0.00e+00	1350.00
IUUC-Cja-019588	Callithrix jacchus	90.62	0.00e+00	1410.00
IUUC-Cfa-020211	Canis familiaris	91.00	0.00e+00	1393.00
IUUC-Cpo-021551	Cavia porcellus	80.74	0.00e+00	1218.00
IUUC-Csa-024186	Chlorocebus sabaeus	90.49	0.00e+00	1407.00
IUUC-Cho-024739	Choloepus hoffmanni	82.54	0.00e+00	758.00
IUUC-Dre-028184	Danio rerio	48.78	9.00e-172	597.00
IUUC-Dno-029669	Dasypus novemcinctus	88.48	0.00e+00	1370.00
IUUC-Dor-030168	Dipodomys ordii	82.70	0.00e+00	1195.00
IUUC-Dme-031732	Drosophila melanogaster	27.88	2.00e-18	88.60
IUUC-Ete-032825	Echinops telfairi	88.58	0.00e+00	986.00
IUUC-Eca-033595	Equus caballus	90.03	0.00e+00	1300.00
IUUC-Eeu-034877	Erinaceus europaeus	77.56	2.00e-157	549.00
IUUC-Fca-035381	Felis catus	90.24	0.00e+00	979.00
IUUC-Fal-037592	Ficedula albicollis	68.96	0.00e+00	959.00
IUUC-Gmo-039680	Gadus morhua	44.76	8.00e-152	530.00
IUUC-Gga-041196	Gallus gallus	71.82	0.00e+00	1047.00
IUUC-Gac-042292	Gasterosteus aculeatus	48.59	3.00e-140	492.00
IUUC-Ggo-044671	Gorilla gorilla	90.75	0.00e+00	1415.00
IUUC-Hsa-047020	Homo sapiens	90.75	0.00e+00	1412.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	81.77	0.00e+00	1208.00
IUUC-Lch-050543	Latimeria chalumnae	57.61	0.00e+00	693.00
IUUC-Loc-052338	Lepisosteus oculatus	52.23	0.00e+00	681.00
IUUC-Mcc-055885	Macaca mulatta	90.87	0.00e+00	1413.00
IUUC-Meu-056573	Macropus eugenii	66.75	0.00e+00	942.00
IUUC-Mga-059346	Meleagris gallopavo	72.37	0.00e+00	1004.00
IUUC-Mmr-061612	Microcebus murinus	89.35	0.00e+00	1349.00
IUUC-Mdo-062887	Monodelphis domestica	72.29	0.00e+00	1038.00
IUUC-Mmu-064044	Mus musculus	84.81	0.00e+00	1312.00
IUUC-Mpu-066847	Mustela putorius furo	91.63	0.00e+00	1396.00
IUUC-Mlu-067684	Myotis lucifugus	89.25	0.00e+00	1382.00
IUUC-Nle-070057	Nomascus leucogenys	90.49	0.00e+00	1413.00
IUUC-Opr-070463	Ochotona princeps	80.20	0.00e+00	1193.00
IUUC-Ont-071975	Oreochromis niloticus	51.09	3.00e-139	489.00
IUUC-Oan-073062	Ornithorhynchus anatinus	86.73	3.00e-47	180.00
IUUC-Ocu-074840	Oryctolagus cuniculus	89.23	0.00e+00	1382.00
IUUC-Ola-087088	Oryzias latipes	47.15	6.00e-174	604.00
IUUC-Oga-088472	Otolemur garnettii	89.61	0.00e+00	1377.00
IUUC-Oar-089498	Ovis aries	88.72	0.00e+00	1350.00
IUUC-Ptr-091395	Pan troglodytes	90.87	0.00e+00	1414.00
IUUC-Pan-092462	Papio anubis	90.75	0.00e+00	1412.00
IUUC-Psi-093583	Pelodiscus sinensis	71.70	0.00e+00	899.00
IUUC-Pma-094644	Petromyzon marinus	35.54	1.00e-28	119.00
IUUC-Pfo-096314	Poecilia formosa	46.52	2.00e-167	583.00
IUUC-Pab-098568	Pongo abelii	91.25	0.00e+00	1422.00
IUUC-Pca-100948	Procavia capensis	85.15	0.00e+00	1310.00
IUUC-Pva-102853	Pteropus vampyrus	89.97	0.00e+00	1377.00
IUUC-Rno-105573	Rattus norvegicus	85.55	0.00e+00	1302.00
IUUC-Sha-107495	Sarcophilus harrisii	71.43	0.00e+00	873.00
IUUC-Sar-113545	Sorex araneus	75.13	0.00e+00	1070.00
IUUC-Ssc-115962	Sus scrofa	90.40	0.00e+00	1406.00
IUUC-Tgu-116731	Taeniopygia guttata	69.27	0.00e+00	977.00
IUUC-Tru-117893	Takifugu rubripes	44.99	5.00e-153	534.00
IUUC-Tsy-119644	Tarsius syrichta	80.84	0.00e+00	1198.00
IUUC-Tni-119819	Tetraodon nigroviridis	43.81	2.00e-166	579.00
IUUC-Tbe-127272	Tupaia belangeri	85.13	0.00e+00	1204.00
IUUC-Ttr-128404	Tursiops truncatus	90.23	0.00e+00	1389.00
IUUC-Vpa-130205	Vicugna pacos	89.21	0.00e+00	1375.00
IUUC-Xtr-132613	Xenopus tropicalis	53.96	0.00e+00	727.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence