iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Vda-129969

Ensembl Protein ID

EGY19927

UniProt Accession

G2WWF7; G2WWF7_VERDV

Genbank Protein ID

EGY19927.1

Protein Name

Ubiquitin-protein ligase E3A

Genbank Nucleotide ID

DS572697

Gene Name

VDAG_01943

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
VDAG_01943	EGY19927	EGY19927

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	8.90e-78	261.1	875	1219

Active Site

Position(s)	Description	Evidence
1188	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklll 101
           +d+kkrl++ef+gEeg d+gG+ +e++ ll++e++np+ glf+y+e+++ + + np+s+    e  + F ++G+++g+a++++ +ld+ l+++ y++ll
   Q: 875  EDIKKRLRIEFRGEEGYDAGGLRKEWFLLLVREVFNPEHGLFTYDEESQLC-YFNPNSF----ETSDQFFLVGVVIGLAIYNSTILDVALPPFAYRKLL 968
           689***************************************999977666.7799998....6889999****************************9 PP
   S: 102  gk................klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlke 184
                              ++ledl+e  p l+  lk+++++ + d+ee+ + l f v  e++g++ ++ L+pgGe  +Vtn+N++e+v+ +v y l  
   Q: 969  AAapissipssahprpvmTYNLEDLAEWRPRLAAGLKQLLDY-DGDVEET-FGLDFVVPVEKYGTVLQVPLCPGGEWKSVTNANRREFVDCYVRYLLDH 1065
           998877777777777666699*********************.6799987.************************************************ PP
   S: 185  gikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketky....kggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgG 278
            +++q+e f++Gf++v+  + lslF++ee+ell+ G+ + +d+++l++ ++y    +++   ++p+i wFw+++++ +  e++++L F+Tgs+r+P+ G
   Q: 1066 AVTRQFEPFKRGFYTVCGGNALSLFRPEEIELLVRGSdTALDIDSLRAAAEYdnwgTKNPDGTEPVIGWFWDTFKSAKPSEQRKLLSFITGSDRIPAMG 1164
           *************************************99*************877756677899*********************************** PP
   S: 279  faelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
            a l+ ++ ++ +  +++r+P + TCfn+L L +Y s+e l+++L +A++e++gF+l
   Q: 1165 AALLPIKISCLGE--DEERYPIARTCFNMLSLRRYGSQERLEHMLWTAVHESEGFGL 1219
           *****77666666..88**************************************98 PP

Organism

Verticillium dahliae

Protein Sequence
(Fasta)

MTSPWPPRRP PPPPPPRSPR RPAPQPSRRP SDDFVTRLHN TSLNAPPSEL ARLSRHDFAL 60
EDSQANADSS SSESDIHPSR PRRRPAHSRS MSVPFPSLFS SKKKQRPGPV HDDDSDDSHN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACATCTC CGTGGCCACC CCGACGTCCA CCACCTCCAC CGCCGCCCCG TTCGCCTCGA 60
CGACCTGCTC CCCAGCCCTC TCGACGTCCA TCCGACGACT TTGTCACCCG CCTGCACAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

vda:VDAG_01943

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	39.44	3.00e-99	353.00
IUUC-Atr-003144	Amborella trichopoda	38.00	1.00e-81	295.00
IUUC-Apl-003589	Anas platyrhynchos	37.85	2.00e-89	322.00
IUUC-Aca-004350	Anolis carolinensis	39.78	1.00e-93	335.00
IUUC-Ago-007908	Ashbya gossypii	32.02	2.00e-90	325.00
IUUC-Acl-008288	Aspergillus clavatus	44.16	0.00e+00	888.00
IUUC-Afl-008402	Aspergillus flavus	56.88	0.00e+00	707.00
IUUC-Afu-008762	Aspergillus fumigatus	45.06	0.00e+00	915.00
IUUC-Ani-009176	Aspergillus nidulans	40.96	0.00e+00	794.00
IUUC-Ang-009791	Aspergillus niger	46.34	0.00e+00	832.00
IUUC-Aor-009921	Aspergillus oryzae	60.80	0.00e+00	703.00
IUUC-Ate-010295	Aspergillus terreus	51.06	0.00e+00	822.00
IUUC-Ame-011166	Astyanax mexicanus	38.19	2.00e-85	308.00
IUUC-Bgr-011981	Blumeria graminis	47.97	0.00e+00	1018.00
IUUC-Bta-012945	Bos taurus	41.01	3.00e-98	351.00
IUUC-Bci-013697	Botrytis cinerea	54.56	0.00e+00	863.00
IUUC-Cel-018150	Caenorhabditis elegans	31.03	9.00e-56	210.00
IUUC-Cja-019263	Callithrix jacchus	41.23	4.00e-98	350.00
IUUC-Cfa-020486	Canis familiaris	39.44	6.00e-99	353.00
IUUC-Cpo-021755	Cavia porcellus	39.04	7.00e-99	353.00
IUUC-Cre-022740	Chlamydomonas reinhardtii	42.27	1.00e-62	231.00
IUUC-Csa-023378	Chlorocebus sabaeus	37.53	1.00e-81	296.00
IUUC-Cho-025059	Choloepus hoffmanni	35.02	8.00e-71	259.00
IUUC-Cin-025643	Ciona intestinalis	34.91	1.00e-66	246.00
IUUC-Csv-026282	Ciona savignyi	35.01	8.00e-61	226.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	58.56	0.00e+00	1205.00
IUUC-Cme-027151	Cyanidioschyzon merolae	37.77	2.00e-78	285.00
IUUC-Dre-028551	Danio rerio	41.59	7.00e-96	343.00
IUUC-Dno-029497	Dasypus novemcinctus	40.57	2.00e-97	348.00
IUUC-Dor-030158	Dipodomys ordii	34.11	4.00e-71	261.00
IUUC-Dse-031239	Dothistroma septosporum	48.16	0.00e+00	802.00
IUUC-Dme-032103	Drosophila melanogaster	34.88	8.00e-71	260.00
IUUC-Ete-032902	Echinops telfairi	36.25	2.00e-87	315.00
IUUC-Eca-033678	Equus caballus	39.64	2.00e-99	354.00
IUUC-Eeu-035109	Erinaceus europaeus	36.64	4.00e-73	267.00
IUUC-Fca-035590	Felis catus	39.64	1.00e-99	355.00
IUUC-Fal-036747	Ficedula albicollis	37.75	4.00e-82	297.00
IUUC-Fox-037941	Fusarium oxysporum	56.46	0.00e+00	1175.00
IUUC-Fso-038388	Fusarium solani	55.11	0.00e+00	1160.00
IUUC-Gmo-039553	Gadus morhua	40.18	6.00e-84	303.00
IUUC-Ggr-040110	Gaeumannomyces graminis	51.88	0.00e+00	1049.00
IUUC-Gga-040406	Gallus gallus	37.65	4.00e-93	333.00
IUUC-Gac-042141	Gasterosteus aculeatus	37.85	2.00e-92	331.00
IUUC-Ggo-045504	Gorilla gorilla	41.01	6.00e-98	350.00
IUUC-Hsa-045786	Homo sapiens	41.01	5.00e-98	350.00
IUUC-Itr-048289	Ictidomys tridecemlineatus	37.50	4.00e-79	287.00
IUUC-Kpa-049152	Komagataella pastoris	33.13	6.00e-92	330.00
IUUC-Lch-050197	Latimeria chalumnae	38.14	2.00e-85	308.00
IUUC-Loc-052173	Lepisosteus oculatus	34.65	3.00e-97	347.00
IUUC-Laf-054017	Loxodonta africana	40.00	1.00e-96	345.00
IUUC-Mcc-055713	Macaca mulatta	41.23	3.00e-98	351.00
IUUC-Meu-056061	Macropus eugenii	37.75	3.00e-80	291.00
IUUC-Mor-057045	Magnaporthe oryzae	51.44	0.00e+00	1077.00
IUUC-Mla-059187	Melampsora laricipopulina	44.00	2.00e-93	334.00
IUUC-Mga-059884	Meleagris gallopavo	40.24	1.00e-86	312.00
IUUC-Mmr-061344	Microcebus murinus	39.44	5.00e-100	357.00
IUUC-Mdo-062653	Monodelphis domestica	40.57	3.00e-96	344.00
IUUC-Mmu-063775	Mus musculus	41.23	2.00e-99	354.00
IUUC-Mpu-066069	Mustela putorius furo	39.64	2.00e-99	354.00
IUUC-Mlu-067925	Myotis lucifugus	41.23	3.00e-99	353.00
IUUC-Nfi-068439	Neosartorya fischeri	50.22	0.00e+00	838.00
IUUC-Ncr-068903	Neurospora crassa	53.50	0.00e+00	1016.00
IUUC-Nle-070046	Nomascus leucogenys	39.24	7.00e-99	353.00
IUUC-Opr-070570	Ochotona princeps	32.89	4.00e-61	228.00
IUUC-Ont-072126	Oreochromis niloticus	37.25	8.00e-92	329.00
IUUC-Oan-072933	Ornithorhynchus anatinus	40.31	2.00e-95	341.00
IUUC-Ocu-073800	Oryctolagus cuniculus	40.57	4.00e-97	347.00
IUUC-Ola-086988	Oryzias latipes	37.77	1.00e-91	328.00
IUUC-Oga-088117	Otolemur garnettii	40.35	7.00e-96	342.00
IUUC-Oar-089371	Ovis aries	41.01	8.00e-98	349.00
IUUC-Ptr-090551	Pan troglodytes	41.01	4.00e-98	350.00
IUUC-Pan-092067	Papio anubis	41.23	3.00e-98	351.00
IUUC-Psi-092963	Pelodiscus sinensis	40.92	1.00e-93	335.00
IUUC-Pma-094643	Petromyzon marinus	38.85	6.00e-84	303.00
IUUC-Ppa-095354	Physcomitrella patens	40.26	3.00e-90	324.00
IUUC-Pfo-096562	Poecilia formosa	37.13	9.00e-92	329.00
IUUC-Pab-098680	Pongo abelii	41.01	3.00e-98	350.00
IUUC-Pca-100869	Procavia capensis	36.87	1.00e-78	286.00
IUUC-Pva-102219	Pteropus vampyrus	38.73	7.00e-79	286.00
IUUC-Pgr-103315	Puccinia graminis	41.39	6.00e-99	353.00
IUUC-Ptt-103736	Puccinia triticina	42.35	4.00e-98	351.00
IUUC-Rno-105270	Rattus norvegicus	41.10	3.00e-99	354.00
IUUC-Sce-106306	Saccharomyces cerevisiae	33.08	5.00e-81	294.00
IUUC-Sha-106819	Sarcophilus harrisii	39.76	5.00e-100	356.00
IUUC-Sja-107974	Schizosaccharomyces japonicus	40.67	5.00e-54	203.00
IUUC-Spo-108271	Schizosaccharomyces pombe	37.30	1.00e-107	382.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	55.24	0.00e+00	889.00
IUUC-Smo-108858	Selaginella moellendorffii	39.87	2.00e-87	315.00
IUUC-Sar-113293	Sorex araneus	37.97	4.00e-82	297.00
IUUC-Ssc-115441	Sus scrofa	41.14	1.00e-98	352.00
IUUC-Tgu-117166	Taeniopygia guttata	38.25	3.00e-90	324.00
IUUC-Tru-118368	Takifugu rubripes	38.19	3.00e-84	304.00
IUUC-Tsy-118898	Tarsius syrichta	35.73	7.00e-77	280.00
IUUC-Tni-120143	Tetraodon nigroviridis	38.41	3.00e-84	305.00
IUUC-Tre-122108	Trichoderma reesei	52.27	0.00e+00	1042.00
IUUC-Tvi-122644	Trichoderma virens	51.96	0.00e+00	1054.00
IUUC-Tme-127004	Tuber melanosporum	45.21	0.00e+00	724.00
IUUC-Tbe-127640	Tupaia belangeri	38.68	2.00e-68	252.00
IUUC-Ttr-128352	Tursiops truncatus	38.46	1.00e-88	319.00
IUUC-Vpa-130448	Vicugna pacos	34.53	2.00e-71	262.00
IUUC-Xtr-132881	Xenopus tropicalis	37.75	4.00e-86	311.00
IUUC-Xma-133122	Xiphophorus maculatus	37.31	3.00e-83	301.00
IUUC-Yli-134470	Yarrowia lipolytica	37.88	3.00e-97	347.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence