iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067862

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02031230

Gene Name

UBA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000003047.2	ENSMLUT00000003051.2	ENSMLUP00000002773.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	5.90e-137	457.3	10	421

Active Site

Position(s)	Description	Evidence
173	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR039133-1, ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 11   eaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesite 99
           e  e++ + +vl+vGagg+GcEllKnLv +G+++i ++D dt++vsnlnrqFLf++++vg+sKA+va+e++ ++ p+ n+ a+++si++
   Q: 10   ELAEAVARGRVLVVGAGGIGCELLKNLVITGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIIAYHDSIMN 98
           6679999********************************************************************************** PP
   S: 100  leeeivFfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtie 188
           ++++++Ff++f +V++aldnr+ar++vnr+cl+a+vpliesgt G+lGqv++i kg+tecy+c+++p+q+t+P+ct+++tp+++ h+i+
   Q: 99   PDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIV 187
           ***************************************************************************************** PP
   S: 189  wa.vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv. 274
           wa +lfn+l++ee++++ev++  d++++e+++++ ++e++ ++++++ ++++i++k++ak+t ++ +k ++k f++di++  ++++++ 
   Q: 188  WAkYLFNQLFGEEDADQEVSP--DRADPEASWEPMEAEARVRASNEDGDIKRISTKEWAKSTGYDpVKLFTKLFKDDIRYLLTMDKLWr 274
           *********************..799*************************************************************** PP
   S: 275  .................sfcsnaealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekdddsavdlvtaaan 341
                            +  + a+++++p+ ++kd++v++++++     +++++++++++ek +g    el ++kdd+sa+d+vt+aan
   Q: 275  krkppvpldwaevqsqgEEINAADQQNEPQLGLKDQQVLDVKSYarlfsKSIETLRVHLAEKGDGA---ELIWDKDDPSAMDFVTSAAN 360
           *****************99***********************************************...68****************** PP
   S: 342  lraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfda 403
           lr++ +++++  ++++ik++agniipaiattnav++Gl+++E +K++sgk ++++++fl+++
   Q: 361  LRMHIFSMNM-KSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQ 421
           **********.***********************************************9965 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MALSRGLPRE LAEAVARGRV LVVGAGGIGC ELLKNLVITG FSHIDLIDLD TIDVSNLNRQ 60
FLFQKKHVGR SKAQVAKESV LQFYPKANII AYHDSIMNPD YNVEFFRQFI LVMNALDNRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCTGT CGCGGGGGCT CCCCCGAGAG CTGGCCGAGG CCGTGGCCAG GGGCCGGGTG 60
CTGGTGGTGG GCGCGGGCGG CATCGGCTGT GAGCTCCTCA AGAACCTCGT GATCACCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR030661--SAE2/Uba2
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR032426--UBA2_C
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF16195--UBA2_C

Gene Ontology

GO:0019948--F:SUMO activating enzyme activity
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	40.62	2.00e-107	383.00
IUUC-Aml-001662	Ailuropoda melanoleuca	97.35	0.00e+00	1251.00
IUUC-Atr-002636	Amborella trichopoda	40.33	4.00e-110	392.00
IUUC-Apl-003369	Anas platyrhynchos	89.39	0.00e+00	1029.00
IUUC-Aca-004490	Anolis carolinensis	82.80	0.00e+00	920.00
IUUC-Aly-006359	Arabidopsis lyrata	41.21	4.00e-103	368.00
IUUC-Ath-007667	Arabidopsis thaliana	41.76	2.00e-106	379.00
IUUC-Ago-007844	Ashbya gossypii	37.31	1.00e-84	306.00
IUUC-Acl-008270	Aspergillus clavatus	43.27	2.00e-105	376.00
IUUC-Afl-008674	Aspergillus flavus	42.35	1.00e-111	396.00
IUUC-Afu-008883	Aspergillus fumigatus	41.26	1.00e-106	380.00
IUUC-Ani-009500	Aspergillus nidulans	44.77	8.00e-116	410.00
IUUC-Ang-009535	Aspergillus niger	43.65	5.00e-111	395.00
IUUC-Aor-010223	Aspergillus oryzae	43.51	2.00e-113	403.00
IUUC-Ate-010282	Aspergillus terreus	43.45	3.00e-89	322.00
IUUC-Ame-011736	Astyanax mexicanus	77.32	0.00e+00	985.00
IUUC-Bgr-012166	Blumeria graminis	41.33	2.00e-97	349.00
IUUC-Bta-012589	Bos taurus	96.88	0.00e+00	1243.00
IUUC-Bci-013802	Botrytis cinerea	43.02	1.00e-100	360.00
IUUC-Bdi-014697	Brachypodium distachyon	41.76	2.00e-111	396.00
IUUC-Bol-016315	Brassica oleracea	39.14	2.00e-108	386.00
IUUC-Bra-017009	Brassica rapa	39.60	5.00e-109	388.00
IUUC-Cel-018708	Caenorhabditis elegans	46.48	3.00e-133	468.00
IUUC-Cja-019120	Callithrix jacchus	96.88	0.00e+00	1199.00
IUUC-Cfa-021061	Canis familiaris	97.82	0.00e+00	1252.00
IUUC-Cpo-021842	Cavia porcellus	95.94	0.00e+00	1194.00
IUUC-Csa-024104	Chlorocebus sabaeus	95.63	0.00e+00	1179.00
IUUC-Cho-024332	Choloepus hoffmanni	85.96	0.00e+00	871.00
IUUC-Cin-025363	Ciona intestinalis	61.50	0.00e+00	679.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	42.56	2.00e-99	356.00
IUUC-Cne-026888	Cryptococcus neoformans	52.69	2.00e-72	266.00
IUUC-Cme-027315	Cyanidioschyzon merolae	33.99	5.00e-59	222.00
IUUC-Dre-028420	Danio rerio	74.53	0.00e+00	919.00
IUUC-Dno-030041	Dasypus novemcinctus	97.35	0.00e+00	1212.00
IUUC-Dor-031039	Dipodomys ordii	81.56	0.00e+00	644.00
IUUC-Dse-031504	Dothistroma septosporum	42.99	8.00e-95	341.00
IUUC-Dme-031771	Drosophila melanogaster	49.34	2.00e-148	519.00
IUUC-Ete-033037	Echinops telfairi	90.64	0.00e+00	1075.00
IUUC-Eca-033774	Equus caballus	98.15	0.00e+00	1206.00
IUUC-Eeu-035074	Erinaceus europaeus	97.54	0.00e+00	981.00
IUUC-Fca-036508	Felis catus	98.49	0.00e+00	1209.00
IUUC-Fal-036813	Ficedula albicollis	86.66	0.00e+00	1021.00
IUUC-Fox-038056	Fusarium oxysporum	43.39	4.00e-105	375.00
IUUC-Fso-038223	Fusarium solani	43.09	2.00e-103	369.00
IUUC-Gmo-038526	Gadus morhua	74.57	0.00e+00	903.00
IUUC-Ggr-039767	Gaeumannomyces graminis	43.16	2.00e-99	357.00
IUUC-Gga-040981	Gallus gallus	88.40	0.00e+00	1058.00
IUUC-Gac-041437	Gasterosteus aculeatus	75.42	0.00e+00	922.00
IUUC-Gma-044072	Glycine max	37.48	2.00e-115	409.00
IUUC-Ggo-045358	Gorilla gorilla	92.26	0.00e+00	1123.00
IUUC-Hsa-046068	Homo sapiens	95.48	0.00e+00	1172.00
IUUC-Hvu-047646	Hordeum vulgare	38.19	7.00e-107	381.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	96.41	0.00e+00	1205.00
IUUC-Lch-049565	Latimeria chalumnae	81.06	0.00e+00	1032.00
IUUC-Lpe-050884	Leersia perrieri	41.01	7.00e-109	387.00
IUUC-Loc-052493	Lepisosteus oculatus	80.67	0.00e+00	1012.00
IUUC-Lma-053117	Leptosphaeria maculans	44.23	5.00e-102	365.00
IUUC-Laf-054518	Loxodonta africana	93.76	0.00e+00	1186.00
IUUC-Mcc-055334	Macaca mulatta	95.32	0.00e+00	1170.00
IUUC-Mor-057137	Magnaporthe oryzae	43.69	7.00e-95	341.00
IUUC-Mpo-057449	Magnaporthe poae	40.95	6.00e-101	361.00
IUUC-Mtr-058045	Medicago truncatula	39.31	1.00e-118	420.00
IUUC-Mla-058864	Melampsora laricipopulina	45.51	3.00e-96	345.00
IUUC-Mga-059422	Meleagris gallopavo	83.20	0.00e+00	934.00
IUUC-Mvi-060536	Microbotryum violaceum	42.44	2.00e-86	313.00
IUUC-Mmr-061161	Microcebus murinus	95.10	0.00e+00	1195.00
IUUC-Mdo-061802	Monodelphis domestica	92.68	0.00e+00	1140.00
IUUC-Mmu-064357	Mus musculus	93.45	0.00e+00	1188.00
IUUC-Mac-065475	Musa acuminata	38.87	2.00e-108	386.00
IUUC-Mpu-066895	Mustela putorius furo	97.97	0.00e+00	1251.00
IUUC-Nfi-068385	Neosartorya fischeri	43.44	6.00e-110	391.00
IUUC-Ncr-068885	Neurospora crassa	41.38	1.00e-106	380.00
IUUC-Nle-069524	Nomascus leucogenys	94.85	0.00e+00	1158.00
IUUC-Opr-071038	Ochotona princeps	96.10	0.00e+00	1234.00
IUUC-Ont-071719	Oreochromis niloticus	75.83	0.00e+00	981.00
IUUC-Oan-072877	Ornithorhynchus anatinus	89.06	0.00e+00	996.00
IUUC-Ocu-074080	Oryctolagus cuniculus	96.26	0.00e+00	1192.00
IUUC-Oba-075936	Oryza barthii	37.97	8.00e-109	387.00
IUUC-Obr-076841	Oryza brachyantha	38.45	2.00e-111	396.00
IUUC-Ogl-077686	Oryza glaberrima	38.03	3.00e-110	392.00
IUUC-Ogu-078597	Oryza glumaepatula	36.94	8.00e-106	377.00
IUUC-Oin-079791	Oryza indica	37.97	8.00e-109	387.00
IUUC-Olo-081009	Oryza longistaminata	37.82	3.00e-108	385.00
IUUC-Ome-081327	Oryza meridionalis	35.65	2.00e-103	369.00
IUUC-Oni-082334	Oryza nivara	37.27	3.00e-106	379.00
IUUC-Opu-083447	Oryza punctata	37.97	1.00e-109	390.00
IUUC-Oru-084977	Oryza rufipogon	38.13	9.00e-109	387.00
IUUC-Osa-086160	Oryza sativa	43.98	3.00e-95	341.00
IUUC-Ola-087415	Oryzias latipes	75.71	0.00e+00	946.00
IUUC-Olu-087850	Ostreococcus lucimarinus	40.78	6.00e-100	357.00
IUUC-Oga-088434	Otolemur garnettii	96.26	0.00e+00	1197.00
IUUC-Oar-089872	Ovis aries	97.31	0.00e+00	1202.00
IUUC-Ptr-091212	Pan troglodytes	95.48	0.00e+00	1172.00
IUUC-Pan-092708	Papio anubis	97.30	2.00e-132	465.00
IUUC-Psi-093703	Pelodiscus sinensis	90.91	0.00e+00	1058.00
IUUC-Pno-094953	Phaeosphaeria nodorum	46.06	9.00e-105	374.00
IUUC-Ppa-095963	Physcomitrella patens	44.09	2.00e-108	386.00
IUUC-Pfo-097515	Poecilia formosa	75.12	0.00e+00	934.00
IUUC-Pab-097951	Pongo abelii	95.05	0.00e+00	1016.00
IUUC-Pop-099703	Populus trichocarpa	34.90	2.00e-94	339.00
IUUC-Pca-100426	Procavia capensis	94.07	0.00e+00	1206.00
IUUC-Ppe-101152	Prunus persica	39.31	1.00e-111	396.00
IUUC-Pva-102792	Pteropus vampyrus	93.42	0.00e+00	1166.00
IUUC-Pgr-103592	Puccinia graminis	44.15	1.00e-100	360.00
IUUC-Ptt-103805	Puccinia triticina	41.70	4.00e-86	312.00
IUUC-Pte-104215	Pyrenophora teres	38.96	3.00e-113	402.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	38.46	5.00e-111	394.00
IUUC-Rno-106117	Rattus norvegicus	93.76	0.00e+00	1193.00
IUUC-Sce-106177	Saccharomyces cerevisiae	33.90	6.00e-76	278.00
IUUC-Sha-107006	Sarcophilus harrisii	92.85	0.00e+00	1142.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	44.19	9.00e-95	341.00
IUUC-Spo-108020	Schizosaccharomyces pombe	43.96	9.00e-96	344.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	44.02	1.00e-103	370.00
IUUC-Smo-109264	Selaginella moellendorffii	41.47	8.00e-109	387.00
IUUC-Sit-110581	Setaria italica	40.84	1.00e-109	390.00
IUUC-Sly-111870	Solanum lycopersicum	39.41	6.00e-111	394.00
IUUC-Stu-112283	Solanum tuberosum	39.54	6.00e-108	384.00
IUUC-Sar-113432	Sorex araneus	71.65	0.00e+00	793.00
IUUC-Sbi-114075	Sorghum bicolor	38.40	3.00e-109	389.00
IUUC-Sre-114926	Sporisorium reilianum	42.49	9.00e-103	367.00
IUUC-Ssc-116281	Sus scrofa	98.62	4.00e-118	417.00
IUUC-Tgu-117247	Taeniopygia guttata	85.55	0.00e+00	1018.00
IUUC-Tru-118075	Takifugu rubripes	71.52	0.00e+00	893.00
IUUC-Tsy-119398	Tarsius syrichta	80.62	0.00e+00	928.00
IUUC-Tni-120771	Tetraodon nigroviridis	65.64	0.00e+00	800.00
IUUC-Tca-121651	Theobroma cacao	40.36	2.00e-107	383.00
IUUC-Tre-122224	Trichoderma reesei	43.20	2.00e-96	347.00
IUUC-Tvi-122634	Trichoderma virens	42.70	8.00e-96	344.00
IUUC-Tae-125665	Triticum aestivum	40.75	6.00e-105	374.00
IUUC-Tur-126417	Triticum urartu	39.24	7.00e-106	377.00
IUUC-Tme-127016	Tuber melanosporum	44.81	1.00e-97	350.00
IUUC-Tbe-127678	Tupaia belangeri	81.77	9.00e-177	613.00
IUUC-Ttr-128598	Tursiops truncatus	93.45	0.00e+00	1187.00
IUUC-Uma-129612	Ustilago maydis	41.50	3.00e-97	349.00
IUUC-Vda-129811	Verticillium dahliae	39.87	2.00e-101	362.00
IUUC-Vpa-130732	Vicugna pacos	83.62	0.00e+00	1030.00
IUUC-Vvi-130832	Vitis vinifera	39.80	4.00e-107	382.00
IUUC-Xtr-132823	Xenopus tropicalis	76.00	0.00e+00	911.00
IUUC-Xma-133552	Xiphophorus maculatus	74.92	0.00e+00	931.00
IUUC-Yli-134666	Yarrowia lipolytica	37.66	2.00e-76	280.00
IUUC-Zma-135547	Zea mays	38.66	4.00e-108	385.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence