iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000008767.10	ENSDART00000149635.1	ENSDARP00000124214.1
ENSDARG00000008767.10	ENSDART00000105561.4	ENSDARP00000096338.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-23	82.9	610	648
UBD/Beta-Prp	2.30e-40	139.6	477	647

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t+++WDlr+g++l+
   Q: 610  GHTDGASCIDIsNDgTKLWTGGLDNTVRCWDLREGRQLQ 648
           8***********999*********************998 PP

UBD/Beta-Prp

   S: 48   lsgheaevtavkfspdgkilvtgseDrtikvwdls.....tgkcvhtlk..ghedsvlslsfspsgdklvsGshdrtirvwdletgqcl 129
           ls h + v av++s ++   v ++  + +kvwd+s     +  ++  l   + +++++s+++ p+g +l++G++ +t+ +wdl t +  
   Q: 477  LS-HGEVVCAVTISTSTR-HVYTGGKGCVKVWDISqpgskS--PMAQLDclNRDNYIRSCKILPDGRTLIVGGEASTLSIWDLATPTPR 561
           43.444788899999985.555555589*******776432..333333559*********************************9987 PP
   S: 130  ee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
            +  l+    +   ++++pd+++++s++ D+ + +Wdl +++l+r+++g htd   +++++ +g+ l +g+ld+tv+ wdl++g+ +
   Q: 562  IKaELTSSAPACYALAISPDNKVCFSCCSDGNIVVWDLHNQTLVRQFQG-HTDGASCIDISNDGTKLWTGGLDNTVRCWDLREGRQL 647
           765888888888899*********************************9.********************************99754 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MYPQGRHPVP LQPGQSFKFT VLETLDRIKE EFQFLQAQYH SLKLECEKLA SEKTEMQRHY 60
IMYYEMSYGL NIEMHKQAEI VKRLSAICAQ IIPFLSQEHQ QQVVQAVERA KQVTMAELNA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TACAGTGATA ACAAGAAATC GTATCATTGG TTGCACACAT GTATTGGTGT CTATTTCTGT 60
CTCTATCTTT CCGTCTATCT ATCCTCCATC TATCTCAGCC GGTCCACCTT AACTGCAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-010996	Astyanax mexicanus	91.95	0.00e+00	1236.00
IUUC-Cja-019135	Callithrix jacchus	69.62	0.00e+00	928.00
IUUC-Cpo-022495	Cavia porcellus	69.13	0.00e+00	923.00
IUUC-Csa-024056	Chlorocebus sabaeus	69.49	0.00e+00	934.00
IUUC-Eca-033351	Equus caballus	69.62	0.00e+00	928.00
IUUC-Gac-041949	Gasterosteus aculeatus	77.02	0.00e+00	939.00
IUUC-Mpu-065819	Mustela putorius furo	69.53	0.00e+00	940.00
IUUC-Opr-071172	Ochotona princeps	69.04	0.00e+00	915.00
IUUC-Ont-072426	Oreochromis niloticus	87.95	0.00e+00	1217.00
IUUC-Ola-087404	Oryzias latipes	83.73	0.00e+00	926.00
IUUC-Oar-089551	Ovis aries	69.41	0.00e+00	919.00
IUUC-Ptr-091207	Pan troglodytes	69.24	0.00e+00	929.00
IUUC-Pfo-096589	Poecilia formosa	80.36	0.00e+00	1026.00
IUUC-Tru-118327	Takifugu rubripes	84.64	0.00e+00	1157.00
IUUC-Tni-120016	Tetraodon nigroviridis	81.86	0.00e+00	1082.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence