iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-027031

Ensembl Protein ID

AAW44810

UniProt Accession

Q5KDD4; Q5KDD4_CRYNJ

Genbank Protein ID

AAW44810.1

Protein Name

WD repeat protein, putative

Genbank Nucleotide ID

AE017347

Gene Name

CNG04380

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNG04380	AAW44810	AAW44810

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.30e-32	106.2	480	511
UBD/Beta-Prp	1.00e-136	453.3	270	510

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gHt+++++laf ++ + l+s+s+D +i++W++
   Q: 480  GHTAPISGLAFsPTgNQLASSSWDRSIRLWSV 511
           8***********778***************96 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseD.rtikvwdlstgkcvhtlkghedsvlslsfspsgdkl 109
           ++vi+  +f+p++sll++g+ +g   +w++ + + +++ls  ++++++v  s +g++l+ g+   + + vw+ ++ ++v + +gh ++  +l+fsp+g+ +
   Q: 270  TKVIC-ATFHPKTSLLIVGFSSGVFGLWEMPEFTPVHTLSISNEKISSVAVSASGEWLAFGAAKlGQLLVWEWQSESYVLKQQGHYYDMNTLAFSPDGQNI 369
           44555.9*************************999***************************999************************************ PP
   S: 110  vsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldg.tvklwdl 209
           ++G++d  +++w+ ++g c+  t+ +h++++++v++ ++g++l+++slD+tvr +dl + +  rt+t+    +   l++d++g  + +gs+d+  + +w++
   Q: 370  ATGGEDGKVKLWNASSGFCFV-TFPEHTAAISTVEFAKQGQVLFTASLDGTVRAYDLIRYRNFRTFTSPTPVQFSALAVDPSGDVVCAGSQDSfEIYMWSV 469
           *********************.*********************************************98888888888**************956****** PP
   S: 210  qtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWd 250
           qtg+ +++l+ght++++ ++fsp ++ l+s s D+sir+W 
   Q: 470  QTGKLLDILTGHTAPISGLAFSPTGNQLASSSWDRSIRLWS 510
           ****************************************6 PP

Organism

Cryptococcus neoformans

Protein Sequence
(Fasta)

MKSNFVFQNL CGTVYRQGNV VFTPDGNSVL SPVGNRVSVF DLVNNKSRTL PFENRKNIAS 60
IALSPDGNVL ISIDEDGRAL FVHFRKGTVL HHISFKRKVH HVSFSPDGKY IAITHGHMVQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGTGGCAA TGAAGTCCAA CTTCGTCTTT CAAAATCTCT GCGGTACCGT TTACAGACAA 60
GGGAATGTTG TCTTTACGCC CGATGGGAAC TCTGTGTTGA GTCCGGTGGG AAACAGGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027145--PWP2
IPR011047--Quinoprotein_ADH-like_supfam
IPR007148--SSU_processome_Utp12
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04003--Utp12
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0030515--F:snoRNA binding
GO:0000920--P:cell separation after cytokinesis
GO:0000480--P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000447--P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472--P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0030010--P:establishment of cell polarity
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000028--P:ribosomal small subunit assembly

KEGG

cne:CNG04380

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001932	Ailuropoda melanoleuca	45.39	0.00e+00	805.00
IUUC-Atr-003033	Amborella trichopoda	40.88	0.00e+00	697.00
IUUC-Apl-003219	Anas platyrhynchos	45.03	0.00e+00	798.00
IUUC-Aca-004950	Anolis carolinensis	45.33	0.00e+00	822.00
IUUC-Aly-006213	Arabidopsis lyrata	41.63	0.00e+00	697.00
IUUC-Ath-006593	Arabidopsis thaliana	41.83	0.00e+00	702.00
IUUC-Ago-007916	Ashbya gossypii	49.00	0.00e+00	873.00
IUUC-Acl-008225	Aspergillus clavatus	51.71	0.00e+00	961.00
IUUC-Afl-008390	Aspergillus flavus	51.41	0.00e+00	961.00
IUUC-Afu-009039	Aspergillus fumigatus	50.39	0.00e+00	962.00
IUUC-Ani-009228	Aspergillus nidulans	44.25	0.00e+00	749.00
IUUC-Ang-009663	Aspergillus niger	50.51	0.00e+00	913.00
IUUC-Aor-009923	Aspergillus oryzae	51.41	0.00e+00	961.00
IUUC-Ate-010264	Aspergillus terreus	51.88	0.00e+00	955.00
IUUC-Ame-010790	Astyanax mexicanus	42.51	5.00e-93	332.00
IUUC-Bgr-012066	Blumeria graminis	50.69	0.00e+00	929.00
IUUC-Bta-012399	Bos taurus	46.07	0.00e+00	793.00
IUUC-Bci-013757	Botrytis cinerea	51.38	0.00e+00	918.00
IUUC-Bdi-015028	Brachypodium distachyon	44.42	0.00e+00	737.00
IUUC-Bol-016521	Brassica oleracea	41.67	0.00e+00	691.00
IUUC-Bra-017096	Brassica rapa	41.51	0.00e+00	693.00
IUUC-Cel-018690	Caenorhabditis elegans	35.67	8.00e-159	552.00
IUUC-Cja-019229	Callithrix jacchus	45.48	0.00e+00	796.00
IUUC-Cfa-020504	Canis familiaris	45.44	0.00e+00	796.00
IUUC-Cpo-021574	Cavia porcellus	46.47	0.00e+00	823.00
IUUC-Cre-022756	Chlamydomonas reinhardtii	43.94	1.00e-155	541.00
IUUC-Csa-023436	Chlorocebus sabaeus	45.34	0.00e+00	784.00
IUUC-Cin-025397	Ciona intestinalis	43.47	8.00e-177	612.00
IUUC-Csv-026194	Ciona savignyi	46.34	3.00e-144	504.00
IUUC-Cgl-026684	Colletotrichum gloeosporioides	49.08	0.00e+00	879.00
IUUC-Cme-027276	Cyanidioschyzon merolae	31.84	7.00e-121	426.00
IUUC-Dre-027514	Danio rerio	42.59	0.00e+00	762.00
IUUC-Dno-029191	Dasypus novemcinctus	44.22	0.00e+00	669.00
IUUC-Dor-030149	Dipodomys ordii	45.90	0.00e+00	808.00
IUUC-Dse-031260	Dothistroma septosporum	50.88	0.00e+00	625.00
IUUC-Dme-032043	Drosophila melanogaster	39.12	0.00e+00	698.00
IUUC-Ete-033102	Echinops telfairi	50.92	3.00e-163	566.00
IUUC-Eca-033223	Equus caballus	46.15	0.00e+00	814.00
IUUC-Fca-035795	Felis catus	44.53	0.00e+00	756.00
IUUC-Fal-036830	Ficedula albicollis	43.24	0.00e+00	789.00
IUUC-Fox-037835	Fusarium oxysporum	49.39	0.00e+00	902.00
IUUC-Fso-038324	Fusarium solani	49.09	0.00e+00	892.00
IUUC-Gmo-039355	Gadus morhua	43.57	0.00e+00	780.00
IUUC-Ggr-039840	Gaeumannomyces graminis	48.22	0.00e+00	839.00
IUUC-Gga-040907	Gallus gallus	49.15	2.00e-158	550.00
IUUC-Gac-042624	Gasterosteus aculeatus	43.50	0.00e+00	771.00
IUUC-Gma-043034	Glycine max	41.44	0.00e+00	745.00
IUUC-Hsa-046145	Homo sapiens	45.39	0.00e+00	805.00
IUUC-Hvu-047416	Hordeum vulgare	44.54	0.00e+00	745.00
IUUC-Itr-049083	Ictidomys tridecemlineatus	45.94	0.00e+00	815.00
IUUC-Kpa-049150	Komagataella pastoris	47.72	0.00e+00	862.00
IUUC-Lch-049460	Latimeria chalumnae	41.69	0.00e+00	664.00
IUUC-Lpe-050840	Leersia perrieri	42.97	0.00e+00	724.00
IUUC-Loc-052733	Lepisosteus oculatus	45.61	0.00e+00	815.00
IUUC-Lma-053277	Leptosphaeria maculans	49.83	0.00e+00	916.00
IUUC-Laf-054294	Loxodonta africana	46.60	0.00e+00	789.00
IUUC-Mcc-054624	Macaca mulatta	45.51	0.00e+00	805.00
IUUC-Meu-056665	Macropus eugenii	43.11	3.00e-96	343.00
IUUC-Mor-057288	Magnaporthe oryzae	47.93	0.00e+00	862.00
IUUC-Mpo-057594	Magnaporthe poae	48.85	0.00e+00	849.00
IUUC-Mtr-058700	Medicago truncatula	43.44	0.00e+00	773.00
IUUC-Mla-058846	Melampsora laricipopulina	56.74	0.00e+00	1054.00
IUUC-Mga-059207	Meleagris gallopavo	39.71	0.00e+00	669.00
IUUC-Mvi-060327	Microbotryum violaceum	63.90	0.00e+00	1158.00
IUUC-Mmr-061264	Microcebus murinus	45.95	0.00e+00	776.00
IUUC-Mdo-062327	Monodelphis domestica	45.79	0.00e+00	801.00
IUUC-Mmu-063542	Mus musculus	45.51	0.00e+00	795.00
IUUC-Mac-065142	Musa acuminata	43.07	0.00e+00	733.00
IUUC-Mpu-066098	Mustela putorius furo	44.05	0.00e+00	671.00
IUUC-Mlu-067056	Myotis lucifugus	42.30	0.00e+00	688.00
IUUC-Nfi-068323	Neosartorya fischeri	50.22	0.00e+00	967.00
IUUC-Ncr-068925	Neurospora crassa	50.69	0.00e+00	929.00
IUUC-Nle-068970	Nomascus leucogenys	45.11	0.00e+00	795.00
IUUC-Opr-070966	Ochotona princeps	56.79	3.00e-114	403.00
IUUC-Ont-071252	Oreochromis niloticus	43.23	0.00e+00	771.00
IUUC-Oan-072737	Ornithorhynchus anatinus	44.85	0.00e+00	785.00
IUUC-Oba-075794	Oryza barthii	42.54	0.00e+00	709.00
IUUC-Obr-076617	Oryza brachyantha	44.04	0.00e+00	746.00
IUUC-Ogl-077022	Oryza glaberrima	43.58	0.00e+00	747.00
IUUC-Ogu-078757	Oryza glumaepatula	35.67	5.00e-156	542.00
IUUC-Oin-079813	Oryza indica	43.35	0.00e+00	745.00
IUUC-Olo-080265	Oryza longistaminata	43.02	0.00e+00	741.00
IUUC-Ome-081494	Oryza meridionalis	43.46	0.00e+00	746.00
IUUC-Oni-082639	Oryza nivara	35.67	6.00e-156	542.00
IUUC-Opu-084005	Oryza punctata	43.51	0.00e+00	748.00
IUUC-Oru-084883	Oryza rufipogon	35.56	1.00e-155	541.00
IUUC-Osa-086158	Oryza sativa	43.46	0.00e+00	745.00
IUUC-Ola-086822	Oryzias latipes	45.34	0.00e+00	794.00
IUUC-Olu-087741	Ostreococcus lucimarinus	30.57	2.00e-20	89.70
IUUC-Oga-088887	Otolemur garnettii	45.67	0.00e+00	786.00
IUUC-Oar-090110	Ovis aries	44.43	0.00e+00	747.00
IUUC-Pan-092808	Papio anubis	46.25	0.00e+00	814.00
IUUC-Psi-093954	Pelodiscus sinensis	45.71	0.00e+00	816.00
IUUC-Pno-094922	Phaeosphaeria nodorum	50.63	0.00e+00	945.00
IUUC-Ppa-095678	Physcomitrella patens	43.87	0.00e+00	706.00
IUUC-Pfo-097175	Poecilia formosa	44.16	0.00e+00	801.00
IUUC-Pab-098155	Pongo abelii	45.43	0.00e+00	804.00
IUUC-Pop-099635	Populus trichocarpa	42.43	0.00e+00	743.00
IUUC-Pca-100947	Procavia capensis	42.74	0.00e+00	735.00
IUUC-Ppe-101552	Prunus persica	43.59	0.00e+00	764.00
IUUC-Pva-102744	Pteropus vampyrus	42.14	0.00e+00	686.00
IUUC-Pgr-103389	Puccinia graminis	56.52	0.00e+00	1030.00
IUUC-Ptt-103953	Puccinia triticina	48.22	0.00e+00	809.00
IUUC-Pte-104079	Pyrenophora teres	50.86	0.00e+00	936.00
IUUC-Pyt-104656	Pyrenophora triticirepentis	50.98	0.00e+00	931.00
IUUC-Rno-105502	Rattus norvegicus	45.40	0.00e+00	807.00
IUUC-Sce-106390	Saccharomyces cerevisiae	49.02	0.00e+00	897.00
IUUC-Sha-107264	Sarcophilus harrisii	41.12	3.00e-85	306.00
IUUC-Sja-107674	Schizosaccharomyces japonicus	50.11	0.00e+00	949.00
IUUC-Spo-108348	Schizosaccharomyces pombe	51.92	0.00e+00	959.00
IUUC-Smo-109327	Selaginella moellendorffii	41.55	0.00e+00	718.00
IUUC-Sit-110304	Setaria italica	43.66	0.00e+00	766.00
IUUC-Sly-111620	Solanum lycopersicum	46.03	7.00e-159	552.00
IUUC-Stu-112877	Solanum tuberosum	42.97	0.00e+00	773.00
IUUC-Sbi-114702	Sorghum bicolor	44.04	0.00e+00	750.00
IUUC-Sre-115129	Sporisorium reilianum	55.84	0.00e+00	1029.00
IUUC-Ssc-115931	Sus scrofa	42.08	2.00e-90	324.00
IUUC-Tgu-116787	Taeniopygia guttata	43.73	0.00e+00	792.00
IUUC-Tru-118218	Takifugu rubripes	45.45	0.00e+00	792.00
IUUC-Tsy-119401	Tarsius syrichta	45.04	1.00e-123	435.00
IUUC-Tni-120046	Tetraodon nigroviridis	44.69	0.00e+00	757.00
IUUC-Tca-121685	Theobroma cacao	42.02	0.00e+00	743.00
IUUC-Tre-122154	Trichoderma reesei	49.83	0.00e+00	920.00
IUUC-Tvi-122451	Trichoderma virens	49.26	0.00e+00	910.00
IUUC-Tae-125397	Triticum aestivum	44.58	4.00e-120	424.00
IUUC-Tur-126650	Triticum urartu	43.77	0.00e+00	679.00
IUUC-Tme-127005	Tuber melanosporum	53.88	0.00e+00	966.00
IUUC-Tbe-128102	Tupaia belangeri	47.05	1.00e-142	498.00
IUUC-Ttr-128259	Tursiops truncatus	46.82	0.00e+00	786.00
IUUC-Uma-129511	Ustilago maydis	56.43	0.00e+00	1011.00
IUUC-Vda-129833	Verticillium dahliae	46.64	0.00e+00	812.00
IUUC-Vvi-131572	Vitis vinifera	42.12	0.00e+00	706.00
IUUC-Xtr-131776	Xenopus tropicalis	31.28	1.00e-53	202.00
IUUC-Xma-133887	Xiphophorus maculatus	44.19	0.00e+00	776.00
IUUC-Yli-134427	Yarrowia lipolytica	48.49	0.00e+00	906.00
IUUC-Zma-135980	Zea mays	43.95	0.00e+00	738.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence