iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059340

UUCD1 version

UUC-MeG-00483

Ensembl Protein ID

ENSMGAP00000010789.1

UniProt Accession

G1ND89; G1ND89_MELGA

Protein Name

Uncharacterized protein

Gene Name

TRAF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000010397.1	ENSMGAT00000011654.1	ENSMGAP00000010789.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	4.60e-07	29.6	66	127

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrli 65
           + + CpI l   r+ v +p+G+ + + +I k +++ g++cPv+++ l e++l P ++ +r i
   Q: 66   SKYECPICLMALREAVQTPCGHRFCKGCIVKSIRDAGHKCPVDNEILLENQLFPDNFAKREI 127
           5689*****************************999999*****************999977 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MSLLHSDSSC GARDMDGGCC AAMASACSGG AKEDSVSVGS GTGNPPSSFT EETQGYDVEF 60
DPPLESKYEC PICLMALREA VQTPCGHRFC KGCIVKSIRD AGHKCPVDNE ILLENQLFPD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCTTGC TACACAGTGA TAGCAGCTGT GGGGCCCGAG ACATGGATGG CGGCTGCTGC 60
GCGGCCATGG CCAGCGCCTG CAGCGGGGGA GCAAAAGAAG ACAGTGTGAG CGTCGGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027139--TRAF6
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:0005811--C:lipid particle
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0043234--C:protein complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0009887--P:animal organ morphogenesis
GO:0019886--P:antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0045453--P:bone resorption
GO:0048468--P:cell development
GO:0071222--P:cellular response to lipopolysaccharide
GO:0007249--P:I-kappaB kinase/NF-kappaB signaling
GO:0070498--P:interleukin-1-mediated signaling pathway
GO:0043011--P:myeloid dendritic cell differentiation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0001843--P:neural tube closure
GO:0001503--P:ossification
GO:0030316--P:osteoclast differentiation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045084--P:positive regulation of interleukin-12 biosynthetic process
GO:0032743--P:positive regulation of interleukin-2 production
GO:0045410--P:positive regulation of interleukin-6 biosynthetic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0031666--P:positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0045672--P:positive regulation of osteoclast differentiation
GO:0002726--P:positive regulation of T cell cytokine production
GO:0042102--P:positive regulation of T cell proliferation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:2000679--P:positive regulation of transcription regulatory region DNA binding
GO:0051865--P:protein autoubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0051023--P:regulation of immunoglobulin secretion
GO:0050852--P:T cell receptor signaling pathway
GO:0042088--P:T-helper 1 type immune response

KEGG

mgp:100544809

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001262	Ailuropoda melanoleuca	74.86	0.00e+00	800.00
IUUC-Apl-004062	Anas platyrhynchos	95.83	0.00e+00	1100.00
IUUC-Aca-004636	Anolis carolinensis	77.19	0.00e+00	847.00
IUUC-Ame-011682	Astyanax mexicanus	54.70	9.00e-164	569.00
IUUC-Bta-012692	Bos taurus	74.18	0.00e+00	818.00
IUUC-Bci-013998	Botrytis cinerea	24.07	4.00e-14	72.40
IUUC-Cja-019426	Callithrix jacchus	72.66	0.00e+00	796.00
IUUC-Cfa-020948	Canis familiaris	74.44	0.00e+00	721.00
IUUC-Cpo-021378	Cavia porcellus	73.53	0.00e+00	801.00
IUUC-Csa-024045	Chlorocebus sabaeus	72.84	0.00e+00	814.00
IUUC-Cho-024973	Choloepus hoffmanni	61.00	5.00e-84	304.00
IUUC-Csv-026300	Ciona savignyi	41.27	9.00e-50	189.00
IUUC-Dre-027557	Danio rerio	58.87	3.00e-179	621.00
IUUC-Dno-030032	Dasypus novemcinctus	70.91	3.00e-122	431.00
IUUC-Dor-030790	Dipodomys ordii	73.39	0.00e+00	804.00
IUUC-Dme-031921	Drosophila melanogaster	27.43	2.00e-38	152.00
IUUC-Ete-032952	Echinops telfairi	70.85	4.00e-147	514.00
IUUC-Eca-033924	Equus caballus	70.57	0.00e+00	726.00
IUUC-Eeu-034734	Erinaceus europaeus	65.38	0.00e+00	688.00
IUUC-Fca-036222	Felis catus	69.91	0.00e+00	723.00
IUUC-Fal-036834	Ficedula albicollis	95.74	0.00e+00	950.00
IUUC-Fox-037935	Fusarium oxysporum	30.99	1.00e-22	100.00
IUUC-Gmo-039061	Gadus morhua	62.35	1.00e-89	323.00
IUUC-Ggr-040084	Gaeumannomyces graminis	25.40	1.00e-14	74.30
IUUC-Gga-040599	Gallus gallus	98.35	0.00e+00	1126.00
IUUC-Gac-041977	Gasterosteus aculeatus	59.52	3.00e-175	607.00
IUUC-Ggo-044508	Gorilla gorilla	68.19	0.00e+00	735.00
IUUC-Hsa-046349	Homo sapiens	72.84	0.00e+00	836.00
IUUC-Itr-047966	Ictidomys tridecemlineatus	72.84	0.00e+00	826.00
IUUC-Lch-049821	Latimeria chalumnae	70.79	0.00e+00	798.00
IUUC-Loc-051995	Lepisosteus oculatus	61.14	0.00e+00	644.00
IUUC-Laf-054115	Loxodonta africana	74.13	0.00e+00	820.00
IUUC-Mcc-055298	Macaca mulatta	72.48	0.00e+00	809.00
IUUC-Mor-057263	Magnaporthe oryzae	32.87	2.00e-20	93.60
IUUC-Mpo-057517	Magnaporthe poae	29.27	2.00e-16	80.50
IUUC-Mla-059039	Melampsora laricipopulina	48.00	3.00e-07	49.30
IUUC-Mvi-060553	Microbotryum violaceum	28.57	1.00e-17	84.30
IUUC-Mmr-061063	Microcebus murinus	74.35	0.00e+00	812.00
IUUC-Mdo-062075	Monodelphis domestica	74.13	0.00e+00	835.00
IUUC-Mmu-063780	Mus musculus	73.79	0.00e+00	781.00
IUUC-Mpu-065748	Mustela putorius furo	75.55	0.00e+00	816.00
IUUC-Mlu-067888	Myotis lucifugus	73.35	0.00e+00	802.00
IUUC-Ncr-068632	Neurospora crassa	25.23	5.00e-15	75.90
IUUC-Nle-069234	Nomascus leucogenys	72.66	0.00e+00	812.00
IUUC-Opr-070393	Ochotona princeps	79.81	3.00e-103	368.00
IUUC-Ont-072459	Oreochromis niloticus	55.99	0.00e+00	629.00
IUUC-Oan-073578	Ornithorhynchus anatinus	77.68	0.00e+00	865.00
IUUC-Ocu-074201	Oryctolagus cuniculus	73.59	0.00e+00	807.00
IUUC-Ome-081269	Oryza meridionalis	30.23	6.00e-08	51.20
IUUC-Ola-087319	Oryzias latipes	59.62	7.00e-91	327.00
IUUC-Oga-087936	Otolemur garnettii	72.66	0.00e+00	796.00
IUUC-Oar-089379	Ovis aries	74.50	0.00e+00	821.00
IUUC-Ptr-090758	Pan troglodytes	72.66	0.00e+00	811.00
IUUC-Pan-092590	Papio anubis	72.66	0.00e+00	810.00
IUUC-Psi-093948	Pelodiscus sinensis	83.91	0.00e+00	945.00
IUUC-Pma-094434	Petromyzon marinus	44.97	2.00e-130	459.00
IUUC-Pfo-096912	Poecilia formosa	58.80	5.00e-174	603.00
IUUC-Pab-097651	Pongo abelii	72.66	0.00e+00	813.00
IUUC-Pca-100958	Procavia capensis	70.96	2.00e-171	594.00
IUUC-Pva-103247	Pteropus vampyrus	75.40	5.00e-107	380.00
IUUC-Pte-104279	Pyrenophora teres	27.10	1.00e-14	74.70
IUUC-Pyt-104429	Pyrenophora triticirepentis	26.29	4.00e-14	72.00
IUUC-Rno-104994	Rattus norvegicus	74.12	0.00e+00	797.00
IUUC-Sha-106494	Sarcophilus harrisii	75.23	0.00e+00	850.00
IUUC-Ssl-108580	Sclerotinia sclerotiorum	24.38	5.00e-14	72.00
IUUC-Sar-113375	Sorex araneus	74.18	0.00e+00	802.00
IUUC-Sre-115218	Sporisorium reilianum	29.07	1.00e-17	85.10
IUUC-Ssc-115417	Sus scrofa	74.73	0.00e+00	821.00
IUUC-Tgu-117232	Taeniopygia guttata	93.20	0.00e+00	1018.00
IUUC-Tru-118321	Takifugu rubripes	57.92	7.00e-178	616.00
IUUC-Tni-120475	Tetraodon nigroviridis	55.94	2.00e-171	595.00
IUUC-Tur-126067	Triticum urartu	32.48	1.00e-08	53.50
IUUC-Tbe-127719	Tupaia belangeri	64.35	0.00e+00	676.00
IUUC-Ttr-129264	Tursiops truncatus	73.91	7.00e-104	370.00
IUUC-Uma-129620	Ustilago maydis	26.20	5.00e-16	79.30
IUUC-Vpa-130244	Vicugna pacos	76.68	1.00e-108	386.00
IUUC-Xtr-131948	Xenopus tropicalis	70.02	0.00e+00	785.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence