iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022508

Ensembl Protein ID

ENSCPOP00000010916.2

UniProt Accession

H0VKR6; H0VKR6_CAVPO

Genbank Protein ID

ENSCPOP00000010916

Protein Name

Small ubiquitin-related modifier

Genbank Nucleotide ID

AAKN02019435

Gene Name

SUMO1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000012143.3	ENSCPOT00000012259.2	ENSCPOP00000010916.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UBL/SUMO	3.00e-31	108.0	17	94
ULD/UDP/UBQ/UBQ_Other	5.50e-07	29.4	25	92

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UBL/SUMO

   S: 7    apvslkvagqdGsevlfklklsaqlkklmeavYvkrinldensvrfvfngqkireqetpeelevededkiellcqksGG 85
           ++++lkv gqd+se++fk+k++++lkkl+e+ Y++r+++ +ns+rf+f+gq+i++++tp+el++e+ed+ie++++++GG
   Q: 17   EYIKLKVIGQDSSEIHFKVKMTTHLKKLKES-YCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGG 94
           69*****************************.**********************************************9 PP

ULD/UDP/UBQ/UBQ_Other

   S: 7    sldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekks 74
             d+se  +kv+ ++  ++LKe   +++g+p+++ r +++G+ + d++t +++g+ ++++i +++++ 
   Q: 25   GQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQT 92
           455557778899999*************************************************9875 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

QEAKPSTEDL GDKKEGEYIK LKVIGQDSSE IHFKVKMTTH LKKLKESYCQ RQGVPMNSLR 60
FLFEGQRIAD NHTPKELGME EEDVIEVYQE QTGGHST 97

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGAGGCAA AACCTTCCAC TGAGGATTTG GGGGATAAGA AGGAAGGGGA ATATATTAAA 60
CTCAAAGTCA TTGGACAGGT GAGTGCTCTT ATTTCTCTGC TTTTACTTTT CCAATGTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR022617--Rad60/SUMO-like_dom
IPR033950--Sumo
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF11976--Rad60-SLD

SMART

SM00213--UBQ

Gene Ontology

GO:0031965--C:nuclear membrane
GO:0097165--C:nuclear stress granule
GO:0005730--C:nucleolus
GO:0016605--C:PML body
GO:0008076--C:voltage-gated potassium channel complex
GO:0001741--C:XY body
GO:0015459--F:potassium channel regulator activity
GO:0003723--F:RNA binding
GO:0008134--F:transcription factor binding
GO:0071276--P:cellular response to cadmium ion
GO:0034605--P:cellular response to heat
GO:0045759--P:negative regulation of action potential
GO:1902260--P:negative regulation of delayed rectifier potassium channel activity
GO:0043392--P:negative regulation of DNA binding
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0060021--P:palate development
GO:0030578--P:PML body organization
GO:1901896--P:positive regulation of calcium-transporting ATPase activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031334--P:positive regulation of protein complex assembly
GO:0090204--P:protein localization to nuclear pore
GO:0050821--P:protein stabilization
GO:0016925--P:protein sumoylation
GO:0086004--P:regulation of cardiac muscle cell contraction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001606	Ailuropoda melanoleuca	100.00	1.00e-53	200.00
IUUC-Apl-003638	Anas platyrhynchos	97.94	2.00e-52	196.00
IUUC-Aca-004710	Anolis carolinensis	98.95	5.00e-52	194.00
IUUC-Ago-007749	Ashbya gossypii	47.87	2.00e-18	82.80
IUUC-Ame-011662	Astyanax mexicanus	86.17	4.00e-43	165.00
IUUC-Bta-013491	Bos taurus	100.00	9.00e-54	201.00
IUUC-Cel-018251	Caenorhabditis elegans	65.82	1.00e-28	116.00
IUUC-Cja-019109	Callithrix jacchus	100.00	1.00e-53	200.00
IUUC-Cfa-020657	Canis familiaris	100.00	9.00e-54	201.00
IUUC-Cre-022970	Chlamydomonas reinhardtii	48.24	1.00e-19	87.00
IUUC-Csa-023026	Chlorocebus sabaeus	98.97	2.00e-43	166.00
IUUC-Cho-024767	Choloepus hoffmanni	100.00	2.00e-38	150.00
IUUC-Cne-027072	Cryptococcus neoformans	48.48	2.00e-14	70.10
IUUC-Dre-028383	Danio rerio	87.10	2.00e-42	162.00
IUUC-Dno-029820	Dasypus novemcinctus	100.00	9.00e-54	201.00
IUUC-Ete-032782	Echinops telfairi	75.00	2.00e-34	136.00
IUUC-Eca-033958	Equus caballus	100.00	9.00e-54	201.00
IUUC-Eeu-034822	Erinaceus europaeus	100.00	3.00e-53	199.00
IUUC-Fca-035601	Felis catus	100.00	1.00e-53	200.00
IUUC-Fal-036740	Ficedula albicollis	97.94	3.00e-52	196.00
IUUC-Gmo-038847	Gadus morhua	91.18	3.00e-33	132.00
IUUC-Gga-040129	Gallus gallus	97.94	1.00e-52	197.00
IUUC-Gac-042112	Gasterosteus aculeatus	88.17	6.00e-45	171.00
IUUC-Ggo-045413	Gorilla gorilla	100.00	9.00e-54	201.00
IUUC-Hsa-046108	Homo sapiens	100.00	9.00e-54	201.00
IUUC-Itr-047968	Ictidomys tridecemlineatus	100.00	1.00e-53	200.00
IUUC-Kpa-049243	Komagataella pastoris	46.81	4.00e-13	65.90
IUUC-Lch-049881	Latimeria chalumnae	84.04	2.00e-37	146.00
IUUC-Loc-052189	Lepisosteus oculatus	91.49	7.00e-48	181.00
IUUC-Laf-053478	Loxodonta africana	98.97	4.00e-53	198.00
IUUC-Mcc-055059	Macaca mulatta	65.31	1.00e-46	177.00
IUUC-Meu-056112	Macropus eugenii	96.91	5.00e-52	196.00
IUUC-Mla-059030	Melampsora laricipopulina	40.51	2.00e-07	47.80
IUUC-Mga-060035	Meleagris gallopavo	97.94	1.00e-52	196.00
IUUC-Mmr-060903	Microcebus murinus	100.00	9.00e-54	201.00
IUUC-Mdo-062633	Monodelphis domestica	96.91	3.00e-52	196.00
IUUC-Mmu-063272	Mus musculus	100.00	9.00e-54	201.00
IUUC-Mpu-066505	Mustela putorius furo	98.97	6.00e-53	198.00
IUUC-Mlu-067469	Myotis lucifugus	100.00	1.00e-53	200.00
IUUC-Nle-069344	Nomascus leucogenys	100.00	2.00e-39	152.00
IUUC-Opr-070351	Ochotona princeps	48.45	7.00e-16	76.30
IUUC-Ont-071436	Oreochromis niloticus	88.17	6.00e-45	171.00
IUUC-Oan-072986	Ornithorhynchus anatinus	98.08	3.00e-25	105.00
IUUC-Ocu-073781	Oryctolagus cuniculus	96.91	2.00e-51	193.00
IUUC-Ola-086373	Oryzias latipes	87.10	2.00e-43	166.00
IUUC-Olu-087670	Ostreococcus lucimarinus	44.29	2.00e-16	77.00
IUUC-Oga-088024	Otolemur garnettii	89.69	3.00e-48	182.00
IUUC-Oar-089991	Ovis aries	100.00	1.00e-53	200.00
IUUC-Ptr-090688	Pan troglodytes	97.94	1.00e-52	196.00
IUUC-Pan-092204	Papio anubis	100.00	9.00e-54	201.00
IUUC-Psi-093396	Pelodiscus sinensis	97.94	2.00e-52	196.00
IUUC-Pfo-096306	Poecilia formosa	86.46	3.00e-44	170.00
IUUC-Pab-098393	Pongo abelii	100.00	1.00e-53	202.00
IUUC-Pca-100237	Procavia capensis	98.97	1.00e-51	194.00
IUUC-Pva-102353	Pteropus vampyrus	100.00	3.00e-41	159.00
IUUC-Rno-105286	Rattus norvegicus	100.00	9.00e-54	201.00
IUUC-Sce-106231	Saccharomyces cerevisiae	47.92	5.00e-19	85.50
IUUC-Sha-106712	Sarcophilus harrisii	98.59	3.00e-38	149.00
IUUC-Sja-107710	Schizosaccharomyces japonicus	50.53	1.00e-21	94.70
IUUC-Spo-108261	Schizosaccharomyces pombe	52.13	5.00e-22	95.90
IUUC-Sit-110664	Setaria italica	30.86	8.00e-08	48.90
IUUC-Sar-113550	Sorex araneus	100.00	1.00e-52	196.00
IUUC-Sre-115172	Sporisorium reilianum	53.16	7.00e-20	87.80
IUUC-Ssc-115837	Sus scrofa	95.88	3.00e-52	196.00
IUUC-Tgu-117064	Taeniopygia guttata	97.92	4.00e-52	195.00
IUUC-Tru-117752	Takifugu rubripes	88.17	3.00e-45	172.00
IUUC-Tsy-119358	Tarsius syrichta	100.00	3.00e-40	156.00
IUUC-Tni-120621	Tetraodon nigroviridis	88.17	2.00e-44	170.00
IUUC-Tme-126902	Tuber melanosporum	45.68	1.00e-17	80.90
IUUC-Tbe-127355	Tupaia belangeri	75.00	2.00e-34	136.00
IUUC-Ttr-128166	Tursiops truncatus	98.97	1.00e-52	198.00
IUUC-Uma-129444	Ustilago maydis	53.16	2.00e-20	89.70
IUUC-Vpa-130172	Vicugna pacos	100.00	1.00e-53	201.00
IUUC-Xtr-132473	Xenopus tropicalis	93.88	2.00e-49	186.00
IUUC-Xma-133814	Xiphophorus maculatus	86.46	4.00e-45	172.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence