iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000018994.3	ENSMMUT00000055339.1	ENSMMUP00000050245.1
ENSMMUG00000018994.3	ENSMMUT00000026696.3	ENSMMUP00000024982.3
ENSMMUG00000018994.3	ENSMMUT00000062697.1	ENSMMUP00000055960.1
ENSMMUG00000018994.3	ENSMMUT00000062005.1	ENSMMUP00000049255.1
ENSMMUG00000018994.3	ENSMMUT00000066547.1	ENSMMUP00000055269.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.70e-41	140.6	49	180

Active Site

Position(s)	Description	Evidence
125	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 5    elkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWs 93
           el+e++k  +++++  +vde++l +w+ li+ p++ pY++g+F++ei+fp +YPfkPPk++f tki+hPn++e+G+vCl ++ ++e+W+
   Q: 49   ELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVI-SAENWK 135
           899999*************************.**************************************************.5***** PP
   S: 94   palsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           pa++  +v+ s+++l+++p+pe+pl+++ ae+++k+r+++ k+++
   Q: 136  PATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAE 180
           *****************************************9986 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MRVAAGARGD TRLQEVALLP QLFDLLVLGQ QRARLLRQVL GALAGKGLEL EEIRKCGMKN 60
FRNIQVDEAN LLTWQGLIVP DNPPYDKGAF RIEINFPAEY PFKPPKITFK TKIYHPNIDE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGGGTCG CTGCAGGGGC CCGAGGCGAC ACGCGCCTGC AGGAGGTGGC ACTCCTGCCG 60
CAGCTCTTCG ATCTGCTTGT CCTTGGCCAG CAGCGCGCTC GCCTGCTCCG ACAGGTCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001446	Ailuropoda melanoleuca	100.00	4.00e-53	199.00
IUUC-Apl-003318	Anas platyrhynchos	100.00	6.00e-73	265.00
IUUC-Aca-005234	Anolis carolinensis	100.00	3.00e-73	266.00
IUUC-Ame-011452	Astyanax mexicanus	95.17	1.00e-68	251.00
IUUC-Bta-012693	Bos taurus	100.00	6.00e-73	265.00
IUUC-Dno-029371	Dasypus novemcinctus	100.00	4.00e-55	206.00
IUUC-Eca-034188	Equus caballus	100.00	6.00e-73	265.00
IUUC-Fal-036820	Ficedula albicollis	99.32	2.00e-73	267.00
IUUC-Gmo-038480	Gadus morhua	91.03	2.00e-65	241.00
IUUC-Ggo-044482	Gorilla gorilla	100.00	5.00e-73	265.00
IUUC-Itr-049057	Ictidomys tridecemlineatus	100.00	2.00e-67	246.00
IUUC-Lch-049699	Latimeria chalumnae	81.90	5.00e-44	169.00
IUUC-Laf-053833	Loxodonta africana	100.00	9.00e-73	265.00
IUUC-Mmr-061002	Microcebus murinus	100.00	4.00e-72	263.00
IUUC-Mlu-066971	Myotis lucifugus	100.00	5.00e-73	265.00
IUUC-Nle-070093	Nomascus leucogenys	100.00	5.00e-73	265.00
IUUC-Oan-072711	Ornithorhynchus anatinus	100.00	2.00e-22	96.30
IUUC-Ocu-074565	Oryctolagus cuniculus	100.00	3.00e-73	266.00
IUUC-Ola-086994	Oryzias latipes	86.21	1.00e-72	265.00
IUUC-Oar-089520	Ovis aries	100.00	5.00e-73	265.00
IUUC-Pan-092445	Papio anubis	100.00	5.00e-73	265.00
IUUC-Psi-093376	Pelodiscus sinensis	100.00	8.00e-73	265.00
IUUC-Pva-103113	Pteropus vampyrus	100.00	6.00e-73	265.00
IUUC-Sha-106823	Sarcophilus harrisii	100.00	1.00e-70	258.00
IUUC-Sar-113240	Sorex araneus	100.00	6.00e-73	265.00
IUUC-Tgu-117352	Taeniopygia guttata	100.00	6.00e-73	265.00
IUUC-Tbe-127294	Tupaia belangeri	99.31	7.00e-72	262.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence