iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048306

Ensembl Protein ID

ENSSTOP00000017672.1

UniProt Accession

I3MZX6; I3MZX6_ICTTR

Genbank Protein ID

ENSSTOP00000017672

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01053909

Gene Name

USP15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000028998.1	ENSSTOT00000024593.1	ENSSTOP00000017672.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.30e-118	394.3	263	909
ULD/UDP/UBQ/UBQ_Other	3.40e-10	39.7	150	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS++QcLsn+p+l+e++l+ k++e+ln +np ++ ge++ks+++l++++w++k ++v+pr+++++++++a++fsgy+
   Q: 263  CGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNdKYQEELNFDNPLGMRGEIAKSYAELIKQMWSGKFSYVTPRAFKTQVGRFAPQFSGYQ 351
           7******************************9********************************************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD+qE+laflld+l+e+l++ ++kp+ +++++d   ++d+     a+e++ k+n+s+i+d+F+g +ks+++c+ec+++s++++pf++l
   Q: 352  QQDCQELLAFLLDGLHEDLNRIRKKPYIQLKDAD--GRPDKvvaeeAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFCYL 438
           ******************************9999..5555555777******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           +lp+p+k+e+ +e                                                                            
   Q: 439  TLPLPMKKERTLEvylvrmdpltkpmqykvvvpkignildlctalstlsgvpadkmivtdiynhrfhrifpmdenlssimerddiyvfe 527
           *********9999**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 528  ininrtedtehviipvclrekfrhssythhtgsslfgqpflmavprnntedklynllllrmcryvkisteteetegslhcckdqningn 616
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 617  gpngiheegspsemetdepddessqdqelpsenensqsedsvggdndsenglcteetckgqltghkkrlftfqfnnlgntdinyikddt 705
           ***************************************************************************************** PP
   S: 186  .......................................................slqdcLesftkeeelegenkyycekckkkqeaek 219
                                                                  +l+dc+e ft++e+l  e+ +yc++ck++q+a+k
   Q: 706  rhirfddrqlrldersflaldwdpelkkryfdenaaedfekhesvdykppkkpfvKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATK 794
           ***************************************************************************************** PP
   S: 220  klklkklPevLilhLkRfsfseeqksrekinkkvefp...leLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk 305
           kl+l++lP+vL++hLkRfs+s+  ++r k+++ v+fp     Ld+s+f+++p+ +   +++Y+Liav +H+G++++GHY+a++kn++++
   Q: 795  KLDLWSLPPVLVVHLKRFSYSR--YMRDKLDTLVDFPiknSDLDMSEFLINPNAG---PCRYNLIAVSNHYGGMGGGHYTAFAKNKDDG 878
           ******************9977..6999*********66444*********9988...8**************************6555 PP
   S: 306  .WllfdDskVtevkeeevleetgstaYvlfYkrr 338
            W++fdDs+V++ +e+++++   + aYvlfY+r+
   Q: 879  kWYYFDDSSVSTASEDQIVS---KAAYVLFYQRQ 909
           5*******************...*********96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgip.peqqrLiyk.....GkiL.eddktLadyglkdgstihllekksg 75
           + t++++++dt+ ++ ++i+k ++ip + + rL++k      ++L ++d t++d gl++g+++++++k+++
   Q: 150  VVTRRFSKADTIDTIEKEIRKIFNIPdEKETRLWNKymsntFEPLnKPDSTIQDAGLYQGQVLVIEQKNED 220
           77899*********************999*****998875544569*********************9986 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

WKKMAEGGAA DLDTQRSDIA TLLKTSLRKG DTWYLVDSRW FKQWKKYVGF DSWDKYQMGD 60
QNVYPGPIDN SGLLKDGDAQ SLKEHLIDEL DYILLPTEGW NKLVSWYTLM EGQEPIARKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCCGCCGC CGTAGCTGCC GCCTCCGCTG CCGCTAGTGG AAGAAGATGG CGGAAGGCGG 60
AGCGGCGGAC CTGGACACCC AGCGTTCTGA CATCGCGACG CTGCTGAAAA CCTCGCTCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR013792--RNA3'P_cycl/enolpyr_Trfase_a/b
IPR028135--Ub_USP-typ
IPR029071--Ubiquitin-rel_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0030509--P:BMP signaling pathway
GO:0035616--P:histone H2B conserved C-terminal lysine deubiquitination
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0060389--P:pathway-restricted SMAD protein phosphorylation
GO:0007179--P:transforming growth factor beta receptor signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000058	Aegilops tauschii	36.98	3.00e-118	419.00
IUUC-Aml-001852	Ailuropoda melanoleuca	95.22	0.00e+00	1852.00
IUUC-Apl-003249	Anas platyrhynchos	92.45	0.00e+00	1681.00
IUUC-Aca-004261	Anolis carolinensis	91.29	0.00e+00	1703.00
IUUC-Aly-005644	Arabidopsis lyrata	35.35	2.00e-138	486.00
IUUC-Ath-006782	Arabidopsis thaliana	35.15	3.00e-138	485.00
IUUC-Acl-008284	Aspergillus clavatus	33.86	5.00e-56	213.00
IUUC-Afl-008507	Aspergillus flavus	38.57	5.00e-55	209.00
IUUC-Afu-008878	Aspergillus fumigatus	33.74	5.00e-56	213.00
IUUC-Ani-009479	Aspergillus nidulans	42.91	9.00e-52	199.00
IUUC-Aor-009949	Aspergillus oryzae	38.29	6.00e-54	206.00
IUUC-Ame-010757	Astyanax mexicanus	77.74	0.00e+00	1232.00
IUUC-Bgr-012277	Blumeria graminis	43.11	4.00e-64	240.00
IUUC-Bta-013128	Bos taurus	98.32	0.00e+00	1874.00
IUUC-Bci-013993	Botrytis cinerea	43.25	6.00e-64	239.00
IUUC-Bol-015570	Brassica oleracea	37.39	1.00e-152	533.00
IUUC-Bra-017029	Brassica rapa	36.45	3.00e-139	489.00
IUUC-Cja-019222	Callithrix jacchus	95.12	0.00e+00	1850.00
IUUC-Cfa-020035	Canis familiaris	95.22	0.00e+00	1850.00
IUUC-Cpo-022071	Cavia porcellus	94.91	0.00e+00	1766.00
IUUC-Csa-023882	Chlorocebus sabaeus	95.42	0.00e+00	1855.00
IUUC-Cin-025292	Ciona intestinalis	44.75	0.00e+00	744.00
IUUC-Csv-026109	Ciona savignyi	43.05	0.00e+00	686.00
IUUC-Cgl-026741	Colletotrichum gloeosporioides	36.42	7.00e-61	229.00
IUUC-Cme-027338	Cyanidioschyzon merolae	56.36	4.00e-68	252.00
IUUC-Dre-027869	Danio rerio	58.23	0.00e+00	1079.00
IUUC-Dno-029025	Dasypus novemcinctus	95.47	0.00e+00	1790.00
IUUC-Dor-030956	Dipodomys ordii	85.82	0.00e+00	1578.00
IUUC-Dse-031432	Dothistroma septosporum	40.07	1.00e-57	219.00
IUUC-Eca-034340	Equus caballus	95.28	0.00e+00	1796.00
IUUC-Eeu-034488	Erinaceus europaeus	84.47	0.00e+00	1229.00
IUUC-Fca-035552	Felis catus	98.53	0.00e+00	1870.00
IUUC-Fal-036618	Ficedula albicollis	92.24	0.00e+00	1673.00
IUUC-Gga-041146	Gallus gallus	91.16	0.00e+00	1716.00
IUUC-Gac-041679	Gasterosteus aculeatus	76.26	0.00e+00	1439.00
IUUC-Gma-042669	Glycine max	40.94	4.00e-117	416.00
IUUC-Ggo-045002	Gorilla gorilla	95.07	0.00e+00	1788.00
IUUC-Hsa-046052	Homo sapiens	95.32	0.00e+00	1854.00
IUUC-Hvu-047108	Hordeum vulgare	40.27	1.00e-121	429.00
IUUC-Kpa-049332	Komagataella pastoris	33.83	5.00e-75	276.00
IUUC-Lch-050107	Latimeria chalumnae	84.26	0.00e+00	1700.00
IUUC-Loc-052105	Lepisosteus oculatus	81.44	0.00e+00	1484.00
IUUC-Lma-052981	Leptosphaeria maculans	37.50	3.00e-67	251.00
IUUC-Laf-053645	Loxodonta africana	94.82	0.00e+00	1847.00
IUUC-Mcc-055586	Macaca mulatta	95.32	0.00e+00	1854.00
IUUC-Meu-056764	Macropus eugenii	90.19	0.00e+00	1001.00
IUUC-Mga-060162	Meleagris gallopavo	91.46	0.00e+00	1721.00
IUUC-Mvi-060324	Microbotryum violaceum	32.11	1.00e-80	295.00
IUUC-Mmr-061105	Microcebus murinus	95.52	0.00e+00	1855.00
IUUC-Mdo-062107	Monodelphis domestica	93.60	0.00e+00	1799.00
IUUC-Mmu-063662	Mus musculus	93.90	0.00e+00	1832.00
IUUC-Mpu-065868	Mustela putorius furo	93.32	0.00e+00	1842.00
IUUC-Mlu-068000	Myotis lucifugus	90.01	0.00e+00	1670.00
IUUC-Nfi-068330	Neosartorya fischeri	28.49	2.00e-58	221.00
IUUC-Ncr-068879	Neurospora crassa	40.00	1.00e-61	231.00
IUUC-Nle-069874	Nomascus leucogenys	95.16	0.00e+00	1828.00
IUUC-Opr-071212	Ochotona princeps	89.56	0.00e+00	1734.00
IUUC-Ont-071834	Oreochromis niloticus	77.94	0.00e+00	1432.00
IUUC-Ocu-074573	Oryctolagus cuniculus	95.42	0.00e+00	1855.00
IUUC-Obr-076416	Oryza brachyantha	39.78	7.00e-118	417.00
IUUC-Ola-086553	Oryzias latipes	58.47	0.00e+00	1090.00
IUUC-Oga-089022	Otolemur garnettii	98.01	0.00e+00	1875.00
IUUC-Oar-089767	Ovis aries	94.81	0.00e+00	1847.00
IUUC-Ptr-091319	Pan troglodytes	98.95	0.00e+00	1883.00
IUUC-Pan-091968	Papio anubis	95.42	0.00e+00	1855.00
IUUC-Psi-093849	Pelodiscus sinensis	91.19	0.00e+00	1675.00
IUUC-Pma-094533	Petromyzon marinus	60.66	0.00e+00	1118.00
IUUC-Pno-094890	Phaeosphaeria nodorum	37.68	1.00e-61	231.00
IUUC-Pfo-097110	Poecilia formosa	76.65	0.00e+00	1429.00
IUUC-Pab-098664	Pongo abelii	95.42	0.00e+00	1855.00
IUUC-Pop-099801	Populus trichocarpa	37.25	2.00e-151	530.00
IUUC-Pca-100359	Procavia capensis	85.63	0.00e+00	1090.00
IUUC-Ppe-101587	Prunus persica	37.54	6.00e-149	521.00
IUUC-Pva-102394	Pteropus vampyrus	93.29	0.00e+00	1805.00
IUUC-Pgr-103546	Puccinia graminis	29.52	2.00e-67	251.00
IUUC-Pte-104102	Pyrenophora teres	37.61	8.00e-59	223.00
IUUC-Pyt-104812	Pyrenophora triticirepentis	41.47	6.00e-58	219.00
IUUC-Rno-105383	Rattus norvegicus	98.01	0.00e+00	1872.00
IUUC-Sce-106170	Saccharomyces cerevisiae	36.97	2.00e-60	227.00
IUUC-Sha-107393	Sarcophilus harrisii	93.71	0.00e+00	1808.00
IUUC-Sja-107752	Schizosaccharomyces japonicus	36.01	1.00e-84	307.00
IUUC-Spo-108291	Schizosaccharomyces pombe	33.05	3.00e-77	283.00
IUUC-Ssl-108461	Sclerotinia sclerotiorum	30.56	1.00e-13	71.60
IUUC-Smo-109356	Selaginella moellendorffii	46.85	4.00e-79	288.00
IUUC-Sly-111726	Solanum lycopersicum	38.38	4.00e-94	338.00
IUUC-Sar-113498	Sorex araneus	94.91	0.00e+00	1844.00
IUUC-Ssc-115285	Sus scrofa	95.43	0.00e+00	1854.00
IUUC-Tgu-116529	Taeniopygia guttata	91.97	0.00e+00	1733.00
IUUC-Tru-118298	Takifugu rubripes	77.20	0.00e+00	1444.00
IUUC-Tsy-119117	Tarsius syrichta	89.23	0.00e+00	1148.00
IUUC-Tni-120093	Tetraodon nigroviridis	73.76	0.00e+00	1373.00
IUUC-Tre-121888	Trichoderma reesei	42.45	8.00e-63	236.00
IUUC-Tvi-122422	Trichoderma virens	39.93	4.00e-57	217.00
IUUC-Tae-125811	Triticum aestivum	37.59	5.00e-125	441.00
IUUC-Tur-126149	Triticum urartu	36.88	2.00e-104	374.00
IUUC-Tbe-127672	Tupaia belangeri	86.96	0.00e+00	1217.00
IUUC-Ttr-128441	Tursiops truncatus	88.76	0.00e+00	1118.00
IUUC-Vpa-130469	Vicugna pacos	94.86	0.00e+00	1778.00
IUUC-Xtr-132729	Xenopus tropicalis	81.50	0.00e+00	1594.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence