iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000008808.9	ENSDART00000155154.2	ENSDARP00000129034.1
ENSDARG00000008808.9	ENSDART00000017268.8	ENSDARP00000008223.7

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.00e-23	81.8	647	677
UBD/Beta-Prp	9.10e-47	160.6	553	830

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 6    vtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           ++ +++ +d  +l++Gs+D+ +++++++++ 
   Q: 647  ISVVKYsPDgAYLAVGSHDNFVYIYSVTENG 677
           56678898989***************99765 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleet 132
           l   ++gh++e + ++ +p+++ +vt+++D+ +++wd  +  ++ t    ed ++s+ f+psg ++++G+      v d++t+  ++ +
   Q: 553  LTPIVQGHTDELWGLDVHPSTEQFVTCGQDKQVCLWDTCSHLPLWTKA-IEDPARSVGFHPSGTVVAVGTMTAKWLVLDTDTRDLVS-M 639
           55567899999999****999999***********9987776666655.99999999999999999999999999999999999999.9 PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.ktgkllrtl...tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec... 214
            +  ++++++v+++pdg +l+ Gs D++v ++++ ++gk   +    tg h + v++l+++ +++++v+ s d  + +w+ ++g+    
   Q: 640  HTDGNEIISVVKYSPDGAYLAVGSHDNFVYIYSVtENGKKYSRVgkcTG-HSSFVTHLDWSTDSQFIVTNSGDYEILYWEASSGKHitn 727
           9999999999999999999999999999999999855555555556588.999999999999999999999999999999997777677 PP
   S: 215  ...................................................................vrtlnghtdnvksvrfspnder 236
                                                                               +++ gh++ v+ v+f+ +d +
   Q: 728  ndivrnlewatstcvlgfsvfgiwpdgadgtdinavcrshdknllasaddfgkvhlfsnpcsqprapSHIYGGHSSHVTNVAFLHDDSH 816
           77777777777777888888888888888888888888888888888888888888888888888888888888888888888855544 PP
   S: 237  lvsgs.sDgsiriW 249
           l+s++ +D si  W
   Q: 817  LISTGgKDTSILQW 830
           44444488888877 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MSEKWEDGFE DRRFKIGRNN KGFAQKKDMS ERVASCGNLY DTNTLLLRYC NDDNVSAGSG 60
MEMDDRLSHL EQRVQLQEDE IQLLKAALAD ALRRLGCCEE ITQASNKKSG PTKVRQILQA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTGGGTAG CAGATGAGCG GTGAGGCTGT TGCTATAGAA ACGCAGGCAG TACAGGTTGT 60
CGTCGGCGGA AAGGTGTAGA AGGTTCACTC GTACTGTATG TCAGAAAAGT GGGAAGACGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0015630--C:microtubule cytoskeleton
GO:0008017--F:microtubule binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002155	Ailuropoda melanoleuca	66.25	0.00e+00	1025.00
IUUC-Aca-005316	Anolis carolinensis	69.67	0.00e+00	1057.00
IUUC-Ame-011647	Astyanax mexicanus	89.08	0.00e+00	1404.00
IUUC-Bta-013267	Bos taurus	65.53	0.00e+00	1040.00
IUUC-Cel-018623	Caenorhabditis elegans	31.09	7.00e-90	325.00
IUUC-Cfa-020267	Canis familiaris	65.85	0.00e+00	1045.00
IUUC-Dno-028961	Dasypus novemcinctus	65.31	0.00e+00	1002.00
IUUC-Eca-033785	Equus caballus	66.09	0.00e+00	1050.00
IUUC-Eeu-035302	Erinaceus europaeus	70.41	6.00e-159	554.00
IUUC-Gmo-039389	Gadus morhua	79.65	0.00e+00	1113.00
IUUC-Gac-042643	Gasterosteus aculeatus	80.52	0.00e+00	1252.00
IUUC-Itr-048788	Ictidomys tridecemlineatus	65.20	0.00e+00	1032.00
IUUC-Loc-052518	Lepisosteus oculatus	79.31	0.00e+00	1261.00
IUUC-Meu-056664	Macropus eugenii	69.95	0.00e+00	961.00
IUUC-Mmr-060853	Microcebus murinus	66.75	0.00e+00	1048.00
IUUC-Mmu-063860	Mus musculus	66.63	0.00e+00	1057.00
IUUC-Mpu-066043	Mustela putorius furo	66.54	0.00e+00	1047.00
IUUC-Ont-071258	Oreochromis niloticus	82.06	0.00e+00	1285.00
IUUC-Ola-086616	Oryzias latipes	76.74	0.00e+00	1149.00
IUUC-Pan-092082	Papio anubis	66.34	0.00e+00	1048.00
IUUC-Pma-094555	Petromyzon marinus	58.19	0.00e+00	825.00
IUUC-Pfo-096717	Poecilia formosa	80.00	0.00e+00	1309.00
IUUC-Pca-101070	Procavia capensis	61.66	0.00e+00	830.00
IUUC-Rno-105074	Rattus norvegicus	71.18	0.00e+00	979.00
IUUC-Tru-117809	Takifugu rubripes	77.22	0.00e+00	1276.00
IUUC-Tni-120815	Tetraodon nigroviridis	78.35	0.00e+00	1293.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence