iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049999

Ensembl Protein ID

ENSLACP00000011678.1

UniProt Accession

H3APV7; H3APV7_LATCH

Genbank Protein ID

ENSLACP00000011678

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01161997

Gene Name

USP24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000010278.1	ENSLACT00000011767.1	ENSLACP00000011678.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.60e-52	177.5	1682	2016

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgy 87
           +GlkN g+tCYmN+v Q+L++ p l e ll+     ++ee  ++p++++  ++q+lf +l++sk +++ p++++k++k++++e+   
   Q: 1682 VGLKNGGATCYMNAVFQQLYMQPGLSETLLS-----VDEE-TDNPDESVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVR 1762
           6******************************.....4433.367899**************************************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           eqqDa Ef++ l+dql+e+l                          kk   +++ +++Fqg +++q +c++c ++++ree+f+ l+l
   Q: 1763 EQQDAYEFFTSLVDQLDEYL--------------------------KKIGREQIFKNTFQGIFSDQKICKDCPHRYEREETFMALNL 1823
           ********************..........................678899*********************************** PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ld 260
            v + +     sl+ +L++f++ e l+g+n+yycekck+k++++k++ +k+lP vL++hL+Rf f+ e ++++k ++++ + +    
   Q: 1824 GVTSCQ-----SLEISLDQFVRGEVLDGSNAYYCEKCKEKRTTVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRVIEDyCF 1905
           ******.....9*******************************************************************98777444 PP
   S: 261  lsp.fcts....peekqke..........................kkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVte 316
            +p fc++    +     +                           ++Y+    +  +  +   HYv + k+  ++  l++ +    
   Q: 1906 TKPlFCHTslqnR-----SlvvksrnlfqekcngisvdkktvcvcICIYSCEHSIQMMD-FIIPHYVYLNKS-INEMALLNSQILAG 1985
           4444666633330.....24555555555566666665555555445554443333333.455788877777.55578888888888 PP
   S: 317  vkeeevleetg..........staYvlfYkr 337
            + +e+  + +          ++aY+lfY+r
   Q: 1986 NSNSEMFLFAAnpypdvrrryWNAYMLFYQR 2016
           8887777777778888888888888888887 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

METEEEQHMT TLLCMGFSDP MAIRKALRMA KNDINEAVAL LTNESPGLGY GYEPMESGPG 60
SGGDGGGGGG SSSSGSGGGG GSSSSGGRTG GGSGFDPPPA YHEVVEPTEK NDENGNCSGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGACCG AGGAAGAGCA GCACATGACG ACGCTGCTCT GCATGGGCTT CTCGGACCCG 60
ATGGCCATCC GCAAGGCCCT CCGCATGGCC AAAAACGACA TCAATGAGGC GGTGGCGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR033382--USP24
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50030--UBA
PS00972--USP_1
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0021551--P:central nervous system morphogenesis
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002266	Ailuropoda melanoleuca	80.34	0.00e+00	3852.00
IUUC-Apl-003203	Anas platyrhynchos	64.04	0.00e+00	2898.00
IUUC-Aca-004396	Anolis carolinensis	78.40	0.00e+00	3815.00
IUUC-Ame-011886	Astyanax mexicanus	78.01	0.00e+00	1587.00
IUUC-Bta-013381	Bos taurus	79.38	0.00e+00	3905.00
IUUC-Cel-018352	Caenorhabditis elegans	32.47	1.00e-44	176.00
IUUC-Cja-018955	Callithrix jacchus	79.74	0.00e+00	3486.00
IUUC-Cfa-020720	Canis familiaris	80.11	0.00e+00	3838.00
IUUC-Cpo-022430	Cavia porcellus	78.87	0.00e+00	2754.00
IUUC-Csa-024180	Chlorocebus sabaeus	80.18	0.00e+00	3687.00
IUUC-Cho-025074	Choloepus hoffmanni	71.68	0.00e+00	1352.00
IUUC-Dre-027696	Danio rerio	75.41	0.00e+00	3794.00
IUUC-Dno-029307	Dasypus novemcinctus	77.61	0.00e+00	3803.00
IUUC-Dor-030889	Dipodomys ordii	77.58	0.00e+00	3669.00
IUUC-Ete-032294	Echinops telfairi	78.17	0.00e+00	1935.00
IUUC-Eca-033823	Equus caballus	75.85	0.00e+00	3597.00
IUUC-Eeu-035178	Erinaceus europaeus	72.96	0.00e+00	1736.00
IUUC-Fca-035444	Felis catus	80.29	0.00e+00	3797.00
IUUC-Fal-037555	Ficedula albicollis	79.31	0.00e+00	3812.00
IUUC-Gmo-038587	Gadus morhua	75.57	0.00e+00	2318.00
IUUC-Gga-041231	Gallus gallus	79.30	0.00e+00	3918.00
IUUC-Gac-041584	Gasterosteus aculeatus	75.31	0.00e+00	2279.00
IUUC-Ggo-044502	Gorilla gorilla	79.46	0.00e+00	3883.00
IUUC-Hsa-045851	Homo sapiens	79.73	0.00e+00	3895.00
IUUC-Itr-048746	Ictidomys tridecemlineatus	73.56	0.00e+00	1111.00
IUUC-Loc-051767	Lepisosteus oculatus	78.15	0.00e+00	3825.00
IUUC-Laf-054139	Loxodonta africana	79.42	0.00e+00	3889.00
IUUC-Mcc-055217	Macaca mulatta	79.69	0.00e+00	3893.00
IUUC-Meu-056659	Macropus eugenii	69.45	0.00e+00	1822.00
IUUC-Mga-059267	Meleagris gallopavo	79.69	0.00e+00	3847.00
IUUC-Mmr-060971	Microcebus murinus	78.28	0.00e+00	3832.00
IUUC-Mdo-061925	Monodelphis domestica	79.54	0.00e+00	3834.00
IUUC-Mmu-064019	Mus musculus	79.61	0.00e+00	3945.00
IUUC-Mpu-066652	Mustela putorius furo	79.88	0.00e+00	3929.00
IUUC-Mlu-067518	Myotis lucifugus	80.20	0.00e+00	3808.00
IUUC-Nle-069763	Nomascus leucogenys	80.07	0.00e+00	3793.00
IUUC-Opr-071031	Ochotona princeps	77.28	0.00e+00	3176.00
IUUC-Ont-072136	Oreochromis niloticus	74.09	0.00e+00	3720.00
IUUC-Oan-072908	Ornithorhynchus anatinus	79.08	0.00e+00	906.00
IUUC-Ocu-073880	Oryctolagus cuniculus	78.88	0.00e+00	3887.00
IUUC-Ola-086544	Oryzias latipes	77.58	0.00e+00	2789.00
IUUC-Oga-088695	Otolemur garnettii	79.64	0.00e+00	3934.00
IUUC-Oar-089401	Ovis aries	79.99	0.00e+00	3797.00
IUUC-Ptr-091657	Pan troglodytes	80.19	0.00e+00	3809.00
IUUC-Pan-092394	Papio anubis	79.73	0.00e+00	3895.00
IUUC-Psi-093813	Pelodiscus sinensis	80.06	0.00e+00	3822.00
IUUC-Pma-094698	Petromyzon marinus	54.03	8.00e-137	480.00
IUUC-Pfo-096811	Poecilia formosa	74.23	0.00e+00	3684.00
IUUC-Pab-097814	Pongo abelii	79.65	0.00e+00	3894.00
IUUC-Pca-101135	Procavia capensis	74.17	0.00e+00	1686.00
IUUC-Pva-102334	Pteropus vampyrus	75.27	0.00e+00	3663.00
IUUC-Rno-105040	Rattus norvegicus	79.16	0.00e+00	3930.00
IUUC-Sha-106658	Sarcophilus harrisii	79.83	0.00e+00	3841.00
IUUC-Sar-113153	Sorex araneus	73.42	0.00e+00	2335.00
IUUC-Ssc-115641	Sus scrofa	79.36	0.00e+00	3651.00
IUUC-Tgu-117467	Taeniopygia guttata	80.38	0.00e+00	2825.00
IUUC-Tru-118074	Takifugu rubripes	67.27	0.00e+00	3139.00
IUUC-Tsy-119165	Tarsius syrichta	79.80	0.00e+00	1845.00
IUUC-Tni-119923	Tetraodon nigroviridis	64.12	0.00e+00	2957.00
IUUC-Tbe-127910	Tupaia belangeri	73.78	0.00e+00	1199.00
IUUC-Ttr-128218	Tursiops truncatus	78.80	0.00e+00	3782.00
IUUC-Vpa-130090	Vicugna pacos	81.33	0.00e+00	1417.00
IUUC-Xtr-131911	Xenopus tropicalis	83.08	0.00e+00	1503.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence