iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-028132

Ensembl Protein ID

ENSDARP00000117685.1

UniProt Accession

B0R199; B0R199_DANRE

Genbank Protein ID

ENSDARP00000117685

Protein Name

Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta

Genbank Nucleotide ID

AL954172

Gene Name

ikbkb

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000079123.4	ENSDART00000140265.1	ENSDARP00000117685.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UBQ/UBQ_Other	1.10e-06	29.4	341	401

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_Other

   S: 3    vtvksldgs.eltlkvnpsdtVaeLKekiekklgippeqqrLiyk.GkiLeddktLadygl 61
           v+v +++++ ++ ++v p d Va L+e+i + +gipp+ q L+++ G  Le+ +++ ++ +
   Q: 341  VHVLNMTSAeIFNYSVQPEDDVASLQERIAQDTGIPPANQELLLEaGLALEPQNSVMQCAI 401
           8999***************************************999*********999866 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MSRPPSMQPQ TCGPWELKER LGTGGFGNVT LWQNKETSIQ IAIKQCRQEL SVKNKGRWSL 60
EIQIMKRLTH MNVVAARDVP EELQKLATND LPLLAMEFCQ GGDLRKYLNL VENCCGMREA 120

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Nucleotide Sequence
(Fasta)

TTTCAGGAAG TAGAGAAACT CAACGCTCTT CTGCTTTCAA ACACAATCAC AAACCTCTTT 60
ACAGTCTGAT TTACCGAACA AATCCGTTAA ATGTGTAAAA GTCGCGGGAA TAATCAGCTG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50053--UBIQUITIN_2

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0008385--C:IkappaB kinase complex
GO:0005524--F:ATP binding
GO:0004672--F:protein kinase activity
GO:0009653--P:anatomical structure morphogenesis
GO:0007252--P:I-kappaB phosphorylation
GO:0006954--P:inflammatory response
GO:0045087--P:innate immune response
GO:0018105--P:peptidyl-serine phosphorylation
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

KEGG

dre:563560

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-010999	Astyanax mexicanus	76.90	0.00e+00	1016.00
IUUC-Ola-086737	Oryzias latipes	70.62	0.00e+00	1047.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence