iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT3G04380	AT3G04380.2	AT3G04380.2
AT3G04380	AT3G04380.4	AT3G04380.4
AT3G04380	AT3G04380.1	AT3G04380.1
AT3G04380	AT3G04380.6	AT3G04380.6

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
HINT	Mentha
Protein 3D Structure
PDB
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
UBD/Alpha-Helix/WIYLD	WIYLD	24625295

Organism

Arabidopsis thaliana

Functional Description
(View)

Histone methyltransferase that converts monomethylated 'Lys-9' of histone H3 (H3K9me1) to dimethylated 'Lys-9' (H3K9me2) in the absence of bound ubiquitin, and to trimethylated 'Lys-9' (H3K9me3) in the presence of bound ubiquitin. Acts in a locus-specific manner and contributes to the transcriptional silencing of pseudogenes and transposons. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression.

Protein Sequence
(Fasta)

MISLSGLTSS VESDLDMQQA MLTNKDEKVL KALERTRQLD IPDEKTMPVL MKLLEEAGGN 60
WSYIKLDNYT ALVDAIYSVE DENKQSEGSS NGNRGKNLKV IDSPATLKKT YETRSASSGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAACAATTGT ATGTATACTC ACGCACGACG CAGTGAAACA GAGATACTGT GGAAAAGTGT 60
GTTTAAAATG GATCTGTTTT AGGGTATTTA TCAATTCGAA AATTGATTAA TTTATTAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc

Interpro

IPR007728--Pre-SET_dom
IPR001214--SET_dom
IPR025776--SUVR4/1/2
IPR018848--WIYLD_domain

PROSITE

PS50867--PRE_SET
PS51580--SAM_MT43_3
PS50280--SET

Pfam

PF05033--Pre-SET
PF00856--SET
PF10440--WIYLD

SMART

SM00468--PreSET
SM00317--SET

Gene Ontology

GO:0005694--C:chromosome
GO:0005730--C:nucleolus
GO:0009506--C:plasmodesma
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0034968--P:histone lysine methylation

KEGG

ath:AT3G04380

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000310	Aegilops tauschii	53.83	2.00e-122	432.00
IUUC-Aly-005582	Arabidopsis lyrata	93.28	0.00e+00	931.00
IUUC-Bol-016259	Brassica oleracea	74.75	0.00e+00	738.00
IUUC-Bra-017530	Brassica rapa	75.15	0.00e+00	739.00
IUUC-Dre-027664	Danio rerio	33.17	8.00e-17	82.80
IUUC-Gmo-038901	Gadus morhua	29.80	3.00e-13	70.90
IUUC-Gma-043669	Glycine max	68.77	5.00e-134	471.00
IUUC-Lpe-051661	Leersia perrieri	55.83	4.00e-125	442.00
IUUC-Mtr-057972	Medicago truncatula	66.77	4.00e-133	467.00
IUUC-Mdo-061984	Monodelphis domestica	31.12	3.00e-14	74.70
IUUC-Obr-076178	Oryza brachyantha	51.72	3.00e-127	448.00
IUUC-Olo-080770	Oryza longistaminata	52.20	2.00e-126	445.00
IUUC-Opu-083717	Oryza punctata	61.20	2.00e-116	412.00
IUUC-Oru-084221	Oryza rufipogon	52.20	2.00e-126	445.00
IUUC-Ola-087085	Oryzias latipes	32.99	2.00e-14	74.70
IUUC-Ppa-095277	Physcomitrella patens	57.19	8.00e-103	367.00
IUUC-Pfo-096669	Poecilia formosa	32.49	6.00e-14	73.20
IUUC-Ppe-101882	Prunus persica	49.52	2.00e-142	498.00
IUUC-Smo-109061	Selaginella moellendorffii	51.96	2.00e-99	355.00
IUUC-Sit-110333	Setaria italica	59.88	9.00e-126	443.00
IUUC-Sly-110907	Solanum lycopersicum	57.70	7.00e-128	450.00
IUUC-Stu-112290	Solanum tuberosum	57.18	2.00e-127	449.00
IUUC-Sbi-114254	Sorghum bicolor	55.40	2.00e-124	439.00
IUUC-Tvi-122329	Trichoderma virens	26.23	2.90e+00	25.80
IUUC-Tae-124687	Triticum aestivum	53.83	3.00e-123	435.00
IUUC-Vvi-131608	Vitis vinifera	59.53	2.00e-129	455.00
IUUC-Xma-134036	Xiphophorus maculatus	32.49	9.00e-14	72.80

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence