iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tca-120918

Ensembl Protein ID

EOX97899

UniProt Accession

A0A061DYN7; A0A061DYN7_THECC

Genbank Protein ID

EOX97899.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

CM001880

Gene Name

TCM_006812

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TCM_006812	EOX97899	EOX97899

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.50e-38	128.3	91	127
UBD/Beta-Prp	2.20e-76	257.9	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH d ++ ++f ++ + +vs+sdD ti++W++ + ++
   Q: 91   GHLDYIRTVQFhHEhPWIVSASDDQTIRIWNWQSRTC 127
           8**********97779***************987766 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           t +++++++++ + f+ ++++++++  +g i++wd+++g+l+ ++ +h+++v+ v f+ +++++v+g++D+ ikvw+++   c+ tl gh d++++++f+ 
   Q: 3    TKFETKSNRVKGLSFHAKRPWILASLHSGVIQLWDYRMGTLIDRFDEHDGPVRGVHFHMSQPLFVSGGDDYKIKVWNYKLHRCLFTLLGHLDYIRTVQFHH 103
           67889999********************************************************************************************* PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..........................ktgkllrtltggh 179
           +  ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+++hp+++l+vs+slD+tvr+Wd+                            +++++   +gh
   Q: 104  EHPWIVSASDDQTIRIWNWQSRTCIS-VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIgslrkktvspaddilrlsqmntdlfgGVDSVVKYVLEGH 203
           **************************.**************************************************88877777777555555555666* PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdn 278
           ++ v++ +f+++ + +vsg++d++vklw + +++   v+tl+gh +nv++v f+ +++++vs s+D+sir+Wd+++++ l+t+ +++++++  a+ +++ n
   Q: 204  DRGVNWAAFHPTLPLIVSGADDRQVKLWRMNETKAweVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKSIRVWDVTKRTGLQTFRREHDRFWILAA-HPEMN 303
           *******************************887778**********************************************************.66666 PP
   S: 279  vlvlgsedskvniwklkknep 299
            l++g  ds   ++kl++++p
   Q: 304  LLAAG-HDSGMIVFKLERERP 323
           55555.689999999988765 PP

Organism

Theobroma cacao

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHAK RPWILASLHS GVIQLWDYRM GTLIDRFDEH DGPVRGVHFH 60
MSQPLFVSGG DDYKIKVWNY KLHRCLFTLL GHLDYIRTVQ FHHEHPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATCAATAGC TTTGTTACGG CAACAGCCAT TAATCTTTAA AACAGAGAGA ATCGATGCCT 60
CTCTCTTTTC TTTTCATATA AAGCTAAAGA TACAAAGGTG CTATCGTTTT CGTTTGTAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003385	Anas platyrhynchos	49.86	0.00e+00	1044.00
IUUC-Aly-006020	Arabidopsis lyrata	83.87	0.00e+00	2080.00
IUUC-Ath-007360	Arabidopsis thaliana	83.84	0.00e+00	2079.00
IUUC-Bol-015925	Brassica oleracea	82.57	0.00e+00	2050.00
IUUC-Bra-016978	Brassica rapa	83.46	0.00e+00	2063.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	72.24	0.00e+00	1280.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	56.42	0.00e+00	978.00
IUUC-Cme-027222	Cyanidioschyzon merolae	43.16	2.00e-149	523.00
IUUC-Dse-031543	Dothistroma septosporum	47.50	0.00e+00	1077.00
IUUC-Eeu-034874	Erinaceus europaeus	41.82	0.00e+00	658.00
IUUC-Fal-037263	Ficedula albicollis	51.62	0.00e+00	1216.00
IUUC-Fso-038153	Fusarium solani	47.93	0.00e+00	1120.00
IUUC-Kpa-049256	Komagataella pastoris	44.87	0.00e+00	1035.00
IUUC-Laf-053510	Loxodonta africana	55.64	0.00e+00	1392.00
IUUC-Mpo-057300	Magnaporthe poae	47.69	0.00e+00	1101.00
IUUC-Ncr-068892	Neurospora crassa	56.66	0.00e+00	982.00
IUUC-Opr-070952	Ochotona princeps	42.37	0.00e+00	661.00
IUUC-Olo-080466	Oryza longistaminata	84.46	0.00e+00	1511.00
IUUC-Ome-081993	Oryza meridionalis	84.34	0.00e+00	1393.00
IUUC-Ola-086921	Oryzias latipes	54.18	0.00e+00	1330.00
IUUC-Ppa-095785	Physcomitrella patens	71.35	0.00e+00	1815.00
IUUC-Ppe-101899	Prunus persica	88.93	0.00e+00	2185.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	57.61	0.00e+00	966.00
IUUC-Tsy-119105	Tarsius syrichta	53.05	0.00e+00	1050.00
IUUC-Tvi-122359	Trichoderma virens	57.14	0.00e+00	993.00
IUUC-Uma-129337	Ustilago maydis	55.60	0.00e+00	996.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence