iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dse-031472

Ensembl Protein ID

EME47496

UniProt Accession

N1PVJ6; N1PVJ6_DOTSN

Genbank Protein ID

EME47496.1

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

KB446536

Gene Name

DOTSEDRAFT_69438

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
DOTSEDRAFT_69438	EME47496	EME47496

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	6.00e-184	612.5	43	676

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 12   qesv.kkeyeelytavynlclsk..................vgaklYkklkevleefikqvkkkveesedeqlLktynreWekfreqlkvlrkifayldrt 93
           ++ v  k+y+ lyt+++n+c+++                  +g+ lY++l+ +l+ +++qv++++ +++de+lL +y++eW++++++  + +++f+yl+r+
   Q: 43   KDGVdLKTYMSLYTSIHNFCTAQkavgtgqalnstsrgahlLGEDLYHRLNGYLKGHLAQVHSDMIQHQDEALLTFYIKEWKRYTQAGMYNNHLFRYLNRH 143
           57787899**************9****************************************************************************** PP
   S: 94   yvkk.....skkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvveslveLslnk.......laiykesFEakfleatqefyka 182
           +vk+     +k+++++++L l  w+++++   ++ +++++l+l+e++R+ge+++++ +++vv+s+v+L++++       l +y++ FE+++l+at+ +y +
   Q: 144  WVKRemdegKKDIYDIYTLHLVRWKEDMFGTTQNAVMDAVLRLVEKQRNGETIEQSKVKEVVNSFVSLGIDEadstkttLDVYRQYFEKPYLDATATYYDK 244
           ****999999999**************************************************************************************** PP
   S: 183  esaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesllaelvallrdkktedlsrmykLlsrvlngleellkeleshikeq 283
           es++fl+en+v +Y+kk+e+rl ee er+  yl +    +L++++e+ liakh+  l +e++ ll++++++d++rmykLl+r+++gl++l+ ++e+h++ +
   Q: 245  ESQSFLAENSVVDYMKKAEKRLDEERERVPLYLLPEIMVPLMKTCESSLIAKHAPVLRDEFQILLDNDREDDMARMYKLLARIPEGLDPLRAKFETHVRAA 345
           ***************************************************************************************************** PP
   S: 284  gkaalt...aeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlka..akspEllAryiDqlLrksskglteeeleaqldkv 379
           g++a++   ++ ++ dpk y+  lle++ ++  lv++aF  + +F+ +ld+a+++ vn+n+       +spEllA++ D+ L++s k ++e ++e++ld++
   Q: 346  GHQAVEkvaDQGENLDPKAYIDALLEVHTQYAALVQTAFTGESEFVRSLDNACREYVNRNKACAKnsNRSPELLAKHSDNVLKRSTKATEEDDMEKMLDHI 446
           *****9886777777*******************************************9966544668999****************************** PP
   S: 380  llvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfqdlkvSedlnrqFk....eekenteesesvelsvlvLsagaW 476
           +++fkyi++kdvF+k+Y +hLakRL++g+sas +aE s+i+kLk + g+e+t+kL+rM+qd+++S+dln++++    ++ +++  + +v+ + +vL +g+W
   Q: 447  MTIFKYIEDKDVFQKFYSRHLAKRLVNGTSASPDAETSMISKLKDASGFEYTNKLQRMYQDIQTSKDLNAEYEdwrsQNIDKEDRKDEVDANYQVLGTGFW 547
           ************************************************************************98876666666677889999********* PP
   S: 477  ptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelkkg...kyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqs 574
           p ++    ++ P  + kt+e+f +fY++kh gRkL+W+++l+++e++a++ k    +y++qVst+Qma+LL+fn+s++vs++e +++t l +e L   ++ 
   Q: 548  PLQPPSTPFTPPLAIVKTYERFATFYNKKHGGRKLSWLWHLCKGEIRANYVKMnkvPYTFQVSTYQMAILLMFNDSDTVSYDEFSEITSLAKETLDPSIGI 648
           ***55555****************************************98544556********************************************* PP
   S: 575  LvsskkqvlkkepeskeieeedlfsvNqef 604
           +++ k  vl+++pe+++ ++++ +s+Nq f
   Q: 649  MIKAK--VLTASPEGASPQSGTAYSLNQGF 676
           ***98..********************987 PP

Organism

Dothistroma septosporum

Protein Sequence
(Fasta)

MSTQAAAAAA SRPPPPLPQS KDDIVGTWNF LEWGVEKIMY SLKDGVDLKT YMSLYTSIHN 60
FCTAQKAVGT GQALNSTSRG AHLLGEDLYH RLNGYLKGHL AQVHSDMIQH QDEALLTFYI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCACGCTA TTCTCTCCCT CCTTCCTTCT ACCACCACCT CTGCCGCTAC AGATAGCAGA 60
TAAAACCAAA AAGCATATTA TTCAGCAGCA CGACAATTCA CTGCTAGTAA TAACACGCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0005829--C:cytosol
GO:0043224--C:nuclear SCF ubiquitin ligase complex
GO:1903467--P:negative regulation of mitotic DNA replication initiation
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000358	Aegilops tauschii	29.21	1.00e-88	318.00
IUUC-Aml-002277	Ailuropoda melanoleuca	45.84	0.00e+00	646.00
IUUC-Apl-003503	Anas platyrhynchos	44.11	3.00e-143	500.00
IUUC-Aca-005030	Anolis carolinensis	40.28	7.00e-134	469.00
IUUC-Ago-007977	Ashbya gossypii	35.83	1.00e-140	492.00
IUUC-Acl-008190	Aspergillus clavatus	66.49	0.00e+00	1035.00
IUUC-Afl-008542	Aspergillus flavus	65.53	0.00e+00	812.00
IUUC-Afu-009007	Aspergillus fumigatus	64.08	0.00e+00	976.00
IUUC-Ani-009290	Aspergillus nidulans	64.29	0.00e+00	1034.00
IUUC-Ang-009600	Aspergillus niger	63.87	0.00e+00	979.00
IUUC-Aor-009978	Aspergillus oryzae	62.62	0.00e+00	897.00
IUUC-Ate-010584	Aspergillus terreus	66.75	0.00e+00	1040.00
IUUC-Ame-011861	Astyanax mexicanus	45.90	0.00e+00	638.00
IUUC-Bgr-012209	Blumeria graminis	61.93	0.00e+00	952.00
IUUC-Bta-012878	Bos taurus	45.84	0.00e+00	643.00
IUUC-Bci-013941	Botrytis cinerea	64.03	0.00e+00	1034.00
IUUC-Cel-018294	Caenorhabditis elegans	37.84	2.00e-155	541.00
IUUC-Cja-018965	Callithrix jacchus	44.36	5.00e-178	616.00
IUUC-Cfa-020671	Canis familiaris	45.84	0.00e+00	643.00
IUUC-Cpo-021762	Cavia porcellus	45.84	0.00e+00	643.00
IUUC-Cre-022585	Chlamydomonas reinhardtii	30.99	4.00e-95	340.00
IUUC-Csa-023873	Chlorocebus sabaeus	45.71	0.00e+00	643.00
IUUC-Cin-025547	Ciona intestinalis	44.88	4.00e-176	609.00
IUUC-Csv-026083	Ciona savignyi	45.68	0.00e+00	644.00
IUUC-Cgl-026452	Colletotrichum gloeosporioides	62.42	0.00e+00	983.00
IUUC-Cne-026919	Cryptococcus neoformans	45.92	0.00e+00	663.00
IUUC-Dre-027875	Danio rerio	45.78	0.00e+00	637.00
IUUC-Dno-028931	Dasypus novemcinctus	45.84	0.00e+00	639.00
IUUC-Dor-030846	Dipodomys ordii	48.57	7.00e-133	466.00
IUUC-Dme-031793	Drosophila melanogaster	43.10	8.00e-175	605.00
IUUC-Ete-033112	Echinops telfairi	43.22	1.00e-70	259.00
IUUC-Eca-034309	Equus caballus	45.84	0.00e+00	643.00
IUUC-Fca-036330	Felis catus	44.56	6.00e-180	622.00
IUUC-Fal-036899	Ficedula albicollis	43.81	2.00e-148	517.00
IUUC-Fox-037705	Fusarium oxysporum	57.26	0.00e+00	894.00
IUUC-Fso-038367	Fusarium solani	59.76	0.00e+00	940.00
IUUC-Gmo-038708	Gadus morhua	45.01	0.00e+00	633.00
IUUC-Ggr-039917	Gaeumannomyces graminis	63.10	0.00e+00	975.00
IUUC-Gga-041038	Gallus gallus	45.84	0.00e+00	643.00
IUUC-Gac-041820	Gasterosteus aculeatus	45.67	0.00e+00	661.00
IUUC-Ggo-045154	Gorilla gorilla	40.33	4.00e-128	450.00
IUUC-Hsa-046034	Homo sapiens	45.71	0.00e+00	643.00
IUUC-Itr-048285	Ictidomys tridecemlineatus	45.84	0.00e+00	643.00
IUUC-Kpa-049231	Komagataella pastoris	38.16	1.00e-153	535.00
IUUC-Lch-049673	Latimeria chalumnae	45.45	0.00e+00	642.00
IUUC-Loc-052490	Lepisosteus oculatus	46.16	0.00e+00	637.00
IUUC-Lma-053191	Leptosphaeria maculans	73.94	0.00e+00	1122.00
IUUC-Laf-054582	Loxodonta africana	45.84	0.00e+00	643.00
IUUC-Mcc-055162	Macaca mulatta	45.45	0.00e+00	631.00
IUUC-Meu-055904	Macropus eugenii	44.60	2.00e-70	258.00
IUUC-Mor-057035	Magnaporthe oryzae	62.24	0.00e+00	946.00
IUUC-Mpo-057555	Magnaporthe poae	63.10	0.00e+00	974.00
IUUC-Mla-059021	Melampsora laricipopulina	47.53	0.00e+00	691.00
IUUC-Mga-060078	Meleagris gallopavo	45.84	0.00e+00	643.00
IUUC-Mvi-060519	Microbotryum violaceum	50.07	0.00e+00	738.00
IUUC-Mmr-061312	Microcebus murinus	45.71	0.00e+00	643.00
IUUC-Mdo-062867	Monodelphis domestica	45.71	0.00e+00	638.00
IUUC-Mmu-063336	Mus musculus	45.84	0.00e+00	643.00
IUUC-Mpu-066400	Mustela putorius furo	43.81	3.00e-148	517.00
IUUC-Mlu-067800	Myotis lucifugus	45.45	0.00e+00	645.00
IUUC-Nfi-068384	Neosartorya fischeri	63.97	0.00e+00	979.00
IUUC-Ncr-068965	Neurospora crassa	60.10	0.00e+00	930.00
IUUC-Nle-069729	Nomascus leucogenys	45.71	0.00e+00	643.00
IUUC-Opr-071197	Ochotona princeps	33.04	1.00e-103	369.00
IUUC-Ont-071729	Oreochromis niloticus	46.10	0.00e+00	654.00
IUUC-Oan-073309	Ornithorhynchus anatinus	45.84	0.00e+00	643.00
IUUC-Ocu-074661	Oryctolagus cuniculus	45.19	0.00e+00	633.00
IUUC-Ola-087422	Oryzias latipes	46.24	0.00e+00	658.00
IUUC-Olu-087721	Ostreococcus lucimarinus	27.91	2.00e-79	288.00
IUUC-Oga-088130	Otolemur garnettii	45.71	0.00e+00	643.00
IUUC-Oar-089510	Ovis aries	44.15	7.00e-172	595.00
IUUC-Ptr-090665	Pan troglodytes	45.71	0.00e+00	643.00
IUUC-Pan-092218	Papio anubis	45.71	0.00e+00	643.00
IUUC-Psi-093175	Pelodiscus sinensis	45.84	0.00e+00	644.00
IUUC-Pma-094502	Petromyzon marinus	46.04	0.00e+00	643.00
IUUC-Pno-095067	Phaeosphaeria nodorum	72.89	0.00e+00	1145.00
IUUC-Pfo-096705	Poecilia formosa	46.22	0.00e+00	666.00
IUUC-Pab-097578	Pongo abelii	45.71	0.00e+00	643.00
IUUC-Pca-100242	Procavia capensis	47.32	1.00e-130	458.00
IUUC-Pva-102155	Pteropus vampyrus	39.92	2.00e-149	521.00
IUUC-Pgr-103297	Puccinia graminis	47.97	0.00e+00	717.00
IUUC-Ptt-103706	Puccinia triticina	46.77	3.00e-107	382.00
IUUC-Pte-104257	Pyrenophora teres	72.89	0.00e+00	1145.00
IUUC-Pyt-104795	Pyrenophora triticirepentis	73.03	0.00e+00	1144.00
IUUC-Rno-105939	Rattus norvegicus	45.84	0.00e+00	643.00
IUUC-Sce-106293	Saccharomyces cerevisiae	32.11	9.00e-128	449.00
IUUC-Sha-106949	Sarcophilus harrisii	45.84	0.00e+00	643.00
IUUC-Sja-107737	Schizosaccharomyces japonicus	45.99	0.00e+00	643.00
IUUC-Spo-108280	Schizosaccharomyces pombe	46.77	0.00e+00	667.00
IUUC-Sar-113138	Sorex araneus	36.27	1.00e-128	451.00
IUUC-Sre-114984	Sporisorium reilianum	47.62	0.00e+00	691.00
IUUC-Ssc-115829	Sus scrofa	45.77	0.00e+00	635.00
IUUC-Tgu-116950	Taeniopygia guttata	45.84	0.00e+00	643.00
IUUC-Tru-118558	Takifugu rubripes	45.45	0.00e+00	655.00
IUUC-Tsy-119621	Tarsius syrichta	37.79	6.00e-102	363.00
IUUC-Tni-120460	Tetraodon nigroviridis	45.58	0.00e+00	662.00
IUUC-Tre-122223	Trichoderma reesei	59.71	0.00e+00	897.00
IUUC-Tvi-122539	Trichoderma virens	58.31	0.00e+00	877.00
IUUC-Tme-126926	Tuber melanosporum	65.84	0.00e+00	1031.00
IUUC-Tbe-127831	Tupaia belangeri	30.67	2.00e-93	335.00
IUUC-Ttr-129022	Tursiops truncatus	45.12	2.00e-143	501.00
IUUC-Uma-129341	Ustilago maydis	48.55	0.00e+00	670.00
IUUC-Vda-129857	Verticillium dahliae	61.47	0.00e+00	932.00
IUUC-Vpa-130166	Vicugna pacos	40.77	4.00e-132	463.00
IUUC-Xtr-131818	Xenopus tropicalis	45.45	0.00e+00	640.00
IUUC-Xma-134206	Xiphophorus maculatus	45.96	0.00e+00	646.00
IUUC-Yli-134486	Yarrowia lipolytica	41.59	1.00e-168	584.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence