iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sly-111178

Ensembl Protein ID

Solyc02g088780.2.1

UniProt Accession

K4BC33; K4BC33_SOLLC

Protein Name

Ribosome biogenesis protein WDR12 homolog

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Solyc02g088780.2	Solyc02g088780.2.1	Solyc02g088780.2.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-28	98.1	365	399
UBD/Beta-Prp	1.30e-40	140.2	271	417

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtg 33
           H+++++++++   +  +lvs+s+Dg++++WDlrt 
   Q: 365  HSSWISACKWheKSrFHLVSASYDGKVMLWDLRTA 399
           **********9944478***************986 PP

UBD/Beta-Prp

   S: 85   kcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl...ktgkl 171
           +  +tl gh++ v s+ + + ++++ s+s+d  ir wd+e g+ +   +   d+vvnc+ v ++g +l+++G+ D ++r+Wd     +   
   Q: 271  EAKSTLVGHTQCVSSVVWPQ-DETIYSASWDHSIRRWDVEMGKDSL--NLYCDKVVNCLDVGGEGsSLIAAGGSDPVLRIWDPrkpGSSAP 358
           5678999*********9988.99**********************5..89999******************************87778899 PP
   S: 172  lrtltgghtdsvyslsfdsng.kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrf 230
           ++++++ h + +   ++++++ ++lvs+s+dg+v lwdl+t   +     h+d v++vr 
   Q: 359  VYQFSS-HSSWISACKWHEKSrFHLVSASYDGKVMLWDLRTAWPLAVIDTHKDKVYCVRI 417
           9***99.*********9988879***********************************85 PP

Organism

Solanum lycopersicum

Functional Description
(View)

Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.

Protein Sequence
(Fasta)

MAGMDIDGNV EEAARRVQVR FVTKLKAPFK APPTSIAIPS NLTRLGLSSI VNNLLKAGND 60
DWNPEPFDFL IDGELVRMSL EEFLLAKGIS AEKILEIEYI RAVAPRKEEE PSLHDDWVSA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCGTGAAC GTCTCTACCC TCACACTCCG CACCCTTCTC TCTCTCTACA CAATACTTTT 60
TTAATGGCGG GTATGGACAT TGATGGCAAC GTTGAAGAGG CTGCAAGGCG TGTACAGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR012972--NLE
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR028599--WDR12/Ytm1

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08154--NLE
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0000460--P:maturation of 5.8S rRNA
GO:0000466--P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000470--P:maturation of LSU-rRNA
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004370	Anolis carolinensis	32.76	1.00e-60	226.00
IUUC-Acl-008177	Aspergillus clavatus	30.68	5.00e-41	161.00
IUUC-Afl-008617	Aspergillus flavus	29.77	4.00e-40	158.00
IUUC-Afu-008752	Aspergillus fumigatus	29.74	3.00e-40	158.00
IUUC-Ani-009136	Aspergillus nidulans	31.30	1.00e-43	169.00
IUUC-Ang-009701	Aspergillus niger	29.98	3.00e-38	152.00
IUUC-Aor-009884	Aspergillus oryzae	30.00	2.00e-41	162.00
IUUC-Ame-011432	Astyanax mexicanus	34.00	1.00e-64	239.00
IUUC-Bgr-012218	Blumeria graminis	29.90	5.00e-40	157.00
IUUC-Bci-013953	Botrytis cinerea	29.98	3.00e-44	171.00
IUUC-Cfa-020471	Canis familiaris	32.84	4.00e-52	198.00
IUUC-Cre-022614	Chlamydomonas reinhardtii	38.19	8.00e-68	249.00
IUUC-Cho-024426	Choloepus hoffmanni	31.72	3.00e-41	161.00
IUUC-Cne-027063	Cryptococcus neoformans	28.44	5.00e-32	131.00
IUUC-Dre-027907	Danio rerio	33.50	1.00e-63	236.00
IUUC-Dno-029225	Dasypus novemcinctus	32.84	1.00e-53	202.00
IUUC-Dor-031082	Dipodomys ordii	25.65	3.00e-33	135.00
IUUC-Dse-031308	Dothistroma septosporum	30.19	5.00e-43	167.00
IUUC-Eeu-035322	Erinaceus europaeus	30.77	3.00e-46	178.00
IUUC-Fox-037965	Fusarium oxysporum	26.98	3.00e-33	135.00
IUUC-Fso-038244	Fusarium solani	27.15	7.00e-33	134.00
IUUC-Gmo-039040	Gadus morhua	34.83	8.00e-66	243.00
IUUC-Ggr-040093	Gaeumannomyces graminis	25.68	1.00e-27	117.00
IUUC-Gac-042117	Gasterosteus aculeatus	36.07	1.00e-64	239.00
IUUC-Itr-048275	Ictidomys tridecemlineatus	33.08	6.00e-54	204.00
IUUC-Lch-050655	Latimeria chalumnae	34.39	1.00e-48	186.00
IUUC-Meu-056501	Macropus eugenii	34.94	7.00e-50	190.00
IUUC-Mor-057114	Magnaporthe oryzae	27.32	2.00e-37	149.00
IUUC-Mla-059107	Melampsora laricipopulina	26.67	1.00e-36	146.00
IUUC-Mvi-060362	Microbotryum violaceum	25.12	5.00e-30	125.00
IUUC-Mdo-062257	Monodelphis domestica	33.83	3.00e-58	218.00
IUUC-Mlu-067241	Myotis lucifugus	33.08	1.00e-53	203.00
IUUC-Nfi-068260	Neosartorya fischeri	31.55	2.00e-42	166.00
IUUC-Ncr-068719	Neurospora crassa	26.84	1.00e-34	140.00
IUUC-Nle-068981	Nomascus leucogenys	33.33	5.00e-52	197.00
IUUC-Opr-071218	Ochotona princeps	32.59	1.00e-53	202.00
IUUC-Ont-071646	Oreochromis niloticus	33.83	1.00e-59	222.00
IUUC-Oan-073453	Ornithorhynchus anatinus	33.83	1.00e-64	239.00
IUUC-Oba-075712	Oryza barthii	52.96	1.00e-118	419.00
IUUC-Ogu-078977	Oryza glumaepatula	52.96	5.00e-119	420.00
IUUC-Olo-080291	Oryza longistaminata	53.11	2.00e-89	321.00
IUUC-Ola-087420	Oryzias latipes	34.83	3.00e-66	244.00
IUUC-Oga-088264	Otolemur garnettii	32.84	7.00e-53	200.00
IUUC-Pfo-096337	Poecilia formosa	33.83	7.00e-65	240.00
IUUC-Pva-102921	Pteropus vampyrus	31.56	1.00e-24	106.00
IUUC-Pgr-103637	Puccinia graminis	26.12	6.00e-35	140.00
IUUC-Ptt-103781	Puccinia triticina	25.76	6.00e-35	140.00
IUUC-Sha-107122	Sarcophilus harrisii	34.24	6.00e-56	210.00
IUUC-Ssl-108398	Sclerotinia sclerotiorum	30.17	3.00e-45	175.00
IUUC-Smo-108720	Selaginella moellendorffii	49.39	1.00e-111	395.00
IUUC-Stu-112778	Solanum tuberosum	96.86	0.00e+00	790.00
IUUC-Tsy-119573	Tarsius syrichta	25.41	1.00e-19	90.10
IUUC-Tni-119820	Tetraodon nigroviridis	35.98	3.00e-62	231.00
IUUC-Tre-121947	Trichoderma reesei	27.55	1.00e-37	150.00
IUUC-Tvi-122481	Trichoderma virens	27.48	1.00e-36	146.00
IUUC-Tbe-127736	Tupaia belangeri	28.70	5.00e-31	127.00
IUUC-Ttr-129041	Tursiops truncatus	28.86	1.00e-38	152.00
IUUC-Uma-129628	Ustilago maydis	29.20	1.00e-10	60.80
IUUC-Xtr-132083	Xenopus tropicalis	35.24	3.00e-59	221.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence