iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020347

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03003657

Gene Name

USP43

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000017439.4	ENSCAFT00000027639.4	ENSCAFP00000025704.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.20e-91	305.6	91	700

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN+gNtC+mN+v+QcLsn+  l+e+l     ++ +        +e++++l+ l+++lw+++ +     e+++a++k+ ++f+g++q
   Q: 91   QGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYRAAPG------RAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNAQ 173
           6****************************9955555555......479***************************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +Da Efl +lld+++e+l+ +++ p  e+ + + ++++++  ++  + + ++s+++  Fq q++s+++c++c ++s++++pfl +slp+
   Q: 174  HDALEFLLWLLDRVHEDLEGSSRGPGAEKLQPEANKTPENlpSPPAQLSLGQSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPI 262
           ******************9988888888888888888888667778888899************************************* PP
   S: 177  pgkeetkke................................................................................ 185
           p ++++ ++                                                                                
   Q: 263  PLRQTRFLSvtlvfpsksqrflrvglavpilstvaalrkmvseegdipadevilvelcpngfqrsffdeedlntisegdnvyafhappp 351
           ****98888******************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 352  pgqetlsahpcglsvsprlaaregqrvplsvpsknkvlilicnlvgsgqqasrfgppfllredraitwvqlqqrilsnvrcvmksevpi 440
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 441  qnpgslfsvrvvglslacsylsphdshplchwavdramhlrrpggpphiklavewescakerlfgnlqeervqdadsvwrqqqahqqhs 529
           ***************************************************************************************** PP
   S: 186  .slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfctspeekq 272
            +l++c++ +tkee+l ++++++c++c+++q+   kl+l++lP++Li+hLkRf   + +++r+k+++ v fpl+ Ld++p+++++  + 
   Q: 530  cTLDECFQFYTKEEQLAQDDAWKCPHCEALQRGMVKLSLWTLPDILIIHLKRF--CQVGEKRNKLSTLVRFPLSgLDMAPHVAQRGAGP 616
           *****************************************************..788899***********************66665 PP
   S: 273  ke....................kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
                                 +  Y+L+av++H+Gsl++GHY+ay++n  +g+W+ +dDs+V++++e+ev++   + aY+lfY++r
   Q: 617  PAatgpwpswkqpaclpagyplDSLYDLYAVCNHHGSLQGGHYTAYCRNsLDGQWYSYDDSTVEPLPEDEVNT---RGAYILFYQKR 700
           5578888888888899999999***************************55788*******************...********985 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

RRSQVGGPRG ALPGGPQPSP RRASLGESSF GPSSPSPAQP RTQPRPSAGY PEEERPPGAQ 60
PQRQPQPQPQ PQPQPQPQPP AGDGARPPGA QGLKNHGNTC FMNAVVQCLS NTDLLAEFLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGCGCTCGC AGGTGGGAGG ACCCCGCGGC GCGCTCCCCG GCGGGCCCCA GCCCAGCCCC 60
CGGCGCGCGT CTCTTGGAGA ATCTTCCTTT GGCCCATCTT CACCTTCCCC TGCACGTAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001922	Ailuropoda melanoleuca	82.26	0.00e+00	1576.00
IUUC-Aca-004436	Anolis carolinensis	50.32	0.00e+00	763.00
IUUC-Ame-011153	Astyanax mexicanus	54.15	0.00e+00	850.00
IUUC-Bta-013560	Bos taurus	78.37	0.00e+00	1558.00
IUUC-Cja-018737	Callithrix jacchus	75.79	0.00e+00	1509.00
IUUC-Csa-023656	Chlorocebus sabaeus	77.17	0.00e+00	1514.00
IUUC-Cho-024864	Choloepus hoffmanni	69.83	0.00e+00	902.00
IUUC-Dre-028066	Danio rerio	48.12	0.00e+00	892.00
IUUC-Dno-028855	Dasypus novemcinctus	73.65	0.00e+00	1340.00
IUUC-Dor-030475	Dipodomys ordii	83.97	0.00e+00	700.00
IUUC-Dme-032088	Drosophila melanogaster	37.22	2.00e-112	400.00
IUUC-Eca-034147	Equus caballus	83.73	0.00e+00	1409.00
IUUC-Eeu-034703	Erinaceus europaeus	67.55	3.00e-131	462.00
IUUC-Fca-036550	Felis catus	77.27	0.00e+00	1337.00
IUUC-Gac-042087	Gasterosteus aculeatus	49.95	0.00e+00	852.00
IUUC-Ggo-045171	Gorilla gorilla	77.53	0.00e+00	1508.00
IUUC-Hsa-045961	Homo sapiens	77.60	0.00e+00	1515.00
IUUC-Loc-052852	Lepisosteus oculatus	60.65	0.00e+00	908.00
IUUC-Laf-054033	Loxodonta africana	75.76	0.00e+00	1463.00
IUUC-Mcc-055431	Macaca mulatta	77.55	0.00e+00	1515.00
IUUC-Mmr-061035	Microcebus murinus	78.41	0.00e+00	1516.00
IUUC-Mdo-062172	Monodelphis domestica	65.76	0.00e+00	960.00
IUUC-Mmu-063966	Mus musculus	72.99	0.00e+00	1421.00
IUUC-Mpu-066307	Mustela putorius furo	82.73	0.00e+00	1571.00
IUUC-Nle-070172	Nomascus leucogenys	77.74	0.00e+00	1521.00
IUUC-Opr-070499	Ochotona princeps	68.32	0.00e+00	1298.00
IUUC-Ont-071920	Oreochromis niloticus	59.68	0.00e+00	853.00
IUUC-Ocu-074014	Oryctolagus cuniculus	77.09	0.00e+00	1131.00
IUUC-Ola-086360	Oryzias latipes	49.53	0.00e+00	869.00
IUUC-Oga-088202	Otolemur garnettii	75.38	0.00e+00	1488.00
IUUC-Oar-089819	Ovis aries	78.00	0.00e+00	1505.00
IUUC-Ptr-091076	Pan troglodytes	77.35	0.00e+00	1511.00
IUUC-Pan-092248	Papio anubis	76.89	0.00e+00	1505.00
IUUC-Pfo-096534	Poecilia formosa	58.53	0.00e+00	798.00
IUUC-Pab-098453	Pongo abelii	75.64	0.00e+00	1459.00
IUUC-Pca-100290	Procavia capensis	57.57	0.00e+00	647.00
IUUC-Pva-102317	Pteropus vampyrus	70.97	0.00e+00	1351.00
IUUC-Rno-104948	Rattus norvegicus	71.25	0.00e+00	1289.00
IUUC-Sha-106558	Sarcophilus harrisii	57.09	0.00e+00	1101.00
IUUC-Sar-113105	Sorex araneus	65.81	0.00e+00	949.00
IUUC-Ssc-115312	Sus scrofa	79.73	0.00e+00	1560.00
IUUC-Tru-117995	Takifugu rubripes	61.47	0.00e+00	865.00
IUUC-Tsy-119325	Tarsius syrichta	71.23	0.00e+00	706.00
IUUC-Tni-120517	Tetraodon nigroviridis	57.37	0.00e+00	822.00
IUUC-Tbe-127439	Tupaia belangeri	60.04	5.00e-112	399.00
IUUC-Ttr-128829	Tursiops truncatus	71.02	0.00e+00	1365.00
IUUC-Vpa-130306	Vicugna pacos	79.09	1.00e-178	620.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence