iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020765

Ensembl Protein ID

ENSCAFP00000036631.1

UniProt Accession

J9NTZ4; J9NTZ4_CANLF

Genbank Protein ID

ENSCAFP00000036631

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03013893

Gene Name

EFCAB8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000031611.1	ENSCAFT00000046031.1	ENSCAFP00000036631.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.60e-20	70.7	372	398
UBD/Beta-Prp	1.80e-42	145.8	374	611

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf.sd.tllvsGsdDgtikvWD 29
           ++ c+++ +d +l+v+G++D  i++W+
   Q: 372  GILCFDYcPDkNLVVTGGYDPLIRLWN 398
           5889999*9*9***************9 PP

UBD/Beta-Prp

   S: 14   tcvkfspdksllatgsrdgtikvwdvttgkl.lrslsgheaevtavkfspdgk.ilvtgseDrtikvwdlstgkcvhtlkghed..... 95
            c ++ pdk+l++tg++d  i++w+ +  k+ ++ ++gh+  vt +  +++ + il++ s+D++i+vwd++++ c+++++g+ +     
   Q: 374  LCFDYCPDKNLVVTGGYDPLIRLWNPFFSKKpVWMMKGHQTSVTHILVNSKNSsILLSISKDKNIRVWDMQDYICLQSFSGKLFalgnc 462
           46889********************7765555999**********998887667**************************886511111 PP
   S: 96   svlslsfspsg.dklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtl..tggh 179
            ++s+ f+++  + + s+ +  +++ + let+   +    + + ++  c+v+ ++  + +vsG+l + v +W +ktgk + ++  tg++
   Q: 463  PITSVYFHKNEdSLICSTFSIGILKGY-LETEGPGKPrERTTTYSTPLCAVLYSKIfKQVVSGCLSSLVSVWEIKTGKRMMEFsvTGDQ 550
           68889****883555566678888889.55555554236777778899999999999**************************776666 PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsg 240
           +   + + +d++ ++l++g +dgt+k+w++  gec+ t+ + ++   s  ++ n+ ++v+g
   Q: 551  QVELTTMCLDESERCLLTGLRDGTIKMWNYTVGECLLTFPNPDQLEISGIVHMNKVFYVTG 611
           66666677********************************999887777777566665555 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MSKPSSSEDL RESPQSQEAS TPGGFQKNEE VLSSPASTVT LSHHESQLFT QLHMVKMEKM 60
FEDDVDSTGA LDMKTFIKAI KKILSNASDE MLEALFLKVD TDCNGSITWQ EYVDYVMREL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGCTTAA CTGTAAAATA TCCCCTTTTA TTATTCTTAG AGGACTCACT GGTTTCTTTT 60
CATGAGCAAA CAGTACCTCT TCTTAAAGTG CACTTTGCAG AAGTTTCACC CCTTTTCCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005509--F:calcium ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cja-020006	Callithrix jacchus	69.83	0.00e+00	1118.00
IUUC-Cin-025265	Ciona intestinalis	27.31	4.00e-71	263.00
IUUC-Dno-029238	Dasypus novemcinctus	62.59	0.00e+00	1555.00
IUUC-Dme-031984	Drosophila melanogaster	22.66	1.00e-50	195.00
IUUC-Ggo-044932	Gorilla gorilla	64.81	0.00e+00	1711.00
IUUC-Hsa-046963	Homo sapiens	65.38	0.00e+00	1712.00
IUUC-Lch-050281	Latimeria chalumnae	39.54	1.00e-156	546.00
IUUC-Loc-052029	Lepisosteus oculatus	41.34	2.00e-156	546.00
IUUC-Laf-054508	Loxodonta africana	76.83	0.00e+00	707.00
IUUC-Mcc-054635	Macaca mulatta	64.99	0.00e+00	1716.00
IUUC-Mmr-061370	Microcebus murinus	63.40	0.00e+00	1431.00
IUUC-Mdo-061862	Monodelphis domestica	47.82	0.00e+00	1051.00
IUUC-Mmu-063271	Mus musculus	75.94	8.00e-163	566.00
IUUC-Mpu-066224	Mustela putorius furo	80.09	0.00e+00	1971.00
IUUC-Ocu-074664	Oryctolagus cuniculus	69.84	0.00e+00	1370.00
IUUC-Ola-086449	Oryzias latipes	30.84	2.00e-34	140.00
IUUC-Oar-089288	Ovis aries	69.13	0.00e+00	1766.00
IUUC-Psi-093985	Pelodiscus sinensis	40.27	1.00e-123	437.00
IUUC-Pfo-097353	Poecilia formosa	26.88	7.00e-55	208.00
IUUC-Ssc-115233	Sus scrofa	82.08	8.00e-85	306.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence