iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093041

Ensembl Protein ID

ENSPSIP00000012413.1

UniProt Accession

K7FWK3; K7FWK3_PELSI

Genbank Protein ID

ENSPSIP00000012413

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01049373

Gene Name

PPARG

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000011100.1	ENSPSIT00000012474.1	ENSPSIP00000012413.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	91.40	0.00e+00	872.00	IUUC-Hsa-046916

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

FLSGITMVDT EMPFWPINFG ISPVDLSAME DHSHSFDIKP FTTVDFSSIS SPHYEDISIA 60
RTDQTTGDTI NLLKTLPYAG AIKMEPPSPP YFSEKVQLYS KPQEETSNSL MAIECRVCGD 120

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Nucleotide Sequence
(Fasta)

TTCCTATCAG GGATTACAAT GGTCGACACA GAAATGCCAT TTTGGCCCAT TAATTTTGGA 60
ATTAGTCCAG TGGATCTGTC TGCCATGGAA GATCACTCCC ATTCCTTCGA CATAAAGCCC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003077--1Cnucl_rcpt_G
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR022590--PPARgamma_N
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF12577--PPARgamma_N
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01291--PROXISOMPAGR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0090575--C:RNA polymerase II transcription factor complex
GO:0008144--F:drug binding
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0048469--P:cell maturation
GO:0032869--P:cellular response to insulin stimulus
GO:0042593--P:glucose homeostasis
GO:0042953--P:lipoprotein transport
GO:0045713--P:low-density lipoprotein particle receptor biosynthetic process
GO:0010742--P:macrophage derived foam cell differentiation
GO:0030224--P:monocyte differentiation
GO:0010887--P:negative regulation of cholesterol storage
GO:0060336--P:negative regulation of interferon-gamma-mediated signaling pathway
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0048662--P:negative regulation of smooth muscle cell proliferation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0035357--P:peroxisome proliferator activated receptor signaling pathway
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0008217--P:regulation of blood pressure
GO:0055098--P:response to low-density lipoprotein particle
GO:0032526--P:response to retinoic acid
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001214	Ailuropoda melanoleuca	91.04	0.00e+00	869.00
IUUC-Aca-005129	Anolis carolinensis	91.21	0.00e+00	878.00
IUUC-Ame-010818	Astyanax mexicanus	64.57	0.00e+00	630.00
IUUC-Bta-013226	Bos taurus	90.57	0.00e+00	863.00
IUUC-Cja-019236	Callithrix jacchus	91.61	0.00e+00	874.00
IUUC-Cfa-020281	Canis familiaris	91.18	0.00e+00	869.00
IUUC-Cpo-021587	Cavia porcellus	88.54	0.00e+00	850.00
IUUC-Csa-023400	Chlorocebus sabaeus	91.16	0.00e+00	865.00
IUUC-Cho-024593	Choloepus hoffmanni	80.13	0.00e+00	746.00
IUUC-Dre-028176	Danio rerio	61.19	2.00e-153	535.00
IUUC-Dno-029063	Dasypus novemcinctus	89.96	0.00e+00	862.00
IUUC-Ete-032520	Echinops telfairi	88.49	0.00e+00	837.00
IUUC-Fca-035935	Felis catus	91.40	0.00e+00	872.00
IUUC-Fal-037524	Ficedula albicollis	92.84	0.00e+00	885.00
IUUC-Gga-041223	Gallus gallus	93.05	0.00e+00	884.00
IUUC-Gac-042156	Gasterosteus aculeatus	61.80	0.00e+00	636.00
IUUC-Ggo-045265	Gorilla gorilla	91.40	0.00e+00	872.00
IUUC-Hsa-046916	Homo sapiens	91.40	0.00e+00	872.00
IUUC-Lch-049759	Latimeria chalumnae	79.80	0.00e+00	663.00
IUUC-Loc-051870	Lepisosteus oculatus	74.17	0.00e+00	742.00
IUUC-Laf-054483	Loxodonta africana	90.38	0.00e+00	864.00
IUUC-Meu-056587	Macropus eugenii	90.38	0.00e+00	834.00
IUUC-Mga-059530	Meleagris gallopavo	93.05	0.00e+00	884.00
IUUC-Mmr-060576	Microcebus murinus	90.15	0.00e+00	857.00
IUUC-Mdo-061854	Monodelphis domestica	90.95	0.00e+00	862.00
IUUC-Mmu-063724	Mus musculus	90.36	0.00e+00	864.00
IUUC-Mpu-066888	Mustela putorius furo	90.95	0.00e+00	896.00
IUUC-Mlu-067978	Myotis lucifugus	90.99	0.00e+00	900.00
IUUC-Nle-070069	Nomascus leucogenys	91.19	0.00e+00	870.00
IUUC-Opr-070630	Ochotona princeps	88.86	0.00e+00	696.00
IUUC-Ont-071399	Oreochromis niloticus	60.81	0.00e+00	632.00
IUUC-Ocu-074862	Oryctolagus cuniculus	89.73	0.00e+00	858.00
IUUC-Ola-087266	Oryzias latipes	56.61	4.00e-160	557.00
IUUC-Oga-089143	Otolemur garnettii	90.36	0.00e+00	862.00
IUUC-Oar-089725	Ovis aries	90.57	0.00e+00	862.00
IUUC-Ptr-091580	Pan troglodytes	91.40	0.00e+00	872.00
IUUC-Pfo-097438	Poecilia formosa	59.89	3.00e-179	621.00
IUUC-Pab-098333	Pongo abelii	90.36	0.00e+00	855.00
IUUC-Pca-100861	Procavia capensis	90.15	0.00e+00	859.00
IUUC-Pva-102186	Pteropus vampyrus	80.50	0.00e+00	745.00
IUUC-Rno-105583	Rattus norvegicus	90.15	0.00e+00	862.00
IUUC-Sha-107484	Sarcophilus harrisii	90.02	0.00e+00	864.00
IUUC-Sar-112996	Sorex araneus	81.05	3.00e-177	614.00
IUUC-Ssc-115945	Sus scrofa	90.78	0.00e+00	866.00
IUUC-Tsy-119098	Tarsius syrichta	80.92	0.00e+00	743.00
IUUC-Tni-120902	Tetraodon nigroviridis	61.64	6.00e-173	600.00
IUUC-Tbe-127225	Tupaia belangeri	68.55	4.00e-173	600.00
IUUC-Ttr-129292	Tursiops truncatus	90.57	0.00e+00	863.00
IUUC-Vpa-130378	Vicugna pacos	84.46	0.00e+00	675.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence