iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133212

Ensembl Protein ID

ENSXMAP00000008514.1

UniProt Accession

M4A220; M4A220_XIPMA

Genbank Protein ID

ENSXMAP00000008514

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01001142

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000008485.1	ENSXMAT00000008527.1	ENSXMAP00000008514.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	9.30e-14	51.3	3	61
E3 adaptor/Cullin RING/DCX/DWD	7.30e-33	111.2	391	424
UBD/Beta-Prp	9.30e-53	179.4	232	462

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 6    flCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrl 64
           ++C+I +e++++P+++p s+++++r+ Iek++a++g+ +P+++qpl+ee+lv+ ++ + +
   Q: 3    LVCAICNEVPEHPCISPvSNHVFERRLIEKYIAENGT-DPMNGQPLSEEQLVDIKVTHPI 61
           68**********************************9.**************99987765 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           gH+++vt++af  ++ +l++G+ D ++k+WDlr+
   Q: 391  GHSGPVTSIAFseNGYYLATGAQDSSVKLWDLRK 424
           8**********976699**************986 PP

UBD/Beta-Prp

   S: 19   spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgd 107
             d++ ++tg++d+ + v+d  +++ +++l+gh ++vt+v ++p++++  ++s D+ti+vw++  g c++++++he+ v+ ls++++gd
   Q: 232  PSDTNKVLTGGADKNVVVFDKNEEQIVATLKGHAKKVTSVIYHPSQSVVFSASPDATIRVWSVTGGNCIQVVRAHEAGVTGLSLHATGD 320
           568899*********************************************************************************** PP
   S: 108  klvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkel 195
           +l+s s+d++    d++tg +l + t++    + +c+++hpdg ++ +G++D+++++Wdlk  + +  + g h ++v+s++f++ng +l
   Q: 321  YLLSSSEDQYWAFSDIQTGRVLTKvTDESAGCALTCAQFHPDGLIFGTGTADSQIKIWDLKERTNVANFPG-HSGPVTSIAFSENGYYL 408
           **********************997777777899************************************9.***************** PP
   S: 196  vsgsldgtvklwdlqtgecvrtlng.htdnvksvrfspnderlvsgssDgsiri 248
           ++g++d++vklwdl++ +  +t     +  vks+ f++ +++l++g+sD  ++i
   Q: 409  ATGAQDSSVKLWDLRKLKNFKTISLdNNYEVKSLVFDQSGTYLAVGGSDIRVYI 462
           ***************888888777537799*******************88877 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MSLVCAICNE VPEHPCISPV SNHVFERRLI EKYIAENGTD PMNGQPLSEE QLVDIKVTHP 60
IRPKAPSATS IPAILKSLQD EWDAVMLHSF TLRQQLQTTR QELSHALYQH DAACRVIARL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTGACGTA TGAGGAAAAC AGCGTAGAAG ACTTAACATC AGTTCCTTTT ATAGCGGCAA 60
TGAAAGGACA GCGTGCCACT TACGATTTTA GCCAAACATA ACTTAGGCAT ACATTACCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013915--Pre-mRNA_splic_Prp19
IPR000772--Ricin_B_lectin
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50231--RICIN_B_LECTIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08606--Prp19
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0043518--P:negative regulation of DNA damage response, signal transduction by p53 class mediator

KEGG

xma:102231739

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000488	Aegilops tauschii	40.97	1.00e-100	361.00
IUUC-Aml-001230	Ailuropoda melanoleuca	82.20	0.00e+00	855.00
IUUC-Atr-002594	Amborella trichopoda	44.53	2.00e-119	422.00
IUUC-Apl-003686	Anas platyrhynchos	77.10	0.00e+00	659.00
IUUC-Aca-005272	Anolis carolinensis	84.95	0.00e+00	901.00
IUUC-Aly-005586	Arabidopsis lyrata	44.21	5.00e-119	421.00
IUUC-Ath-007696	Arabidopsis thaliana	44.23	3.00e-116	412.00
IUUC-Acl-008335	Aspergillus clavatus	37.63	5.00e-70	258.00
IUUC-Afl-008527	Aspergillus flavus	38.19	1.00e-73	270.00
IUUC-Afu-008957	Aspergillus fumigatus	38.40	6.00e-80	291.00
IUUC-Ani-009280	Aspergillus nidulans	39.04	2.00e-68	253.00
IUUC-Ang-009746	Aspergillus niger	37.34	1.00e-68	253.00
IUUC-Aor-009905	Aspergillus oryzae	37.97	4.00e-77	281.00
IUUC-Ate-010412	Aspergillus terreus	36.84	3.00e-64	239.00
IUUC-Ame-011561	Astyanax mexicanus	90.46	3.00e-115	407.00
IUUC-Bgr-012283	Blumeria graminis	32.35	8.00e-56	211.00
IUUC-Bta-013242	Bos taurus	84.36	0.00e+00	901.00
IUUC-Bci-013901	Botrytis cinerea	34.79	2.00e-68	253.00
IUUC-Bdi-014277	Brachypodium distachyon	45.30	6.00e-126	444.00
IUUC-Bol-016207	Brassica oleracea	45.35	8.00e-120	424.00
IUUC-Bra-017650	Brassica rapa	44.77	9.00e-120	423.00
IUUC-Cel-018271	Caenorhabditis elegans	52.86	6.00e-155	540.00
IUUC-Cja-019879	Callithrix jacchus	83.99	0.00e+00	895.00
IUUC-Cfa-020175	Canis familiaris	84.36	0.00e+00	901.00
IUUC-Cpo-022379	Cavia porcellus	84.55	0.00e+00	902.00
IUUC-Cre-022993	Chlamydomonas reinhardtii	40.08	5.00e-100	358.00
IUUC-Csa-023500	Chlorocebus sabaeus	84.36	0.00e+00	901.00
IUUC-Cho-025065	Choloepus hoffmanni	74.36	3.00e-130	457.00
IUUC-Cin-025699	Ciona intestinalis	68.48	2.00e-174	605.00
IUUC-Csv-026128	Ciona savignyi	66.15	0.00e+00	695.00
IUUC-Cgl-026507	Colletotrichum gloeosporioides	33.67	7.00e-65	241.00
IUUC-Cne-026860	Cryptococcus neoformans	36.59	4.00e-92	332.00
IUUC-Dre-028187	Danio rerio	91.88	0.00e+00	912.00
IUUC-Dno-029453	Dasypus novemcinctus	84.36	0.00e+00	900.00
IUUC-Dor-030150	Dipodomys ordii	84.10	7.00e-112	397.00
IUUC-Dse-031220	Dothistroma septosporum	32.56	8.00e-58	218.00
IUUC-Dme-031906	Drosophila melanogaster	66.08	0.00e+00	663.00
IUUC-Ete-033035	Echinops telfairi	73.86	0.00e+00	759.00
IUUC-Eca-033478	Equus caballus	84.16	0.00e+00	899.00
IUUC-Eeu-034974	Erinaceus europaeus	83.28	5.00e-174	603.00
IUUC-Fca-036194	Felis catus	83.90	0.00e+00	892.00
IUUC-Fal-037417	Ficedula albicollis	83.96	0.00e+00	894.00
IUUC-Fox-037922	Fusarium oxysporum	32.73	1.00e-63	237.00
IUUC-Fso-038256	Fusarium solani	34.67	1.00e-67	250.00
IUUC-Gmo-038713	Gadus morhua	94.85	0.00e+00	946.00
IUUC-Ggr-039854	Gaeumannomyces graminis	32.16	2.00e-53	203.00
IUUC-Gga-041143	Gallus gallus	84.16	0.00e+00	897.00
IUUC-Gac-042129	Gasterosteus aculeatus	94.85	0.00e+00	968.00
IUUC-Gma-044273	Glycine max	44.72	8.00e-122	430.00
IUUC-Ggo-045262	Gorilla gorilla	84.36	0.00e+00	901.00
IUUC-Hsa-046036	Homo sapiens	84.36	0.00e+00	901.00
IUUC-Hvu-047442	Hordeum vulgare	44.48	1.00e-66	246.00
IUUC-Itr-048169	Ictidomys tridecemlineatus	83.76	0.00e+00	867.00
IUUC-Lch-050105	Latimeria chalumnae	83.76	0.00e+00	888.00
IUUC-Lpe-050976	Leersia perrieri	45.19	3.00e-122	432.00
IUUC-Loc-052042	Lepisosteus oculatus	79.36	0.00e+00	700.00
IUUC-Lma-053143	Leptosphaeria maculans	34.53	1.00e-66	248.00
IUUC-Laf-053451	Loxodonta africana	81.23	0.00e+00	888.00
IUUC-Mcc-055786	Macaca mulatta	84.36	0.00e+00	901.00
IUUC-Meu-056161	Macropus eugenii	85.89	3.00e-127	448.00
IUUC-Mor-057215	Magnaporthe oryzae	33.07	2.00e-54	206.00
IUUC-Mpo-057419	Magnaporthe poae	31.57	3.00e-50	192.00
IUUC-Mtr-057756	Medicago truncatula	44.42	2.00e-117	415.00
IUUC-Mla-059085	Melampsora laricipopulina	39.11	2.00e-89	323.00
IUUC-Mga-060158	Meleagris gallopavo	79.60	0.00e+00	801.00
IUUC-Mvi-060441	Microbotryum violaceum	38.45	7.00e-82	298.00
IUUC-Mmr-061085	Microcebus murinus	84.36	0.00e+00	901.00
IUUC-Mdo-061804	Monodelphis domestica	84.75	0.00e+00	904.00
IUUC-Mmu-063608	Mus musculus	81.30	0.00e+00	888.00
IUUC-Mac-064972	Musa acuminata	45.17	7.00e-120	424.00
IUUC-Mpu-065700	Mustela putorius furo	84.36	0.00e+00	902.00
IUUC-Mlu-068223	Myotis lucifugus	82.12	0.00e+00	894.00
IUUC-Nfi-068504	Neosartorya fischeri	38.32	4.00e-79	288.00
IUUC-Ncr-068729	Neurospora crassa	34.81	4.00e-62	232.00
IUUC-Nle-069754	Nomascus leucogenys	84.36	0.00e+00	901.00
IUUC-Opr-070621	Ochotona princeps	82.29	0.00e+00	854.00
IUUC-Ont-071377	Oreochromis niloticus	96.04	0.00e+00	951.00
IUUC-Oan-073498	Ornithorhynchus anatinus	61.75	3.00e-107	381.00
IUUC-Ocu-074182	Oryctolagus cuniculus	80.99	0.00e+00	889.00
IUUC-Oba-075509	Oryza barthii	45.49	2.00e-125	442.00
IUUC-Obr-076480	Oryza brachyantha	45.87	2.00e-125	442.00
IUUC-Ogl-077052	Oryza glaberrima	45.49	3.00e-125	442.00
IUUC-Ogu-078919	Oryza glumaepatula	45.49	3.00e-125	442.00
IUUC-Oin-079357	Oryza indica	44.02	1.00e-117	416.00
IUUC-Olo-080376	Oryza longistaminata	45.66	3.00e-113	402.00
IUUC-Ome-081973	Oryza meridionalis	45.08	4.00e-113	401.00
IUUC-Oni-082849	Oryza nivara	45.49	1.00e-125	443.00
IUUC-Opu-083243	Oryza punctata	45.30	2.00e-124	439.00
IUUC-Oru-084613	Oryza rufipogon	46.14	6.00e-125	441.00
IUUC-Osa-085407	Oryza sativa	45.47	1.00e-124	440.00
IUUC-Ola-086566	Oryzias latipes	96.27	0.00e+00	952.00
IUUC-Olu-087757	Ostreococcus lucimarinus	38.25	3.00e-92	332.00
IUUC-Oga-089010	Otolemur garnettii	81.39	0.00e+00	856.00
IUUC-Oar-089638	Ovis aries	84.36	0.00e+00	901.00
IUUC-Ptr-091141	Pan troglodytes	84.36	0.00e+00	901.00
IUUC-Pan-092662	Papio anubis	84.36	0.00e+00	901.00
IUUC-Psi-093777	Pelodiscus sinensis	83.81	0.00e+00	734.00
IUUC-Pno-095115	Phaeosphaeria nodorum	35.79	6.00e-69	254.00
IUUC-Ppa-095841	Physcomitrella patens	45.73	2.00e-123	436.00
IUUC-Pfo-096390	Poecilia formosa	99.80	0.00e+00	981.00
IUUC-Pab-098250	Pongo abelii	84.91	0.00e+00	850.00
IUUC-Pop-099854	Populus trichocarpa	44.89	5.00e-121	427.00
IUUC-Pca-100553	Procavia capensis	83.76	0.00e+00	891.00
IUUC-Ppe-101383	Prunus persica	44.40	1.00e-115	410.00
IUUC-Pva-102189	Pteropus vampyrus	84.36	0.00e+00	901.00
IUUC-Pgr-103304	Puccinia graminis	35.90	4.00e-85	308.00
IUUC-Ptt-103984	Puccinia triticina	36.65	7.00e-90	324.00
IUUC-Pte-104385	Pyrenophora teres	34.39	2.00e-73	269.00
IUUC-Pyt-104697	Pyrenophora triticirepentis	34.39	1.00e-73	270.00
IUUC-Rno-105581	Rattus norvegicus	84.36	0.00e+00	900.00
IUUC-Sha-107071	Sarcophilus harrisii	80.83	0.00e+00	888.00
IUUC-Sja-107697	Schizosaccharomyces japonicus	29.62	9.00e-37	148.00
IUUC-Spo-108315	Schizosaccharomyces pombe	30.72	9.00e-43	167.00
IUUC-Ssl-108628	Sclerotinia sclerotiorum	34.74	3.00e-67	249.00
IUUC-Smo-109648	Selaginella moellendorffii	46.14	3.00e-125	442.00
IUUC-Sit-109873	Setaria italica	45.17	2.00e-122	433.00
IUUC-Sly-111673	Solanum lycopersicum	45.19	1.00e-113	403.00
IUUC-Stu-112125	Solanum tuberosum	44.77	5.00e-112	398.00
IUUC-Sbi-114696	Sorghum bicolor	41.68	3.00e-110	392.00
IUUC-Sre-115134	Sporisorium reilianum	31.78	2.00e-70	259.00
IUUC-Ssc-116260	Sus scrofa	84.16	0.00e+00	900.00
IUUC-Tgu-116533	Taeniopygia guttata	83.96	0.00e+00	895.00
IUUC-Tru-117800	Takifugu rubripes	94.46	0.00e+00	981.00
IUUC-Tsy-118980	Tarsius syrichta	79.80	0.00e+00	815.00
IUUC-Tni-120334	Tetraodon nigroviridis	93.69	0.00e+00	657.00
IUUC-Tca-121807	Theobroma cacao	44.79	4.00e-121	428.00
IUUC-Tre-121920	Trichoderma reesei	33.27	5.00e-63	235.00
IUUC-Tvi-122294	Trichoderma virens	31.93	3.00e-55	209.00
IUUC-Tae-125713	Triticum aestivum	46.15	2.00e-126	445.00
IUUC-Tur-126664	Triticum urartu	41.55	5.00e-116	411.00
IUUC-Tme-127026	Tuber melanosporum	34.67	1.00e-71	263.00
IUUC-Tbe-127582	Tupaia belangeri	83.28	1.00e-173	602.00
IUUC-Ttr-128313	Tursiops truncatus	83.96	0.00e+00	891.00
IUUC-Uma-129626	Ustilago maydis	32.72	7.00e-73	268.00
IUUC-Vda-129699	Verticillium dahliae	33.53	3.00e-66	246.00
IUUC-Vpa-130593	Vicugna pacos	85.46	0.00e+00	811.00
IUUC-Vvi-131668	Vitis vinifera	44.40	5.00e-121	427.00
IUUC-Xtr-132186	Xenopus tropicalis	80.45	0.00e+00	722.00
IUUC-Yli-134607	Yarrowia lipolytica	53.79	1.00e-39	154.00
IUUC-Zma-135662	Zea mays	45.19	3.00e-124	438.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence