iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-054941

Ensembl Protein ID

ENSMMUP00000009285.2

UniProt Accession

F7ES08; F7ES08_MACMU

Genbank Protein ID

AFE64393.1; EHH23441.1

Protein Name

Zinc finger and BTB domain-containing protein 16

Genbank Nucleotide ID

JSUE03013446; CM001266

Gene Name

ZBTB16; EGK_06914

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000007085.3	ENSMMUT00000009890.3	ENSMMUP00000009285.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	2.90e-09	38.2	34	94

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv++ v+ +ef+ah+ vLa  S++F+ lf        ++  ++++ ++p+ f+++l++ Yt +l+ 
   Q: 34   CDVVIMVDSQEFHAHRTVLACTSKMFEILFHR------NSQHYTLDFLSPKTFQQILEYAYTATLQA 94
           8*****************************33......3668889989***************9985 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MDLTKMGMIQ LQNPSHPTGL LCKANQMRLA GTLCDVVIMV DSQEFHAHRT VLACTSKMFE 60
ILFHRNSQHY TLDFLSPKTF QQILEYAYTA TLQAKAEDLD DLLYAAEILE IEYLEEQCLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGCCGGGG CCTTGCAGGG GAGGGGGCTC GGCGTTGACG TGGGACGCGG CGGAGGCGCA 60
GCNNNNNNNN NNNNNNNNNN NNCTCGCAGC AGAGAGGAGT TGAGGGCGAT GAGAGCGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0016607--C:nuclear speck
GO:0016605--C:PML body
GO:0017053--C:transcriptional repressor complex
GO:0046872--F:metal ion binding
GO:0000980--F:RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001206--F:transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0009952--P:anterior/posterior pattern specification
GO:0051216--P:cartilage development
GO:0007417--P:central nervous system development
GO:0035116--P:embryonic hindlimb morphogenesis
GO:0009880--P:embryonic pattern specification
GO:0035136--P:forelimb morphogenesis
GO:0030097--P:hemopoiesis
GO:0048133--P:male germ-line stem cell asymmetric division
GO:0001823--P:mesonephros development
GO:0008285--P:negative regulation of cell proliferation
GO:0045638--P:negative regulation of myeloid cell differentiation
GO:0043065--P:positive regulation of apoptotic process
GO:0032332--P:positive regulation of chondrocyte differentiation
GO:0045600--P:positive regulation of fat cell differentiation
GO:0051138--P:positive regulation of NK T cell differentiation
GO:0045778--P:positive regulation of ossification
GO:0045893--P:positive regulation of transcription, DNA-templated

KEGG

mcc:695064

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001304	Ailuropoda melanoleuca	97.62	0.00e+00	1281.00
IUUC-Apl-003955	Anas platyrhynchos	86.78	0.00e+00	1164.00
IUUC-Aca-005156	Anolis carolinensis	72.77	2.00e-149	521.00
IUUC-Ame-011629	Astyanax mexicanus	77.71	0.00e+00	947.00
IUUC-Bta-012807	Bos taurus	96.29	0.00e+00	1281.00
IUUC-Cja-019347	Callithrix jacchus	99.26	0.00e+00	1350.00
IUUC-Cfa-020219	Canis familiaris	96.14	0.00e+00	1253.00
IUUC-Cpo-021404	Cavia porcellus	94.50	0.00e+00	1236.00
IUUC-Csa-023837	Chlorocebus sabaeus	99.85	0.00e+00	1359.00
IUUC-Cho-024691	Choloepus hoffmanni	84.66	0.00e+00	851.00
IUUC-Dre-027842	Danio rerio	79.09	0.00e+00	992.00
IUUC-Dno-029711	Dasypus novemcinctus	97.18	0.00e+00	1291.00
IUUC-Ete-032980	Echinops telfairi	95.99	0.00e+00	1281.00
IUUC-Eca-033437	Equus caballus	98.22	0.00e+00	1308.00
IUUC-Fca-035631	Felis catus	95.50	0.00e+00	726.00
IUUC-Fal-037329	Ficedula albicollis	82.03	0.00e+00	1018.00
IUUC-Gmo-039421	Gadus morhua	72.27	0.00e+00	851.00
IUUC-Gga-041063	Gallus gallus	86.18	0.00e+00	1132.00
IUUC-Gac-041889	Gasterosteus aculeatus	71.74	0.00e+00	867.00
IUUC-Ggo-045452	Gorilla gorilla	99.70	0.00e+00	1356.00
IUUC-Hsa-046824	Homo sapiens	99.55	0.00e+00	1357.00
IUUC-Itr-048417	Ictidomys tridecemlineatus	95.10	0.00e+00	1274.00
IUUC-Lch-049446	Latimeria chalumnae	72.54	5.00e-162	563.00
IUUC-Loc-051811	Lepisosteus oculatus	80.53	0.00e+00	1026.00
IUUC-Laf-053594	Loxodonta africana	97.18	0.00e+00	1328.00
IUUC-Mga-059231	Meleagris gallopavo	86.48	0.00e+00	1131.00
IUUC-Mmr-061486	Microcebus murinus	93.53	0.00e+00	1232.00
IUUC-Mdo-063075	Monodelphis domestica	91.99	0.00e+00	1255.00
IUUC-Mmu-063142	Mus musculus	96.88	0.00e+00	1315.00
IUUC-Mpu-066057	Mustela putorius furo	96.88	0.00e+00	1294.00
IUUC-Mlu-067412	Myotis lucifugus	95.26	0.00e+00	1298.00
IUUC-Nle-069210	Nomascus leucogenys	99.70	0.00e+00	1356.00
IUUC-Opr-070631	Ochotona princeps	91.99	0.00e+00	1203.00
IUUC-Ont-071326	Oreochromis niloticus	76.11	0.00e+00	918.00
IUUC-Oan-073311	Ornithorhynchus anatinus	72.57	1.00e-80	292.00
IUUC-Ocu-074156	Oryctolagus cuniculus	97.18	0.00e+00	1272.00
IUUC-Ola-086952	Oryzias latipes	58.58	0.00e+00	674.00
IUUC-Oga-088714	Otolemur garnettii	98.81	0.00e+00	1299.00
IUUC-Ptr-090490	Pan troglodytes	98.83	0.00e+00	1186.00
IUUC-Pan-092563	Papio anubis	100.00	0.00e+00	1361.00
IUUC-Psi-093644	Pelodiscus sinensis	85.44	0.00e+00	1122.00
IUUC-Pma-094677	Petromyzon marinus	50.07	4.00e-158	551.00
IUUC-Pfo-096399	Poecilia formosa	75.78	0.00e+00	920.00
IUUC-Pab-097934	Pongo abelii	99.83	0.00e+00	1196.00
IUUC-Pca-101003	Procavia capensis	90.04	0.00e+00	1207.00
IUUC-Pva-102802	Pteropus vampyrus	97.32	0.00e+00	1149.00
IUUC-Rno-105871	Rattus norvegicus	96.29	0.00e+00	1309.00
IUUC-Sha-107295	Sarcophilus harrisii	91.54	0.00e+00	1189.00
IUUC-Sar-113057	Sorex araneus	91.47	0.00e+00	669.00
IUUC-Ssc-116179	Sus scrofa	96.68	0.00e+00	763.00
IUUC-Tgu-116805	Taeniopygia guttata	73.88	0.00e+00	832.00
IUUC-Tru-118282	Takifugu rubripes	58.96	0.00e+00	692.00
IUUC-Tni-120296	Tetraodon nigroviridis	60.03	0.00e+00	711.00
IUUC-Tbe-127742	Tupaia belangeri	89.27	0.00e+00	1170.00
IUUC-Ttr-128285	Tursiops truncatus	96.73	0.00e+00	1289.00
IUUC-Xtr-132970	Xenopus tropicalis	77.15	0.00e+00	1004.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence