iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-087278

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

BAAF04022191

Gene Name

ube2kb; ube2k

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000005661.1	ENSORLT00000007119.1	ENSORLP00000007118.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.00e-45	155.2	8	146
UBD/UBC-like/UBD_UBC	5.20e-72	240.7	8	149
UBD/Alpha-Helix/UBA	4.60e-10	39.6	162	199

Active Site

Position(s)	Description	Evidence
92	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkel...ekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsi 85
           R+k+e+ke+   e++++++i++++vde ++te++ +i Gp+dtpYegg ++lei++pe+YPf+PPkv+f+tki+hPn+++  G++Cl+i
   Q: 8    RIKREFKEVlksEETSKNQIKVDLVDE-NFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVtGAICLDI 95
           7888888873335556699********.9***************************************************99******* PP
   S: 86   lkeeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           lk  ++W +a+++++vlls+q+lla ++p++p+++ +a+++k+n+e++k+++r
   Q: 96   LK--DQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQFKQNPEMFKQTAR 146
           *9..**********************************************986 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeea...qisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpnins.ngsicldil 85
           rik+e+k++l++ee+   qi++dlvd++++elr++iagppd+pyegg+++l+ik+p++ypf+ppkv+fitki+hpni+s +g+icldil
   Q: 8    RIKREFKEVLKSEETsknQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSvTGAICLDIL 96
           8*************9999*********************************************************************** PP
   S: 86   rsqwsaaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           ++qw+aa+tl++vllsl++lla+aepddp++a++a+++k+++e++k++ar+w+
   Q: 97   KDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQFKQNPEMFKQTARLWS 149
           ****************************************************5 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraannnleaAveyLld 40
           ++ k+++l++MGFd+++++ aL + ++++e A+e+Ll+
   Q: 162  YTRKIDKLCAMGFDKNAVIAALSSKSWDVETATELLLS 199
           6789********************************97 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MANIAVQRIK REFKEVLKSE ETSKNQIKVD LVDENFTELR GEIAGPPDTP YEGGRYQLEI 60
KIPETYPFNP PKVRFITKIW HPNISSVTGA ICLDILKDQW AAAMTLRTVL LSLQALLAAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGACACACA GCCAGGTAGA CTGCCGACAG CGACCGCGAG GCTGAGCTCC CTCTGGAGTG 60
AAAAGAAGCG CCGGGCGCTG AAAGTGAAAC GAGATCGATA ACAGTAAGGT ATCCCGCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50030--UBA
PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00627--UBA
PF00179--UQ_con

SMART

SM00165--UBA

Gene Ontology

GO:0005524--F:ATP binding

KEGG

ola:101166933

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008189	Aspergillus clavatus	49.03	8.00e-28	117.00
IUUC-Afl-008489	Aspergillus flavus	41.40	4.00e-29	121.00
IUUC-Afu-008850	Aspergillus fumigatus	41.12	4.00e-30	124.00
IUUC-Ani-009361	Aspergillus nidulans	50.00	2.00e-26	112.00
IUUC-Ang-009548	Aspergillus niger	39.37	2.00e-27	115.00
IUUC-Aor-010105	Aspergillus oryzae	41.40	4.00e-29	121.00
IUUC-Ate-010389	Aspergillus terreus	40.55	6.00e-29	120.00
IUUC-Bgr-012255	Blumeria graminis	47.77	1.00e-33	136.00
IUUC-Bci-013806	Botrytis cinerea	40.55	6.00e-37	147.00
IUUC-Cre-022987	Chlamydomonas reinhardtii	48.47	6.00e-42	163.00
IUUC-Cgl-026449	Colletotrichum gloeosporioides	40.96	1.00e-34	139.00
IUUC-Dse-031335	Dothistroma septosporum	50.32	1.00e-36	146.00
IUUC-Dme-032003	Drosophila melanogaster	69.85	3.00e-73	267.00
IUUC-Fox-037969	Fusarium oxysporum	42.46	9.00e-34	136.00
IUUC-Fso-038296	Fusarium solani	42.00	6.00e-36	143.00
IUUC-Kpa-049297	Komagataella pastoris	49.06	2.00e-34	139.00
IUUC-Lch-050588	Latimeria chalumnae	69.19	2.00e-76	278.00
IUUC-Lma-052949	Leptosphaeria maculans	39.81	2.00e-37	149.00
IUUC-Nfi-068517	Neosartorya fischeri	41.12	4.00e-30	124.00
IUUC-Ncr-068749	Neurospora crassa	40.98	3.00e-39	154.00
IUUC-Ont-071433	Oreochromis niloticus	99.00	3.00e-109	387.00
IUUC-Pma-094115	Petromyzon marinus	82.91	7.00e-90	322.00
IUUC-Pno-095102	Phaeosphaeria nodorum	41.71	7.00e-40	156.00
IUUC-Pfo-096940	Poecilia formosa	99.00	3.00e-109	387.00
IUUC-Pte-104370	Pyrenophora teres	40.74	5.00e-38	150.00
IUUC-Pyt-104592	Pyrenophora triticirepentis	40.28	2.00e-37	148.00
IUUC-Ssl-108609	Sclerotinia sclerotiorum	41.94	2.00e-40	158.00
IUUC-Smo-109656	Selaginella moellendorffii	49.48	4.00e-41	160.00
IUUC-Sly-110978	Solanum lycopersicum	48.22	1.00e-44	172.00
IUUC-Stu-112088	Solanum tuberosum	48.22	5.00e-45	173.00
IUUC-Tru-118618	Takifugu rubripes	94.50	4.00e-104	370.00
IUUC-Tre-122053	Trichoderma reesei	35.82	3.00e-31	128.00
IUUC-Tvi-122533	Trichoderma virens	37.00	7.00e-32	130.00
IUUC-Xtr-132710	Xenopus tropicalis	79.70	2.00e-92	331.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence