iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-087986

Ensembl Protein ID

ENSOGAP00000016871.1

UniProt Accession

H0XL81; H0XL81_OTOGA

Genbank Protein ID

ENSOGAP00000016871

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03180008

Gene Name

RBCK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000031008.1	ENSOGAT00000029942.1	ENSOGAP00000016871.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	2.90e-11	42.7	195	221
ULD/UDP/UBQ/UBQ_Other	5.00e-06	26.3	61	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 3    aqWaCsaCTflNePeavkCemCsrpRg 29
            +W+C+ CTf+N+P +++CemC+r R+
   Q: 195  VGWQCPGCTFINKPTRPGCEMCCRARP 221
           68************************8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 5    vksldgseltlk..vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglk 62
           v+++   + t++  v  ++tVa LK++++   g+pp+ q++++ G+ L +d  tL ++g++
   Q: 61   VEDAHLHTVTIWltVRTDMTVASLKDMVFLDYGFPPALQQWVI-GQRLaRDQETLHSHGVR 120
           5556665666667689999************************.55555*********996 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MDEKTKKAEE MALRLTRAVA GGDERVAIQC AIWLAEQRVP LNVKLKPEAS PTQDIRLWVS 60
VEDAHLHTVT IWLTVRTDMT VASLKDMVFL DYGFPPALQQ WVIGQRLARD QETLHSHGVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACGAGA AGACCAAGAA AGGTGGGCAC AGACTGGAGA ATGCTGCGGG CCTTCAGGAG 60
GGAAGTGGGC TGTGGCGGGA ACTGACCTCG CCTCACCCAA AAGGGATGGG TGAACAAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR002867--IBR_dom
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR027370--Znf-RING_LisH
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50053--UBIQUITIN_2
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00547--ZnF_RBZ

Gene Ontology

GO:0071797--C:LUBAC complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060546--P:negative regulation of necroptotic process
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0042346--P:positive regulation of NF-kappaB import into nucleus
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0097039--P:protein linear polyubiquitination
GO:0050852--P:T cell receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001540	Ailuropoda melanoleuca	90.00	0.00e+00	842.00
IUUC-Apl-003627	Anas platyrhynchos	71.11	2.00e-14	70.10
IUUC-Aca-004507	Anolis carolinensis	63.00	9.00e-150	523.00
IUUC-Ame-011008	Astyanax mexicanus	52.46	1.00e-140	493.00
IUUC-Bta-013247	Bos taurus	92.16	0.00e+00	857.00
IUUC-Bci-013637	Botrytis cinerea	28.57	9.00e-14	72.40
IUUC-Cja-018880	Callithrix jacchus	93.14	0.00e+00	870.00
IUUC-Cfa-020477	Canis familiaris	92.16	0.00e+00	862.00
IUUC-Cpo-021558	Cavia porcellus	87.84	0.00e+00	819.00
IUUC-Csa-024129	Chlorocebus sabaeus	92.75	0.00e+00	853.00
IUUC-Cin-025630	Ciona intestinalis	39.05	1.00e-78	287.00
IUUC-Csv-026069	Ciona savignyi	50.00	3.00e-71	261.00
IUUC-Dre-027591	Danio rerio	52.14	6.00e-140	490.00
IUUC-Dno-029015	Dasypus novemcinctus	90.39	0.00e+00	826.00
IUUC-Dor-030313	Dipodomys ordii	80.08	0.00e+00	721.00
IUUC-Ete-032908	Echinops telfairi	79.80	0.00e+00	723.00
IUUC-Eca-034295	Equus caballus	75.75	0.00e+00	713.00
IUUC-Eeu-034454	Erinaceus europaeus	83.73	2.00e-109	389.00
IUUC-Fca-036380	Felis catus	92.75	0.00e+00	864.00
IUUC-Fal-037440	Ficedula albicollis	55.93	3.00e-15	72.40
IUUC-Gmo-038561	Gadus morhua	54.46	2.00e-119	422.00
IUUC-Gga-040198	Gallus gallus	38.80	9.00e-29	120.00
IUUC-Gac-041319	Gasterosteus aculeatus	52.53	1.00e-133	469.00
IUUC-Ggo-044456	Gorilla gorilla	64.42	1.00e-148	519.00
IUUC-Hsa-045738	Homo sapiens	93.73	0.00e+00	854.00
IUUC-Itr-049042	Ictidomys tridecemlineatus	89.80	0.00e+00	819.00
IUUC-Lch-050269	Latimeria chalumnae	44.76	5.00e-111	395.00
IUUC-Loc-052776	Lepisosteus oculatus	51.41	5.00e-136	478.00
IUUC-Laf-054269	Loxodonta africana	88.63	0.00e+00	827.00
IUUC-Mcc-055669	Macaca mulatta	93.33	0.00e+00	854.00
IUUC-Mga-059615	Meleagris gallopavo	54.69	8.00e-17	77.80
IUUC-Mmr-061562	Microcebus murinus	93.60	0.00e+00	754.00
IUUC-Mdo-062263	Monodelphis domestica	75.78	0.00e+00	730.00
IUUC-Mmu-064325	Mus musculus	89.02	0.00e+00	812.00
IUUC-Mpu-066385	Mustela putorius furo	92.16	0.00e+00	859.00
IUUC-Mlu-067000	Myotis lucifugus	90.00	0.00e+00	820.00
IUUC-Nle-069812	Nomascus leucogenys	93.14	0.00e+00	847.00
IUUC-Opr-070575	Ochotona princeps	95.10	5.00e-108	384.00
IUUC-Ont-072405	Oreochromis niloticus	49.02	6.00e-133	467.00
IUUC-Ocu-074358	Oryctolagus cuniculus	79.46	0.00e+00	748.00
IUUC-Ola-086403	Oryzias latipes	52.81	4.00e-137	481.00
IUUC-Oar-089600	Ovis aries	89.80	0.00e+00	871.00
IUUC-Ptr-091224	Pan troglodytes	93.53	0.00e+00	852.00
IUUC-Pan-092739	Papio anubis	93.53	0.00e+00	857.00
IUUC-Pma-094407	Petromyzon marinus	48.05	5.00e-126	444.00
IUUC-Pfo-097161	Poecilia formosa	52.89	7.00e-132	463.00
IUUC-Pab-098627	Pongo abelii	93.53	0.00e+00	847.00
IUUC-Pca-100641	Procavia capensis	89.52	0.00e+00	774.00
IUUC-Pva-102670	Pteropus vampyrus	92.16	0.00e+00	843.00
IUUC-Pte-104234	Pyrenophora teres	25.97	1.00e-12	67.80
IUUC-Rno-105504	Rattus norvegicus	88.04	0.00e+00	805.00
IUUC-Sha-107342	Sarcophilus harrisii	75.78	0.00e+00	752.00
IUUC-Sar-113425	Sorex araneus	87.21	6.00e-112	397.00
IUUC-Ssc-115904	Sus scrofa	93.06	2.00e-89	321.00
IUUC-Tru-118096	Takifugu rubripes	50.98	6.00e-134	470.00
IUUC-Tni-119873	Tetraodon nigroviridis	49.22	3.00e-133	468.00
IUUC-Tbe-127578	Tupaia belangeri	90.07	0.00e+00	683.00
IUUC-Ttr-129107	Tursiops truncatus	92.55	0.00e+00	841.00
IUUC-Vpa-130353	Vicugna pacos	92.71	3.00e-112	398.00
IUUC-Xtr-132168	Xenopus tropicalis	41.65	4.00e-91	328.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence