iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037209

Ensembl Protein ID

ENSFALP00000015727.1

UniProt Accession

U3KL23; U3KL23_FICAL

Genbank Protein ID

ENSFALP00000015727

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01011393

Gene Name

TOPORS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000015114.1	ENSFALT00000015792.1	ENSFALP00000015727.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.10e-09	36.0	32	71

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl++f++  ++ +C H f++ C+q w      s++++ CPlC+
   Q: 32   CPICLDRFDNVAYLDRCLHRFCFRCVQEW------SKNKAECPLCK 71
           **********888899*************......**********7 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MTSDKEFAEN SNFSPKASTS KLPTDASPDS KCPICLDRFD NVAYLDRCLH RFCFRCVQEW 60
SKNKAECPLC KQPFFSIFHT IRAEDDFKEY ILSPLETSSF ASPDGRRFRY RTTLTRERRT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTTCAG ATAAGGAGTT TGCAGAAAAT AGCAATTTTT CGCCAAAAGC CAGCACCAGT 60
AAGCTGCCGA CAGATGCATC TCCCGACTCC AAATGCCCCA TCTGCCTGGA TAGATTTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000930--C:gamma-tubulin complex
GO:0016607--C:nuclear speck
GO:0032391--C:photoreceptor connecting cilium
GO:0016605--C:PML body
GO:0000922--C:spindle pole
GO:0000151--C:ubiquitin ligase complex
GO:0003823--F:antigen binding
GO:0003677--F:DNA binding
GO:0019789--F:SUMO transferase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0051457--P:maintenance of protein location in nucleus
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0042127--P:regulation of cell proliferation

KEGG

fab:101814774

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000940	Aegilops tauschii	39.71	1.00e-09	56.60
IUUC-Aml-002240	Ailuropoda melanoleuca	70.12	9.00e-163	567.00
IUUC-Atr-002964	Amborella trichopoda	32.97	4.00e-11	61.20
IUUC-Apl-003666	Anas platyrhynchos	72.07	0.00e+00	652.00
IUUC-Aca-005305	Anolis carolinensis	62.96	2.00e-147	516.00
IUUC-Aly-005926	Arabidopsis lyrata	44.07	1.00e-10	59.70
IUUC-Ath-007299	Arabidopsis thaliana	43.10	3.00e-10	58.50
IUUC-Afu-009120	Aspergillus fumigatus	22.90	6.00e-07	48.10
IUUC-Ame-011109	Astyanax mexicanus	53.99	9.00e-109	387.00
IUUC-Bta-012637	Bos taurus	69.88	1.00e-161	563.00
IUUC-Bdi-014270	Brachypodium distachyon	41.89	6.00e-12	64.30
IUUC-Cja-019105	Callithrix jacchus	69.89	7.00e-171	594.00
IUUC-Cfa-021203	Canis familiaris	70.12	1.00e-162	566.00
IUUC-Cpo-022335	Cavia porcellus	61.63	4.00e-158	552.00
IUUC-Csa-023870	Chlorocebus sabaeus	69.66	1.00e-169	590.00
IUUC-Cho-024870	Choloepus hoffmanni	69.72	7.00e-166	577.00
IUUC-Dre-027535	Danio rerio	53.23	5.00e-114	405.00
IUUC-Dno-028963	Dasypus novemcinctus	70.12	3.00e-159	555.00
IUUC-Dor-030239	Dipodomys ordii	67.01	8.00e-149	520.00
IUUC-Dme-031941	Drosophila melanogaster	30.88	5.00e-36	146.00
IUUC-Ete-032300	Echinops telfairi	67.53	9.00e-151	527.00
IUUC-Eca-033690	Equus caballus	70.56	2.00e-164	573.00
IUUC-Eeu-035257	Erinaceus europaeus	68.62	1.00e-152	533.00
IUUC-Fca-036383	Felis catus	69.81	2.00e-163	569.00
IUUC-Gmo-039416	Gadus morhua	53.00	4.00e-109	387.00
IUUC-Gga-041267	Gallus gallus	80.26	0.00e+00	699.00
IUUC-Gac-042227	Gasterosteus aculeatus	54.98	2.00e-116	412.00
IUUC-Gma-043386	Glycine max	37.04	1.00e-11	63.20
IUUC-Ggo-044445	Gorilla gorilla	69.66	6.00e-170	591.00
IUUC-Hsa-045844	Homo sapiens	63.02	5.00e-170	591.00
IUUC-Itr-048818	Ictidomys tridecemlineatus	67.45	4.00e-161	561.00
IUUC-Lch-050031	Latimeria chalumnae	67.96	2.00e-164	573.00
IUUC-Lpe-051274	Leersia perrieri	38.18	8.00e-09	53.90
IUUC-Loc-052944	Lepisosteus oculatus	63.60	7.00e-128	451.00
IUUC-Laf-053820	Loxodonta africana	71.53	5.00e-164	571.00
IUUC-Mcc-054800	Macaca mulatta	69.66	2.00e-169	589.00
IUUC-Meu-056806	Macropus eugenii	68.37	1.00e-154	539.00
IUUC-Mtr-058378	Medicago truncatula	36.84	5.00e-13	67.80
IUUC-Mvi-060417	Microbotryum violaceum	26.79	5.00e-17	82.80
IUUC-Mmr-061481	Microcebus murinus	71.29	2.00e-165	576.00
IUUC-Mdo-062219	Monodelphis domestica	73.44	8.00e-96	344.00
IUUC-Mmu-064138	Mus musculus	69.88	2.00e-146	513.00
IUUC-Mac-064635	Musa acuminata	40.00	3.00e-12	63.90
IUUC-Mlu-067088	Myotis lucifugus	71.36	7.00e-161	561.00
IUUC-Nle-069862	Nomascus leucogenys	69.66	3.00e-169	588.00
IUUC-Opr-071076	Ochotona princeps	68.00	7.00e-159	554.00
IUUC-Ont-072225	Oreochromis niloticus	53.24	4.00e-104	372.00
IUUC-Oan-073069	Ornithorhynchus anatinus	63.25	3.00e-139	488.00
IUUC-Ocu-074826	Oryctolagus cuniculus	70.42	3.00e-164	572.00
IUUC-Oba-075429	Oryza barthii	40.58	6.00e-11	60.80
IUUC-Obr-076084	Oryza brachyantha	39.13	2.00e-10	59.30
IUUC-Ogl-077444	Oryza glaberrima	40.58	7.00e-11	60.80
IUUC-Ogu-078603	Oryza glumaepatula	40.58	6.00e-11	60.80
IUUC-Oin-079777	Oryza indica	40.58	7.00e-11	60.50
IUUC-Oni-082396	Oryza nivara	40.58	6.00e-11	60.80
IUUC-Opu-083698	Oryza punctata	39.13	4.00e-10	58.20
IUUC-Oru-084305	Oryza rufipogon	40.58	7.00e-11	60.80
IUUC-Ola-087377	Oryzias latipes	55.35	9.00e-106	376.00
IUUC-Oga-088059	Otolemur garnettii	69.84	7.00e-171	594.00
IUUC-Oar-089592	Ovis aries	70.12	6.00e-161	561.00
IUUC-Ptr-091233	Pan troglodytes	69.66	6.00e-170	591.00
IUUC-Pan-092743	Papio anubis	69.66	1.00e-169	590.00
IUUC-Psi-093669	Pelodiscus sinensis	62.41	0.00e+00	853.00
IUUC-Ppa-095668	Physcomitrella patens	24.92	8.00e-19	87.80
IUUC-Pfo-096706	Poecilia formosa	56.87	3.00e-101	362.00
IUUC-Pop-098813	Populus trichocarpa	26.28	1.00e-11	63.50
IUUC-Pca-100967	Procavia capensis	66.59	4.00e-152	531.00
IUUC-Ppe-101922	Prunus persica	37.66	5.00e-09	54.70
IUUC-Pva-102982	Pteropus vampyrus	69.86	2.00e-162	566.00
IUUC-Pgr-103551	Puccinia graminis	38.81	7.00e-08	50.80
IUUC-Ptt-103977	Puccinia triticina	32.05	5.00e-07	47.80
IUUC-Rno-105730	Rattus norvegicus	69.65	7.00e-146	511.00
IUUC-Sha-106588	Sarcophilus harrisii	68.05	5.00e-156	545.00
IUUC-Smo-109417	Selaginella moellendorffii	42.47	1.00e-11	63.90
IUUC-Sly-111835	Solanum lycopersicum	42.37	2.00e-08	54.70
IUUC-Sar-113622	Sorex araneus	67.67	9.00e-108	384.00
IUUC-Sre-115041	Sporisorium reilianum	34.21	4.00e-08	52.00
IUUC-Ssc-115244	Sus scrofa	71.29	2.00e-158	553.00
IUUC-Tgu-117180	Taeniopygia guttata	93.13	0.00e+00	1126.00
IUUC-Tru-118393	Takifugu rubripes	55.14	6.00e-116	411.00
IUUC-Tsy-119408	Tarsius syrichta	69.88	1.00e-162	566.00
IUUC-Tni-120664	Tetraodon nigroviridis	55.08	1.00e-109	390.00
IUUC-Tca-121712	Theobroma cacao	27.46	1.00e-15	76.30
IUUC-Tae-122787	Triticum aestivum	41.43	6.00e-11	61.20
IUUC-Tbe-127301	Tupaia belangeri	70.26	8.00e-148	517.00
IUUC-Ttr-128204	Tursiops truncatus	70.82	4.00e-164	572.00
IUUC-Uma-129420	Ustilago maydis	41.10	2.00e-09	55.80
IUUC-Vpa-130297	Vicugna pacos	70.73	5.00e-163	568.00
IUUC-Vvi-131157	Vitis vinifera	40.00	1.00e-09	57.40
IUUC-Xtr-132845	Xenopus tropicalis	66.20	1.00e-167	583.00
IUUC-Xma-133439	Xiphophorus maculatus	55.71	2.00e-101	363.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence