iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106588

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01074981

Gene Name

TOPORS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000009919.1	ENSSHAT00000011639.1	ENSSHAP00000011543.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.10e-08	33.8	61	100

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl+ f++  +++ C H f++ C+q w      s++++ CPlC+
   Q: 61   CPICLDKFDNVAYLGHCLHKFCFRCVQEW------SKNKAECPLCK 100
           **********888899*************......**********7 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

PSVLGRKSTC SNRKYTDVSF SFQVMASAAE EFTVDNNFSP KAGTSKLQWT VPADASPDSK 60
CPICLDKFDN VAYLGHCLHK FCFRCVQEWS KNKAECPLCK QPFQSIFHSV RAENDFEEYV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTTCAGTAT TGGGTAGAAA ATCTACTTGC AGTAACAGAA AAGTAAACTG TGGAGGGAAA 60
TTAGTCTTTT TTTTTTTTTT CCAAGAGAAA AAAATTTTCT GGCATTTTCT AATTTTCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000930--C:gamma-tubulin complex
GO:0016607--C:nuclear speck
GO:0032391--C:photoreceptor connecting cilium
GO:0016605--C:PML body
GO:0000922--C:spindle pole
GO:0000151--C:ubiquitin ligase complex
GO:0003823--F:antigen binding
GO:0003677--F:DNA binding
GO:0019789--F:SUMO transferase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0051457--P:maintenance of protein location in nucleus
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0042127--P:regulation of cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000940	Aegilops tauschii	36.76	1.00e-08	53.50
IUUC-Aml-002240	Ailuropoda melanoleuca	69.53	0.00e+00	677.00
IUUC-Atr-002964	Amborella trichopoda	25.14	1.00e-08	53.50
IUUC-Apl-003666	Anas platyrhynchos	65.08	5.00e-148	518.00
IUUC-Aca-005305	Anolis carolinensis	62.41	3.00e-148	519.00
IUUC-Aly-005926	Arabidopsis lyrata	37.35	9.00e-10	57.00
IUUC-Ath-007299	Arabidopsis thaliana	42.37	1.00e-09	56.60
IUUC-Ame-011109	Astyanax mexicanus	52.39	3.00e-109	389.00
IUUC-Bta-012637	Bos taurus	71.56	0.00e+00	682.00
IUUC-Bdi-014270	Brachypodium distachyon	40.00	7.00e-11	60.80
IUUC-Bol-015147	Brassica oleracea	42.42	1.00e-08	55.10
IUUC-Cja-019105	Callithrix jacchus	70.13	0.00e+00	686.00
IUUC-Cfa-021203	Canis familiaris	71.40	0.00e+00	676.00
IUUC-Cpo-022335	Cavia porcellus	67.23	0.00e+00	637.00
IUUC-Csa-023870	Chlorocebus sabaeus	70.20	0.00e+00	684.00
IUUC-Cho-024870	Choloepus hoffmanni	77.31	5.00e-180	624.00
IUUC-Cne-026788	Cryptococcus neoformans	35.59	2.00e-07	51.20
IUUC-Dre-027535	Danio rerio	50.58	5.00e-112	399.00
IUUC-Dno-028963	Dasypus novemcinctus	72.17	0.00e+00	658.00
IUUC-Dor-030239	Dipodomys ordii	69.87	1.00e-175	610.00
IUUC-Dme-031941	Drosophila melanogaster	34.45	3.00e-18	87.80
IUUC-Ete-032300	Echinops telfairi	61.41	0.00e+00	757.00
IUUC-Eca-033690	Equus caballus	72.62	0.00e+00	671.00
IUUC-Eeu-035257	Erinaceus europaeus	72.59	0.00e+00	662.00
IUUC-Fca-036383	Felis catus	70.84	0.00e+00	671.00
IUUC-Fal-037209	Ficedula albicollis	68.28	5.00e-157	548.00
IUUC-Gmo-039416	Gadus morhua	50.00	5.00e-110	390.00
IUUC-Gga-041267	Gallus gallus	71.49	8.00e-173	601.00
IUUC-Gac-042227	Gasterosteus aculeatus	52.10	1.00e-110	392.00
IUUC-Gma-043193	Glycine max	41.79	2.00e-09	57.40
IUUC-Ggo-044445	Gorilla gorilla	70.63	0.00e+00	679.00
IUUC-Hsa-045844	Homo sapiens	70.82	0.00e+00	680.00
IUUC-Itr-048818	Ictidomys tridecemlineatus	69.72	0.00e+00	668.00
IUUC-Lch-050031	Latimeria chalumnae	62.20	5.00e-161	561.00
IUUC-Lpe-051274	Leersia perrieri	37.74	3.00e-08	51.60
IUUC-Loc-052944	Lepisosteus oculatus	60.18	2.00e-134	473.00
IUUC-Lma-053202	Leptosphaeria maculans	24.61	1.00e-09	56.20
IUUC-Laf-053820	Loxodonta africana	71.98	0.00e+00	656.00
IUUC-Mcc-054800	Macaca mulatta	70.20	0.00e+00	685.00
IUUC-Meu-056806	Macropus eugenii	91.99	0.00e+00	814.00
IUUC-Mtr-058378	Medicago truncatula	43.66	2.00e-11	62.40
IUUC-Mla-059017	Melampsora laricipopulina	36.07	5.00e-09	55.50
IUUC-Mvi-060417	Microbotryum violaceum	24.04	1.00e-17	84.70
IUUC-Mmr-061481	Microcebus murinus	71.32	0.00e+00	677.00
IUUC-Mdo-062219	Monodelphis domestica	86.15	0.00e+00	908.00
IUUC-Mmu-064138	Mus musculus	70.50	5.00e-175	608.00
IUUC-Mlu-067088	Myotis lucifugus	70.52	0.00e+00	667.00
IUUC-Nle-069862	Nomascus leucogenys	70.39	0.00e+00	684.00
IUUC-Opr-071076	Ochotona princeps	72.67	0.00e+00	639.00
IUUC-Ont-072225	Oreochromis niloticus	48.87	8.00e-104	371.00
IUUC-Oan-073069	Ornithorhynchus anatinus	66.28	6.00e-155	540.00
IUUC-Ocu-074826	Oryctolagus cuniculus	74.40	0.00e+00	677.00
IUUC-Obr-076084	Oryza brachyantha	36.23	2.00e-09	56.20
IUUC-Ogl-077444	Oryza glaberrima	37.68	7.00e-10	57.80
IUUC-Ogu-078603	Oryza glumaepatula	37.68	6.00e-10	57.80
IUUC-Oin-079777	Oryza indica	37.68	7.00e-10	57.40
IUUC-Oni-082396	Oryza nivara	37.68	6.00e-10	57.80
IUUC-Opu-083698	Oryza punctata	36.62	3.00e-09	55.50
IUUC-Oru-084305	Oryza rufipogon	37.68	4.00e-10	58.50
IUUC-Ola-087377	Oryzias latipes	52.24	1.00e-104	373.00
IUUC-Oga-088059	Otolemur garnettii	70.61	0.00e+00	673.00
IUUC-Oar-089592	Ovis aries	73.69	0.00e+00	680.00
IUUC-Ptr-091233	Pan troglodytes	70.63	0.00e+00	679.00
IUUC-Pan-092743	Papio anubis	70.20	0.00e+00	685.00
IUUC-Psi-093669	Pelodiscus sinensis	59.48	0.00e+00	874.00
IUUC-Ppa-095668	Physcomitrella patens	28.71	2.00e-25	110.00
IUUC-Pfo-096706	Poecilia formosa	53.41	6.00e-104	371.00
IUUC-Pop-099591	Populus trichocarpa	45.45	3.00e-09	57.00
IUUC-Pca-100967	Procavia capensis	68.46	3.00e-172	598.00
IUUC-Ppe-101922	Prunus persica	34.72	2.00e-08	52.40
IUUC-Pva-102982	Pteropus vampyrus	71.27	0.00e+00	679.00
IUUC-Pgr-103551	Puccinia graminis	38.46	2.00e-08	52.40
IUUC-Ptt-103977	Puccinia triticina	30.95	3.00e-07	48.90
IUUC-Rno-105730	Rattus norvegicus	69.96	1.00e-170	593.00
IUUC-Sja-107735	Schizosaccharomyces japonicus	35.38	4.00e-07	48.50
IUUC-Smo-109039	Selaginella moellendorffii	24.10	2.00e-18	86.70
IUUC-Sly-111835	Solanum lycopersicum	43.33	5.00e-09	56.60
IUUC-Stu-112898	Solanum tuberosum	43.33	5.00e-09	56.60
IUUC-Sar-113622	Sorex araneus	77.63	1.00e-120	427.00
IUUC-Sre-115041	Sporisorium reilianum	35.14	2.00e-08	52.80
IUUC-Ssc-115244	Sus scrofa	71.32	0.00e+00	631.00
IUUC-Tgu-117180	Taeniopygia guttata	68.93	3.00e-161	562.00
IUUC-Tru-118393	Takifugu rubripes	50.70	1.00e-113	403.00
IUUC-Tsy-119408	Tarsius syrichta	71.06	0.00e+00	663.00
IUUC-Tni-120664	Tetraodon nigroviridis	53.46	6.00e-114	404.00
IUUC-Tca-121712	Theobroma cacao	26.75	4.00e-17	82.00
IUUC-Tae-122787	Triticum aestivum	38.57	5.00e-10	58.20
IUUC-Tur-126349	Triticum urartu	41.67	8.00e-09	56.20
IUUC-Tbe-127301	Tupaia belangeri	70.97	7.00e-172	597.00
IUUC-Ttr-128204	Tursiops truncatus	71.88	0.00e+00	689.00
IUUC-Uma-129420	Ustilago maydis	43.06	1.00e-09	57.40
IUUC-Vpa-130297	Vicugna pacos	74.46	0.00e+00	685.00
IUUC-Vvi-131157	Vitis vinifera	25.17	2.00e-16	80.10
IUUC-Xtr-132845	Xenopus tropicalis	64.71	1.00e-167	583.00
IUUC-Xma-133439	Xiphophorus maculatus	53.53	2.00e-108	386.00
IUUC-Yli-134652	Yarrowia lipolytica	36.73	2.00e-06	47.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence