iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062253

UUCD1 version

UUC-MoD-01151

Ensembl Protein ID

ENSMODP00000026010.2

UniProt Accession

F6S7P0; F6S7P0_MONDO

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000020795.2	ENSMODT00000026475.2	ENSMODP00000026010.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-62	211.5	409	785

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw......kskkk.............avspr 71
           Gl N g  CY+N++LQ+L+++p++ +l++   +   ++ +++ +++++++s+ +l++ l+      k k+              a++p+
   Q: 409  GLINKGHWCYINATLQALVACPPMYHLMKF-IPV-YSKVQRPCTSTPMIDSFVRLMNGLTnmpippKAKQAlgdkivrdispgaAFEPT 495
           9**************************999.333.333445799***************7776664333337788888888888***** PP
   S: 72   ellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsde............. 129
            +++ l  +++ +s + +q+Da+E+ +f+l++l+ee+ +                             d                    
   Q: 496  YIYRLLTVIKSGLSeKGRQEDAEEYPEFILNGLHEEMLNlkkllipnnenfsvsngP-----------D------Aqsvhedeqghgeg 567
           *9999999999865599********************44454666443333322221...........2......13333445677777 PP
   S: 130  ..............aeekkkkknk...slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeele 201
                         +  ++    +   ++i+ +F+g+l+ +++ +e  ++s + +pf++l+l++++++     +++d+Les +++e+++
   Q: 568  sedkweqvgprnktSVTRQA---DfikTPITGIFGGHLR-SVVYQESSKESATLQPFFTLQLDIQSDKIH---TVRDALESLVARESVQ 649
           77767777666444444444...2555***********9.6889999*********************88...**************** PP
   S: 202  genkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke..kkkYeLiavvvHsG 288
           g    y+ k ++++e +++++l+klP+ L+lhLkRf +++++ + +k+ k++e+p  L++s+ + sp  k+k+   ++Y L+av++H+G
   Q: 650  G----YTIKTNQEVEISRRVTLEKLPPLLVLHLKRFVYEKTGRC-QKLIKNIEYPVDLEISRELLSPVVKNKNfkGRNYHLFAVIYHHG 733
           8....8889999*************************9888666.5***************9888866555555599************ PP
   S: 289  .slssGHYvayvknekgk.WllfdDskVtevkeeevleetg.staYvlfYkr 337
            s+ +GHY+a+v + + + Wl++dD+ V+++++ +v++ ++ +taY+l+Y+r
   Q: 734  nSAPGGHYTADVFQIDLNgWLHIDDQAVKVINQYQVVKPSAeRTAYLLYYRR 785
           **************88888*****************998778********98 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MARHGPQCVS GDFTPDEFNQ FLVTPCSSIE LPPYNKQFCM RGSTVDRQLI GEEYQRIEFG 60
VTEVIEQDES LDYSHSSTLN PQAPKFILGC TTSKKNHDDI HNATNYNSID YPFTSPVLAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCCGCC ACGGCCCCCA GTGTGTTTCT GGAGATTTTA CTCCTGATGA GTTCAATCAG 60
TTTTTGGTGA CTCCTTGTTC TTCTATCGAG CTTCCGCCAT ATAATTAAAC AATTTTGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005769--C:early endosome
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bdi-015039	Brachypodium distachyon	33.50	3.00e-52	199.00
IUUC-Ola-086931	Oryzias latipes	51.94	0.00e+00	695.00
IUUC-Sce-106160	Saccharomyces cerevisiae	26.11	9.00e-40	159.00
IUUC-Sit-110781	Setaria italica	31.90	9.00e-56	211.00
IUUC-Tru-117542	Takifugu rubripes	54.20	0.00e+00	747.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence