iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026231

UUCD1 version

UUC-CiS-00444

Ensembl Protein ID

ENSCSAVP00000004860.1

UniProt Accession

H2YHR1; H2YHR1_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000002893.1	ENSCSAVT00000004928.1	ENSCSAVP00000004860.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	5.80e-88	295.9	45	234

Active Site

Position(s)	Description	Evidence
215	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 17   ksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleeei 104
           +s++ l++GagglGcEllK L l+G+++i+v+Dmdt+++snlnrqFLfr +d+gk KAevaa +++++++  +  +h ++i++ + + 
   Q: 45   ESCRLLVIGAGGLGCELLKDLSLMGFRQIHVIDMDTIDLSNLNRQFLFRHSDIGKAKAEVAASFINKRVRGTKCIPHFCKIQDYDSS- 131
           5799********************************************************************************999. PP
   S: 105  vFfkkfdvVvlaldnrearrkvnrlclna.............rvpliesgtlGllGqvrviikgltecyscsd..dppqktiPfctlk 177
            F+k+f+++v++ld++ arr++n +++++              +pl+++gt+G++G++rvi++g+t+c +c+   +ppq+++P+ct++
   Q: 132  -FYKQFHIIVCGLDSIVARRWMNGMLISLleydddgnldpssIIPLVDGGTEGFKGNARVILPGMTACMDCTLdlYPPQVNFPMCTIA 218
           .************************************************************************9************** PP
   S: 178  etpnaaehtiewavlf 193
           +tp+++eh+ie++ lf
   Q: 219  HTPRQPEHCIEYIKLF 234
           *************444 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

MEVDEVVGTK WTGRWKHLRK ILERSSPFAH PDFEPSPDIL EFMQESCRLL VIGAGGLGCE 60
LLKDLSLMGF RQIHVIDMDT IDLSNLNRQF LFRHSDIGKA KAEVAASFIN KRVRGTKCIP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAAGTCG ACGAGGTAGT GGGTACTAAA TGGACAGGGC GGTGGAAACA TTTGCGTAAA 60
ATCTTGGAGA GGAGCAGTCC ATTTGCACAC CCTGATTTCG AACCAAGTCC AGATGTAAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014929--E2_binding
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR030468--Uba3
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF08825--E2_bind
PF00899--ThiF

SMART

SM01181--E2_bind

Gene Ontology

GO:0016881--F:acid-amino acid ligase activity
GO:0005524--F:ATP binding
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001124	Aegilops tauschii	48.37	2.00e-81	294.00
IUUC-Aml-001578	Ailuropoda melanoleuca	68.14	0.00e+00	647.00
IUUC-Atr-002591	Amborella trichopoda	48.88	3.00e-92	330.00
IUUC-Apl-003671	Anas platyrhynchos	65.76	0.00e+00	634.00
IUUC-Aca-004749	Anolis carolinensis	66.04	0.00e+00	626.00
IUUC-Aly-005747	Arabidopsis lyrata	47.77	1.00e-99	354.00
IUUC-Ath-006623	Arabidopsis thaliana	48.27	6.00e-100	355.00
IUUC-Ago-007934	Ashbya gossypii	41.99	4.00e-68	249.00
IUUC-Acl-008047	Aspergillus clavatus	50.00	6.00e-121	425.00
IUUC-Afl-008615	Aspergillus flavus	43.00	7.00e-75	272.00
IUUC-Afu-008996	Aspergillus fumigatus	48.94	3.00e-114	403.00
IUUC-Ani-009281	Aspergillus nidulans	42.55	7.00e-83	298.00
IUUC-Ang-009539	Aspergillus niger	49.88	2.00e-109	387.00
IUUC-Aor-010151	Aspergillus oryzae	48.02	3.00e-105	373.00
IUUC-Ate-010502	Aspergillus terreus	50.97	4.00e-111	392.00
IUUC-Ame-011837	Astyanax mexicanus	66.14	2.00e-177	613.00
IUUC-Bgr-012068	Blumeria graminis	50.79	3.00e-105	374.00
IUUC-Bta-013003	Bos taurus	68.37	0.00e+00	650.00
IUUC-Bci-013983	Botrytis cinerea	49.20	9.00e-117	411.00
IUUC-Bdi-014429	Brachypodium distachyon	47.23	7.00e-90	322.00
IUUC-Bol-015490	Brassica oleracea	48.38	3.00e-90	323.00
IUUC-Bra-018023	Brassica rapa	47.88	7.00e-89	319.00
IUUC-Cel-018684	Caenorhabditis elegans	51.75	2.00e-130	457.00
IUUC-Cja-019200	Callithrix jacchus	67.34	0.00e+00	642.00
IUUC-Cfa-021038	Canis familiaris	68.37	0.00e+00	649.00
IUUC-Cpo-021842	Cavia porcellus	37.64	2.00e-30	125.00
IUUC-Cre-022778	Chlamydomonas reinhardtii	47.79	3.00e-107	380.00
IUUC-Csa-024079	Chlorocebus sabaeus	68.14	0.00e+00	650.00
IUUC-Cho-025052	Choloepus hoffmanni	60.47	3.00e-163	566.00
IUUC-Cin-025113	Ciona intestinalis	84.01	0.00e+00	769.00
IUUC-Cgl-026535	Colletotrichum gloeosporioides	50.23	4.00e-123	433.00
IUUC-Cne-026850	Cryptococcus neoformans	46.12	7.00e-104	369.00
IUUC-Cme-027275	Cyanidioschyzon merolae	35.68	2.00e-67	248.00
IUUC-Dre-028751	Danio rerio	66.59	4.00e-178	615.00
IUUC-Dno-029571	Dasypus novemcinctus	67.91	0.00e+00	645.00
IUUC-Dor-030395	Dipodomys ordii	67.69	5.00e-180	622.00
IUUC-Dse-031329	Dothistroma septosporum	43.40	4.00e-97	346.00
IUUC-Dme-031776	Drosophila melanogaster	61.25	9.00e-156	541.00
IUUC-Ete-032894	Echinops telfairi	58.24	5.00e-52	197.00
IUUC-Eca-034389	Equus caballus	68.37	0.00e+00	650.00
IUUC-Eeu-035152	Erinaceus europaeus	60.60	4.00e-144	503.00
IUUC-Fca-036032	Felis catus	68.37	0.00e+00	650.00
IUUC-Fal-037506	Ficedula albicollis	64.71	0.00e+00	628.00
IUUC-Fox-037871	Fusarium oxysporum	51.61	1.00e-107	380.00
IUUC-Fso-038350	Fusarium solani	50.47	2.00e-118	417.00
IUUC-Gmo-039246	Gadus morhua	68.07	6.00e-178	615.00
IUUC-Ggr-039859	Gaeumannomyces graminis	50.24	8.00e-113	398.00
IUUC-Gga-040843	Gallus gallus	63.35	5.00e-174	602.00
IUUC-Gac-042610	Gasterosteus aculeatus	68.54	1.00e-176	610.00
IUUC-Gma-042744	Glycine max	49.35	2.00e-93	333.00
IUUC-Ggo-044788	Gorilla gorilla	68.45	0.00e+00	647.00
IUUC-Hsa-045849	Homo sapiens	68.60	0.00e+00	651.00
IUUC-Hvu-047819	Hordeum vulgare	51.81	2.00e-85	307.00
IUUC-Itr-047863	Ictidomys tridecemlineatus	67.67	0.00e+00	645.00
IUUC-Kpa-049393	Komagataella pastoris	50.76	2.00e-94	337.00
IUUC-Lch-049471	Latimeria chalumnae	66.51	5.00e-177	612.00
IUUC-Lpe-051297	Leersia perrieri	47.88	3.00e-98	350.00
IUUC-Loc-052910	Lepisosteus oculatus	65.84	6.00e-176	608.00
IUUC-Lma-053181	Leptosphaeria maculans	48.74	9.00e-118	415.00
IUUC-Laf-054314	Loxodonta africana	67.13	0.00e+00	641.00
IUUC-Mcc-054870	Macaca mulatta	68.60	0.00e+00	651.00
IUUC-Meu-056574	Macropus eugenii	56.07	2.00e-92	331.00
IUUC-Mor-056919	Magnaporthe oryzae	50.96	1.00e-117	414.00
IUUC-Mpo-057614	Magnaporthe poae	50.00	2.00e-106	377.00
IUUC-Mtr-058110	Medicago truncatula	49.35	5.00e-92	329.00
IUUC-Mla-058949	Melampsora laricipopulina	49.51	2.00e-110	390.00
IUUC-Mga-059455	Meleagris gallopavo	65.16	0.00e+00	630.00
IUUC-Mvi-060270	Microbotryum violaceum	47.58	1.00e-108	384.00
IUUC-Mmr-061155	Microcebus murinus	67.59	0.00e+00	627.00
IUUC-Mdo-062037	Monodelphis domestica	68.15	0.00e+00	641.00
IUUC-Mmu-063670	Mus musculus	68.60	0.00e+00	652.00
IUUC-Mac-064711	Musa acuminata	47.96	4.00e-92	330.00
IUUC-Mpu-066734	Mustela putorius furo	68.06	0.00e+00	648.00
IUUC-Mlu-067068	Myotis lucifugus	68.38	0.00e+00	643.00
IUUC-Nfi-068349	Neosartorya fischeri	48.94	7.00e-114	402.00
IUUC-Ncr-068626	Neurospora crassa	49.03	2.00e-105	374.00
IUUC-Nle-069366	Nomascus leucogenys	62.78	2.00e-167	580.00
IUUC-Opr-070993	Ochotona princeps	70.54	7.00e-51	192.00
IUUC-Ont-072196	Oreochromis niloticus	67.59	7.00e-178	615.00
IUUC-Oan-073511	Ornithorhynchus anatinus	67.21	0.00e+00	641.00
IUUC-Ocu-073773	Oryctolagus cuniculus	68.84	0.00e+00	651.00
IUUC-Oba-075726	Oryza barthii	44.89	4.00e-90	323.00
IUUC-Obr-076286	Oryza brachyantha	47.88	1.00e-96	345.00
IUUC-Ogl-077686	Oryza glaberrima	39.34	1.00e-39	156.00
IUUC-Ogu-078473	Oryza glumaepatula	44.89	3.00e-90	323.00
IUUC-Oin-079393	Oryza indica	49.13	1.00e-101	361.00
IUUC-Olo-080446	Oryza longistaminata	47.13	1.00e-93	335.00
IUUC-Ome-081737	Oryza meridionalis	47.13	9.00e-94	335.00
IUUC-Oni-082853	Oryza nivara	44.89	4.00e-90	323.00
IUUC-Opu-083590	Oryza punctata	48.88	7.00e-101	358.00
IUUC-Oru-084184	Oryza rufipogon	44.89	4.00e-90	323.00
IUUC-Osa-085402	Oryza sativa	49.13	1.00e-101	361.00
IUUC-Ola-086615	Oryzias latipes	63.13	1.00e-163	567.00
IUUC-Olu-087738	Ostreococcus lucimarinus	44.96	2.00e-90	324.00
IUUC-Oga-088101	Otolemur garnettii	68.14	0.00e+00	649.00
IUUC-Oar-090293	Ovis aries	67.59	0.00e+00	642.00
IUUC-Ptr-090503	Pan troglodytes	68.60	0.00e+00	651.00
IUUC-Pan-092477	Papio anubis	66.74	0.00e+00	626.00
IUUC-Psi-093442	Pelodiscus sinensis	66.98	0.00e+00	639.00
IUUC-Pma-094247	Petromyzon marinus	65.97	1.00e-172	597.00
IUUC-Pno-094780	Phaeosphaeria nodorum	46.30	1.00e-110	391.00
IUUC-Ppa-095961	Physcomitrella patens	48.92	7.00e-118	415.00
IUUC-Pfo-097137	Poecilia formosa	66.67	8.00e-179	618.00
IUUC-Pab-098060	Pongo abelii	68.60	1.00e-178	617.00
IUUC-Pop-099470	Populus trichocarpa	48.96	2.00e-97	347.00
IUUC-Pca-100500	Procavia capensis	55.35	2.00e-142	496.00
IUUC-Ppe-102008	Prunus persica	48.44	4.00e-88	316.00
IUUC-Pva-103095	Pteropus vampyrus	71.56	3.00e-92	330.00
IUUC-Pgr-103666	Puccinia graminis	47.43	2.00e-111	394.00
IUUC-Ptt-103901	Puccinia triticina	48.27	3.00e-116	410.00
IUUC-Pte-104198	Pyrenophora teres	48.38	2.00e-116	410.00
IUUC-Pyt-104792	Pyrenophora triticirepentis	48.61	6.00e-114	402.00
IUUC-Rno-105446	Rattus norvegicus	68.60	0.00e+00	652.00
IUUC-Sce-106355	Saccharomyces cerevisiae	40.58	1.00e-64	238.00
IUUC-Sha-106664	Sarcophilus harrisii	67.92	0.00e+00	640.00
IUUC-Sja-107982	Schizosaccharomyces japonicus	40.89	1.00e-90	325.00
IUUC-Spo-108345	Schizosaccharomyces pombe	42.17	1.00e-93	335.00
IUUC-Ssl-108540	Sclerotinia sclerotiorum	47.09	4.00e-104	370.00
IUUC-Smo-109098	Selaginella moellendorffii	47.73	9.00e-115	405.00
IUUC-Sit-109724	Setaria italica	48.51	2.00e-93	334.00
IUUC-Sly-110916	Solanum lycopersicum	48.70	9.00e-96	342.00
IUUC-Stu-112236	Solanum tuberosum	48.70	2.00e-95	341.00
IUUC-Sar-113044	Sorex araneus	68.33	1.00e-174	604.00
IUUC-Sbi-114276	Sorghum bicolor	48.88	7.00e-94	335.00
IUUC-Sre-114963	Sporisorium reilianum	48.23	3.00e-112	396.00
IUUC-Ssc-116301	Sus scrofa	67.82	0.00e+00	645.00
IUUC-Tgu-117265	Taeniopygia guttata	64.93	0.00e+00	629.00
IUUC-Tru-117526	Takifugu rubripes	66.05	3.00e-175	606.00
IUUC-Tsy-119483	Tarsius syrichta	68.12	4.00e-180	622.00
IUUC-Tni-120363	Tetraodon nigroviridis	67.29	2.00e-176	610.00
IUUC-Tca-121731	Theobroma cacao	48.13	2.00e-91	327.00
IUUC-Tre-122221	Trichoderma reesei	50.13	2.00e-105	374.00
IUUC-Tvi-122352	Trichoderma virens	48.51	4.00e-120	422.00
IUUC-Tae-123864	Triticum aestivum	48.63	7.00e-92	329.00
IUUC-Tur-126070	Triticum urartu	46.27	4.00e-72	263.00
IUUC-Tme-127199	Tuber melanosporum	49.35	2.00e-101	360.00
IUUC-Tbe-128076	Tupaia belangeri	67.91	0.00e+00	649.00
IUUC-Ttr-128695	Tursiops truncatus	55.41	3.00e-78	284.00
IUUC-Uma-129638	Ustilago maydis	47.99	2.00e-112	397.00
IUUC-Vda-129963	Verticillium dahliae	48.96	3.00e-111	393.00
IUUC-Vpa-130637	Vicugna pacos	61.16	5.00e-163	565.00
IUUC-Vvi-131613	Vitis vinifera	46.62	2.00e-86	310.00
IUUC-Xtr-132924	Xenopus tropicalis	65.20	6.00e-171	592.00
IUUC-Xma-133356	Xiphophorus maculatus	66.90	4.00e-178	615.00
IUUC-Yli-134365	Yarrowia lipolytica	51.80	2.00e-108	384.00
IUUC-Zma-135941	Zea mays	44.22	3.00e-87	313.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence