iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053782

Ensembl Protein ID

ENSLAFP00000028162.1

UniProt Accession

G3UK03; G3UK03_LOXAF

Protein Name

Uncharacterized protein

Gene Name

TNK2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000005804.3	ENSLAFT00000005805.3	ENSLAFP00000004866.3
ENSLAFG00000005804.3	ENSLAFT00000025706.1	ENSLAFP00000028845.1
ENSLAFG00000005804.3	ENSLAFT00000032421.1	ENSLAFP00000028162.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	90.70	0.00e+00	1640.00	IUUC-Hsa-046670
UBD/Alpha-Helix/UBA	91.65	0.00e+00	1688.00	IUUC-Mmu-063861

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MQPEEGTGWL LELLSEVQLQ QYFLRLRDDL NVTRLSHFEY VKNEDLEKIG MGRPGQRRLW 60
EAVKRRKAXX XPRAAFKQVF SGKRLETEFP PDHSQSAFRK TSPTPGGPAG EGPLQSLTCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAGGCTGG GGAGCAGCAG CATGCAGCCG GAGGAGGGCA CGGGCTGGCT GCTGGAGCTG 60
CTGTCGGAGG TGCAGCTACA ACAGTACTTC CTGCGGCTCC GCGACGACCT CAACGTCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR015116--Cdc42_binding_dom-like
IPR011009--Kinase-like_dom
IPR021619--Mig-6
IPR000719--Prot_kinase_dom
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50002--SH3

Pfam

PF09027--GTPase_binding
PF11555--Inhibitor_Mig-6
PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00109--TYRKINASE

SMART

SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030136--C:clathrin-coated vesicle
GO:0070436--C:Grb2-EGFR complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0004713--F:protein tyrosine kinase activity
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:2000369--P:regulation of clathrin-dependent endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002166	Ailuropoda melanoleuca	90.35	0.00e+00	1625.00
IUUC-Aca-004315	Anolis carolinensis	87.50	1.00e-71	261.00
IUUC-Ame-011350	Astyanax mexicanus	53.45	0.00e+00	999.00
IUUC-Bta-012325	Bos taurus	91.37	0.00e+00	1680.00
IUUC-Cel-018130	Caenorhabditis elegans	35.42	3.00e-82	300.00
IUUC-Cja-019545	Callithrix jacchus	85.57	0.00e+00	1534.00
IUUC-Cfa-020706	Canis familiaris	91.00	0.00e+00	1693.00
IUUC-Cpo-022032	Cavia porcellus	87.00	0.00e+00	1618.00
IUUC-Csa-023936	Chlorocebus sabaeus	92.41	0.00e+00	1672.00
IUUC-Csv-026328	Ciona savignyi	57.23	8.00e-165	573.00
IUUC-Dre-028714	Danio rerio	62.24	0.00e+00	1171.00
IUUC-Dno-029525	Dasypus novemcinctus	91.18	0.00e+00	1683.00
IUUC-Dme-031778	Drosophila melanogaster	53.45	1.00e-135	477.00
IUUC-Ete-032225	Echinops telfairi	86.06	0.00e+00	806.00
IUUC-Fca-035664	Felis catus	91.86	0.00e+00	1751.00
IUUC-Gmo-039543	Gadus morhua	56.96	0.00e+00	889.00
IUUC-Gga-040241	Gallus gallus	68.12	0.00e+00	1276.00
IUUC-Gac-041457	Gasterosteus aculeatus	60.50	0.00e+00	1070.00
IUUC-Ggo-045333	Gorilla gorilla	90.13	0.00e+00	1644.00
IUUC-Hsa-046670	Homo sapiens	90.70	0.00e+00	1611.00
IUUC-Itr-048054	Ictidomys tridecemlineatus	92.41	0.00e+00	1721.00
IUUC-Lch-049670	Latimeria chalumnae	62.15	0.00e+00	1164.00
IUUC-Loc-052870	Lepisosteus oculatus	62.74	0.00e+00	1222.00
IUUC-Mcc-055874	Macaca mulatta	92.60	0.00e+00	1667.00
IUUC-Mga-059717	Meleagris gallopavo	69.70	0.00e+00	1320.00
IUUC-Mdo-062270	Monodelphis domestica	84.96	0.00e+00	1568.00
IUUC-Mmu-063861	Mus musculus	91.65	0.00e+00	1736.00
IUUC-Mpu-066127	Mustela putorius furo	93.32	0.00e+00	1321.00
IUUC-Mlu-067937	Myotis lucifugus	89.20	0.00e+00	1297.00
IUUC-Nle-069298	Nomascus leucogenys	91.02	0.00e+00	1379.00
IUUC-Ont-072437	Oreochromis niloticus	57.41	0.00e+00	1141.00
IUUC-Oan-073708	Ornithorhynchus anatinus	75.00	4.00e-117	415.00
IUUC-Ola-087023	Oryzias latipes	60.51	0.00e+00	1086.00
IUUC-Pan-091857	Papio anubis	93.36	2.00e-96	344.00
IUUC-Psi-093401	Pelodiscus sinensis	52.62	1.00e-140	493.00
IUUC-Pfo-097455	Poecilia formosa	58.30	0.00e+00	1144.00
IUUC-Rno-105586	Rattus norvegicus	91.27	0.00e+00	1713.00
IUUC-Sha-106868	Sarcophilus harrisii	80.81	0.00e+00	1529.00
IUUC-Ssc-116250	Sus scrofa	90.90	0.00e+00	1632.00
IUUC-Tgu-116592	Taeniopygia guttata	68.53	0.00e+00	1262.00
IUUC-Tru-117852	Takifugu rubripes	66.88	3.00e-165	576.00
IUUC-Tsy-119087	Tarsius syrichta	98.50	9.00e-157	547.00
IUUC-Tni-120826	Tetraodon nigroviridis	61.28	0.00e+00	1172.00
IUUC-Xtr-132069	Xenopus tropicalis	63.23	0.00e+00	1105.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence