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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-064057
Ensembl Protein ID ENSMUSP00000039757.6
UniProt Accession O88379; Q3TKK7; Q3UXF6; BAZ1A_MOUSE
Genbank Protein ID BAE22607.1; BAE39138.1; AAC32043.1
Protein Name Bromodomain adjacent to zinc finger domain protein 1A; Cbp146
Genbank Nucleotide ID AC138767; AK166955; AF033664
Gene Name Baz1a; Cbp146
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000035021.13 ENSMUST00000173433.7 ENSMUSP00000133478.1
ENSMUSG00000035021.13 ENSMUST00000174225.1 ENSMUSP00000133324.1
ENSMUSG00000035021.13 ENSMUST00000173176.1 ENSMUSP00000134207.1
ENSMUSG00000035021.13 ENSMUST00000038926.12 ENSMUSP00000039757.6
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRAID2
Protein-protein Interaction
IIDPINAHINT
Drug and target
GRAC
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMUniProt
PHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 1.00e-08 36.3 1150 1198
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           + C++C+++g+ e ++v C+ C++  H  C+ ++  + +p+ + w+Cp+Cr 
   Q: 1150 ARCKICRKKGDAE-NMVLCDGCDRGHHTYCVRPK-LKAVPDGD-WFCPECRP 1198
           57*********98.6*******************.*******7.******96 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Component of the histone-fold protein complex CHRAC complex which faciliates nucleosome sliding by the ACF complex and enhances ACF-mediated chromatin assembly. The C-terminal regions of both CHRAC1 and POLE1 are required for these functions (By similarity).
 Component of the histone-fold protein complex CHRAC complex which faciliates nucleosome sliding by the ACF complex and enhances ACF-mediated chromatin assembly. The C-terminal regions of both CHRAC1 and POLE1 are required for these functions (By similarity).
Protein Sequence
(Fasta)
MPLLHRKPFV RQKPPGDLRP DEEVFYCKVT NEIFRHYDDF FERTILCNSL VWSCAVTGRP 60
GLTYQEALES ERKARQNLQS FPEPLIIPVL YLTNLTRRSR LHEICDDIFA YVKDRYFVEE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064057|E3,PHD|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCCATTTGAC AGTCAGCCTG TAGCTTTCCA ACGCCAAAGC AAAGGTAATT ACTGAAGTAT 60
TTCTTAGCGG TTTCGAGCGT TTGTTTTCTG GAATTGCACA TAGCATATAA GATCTGCCAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064057|E3,PHD|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR018501--DDT_dom
IPR028942--WHIM1_dom
IPR028941--WHIM2_dom
IPR013136--WSTF_Acf1_Cbp146
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS50827--DDT
PS51136--WAC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF00439--Bromodomain
PF02791--DDT
PF00628--PHD
PF10537--WAC_Acf1_DNA_bd
PF15612--WHIM1
PF15613--WSD
PRINTS

PR00503--BROMODOMAIN
SMART

SM00297--BROMO
SM00571--DDT
SM00249--PHD
Gene Ontology

GO:0008623--C:CHRAC
GO:0000228--C:nuclear chromosome
GO:0008270--F:zinc ion binding
GO:0006338--P:chromatin remodeling
GO:0006261--P:DNA-dependent DNA replication
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002389 Ailuropoda melanoleuca 85.83 0.00e+00 2269.00
IUUC-Apl-004078 Anas platyrhynchos 72.10 0.00e+00 1888.00
IUUC-Aca-004951 Anolis carolinensis 75.99 0.00e+00 803.00
IUUC-Bta-012850 Bos taurus 88.66 0.00e+00 1640.00
IUUC-Cel-018523 Caenorhabditis elegans 46.38 3.00e-16 81.60
IUUC-Cja-018999 Callithrix jacchus 86.22 0.00e+00 1745.00
IUUC-Cfa-020916 Canis familiaris 89.72 0.00e+00 1872.00
IUUC-Cpo-022146 Cavia porcellus 79.40 0.00e+00 1632.00
IUUC-Csa-024039 Chlorocebus sabaeus 88.66 0.00e+00 1872.00
IUUC-Cho-024914 Choloepus hoffmanni 79.62 0.00e+00 1013.00
IUUC-Cin-025450 Ciona intestinalis 42.24 5.00e-42 165.00
IUUC-Csv-026068 Ciona savignyi 56.06 5.00e-39 153.00
IUUC-Dre-027413 Danio rerio 56.99 0.00e+00 723.00
IUUC-Dno-029438 Dasypus novemcinctus 88.40 0.00e+00 1268.00
IUUC-Dor-030774 Dipodomys ordii 74.55 6.00e-151 529.00
IUUC-Dme-031772 Drosophila melanogaster 30.50 7.00e-36 146.00
IUUC-Ete-033052 Echinops telfairi 80.59 0.00e+00 1553.00
IUUC-Eca-034262 Equus caballus 86.79 0.00e+00 2188.00
IUUC-Eeu-034704 Erinaceus europaeus 70.76 0.00e+00 683.00
IUUC-Fca-036207 Felis catus 84.95 0.00e+00 839.00
IUUC-Fal-036702 Ficedula albicollis 75.69 0.00e+00 1283.00
IUUC-Gmo-039218 Gadus morhua 51.09 2.00e-94 341.00
IUUC-Gga-040776 Gallus gallus 79.25 0.00e+00 1054.00
IUUC-Gac-042358 Gasterosteus aculeatus 53.31 0.00e+00 687.00
IUUC-Hsa-046560 Homo sapiens 89.31 0.00e+00 1915.00
IUUC-Itr-048135 Ictidomys tridecemlineatus 89.15 0.00e+00 1278.00
IUUC-Laf-054049 Loxodonta africana 85.84 0.00e+00 1758.00
IUUC-Mga-059382 Meleagris gallopavo 78.51 0.00e+00 1538.00
IUUC-Mmr-061301 Microcebus murinus 87.55 0.00e+00 1285.00
IUUC-Mdo-062889 Monodelphis domestica 81.01 0.00e+00 1083.00
IUUC-Mpu-066668 Mustela putorius furo 87.52 0.00e+00 2273.00
IUUC-Mlu-068089 Myotis lucifugus 87.13 0.00e+00 1782.00
IUUC-Nle-069936 Nomascus leucogenys 88.87 0.00e+00 1806.00
IUUC-Oan-073582 Ornithorhynchus anatinus 78.67 0.00e+00 1537.00
IUUC-Ocu-074115 Oryctolagus cuniculus 82.57 0.00e+00 2351.00
IUUC-Ogu-078790 Oryza glumaepatula 50.98 3.00e-13 69.70
IUUC-Ome-081195 Oryza meridionalis 50.98 3.00e-13 69.70
IUUC-Oru-084688 Oryza rufipogon 50.98 3.00e-13 69.70
IUUC-Ola-086709 Oryzias latipes 51.60 0.00e+00 923.00
IUUC-Oga-088100 Otolemur garnettii 84.07 0.00e+00 1201.00
IUUC-Oar-089208 Ovis aries 88.16 0.00e+00 1774.00
IUUC-Ptr-090630 Pan troglodytes 89.31 0.00e+00 1885.00
IUUC-Pan-092146 Papio anubis 85.35 0.00e+00 1279.00
IUUC-Psi-092932 Pelodiscus sinensis 74.39 0.00e+00 1400.00
IUUC-Pfo-096572 Poecilia formosa 55.76 0.00e+00 734.00
IUUC-Pva-102893 Pteropus vampyrus 89.31 0.00e+00 1823.00
IUUC-Rno-105098 Rattus norvegicus 94.03 0.00e+00 2355.00
IUUC-Sha-106513 Sarcophilus harrisii 81.84 0.00e+00 1124.00
IUUC-Sar-113192 Sorex araneus 91.33 5.00e-102 366.00
IUUC-Ssc-116407 Sus scrofa 89.30 0.00e+00 1283.00
IUUC-Tgu-117403 Taeniopygia guttata 77.87 0.00e+00 1593.00
IUUC-Tru-118124 Takifugu rubripes 53.78 0.00e+00 675.00
IUUC-Tsy-119386 Tarsius syrichta 82.61 0.00e+00 1219.00
IUUC-Vpa-130046 Vicugna pacos 84.89 0.00e+00 2093.00
IUUC-Xtr-132132 Xenopus tropicalis 56.78 1.00e-104 375.00
Created Date 25-Jun-2017

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