iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fox-037866

Ensembl Protein ID

FOXG_08629P0

UniProt Accession

A0A0D2XXB3; A0A0D2XXB3_FUSO4

Genbank Protein ID

KNB07485.1

Protein Name

Phosphatidylethanolamine N-methyltransferase

Genbank Nucleotide ID

DS231705

Gene Name

FOXG_08629

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FOXG_08629	FOXG_08629T0	FOXG_08629P0

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/U-box	39.66	1.30e+00	32.70	IUUC-Oin-079232

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Fusarium oxysporum

Functional Description
(View)

Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).

Protein Sequence
(Fasta)

MVSQLLDPRQ PKNLSDAIVL TILGLHILAA YFLPSSSKRI VFAAVFLFWR ACYNIGIGVL 60
LQIQSNHRRL VTWARRWKLF ENPSTGKNPR PWLYKLLKNE LETKIPEDYE FEKAPIEYNT 120

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Nucleotide Sequence
(Fasta)

TGCCAGTTCG TCGCCGTCTT TCTTGGATAC CACTTGTCGC CATCGTACCA CGCTCTCTCT 60
GCTGAATCGT CGCCAGTCAT GAGTACTGCC GCCGATCTGC CTGCCACTGG CCCTGGGCTT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0444--Lipid biosynthesis
KW-0443--Lipid metabolism
KW-0472--Membrane
KW-0489--Methyltransferase
KW-0594--Phospholipid biosynthesis
KW-1208--Phospholipid metabolism
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR007318--Phopholipid_MeTrfase
IPR016219--Phosphatid-EA_MeTrfase_fun

PROSITE

PS51598--SAM_CHO2

Pfam

PF04191--PEMT

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0004608--F:phosphatidylethanolamine N-methyltransferase activity
GO:0006656--P:phosphatidylcholine biosynthetic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dre-028180	Danio rerio	25.64	1.90e-02	35.40
IUUC-Oba-075116	Oryza barthii	37.93	9.00e-03	32.00
IUUC-Oin-079232	Oryza indica	39.66	1.00e-02	32.70
IUUC-Oni-082736	Oryza nivara	37.93	6.60e-02	30.00
IUUC-Ola-087063	Oryzias latipes	32.14	2.70e-01	28.90
IUUC-Olu-087743	Ostreococcus lucimarinus	30.43	1.10e-01	29.60
IUUC-Ppe-101547	Prunus persica	36.11	6.70e-01	27.30
IUUC-Sit-109818	Setaria italica	32.56	4.60e-01	27.70

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence