iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052620

Ensembl Protein ID

ENSLOCP00000006084.1

UniProt Accession

W5MCH5; W5MCH5_LEPOC

Genbank Protein ID

ENSLOCP00000006084

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AHAT01009602

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000005054.1	ENSLOCT00000006092.1	ENSLOCP00000006084.1
ENSLOCG00000005054.1	ENSLOCT00000006111.1	ENSLOCP00000006103.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.30e-16	59.1	91	146

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +lydy+a ++d+Lt++kG++ ++i  ++++++W+++ + ++g +G +P+n+v+ ++
   Q: 91   FVALYDYDARTEDDLTFRKGEKFHII--NNTEGDWWEARSLDTGNSGYIPSNYVAPVD 146
           789***********************..8999**********************9987 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

RMGCVHCKEK ASSKAQGVVA DGNPQASNPR YGPDPTNQSQ QSNFSRIPDF NNFSGTTVPA 60
ATPFGALSSY PSATLQSRGG GGITGGGVTL FVALYDYDAR TEDDLTFRKG EKFHIINNTE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAATGGGCT GTGTGCACTG CAAAGAGAAG GCCTCCTCCA AGGCCCAGGG AGTGGTGGCT 60
GATGGGAACC CACAGGCCTC TAACCCACGC TACGGCCCCG ATCCAACGAA TCAGAGCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0048246--P:macrophage chemotaxis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004483	Anolis carolinensis	85.69	0.00e+00	946.00
IUUC-Ame-011816	Astyanax mexicanus	83.15	0.00e+00	915.00
IUUC-Dre-028216	Danio rerio	84.59	0.00e+00	934.00
IUUC-Eca-033581	Equus caballus	72.83	0.00e+00	804.00
IUUC-Fal-036786	Ficedula albicollis	87.53	0.00e+00	905.00
IUUC-Gga-040762	Gallus gallus	83.67	0.00e+00	926.00
IUUC-Gac-041918	Gasterosteus aculeatus	83.62	0.00e+00	893.00
IUUC-Lpe-051166	Leersia perrieri	35.15	7.00e-24	105.00
IUUC-Meu-056155	Macropus eugenii	78.10	0.00e+00	726.00
IUUC-Oba-075994	Oryza barthii	34.65	1.00e-21	98.60
IUUC-Ola-086657	Oryzias latipes	85.05	0.00e+00	906.00
IUUC-Ppe-102072	Prunus persica	31.43	2.00e-25	110.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence